Standard name
Human Ortholog
Description Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0 0 0.05 0 0 0 0 0 0 0 0 0.05 0.1 0.14 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.08 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.9 0.93 0.94 0.71 0.87 0.77 0.84 0.77 0.8 0.82 0.82 0.77 0.9 0.83 0.71 0.82 0.76 0.79 0.93 0.94 0.96 0.8 0.74 0.66
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0.29 0.06 0.08 0.07 0.12 0.1 0.09 0.12 0.12 0 0.08 0.14 0 0.05 0 0 0 0 0.05 0.07 0.09
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.08 0.05 0 0 0 0.11 0.06 0.12 0.09 0.07 0.06 0.08 0 0 0 0.14 0.18 0.17 0 0 0 0.13 0.16 0.21
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 0 0 0 0 0 0 0 4 0 0 1 0 0 0 0 0 0
Bud 0 0 0 0 1 1 0 1 0 2 1 0 0 1 3 0 0 1 4 0 0 2 6 13
Bud Neck 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 1 0 1 2 2 1 4 0 0 4 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 12 4 5 14 19 15 23 16 15 18 15 15 43 102 161 4 8 8 0 0 0 4 3 4
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 2 2 1 0 0 0 0 0
Endosome 0 0 0 0 0 3 2 6 1 5 4 2 0 8 15 2 4 1 2 0 0 5 4 11
Golgi 0 0 0 0 1 0 1 0 0 0 0 0 0 0 2 1 3 2 0 0 0 3 1 0
Mitochondria 1 0 0 0 0 26 1 12 8 16 17 28 2 2 4 3 2 2 0 0 0 0 6 5
Nucleus 216 182 117 207 405 267 508 591 347 515 363 406 716 878 835 268 236 256 228 182 123 679 815 752
Nuclear Periphery 0 0 0 0 9 3 8 5 8 15 5 4 0 8 4 0 1 0 0 0 0 1 3 4
Nucleolus 2 0 0 84 30 27 40 91 43 58 53 63 21 83 160 14 15 14 3 0 0 43 79 100
Peroxisomes 0 0 0 0 0 0 0 1 0 0 0 0 0 5 10 1 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 3 2 0 2 1 1 0 8 25 1 1 0 0 0 0 1 1 9
Vac/Vac Membrane 19 10 4 7 15 37 37 92 39 47 25 43 26 28 40 46 56 55 3 8 2 107 177 240
Unique Cell Count 240 195 125 290 463 346 603 767 434 631 442 524 792 1063 1177 328 311 325 246 193 129 854 1106 1147
Labelled Cell Count 250 196 126 312 481 380 623 820 463 680 485 566 809 1123 1267 343 328 342 246 193 129 854 1106 1147


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 18.6 19.5 18.6 19.2 15.8 9.0 11.0 10.2 10.3 10.2 10.0 9.8 21.3 20.7 18.5 26.0 23.6 27.3 19.5 19.0 19.0
Std Deviation (1e-4) 5.1 4.0 4.5 5.9 5.7 2.6 2.2 2.4 3.2 3.1 2.7 2.4 6.8 9.6 9.2 7.2 7.6 7.7 5.1 5.8 5.4
Intensity Change (Log2) – – – 0.05 -0.24 -1.05 -0.75 -0.87 -0.86 -0.87 -0.9 -0.93 0.2 0.15 -0.01 0.48 0.34 0.55 0.07 0.03 0.03

