Standard name
Human Ortholog
Description Endoplasmic reticulum (ER) resident protein; required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.07 0.07 0.09 0.08 0.08 0.11 – 0.1 0.09 0.1 0.05 0.05 0 0.06 0.05 0.17 0.09 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0.05 0.06 0.1 0.08 0.08 0.07 0.08 – 0.12 0.08 0.09 0.1 0.17 0.23 0.34 0.26 0.26 0 0 0 0 0 0
Cytoplasm 0.28 0.07 0 0.07 0.08 0.07 0.08 0.09 – 0.09 0.09 0.06 0.05 0.05 0.08 0.24 0.24 0.26 0 0 0 0 0 0
Endoplasmic Reticulum 0.59 0.86 0.89 0.75 0.76 0.77 0.7 0.69 – 0.6 0.53 0.65 0.85 0.88 0.8 0 0 0 0.76 0.91 0.93 0.91 0.85 0.86
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0.07 0 0.07 0.19 0.08 0 0 0 – 0 0 0 0 0 0 0.34 0.48 0.33 0 0 0 0 0 0
Mitochondria 0 0 0.14 0.05 0.11 0.16 0.17 0.22 – 0.19 0.34 0.3 0 0 0 0.07 0.07 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0.05 0.09 – 0.07 0.07 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.07 0.1 0 0.13 0.08 0.05 0.12 0 – 0.11 0.08 0.05 0.08 0 0.05 0.16 0.05 0.15 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 2 20 14 14 29 22 32 39 – 34 27 39 13 19 10 7 4 8 10 9 2 1 8 4
Bud 1 0 2 1 1 0 5 9 – 6 6 5 1 1 0 0 0 0 1 7 1 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 35 12 20 26 21 30 27 – 41 24 36 23 64 87 41 23 12 0 3 1 0 2 5
Cytoplasm 29 46 9 14 24 18 33 30 – 28 27 22 13 19 31 29 21 12 2 8 0 2 5 3
Endoplasmic Reticulum 61 549 192 150 243 212 292 241 – 196 155 256 201 340 302 2 0 0 88 614 213 212 244 281
Endosome 0 0 0 1 1 1 0 1 – 2 0 0 0 0 0 0 0 0 4 2 0 1 2 0
Golgi 7 26 15 38 25 4 5 1 – 2 2 7 10 13 8 42 42 15 0 2 2 2 6 2
Mitochondria 0 2 31 10 34 43 71 75 – 63 98 119 0 0 1 8 6 3 2 2 4 3 4 6
Nucleus 2 0 0 0 3 3 0 1 – 3 1 1 0 1 0 0 0 0 0 2 0 0 0 0
Nuclear Periphery 2 3 6 4 6 12 22 30 – 23 19 31 1 3 4 0 3 0 1 3 1 1 2 1
Nucleolus 5 0 1 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0
Vac/Vac Membrane 7 64 8 26 26 13 49 15 – 36 24 19 19 14 20 19 4 7 0 8 1 3 6 13
Unique Cell Count 103 639 215 201 318 276 417 348 328 291 393 237 386 377 122 88 46 117 676 231 234 288 326
Labelled Cell Count 117 745 290 278 418 349 539 469 434 383 536 281 474 463 148 103 57 117 676 231 234 288 326


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 20.7 25.9 19.3 20.0 17.4 14.9 14.2 14.0 – 13.8 13.6 14.0 26.7 26.1 25.5 28.7 26.9 29.1 26.3 25.1 28.2
Std Deviation (1e-4) 10.1 8.4 6.4 6.1 5.1 4.0 3.2 3.5 – 3.6 3.4 3.5 10.0 8.0 8.1 10.1 8.7 11.6 9.1 8.3 9.7
Intensity Change (Log2) – – – 0.05 -0.15 -0.37 -0.44 -0.46 – -0.48 -0.51 -0.46 0.47 0.44 0.41 0.58 0.48 0.6 0.45 0.38 0.55

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.2 1.1 0.6 0.5 1.9 – 1.5 1.1 1.4 -0.5 -0.8 -2.3 -0.3 -0.7 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 1.7 1.1 0.9 0.8 1.0 – 2.7 1.2 1.6 1.6 3.9 5.5 6.8 5.1 0
Cytoplasm 1.2 1.6 1.1 1.8 2.0 – 2.0 2.2 0.8 0.6 0.4 1.9 5.5 5.2 0
Endoplasmic Reticulum -3.9 -3.8 -3.6 -5.4 -5.5 – -7.5 -8.6 -6.5 -1.4 -0.4 -2.9 -15.6 -14.6 -12.5
Endosome 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Golgi 3.6 0.4 -3.2 -3.9 -4.6 – -4.2 -3.9 -3.3 -1.3 -2.0 -2.9 6.5 8.2 4.9
Mitochondria -3.2 -1.3 0.4 0.8 2.1 – 1.4 4.9 4.3 -6.1 -7.7 -7.3 -2.2 -1.8 -1.4
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0.9 1.4 2.7 – 2.1 1.9 2.5 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole 3.4 2.1 0.5 3.3 0.3 – 3.0 2.1 0.6 1.9 -0.1 0.9 3.9 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 16.4505 17.9481 16.0681 14.046 14.2893 15.7962 22.911 22.4968 22.0767 18.9942 20.2072 21.408 22.8188 19.3027 19.7992 19.3829 19.3378 19.7252
Actin 0.0058 0.0005 0.0047 0.005 0.0002 0.0048 0.0021 0.0003 0.0003 0 0.0027 0.001 0.0001 0.0007 0 0 0 0.0001
Bud 0.0001 0 0.0002 0.0002 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0.0005 0.0006 0.0003 0.0002 0.0003 0.0003 0.0001 0.0001 0.0003 0 0.0002 0.0001 0 0.0002 0 0.0001 0 0.0006
Bud Periphery 0.0002 0.0001 0.0003 0.0002 0.0001 0.0002 0.0001 0 0.0001 0 0 0 0 0.0002 0 0 0 0
Bud Site 0.0009 0.0002 0.0034 0.001 0.0002 0.0001 0.0002 0 0 0 0 0 0 0.0005 0 0 0 0
Cell Periphery 0.0025 0.0057 0.0046 0.0018 0.0013 0.0008 0.0015 0.0009 0.0025 0.0002 0.0005 0.0004 0.0011 0.0051 0.0016 0.0018 0.0007 0.0008
Cytoplasm 0.0126 0.0132 0.0057 0.0024 0.0021 0.0053 0.0023 0.0067 0.002 0.0002 0.0055 0.0013 0.0067 0.0307 0.0031 0.001 0.0013 0.0042
Cytoplasmic Foci 0.0062 0.0007 0.0006 0.0038 0.0038 0.0009 0.005 0.0001 0.0001 0 0.0011 0.0007 0.0001 0.0015 0.0001 0 0 0
Eisosomes 0.0004 0.0001 0.0004 0.0001 0 0.0001 0.0001 0 0 0 0.0001 0 0 0.0001 0 0 0 0
Endoplasmic Reticulum 0.8598 0.941 0.9299 0.9002 0.9494 0.9499 0.9288 0.9827 0.9831 0.9972 0.9381 0.9889 0.9418 0.9138 0.9865 0.9905 0.9881 0.9751
Endosome 0.0099 0.0016 0.0082 0.0222 0.0078 0.0057 0.004 0.0005 0.0008 0.0001 0.0052 0.0015 0.0004 0.0027 0.0002 0.0002 0.0004 0.0007
Golgi 0.004 0.0004 0.0057 0.0055 0.0014 0.0043 0.0013 0.0002 0.0043 0 0.0152 0.0005 0.0001 0.0006 0.0001 0.0001 0.0001 0.0003
Lipid Particles 0.0128 0.0112 0.0023 0.0066 0.0136 0.0028 0.0052 0.002 0.0009 0 0.0107 0.0002 0.0011 0.0129 0.0013 0.0002 0.0007 0.0003
Mitochondria 0.0091 0.0002 0.0084 0.0103 0.0004 0.002 0.0011 0.0001 0.0001 0 0.0003 0.0001 0.0002 0.0001 0 0 0 0
None 0.0019 0.0008 0.0002 0.0005 0.0003 0.0004 0.0016 0 0 0 0.0004 0.0001 0 0.0002 0 0 0 0
Nuclear Periphery 0.0507 0.012 0.0167 0.0325 0.0104 0.0168 0.0359 0.005 0.0042 0.0017 0.0146 0.0043 0.0429 0.0232 0.0056 0.0046 0.0071 0.0129
Nucleolus 0.0004 0.0002 0.0001 0.0002 0.0004 0 0 0 0 0 0.0001 0 0 0 0 0 0 0
Nucleus 0.0046 0.0034 0.0009 0.0012 0.0006 0.0019 0.0036 0.0002 0.0001 0 0.0024 0.0001 0.003 0.0029 0.0001 0.0002 0.0002 0.0019
Peroxisomes 0.0067 0 0.0001 0.0007 0.0025 0.0002 0.0015 0 0 0 0 0.0001 0 0 0 0 0 0
Punctate Nuclear 0.0019 0.0008 0.0001 0.0006 0.0027 0.0005 0.0007 0 0 0 0.0013 0.0001 0 0.0003 0 0 0 0
Vacuole 0.0062 0.007 0.0047 0.0027 0.0024 0.0023 0.0029 0.001 0.001 0.0005 0.0011 0.0006 0.0017 0.004 0.0011 0.0011 0.0013 0.0027
Vacuole Periphery 0.0029 0.0003 0.0027 0.0021 0.0003 0.0006 0.0019 0.0002 0.0002 0 0.0005 0.0001 0.0007 0.0004 0.0001 0.0002 0.0001 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 116.7062 112.7588 143.8844 159.9761 116.925 130.78 141.181 158.5731 154.849 160.6324
Translational Efficiency 1.2495 1.4528 1.352 1.2485 1.1844 1.2939 1.3394 1.1037 1.3598 1.1258