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000102030WT3HU80HU120HU1600102030WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30102030WT1AF100AF140AF1800102030
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.4 0.1 0.2 0 0 0 0 0 0 0.7 2.1 3.1 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 3.2 0 0 0 0 0 2.6 0 0 0 0 0 0
Nucleus -5.0 -1.9 -4.1 -2.7 -4.2 -3.6 -3.3 -3.1 -4.1 -1.2 -3.2 -5.4 -3.2 -4.3 -3.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 6.7 2.9 3.2 3.0 4.1 3.7 3.5 4.1 4.1 0 3.2 4.4 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 2.5 1.3 2.9 2.1 1.7 1.1 1.9 0 0 0 3.3 4.1 3.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 11.7142 12.4733 11.7294 10.8727 10.8079 11.1472 14.6811 17.7284 15.8983 14.6346 17.3182 15.7497 14.8309 19.0877 17.4569 16.273 15.3455 17.0684
Actin 0.0001 0 0 0 0 0 0.0088 0.0001 0.0017 0.0012 0.0008 0.0002 0.0283 0 0.0046 0.015 0.0026 0.0071
Bud 0 0 0 0 0 0 0.0003 0.0001 0.0001 0.0002 0 0.0001 0.0006 0 0.0001 0.0007 0.0003 0.0003
Bud Neck 0.0001 0.0001 0.0001 0.001 0.0006 0.0005 0.0004 0.0001 0.0001 0.0002 0.0001 0.0007 0.0008 0.0001 0.0003 0.0001 0.0015 0.0007
Bud Periphery 0.0001 0 0 0.0002 0.0001 0 0.0004 0.0002 0.0003 0.0004 0 0.0001 0.0013 0 0.0003 0.0006 0.0004 0.0008
Bud Site 0.0001 0 0 0 0 0 0.0008 0.0005 0.0003 0.0005 0 0.0001 0.0017 0.0001 0.0006 0.003 0.001 0.0006
Cell Periphery 0 0 0 0 0 0 0.0003 0.0002 0.0002 0.0006 0 0.0001 0.0007 0 0.0002 0.0003 0.0002 0.0001
Cytoplasm 0.0024 0.0001 0.0001 0.0001 0.0001 0.0001 0.0013 0.0007 0.0012 0.0017 0.0001 0.0013 0.0097 0.0042 0.0068 0.003 0.0017 0.0008
Cytoplasmic Foci 0.0003 0 0 0 0 0 0.0103 0.0001 0.0036 0.0054 0.0007 0.003 0.0087 0 0.0123 0.0243 0.003 0.0011
Eisosomes 0 0 0 0 0 0 0.0001 0 0.0001 0 0 0 0.0006 0 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0003 0 0 0.0001 0 0 0.0014 0 0.0005 0.0019 0.0004 0.0003 0.0036 0 0.0022 0.0014 0.0028 0.0003
Endosome 0.0008 0 0 0 0.0001 0 0.0077 0.0001 0.0015 0.0085 0.0119 0.0027 0.015 0 0.0053 0.0026 0.0277 0.0029
Golgi 0 0 0 0 0 0 0.0046 0 0.0006 0.0008 0.0202 0.0016 0.0033 0 0.0021 0.0014 0.0041 0.0021
Lipid Particles 0.0004 0 0 0 0 0 0.0154 0.0002 0.0029 0.0047 0.0048 0.0032 0.0081 0 0.011 0.0078 0.0105 0.0022
Mitochondria 0.0003 0.0001 0.0002 0.0001 0.0003 0.0001 0.0061 0.0008 0.0077 0.005 0.0017 0.0006 0.0069 0.0003 0.0049 0.0056 0.0018 0.0019
None 0.0002 0 0 0 0 0 0.001 0 0.0005 0.0012 0 0.0003 0.0042 0 0.0055 0.0049 0.0014 0.0003
Nuclear Periphery 0.0048 0.0027 0.0032 0.006 0.003 0.001 0.0102 0.0043 0.0051 0.0284 0.002 0.0039 0.0195 0.0076 0.0082 0.0039 0.0107 0.0034
Nucleolus 0.0156 0.0131 0.0141 0.0095 0.0145 0.0251 0.0343 0.0139 0.0314 0.0295 0.0072 0.0299 0.0376 0.0151 0.0328 0.0039 0.0296 0.0259
Nucleus 0.9721 0.9836 0.9819 0.9798 0.9801 0.9727 0.8652 0.9765 0.9348 0.8799 0.9487 0.9449 0.822 0.9716 0.8843 0.8975 0.8917 0.9413
Peroxisomes 0 0 0 0 0 0 0.014 0 0.0008 0.0002 0.0001 0.0008 0.0011 0 0.0099 0.0134 0.0009 0.0005
Punctate Nuclear 0.0017 0.0001 0.0001 0.0017 0.0005 0.0002 0.0121 0.0002 0.0009 0.0169 0.0002 0.0042 0.0146 0.0001 0.006 0.0064 0.0015 0.0023
Vacuole 0.0004 0.0001 0.0002 0.0011 0.0003 0.0001 0.0028 0.0013 0.0036 0.0086 0.0003 0.0014 0.0079 0.0004 0.0012 0.0024 0.0048 0.0041
Vacuole Periphery 0.0003 0.0001 0.0002 0.0003 0.0002 0.0001 0.0025 0.0006 0.0023 0.0041 0.0006 0.0005 0.0038 0.0004 0.0015 0.0015 0.0018 0.0011

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 112.8482 110.2201 90.1055 59.3285 90.768 100.254 57.6106 44.6201 42.9226 73.6614
Translational Efficiency 2.4348 2.332 2.17 2.9472 2.2866 1.8726 2.1581 2.9489 2.0329 2.0513

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1651 1243 328 225 1021 1905 1934 1922 2672 3148 2262 2147

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1317.20 1506.85 1851.71 2256.11 1297.10 1515.78 1924.50 1873.47 1309.52 1512.25 1913.95 1913.57
Standard Deviation 254.36 353.32 264.65 411.01 249.18 281.57 368.59 452.73 252.58 311.91 356.33 463.60
Intensity Change Log 2 — 0.194061 0.491384 0.776363 — 0.224771 0.569194 0.530423 — 0.209380 0.530514 0.659570

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000460 0.000644 0.000802 0.001218 0.000638 0.000435 0.000568 0.000759 0.000528 0.000517 0.000602 0.000807
Bud Neck 0.007697 0.012362 0.015482 0.026918 0.008585 0.013643 0.013527 0.021486 0.008036 0.013137 0.013810 0.022055
Bud Site 0.000510 0.001079 0.000843 0.001316 0.000643 0.000900 0.000479 0.000821 0.000560 0.000971 0.000531 0.000873
Cell Periphery 0.000178 0.000137 0.000046 0.000048 0.000150 0.000614 0.000071 0.000071 0.000167 0.000426 0.000067 0.000068
Cytoplasm 0.000381 0.002285 0.000256 0.000208 0.000405 0.000706 0.000321 0.000562 0.000390 0.001329 0.000312 0.000525
Cytoplasmic Foci 0.000044 0.000649 0.000074 0.000351 0.000197 0.000071 0.000028 0.000191 0.000103 0.000299 0.000035 0.000208
Eisosomes 0.000042 0.000041 0.000056 0.000052 0.000040 0.000056 0.000039 0.000029 0.000041 0.000050 0.000042 0.000032
Endoplasmic Reticulum 0.004498 0.002005 0.001075 0.000827 0.003498 0.004100 0.001173 0.001138 0.004116 0.003273 0.001159 0.001106
Endosome 0.000103 0.000276 0.000037 0.000063 0.000183 0.000361 0.000029 0.000449 0.000134 0.000327 0.000030 0.000409
Golgi 0.000043 0.000280 0.000054 0.000163 0.000084 0.000106 0.000023 0.000612 0.000059 0.000174 0.000027 0.000565
Lipid Particles 0.000010 0.000223 0.000030 0.000043 0.000305 0.000017 0.000006 0.000047 0.000123 0.000098 0.000009 0.000047
Mitochondria 0.000734 0.001644 0.001896 0.005211 0.000902 0.001311 0.001574 0.002385 0.000798 0.001443 0.001621 0.002681
Mitotic Spindle 0.000372 0.001529 0.000044 0.005444 0.000482 0.000506 0.000170 0.000374 0.000414 0.000910 0.000151 0.000905
None 0.000744 0.002594 0.000578 0.000906 0.002551 0.000996 0.000545 0.001294 0.001435 0.001627 0.000550 0.001253
Nuclear Periphery 0.000244 0.000233 0.000175 0.001037 0.000237 0.000393 0.000442 0.000784 0.000242 0.000330 0.000403 0.000810
Nuclear Periphery Foci 0.000054 0.000309 0.000013 0.000132 0.000372 0.000524 0.000013 0.000158 0.000176 0.000439 0.000013 0.000155
Nucleolus 0.006432 0.025182 0.011129 0.165630 0.023324 0.019227 0.015627 0.060121 0.012886 0.021578 0.014975 0.071178
Nucleus 0.976595 0.946260 0.965708 0.784306 0.956043 0.953602 0.964515 0.906018 0.968742 0.950703 0.964688 0.893263
Peroxisomes 0.000129 0.000659 0.000802 0.003914 0.000540 0.000152 0.000231 0.000555 0.000286 0.000352 0.000314 0.000907
Vacuole 0.000589 0.001064 0.000795 0.001343 0.000661 0.001647 0.000390 0.001123 0.000616 0.001417 0.000449 0.001146
Vacuole Periphery 0.000143 0.000547 0.000104 0.000869 0.000160 0.000633 0.000228 0.001022 0.000149 0.000599 0.000210 0.001006