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2152 1878 2117 1754 1697 1575 2237 1543 3849 3453 4354 3297

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2350.74 2060.65 2163.60 2609.02 2196.64 1538.23 2234.15 2593.50 2282.80 1822.36 2199.85 2601.76
Standard Deviation 423.75 531.54 393.63 531.64 416.46 347.87 382.87 514.36 427.45 525.90 389.73 523.68
Intensity Change Log 2 — -0.190015 -0.119681 0.150393 — -0.514027 0.024428 0.239602 — -0.337488 -0.048270 0.194175

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000483 0.000579 0.000333 0.001752 0.000687 0.001324 0.000778 0.001024 0.000573 0.000919 0.000561 0.001412
Bud Neck 0.000157 0.000167 0.000715 0.005243 0.000278 0.000223 0.000706 0.003398 0.000210 0.000193 0.000711 0.004380
Bud Site 0.000544 0.000866 0.001416 0.013427 0.000436 0.002456 0.002566 0.008907 0.000497 0.001591 0.002007 0.011311
Cell Periphery 0.002147 0.002041 0.004119 0.010844 0.003643 0.002931 0.005394 0.014440 0.002807 0.002447 0.004774 0.012527
Cytoplasm 0.000212 0.000891 0.001757 0.009183 0.000537 0.002735 0.003160 0.004091 0.000356 0.001732 0.002478 0.006800
Cytoplasmic Foci 0.000357 0.000263 0.000116 0.002891 0.000167 0.000700 0.000686 0.001470 0.000274 0.000462 0.000409 0.002226
Eisosomes 0.000284 0.000087 0.000034 0.000249 0.000698 0.000163 0.000049 0.000185 0.000467 0.000122 0.000041 0.000219
Endoplasmic Reticulum 0.985732 0.983160 0.970830 0.831516 0.976958 0.968746 0.958721 0.867278 0.981864 0.976585 0.964609 0.848253
Endosome 0.001954 0.003334 0.003989 0.017915 0.003068 0.006672 0.004780 0.014413 0.002445 0.004856 0.004395 0.016276
Golgi 0.002203 0.001137 0.001270 0.010198 0.004871 0.001967 0.003154 0.008571 0.003379 0.001515 0.002238 0.009436
Lipid Particles 0.001488 0.001394 0.003328 0.031429 0.001677 0.004184 0.005175 0.025187 0.001572 0.002666 0.004277 0.028508
Mitochondria 0.000312 0.000469 0.000251 0.001973 0.000765 0.000445 0.000808 0.001889 0.000512 0.000458 0.000537 0.001934
Mitotic Spindle 0.000013 0.000223 0.000055 0.003292 0.000026 0.000137 0.000400 0.000823 0.000019 0.000184 0.000232 0.002137
None 0.000304 0.000773 0.000398 0.002506 0.000178 0.000897 0.001070 0.002102 0.000248 0.000829 0.000743 0.002317
Nuclear Periphery 0.000870 0.000683 0.002101 0.004112 0.001052 0.000869 0.001523 0.003459 0.000950 0.000768 0.001804 0.003806
Nuclear Periphery Foci 0.000496 0.001669 0.004178 0.027828 0.001202 0.003722 0.003601 0.016292 0.000807 0.002605 0.003881 0.022429
Nucleolus 0.000016 0.000017 0.000005 0.000047 0.000006 0.000005 0.000008 0.000028 0.000011 0.000012 0.000007 0.000038
Nucleus 0.000357 0.000085 0.000116 0.001107 0.000049 0.000114 0.000132 0.000561 0.000221 0.000098 0.000124 0.000852
Peroxisomes 0.000048 0.000056 0.000023 0.000095 0.000035 0.000149 0.000102 0.000060 0.000042 0.000098 0.000064 0.000079
Vacuole 0.001261 0.001668 0.004280 0.019610 0.002247 0.001181 0.005802 0.020372 0.001696 0.001446 0.005062 0.019966
Vacuole Periphery 0.000761 0.000438 0.000686 0.004783 0.001419 0.000381 0.001386 0.005449 0.001051 0.000412 0.001046 0.005095

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.25 0.10 -3.60 -3.18 -3.90 -1.06 -0.23 -1.14 0.10 -0.99 -1.04 -0.23 -3.32 -2.30 -3.24
Bud Neck -0.06 -3.81 -8.72 -8.73 -7.57 0.65 -2.35 -7.14 -7.33 -5.65 0.40 -4.22 -11.18 -11.29 -9.41
Bud Site -0.77 -2.33 -9.11 -8.87 -8.12 -3.07 -3.84 -6.75 -4.94 -4.64 -2.92 -4.39 -11.31 -9.95 -9.10
Cell Periphery 0.30 -4.17 -8.65 -8.70 -6.34 1.21 -2.48 -7.78 -8.15 -6.12 1.10 -4.65 -11.59 -11.86 -8.66
Cytoplasm -3.32 -6.89 -8.52 -7.83 -6.92 -2.63 -3.35 -4.30 -2.21 -1.49 -3.60 -5.49 -9.45 -7.59 -6.19
Cytoplasmic Foci 0.46 0.90 -4.21 -5.23 -5.57 -3.21 -3.29 -3.84 -2.09 -2.10 -0.76 -0.55 -5.40 -5.54 -5.70
Eisosomes 1.30 1.66 0.19 -1.52 -2.04 1.45 1.77 1.38 -0.41 -3.39 1.88 2.33 1.28 -1.55 -3.03
Endoplasmic Reticulum 1.27 6.69 23.42 22.70 20.31 2.39 5.83 17.20 15.51 13.58 2.73 9.03 28.99 27.29 24.02
Endosome -4.37 -6.85 -19.18 -16.78 -15.97 -5.67 -4.27 -14.32 -8.21 -11.39 -7.16 -7.84 -23.94 -17.86 -19.41
Golgi 4.51 3.60 -6.86 -7.83 -7.67 4.22 2.30 -3.88 -6.59 -5.23 5.53 2.91 -7.95 -10.25 -9.06
Lipid Particles 0.13 -2.90 -12.02 -12.08 -11.02 -2.71 -4.57 -10.36 -8.74 -8.41 -2.34 -5.36 -15.85 -14.89 -13.78
Mitochondria -0.93 0.43 -3.97 -3.57 -4.17 0.80 -0.17 -1.82 -2.83 -2.01 0.32 -0.23 -3.92 -4.51 -4.15
Mitotic Spindle -1.27 -3.49 -5.05 -4.61 -4.96 -1.26 -2.00 -3.74 -3.06 -1.47 -1.66 -2.28 -5.87 -5.28 -5.08
None -1.85 -0.75 -4.49 -3.30 -4.36 -3.20 -3.65 -2.83 -1.70 -1.40 -3.37 -3.45 -5.03 -3.43 -3.66
Nuclear Periphery 1.26 -4.11 -9.54 -9.54 -4.36 1.03 -2.78 -7.57 -7.64 -5.64 1.59 -5.05 -12.21 -12.23 -6.98
Nuclear Periphery Foci -2.98 -5.75 -13.63 -12.75 -11.07 -4.22 -4.06 -8.85 -7.21 -7.08 -5.17 -7.13 -16.19 -14.49 -13.13
Nucleolus 0.11 1.00 -2.18 -2.42 -5.73 0.20 -1.44 -4.59 -4.44 -4.06 0.15 0.82 -3.33 -3.70 -6.99
Nucleus 1.04 0.69 -2.43 -5.72 -5.07 -1.69 -3.38 -4.68 -4.26 -4.07 0.89 0.47 -3.72 -7.12 -6.49
Peroxisomes -0.27 1.03 -1.51 -1.55 -3.38 -1.92 -2.48 -1.48 1.53 1.66 -1.79 -1.11 -1.93 0.66 -0.87
Vacuole -1.08 -6.73 -12.79 -12.18 -10.21 1.87 -4.68 -9.72 -10.62 -7.62 0.67 -7.80 -15.78 -16.05 -12.39
Vacuole Periphery 1.80 0.33 -6.46 -7.09 -6.64 4.80 -0.10 -5.24 -6.77 -4.94 4.58 -0.16 -8.28 -9.79 -7.95
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Endoplasmic reticulum (ER) resident protein; required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages ER (99%)
Cell Cycle Regulation No
Subcompartmental Group ER-5

Pho86

Pho86


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pho86-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available