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.44 -6.62 -9.91 -7.80 -2.55 4.87 1.65 -2.67 -7.28 -4.63 0.21 -3.62 -6.93 -7.60 -4.68
Bud Neck -5.38 -7.39 -8.89 -6.94 -5.37 -5.00 -6.73 -14.45 -9.05 -9.17 -7.66 -10.20 -18.23 -11.53 -10.33
Bud Site -2.33 -4.53 -5.70 -2.52 -3.12 -1.12 1.08 -1.04 0.51 -5.35 -2.58 -0.24 -4.29 0.12 -5.77
Cell Periphery 0.96 3.38 3.38 3.72 0.02 -1.41 1.57 1.67 1.68 0.20 -1.30 3.16 3.36 1.83 0.16
Cytoplasm -3.19 0.19 1.49 3.47 1.28 -1.05 0.83 -0.55 0.85 -3.05 -3.45 0.71 -1.27 3.09 -2.85
Cytoplasmic Foci -2.72 -1.62 -2.91 0.35 -2.65 1.01 1.17 0.62 -1.12 -1.74 -1.01 1.15 -0.40 0.74 -2.29
Eisosomes 0.03 -3.40 -3.02 -3.64 0.68 -3.44 0.01 4.29 5.81 5.22 -2.60 -0.73 3.04 5.82 5.54
Endoplasmic Reticulum 9.81 13.43 15.24 7.22 3.37 -2.16 13.70 15.11 12.62 0.46 4.03 18.03 19.78 13.99 1.13
Endosome -2.52 3.85 2.04 2.91 -1.54 -1.14 1.95 -1.00 -0.15 -1.87 -2.19 3.20 -1.28 -0.15 -1.87
Golgi -2.04 -1.51 -5.84 0.59 -5.81 -0.22 2.05 -1.40 -1.35 -1.61 -1.99 1.52 -1.56 -1.12 -1.66
Lipid Particles -1.81 -2.86 -4.75 1.54 0.41 1.10 1.15 1.00 -0.96 -1.46 0.08 1.10 0.78 1.20 -1.33
Mitochondria -3.58 -11.71 -8.44 -6.12 -5.81 -0.91 -9.79 -12.60 -2.55 -6.38 -2.23 -13.52 -15.61 -4.27 -8.08
Mitotic Spindle -1.45 0.82 -1.06 -0.74 -1.11 -0.01 -0.02 0.12 0.16 0.13 -1.33 -0.11 -0.97 0.06 -0.82
None -3.18 0.04 -2.22 2.71 -2.37 1.76 2.28 1.35 -0.86 -2.29 -0.55 2.46 0.36 1.03 -2.38
Nuclear Periphery 0.48 0.83 -1.77 -1.80 -1.82 -2.44 -1.25 -3.84 -2.59 -1.43 -2.24 -1.21 -4.25 -3.52 -1.97
Nuclear Periphery Foci -2.01 1.10 -1.40 1.45 -1.96 -0.14 1.63 1.13 0.84 -1.87 -0.90 1.80 0.52 1.15 -2.05
Nucleolus -9.01 -2.85 -10.79 -9.53 -10.20 1.56 2.21 -10.41 -12.25 -12.53 -5.99 -2.38 -17.45 -14.63 -15.58
Nucleus 9.20 4.96 12.34 10.36 11.12 0.68 -1.53 12.22 12.31 14.66 8.07 3.64 20.38 15.00 17.72
Peroxisomes -2.95 -4.22 -6.16 -5.23 -4.95 2.65 2.02 -0.36 -6.82 -5.28 -0.83 -0.83 -6.44 -5.31 -6.54
Vacuole -2.27 -2.54 -4.73 -1.57 -1.04 -2.57 1.68 -1.21 1.30 -2.30 -3.41 1.13 -1.88 0.89 -2.28
Vacuole Periphery -2.88 0.42 -6.95 -1.88 -7.92 -2.20 -1.21 -3.72 -1.24 -3.29 -3.15 -1.20 -4.09 -1.62 -3.68
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-5

Alb1

Alb1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Alb1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available