Standard name
Human Ortholog
Description Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Bud – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Bud Neck – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.13 – 0 0 0 0
Bud Site – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Cytoplasm – – 0 0.06 0 0 0 0 0 0 0 0 0.05 0.1 0.15 0.09 0.11 0.06 0.25 – 0 0 0 0
Endoplasmic Reticulum – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Endosome – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Golgi – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Mitochondria – – 0 0 0.05 0.24 0.36 0.17 0.27 0.32 0.39 0.32 0 0 0 0 0 0 0.48 – 0 0 0 0
Nucleus – – 0.97 0.92 0.95 0.88 0.85 0.86 0.85 0.81 0.81 0.79 0.94 0.88 0.82 0.86 0.84 0.85 0 – 0.91 0.94 0.87 0.8
Nuclear Periphery – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Nucleolus – – 0 0 0 0 0.06 0.08 0.1 0.09 0.15 0.13 0 0 0 0 0 0 0.11 – 0 0 0 0
Peroxisomes – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
SpindlePole – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Vac/Vac Membrane – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0 – 0 0 0.08 0.12
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Bud – – 0 0 2 1 6 5 3 6 0 6 0 0 1 0 0 0 0 – 1 1 1 3
Bud Neck – – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Bud Site – – 2 1 1 4 15 16 11 12 18 27 0 0 0 0 0 0 – – – – – –
Cell Periphery – – 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0
Cytoplasm – – 5 18 10 14 17 30 11 9 6 6 16 42 78 15 22 8 0 – 2 0 3 4
Endoplasmic Reticulum – – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 5 3 0 – 0 0 0 0
Endosome – – 0 0 0 0 0 0 0 0 0 1 0 1 1 1 0 0 0 – 3 0 3 4
Golgi – – 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 – 3 0 2 0
Mitochondria – – 16 9 20 134 322 160 132 224 227 250 1 2 1 2 8 3 1 – 2 0 1 2
Nucleus – – 385 277 397 495 755 804 411 561 473 618 276 381 417 143 168 121 0 – 367 181 370 329
Nuclear Periphery – – 4 3 3 8 9 29 6 12 9 24 3 10 2 1 5 0 0 – 0 0 1 2
Nucleolus – – 4 4 5 22 57 72 49 64 86 98 0 0 3 0 4 6 0 – 1 0 3 9
Peroxisomes – – 1 1 0 0 0 0 0 0 0 0 1 1 0 1 0 1 0 – 0 0 0 0
SpindlePole – – 1 0 0 0 0 0 0 0 0 0 0 6 3 0 1 3 0 – 1 0 0 2
Vac/Vac Membrane – – 0 2 5 2 13 12 1 12 3 5 0 1 6 9 7 7 0 – 15 4 31 47
Unique Cell Count 396 301 420 565 884 940 484 694 583 780 294 431 506 166 201 143 4 402 192 425 410
Labelled Cell Count 419 315 443 680 1194 1128 624 900 822 1035 297 446 513 172 220 152 4 402 192 425 410


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) – – 6.6 6.6 5.9 4.8 4.6 4.8 4.7 4.6 4.3 4.4 8.0 7.4 7.3 10.2 9.7 11.0 7.7 8.3 8.7
Std Deviation (1e-4) – – 1.6 1.9 1.6 1.1 1.0 1.3 1.5 1.2 1.0 0.9 1.4 1.5 1.6 2.6 2.6 3.8 1.3 1.5 1.6
Intensity Change (Log2) – – – 0.01 -0.16 -0.45 -0.52 -0.44 -0.47 -0.51 -0.62 -0.59 0.28 0.17 0.15 0.64 0.56 0.74 0.23 0.33 0.4


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.5 1.2 1.3 0.8 2.0 1.1 0 0 0 3.2 5.3 7.3 4.5 5.4 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.7 0.5 0 0 0 0 0 0 0 -3.1 -3.5 -4.2 -1.7 0 -1.1
Nucleus -3.1 -1.9 -5.3 -6.3 -6.2 -6.2 -7.7 -7.5 -8.2 -2.2 -4.8 -7.0 -5.0 -6.0 -5.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 1.5 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.4151 4.7705 4.3147 4.0037 3.7646 4.2638 3.9186 4.6337 4.4779 3.884 3.5475 4.1039 3.0769 3.2733 2.8789 2.2792 2.4817 2.6446
Actin 0.006 0 0.0043 0.0007 0.036 0.0018 0.0273 0 0.014 0.0038 0.0135 0.0107 0.0303 0 0.004 0.0355 0.0052 0.0001
Bud 0.0001 0.0001 0.0001 0.0001 0.0002 0 0.0007 0 0.0009 0.0003 0.0014 0.0001 0.0004 0 0.0001 0.0001 0.0021 0
Bud Neck 0.0002 0 0.0002 0.0001 0.0006 0.0003 0.004 0 0.0004 0.0038 0.001 0.0007 0.001 0 0.0001 0.0002 0.0028 0.0004
Bud Periphery 0.0002 0.0003 0.0002 0.0004 0.0004 0.0001 0.0015 0 0.0018 0.0004 0.0029 0.0002 0.0007 0 0.0002 0.0002 0.0055 0
Bud Site 0.0001 0.0001 0.0007 0.0002 0.0005 0 0.008 0 0.0021 0.0045 0.0053 0.0002 0.0014 0 0.0001 0.0004 0.0053 0
Cell Periphery 0 0.0001 0.0002 0.0003 0.0001 0 0.0009 0 0.0003 0.0002 0.0004 0 0.0002 0 0 0 0.0016 0
Cytoplasm 0.0006 0 0.0001 0.0002 0.0013 0 0.0036 0.0001 0.0003 0.0005 0.0043 0.0003 0.0064 0 0.0001 0.0001 0.0028 0.0003
Cytoplasmic Foci 0.0086 0 0.0007 0.0004 0.0017 0.0002 0.0103 0.0002 0.0016 0.0246 0.007 0.0019 0.0062 0 0.0022 0.0181 0.0075 0.0004
Eisosomes 0.0001 0 0 0.0001 0.001 0 0.0005 0 0.0002 0.0001 0.0002 0.0001 0.0002 0 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0013 0 0.0002 0.0012 0.0012 0.0002 0.0045 0.0004 0.0015 0.0029 0.0037 0.0009 0.0042 0 0.0001 0.0001 0.0018 0.0001
Endosome 0.0049 0 0.0015 0.0021 0.0047 0.0014 0.0154 0.0043 0.0036 0.0262 0.0409 0.0098 0.0126 0 0.0013 0.0046 0.0147 0.0005
Golgi 0.0042 0 0.0008 0.0008 0.0034 0.0011 0.0041 0.0006 0.0026 0.013 0.0123 0.0025 0.0041 0 0.0011 0.0039 0.0017 0
Lipid Particles 0.0071 0 0.002 0.0093 0.0027 0.0007 0.0127 0.0002 0.0071 0.0117 0.0244 0.0033 0.0052 0 0.0045 0.0477 0.0037 0.0001
Mitochondria 0.0015 0.0064 0.0006 0.0119 0.0026 0.0005 0.0162 0.0002 0.0069 0.0314 0.019 0.0112 0.0067 0.0001 0.0012 0.0012 0.0064 0.0002
None 0.0004 0 0.0002 0.0004 0.0176 0 0.0036 0 0.0003 0.0002 0.0038 0.0004 0.0031 0 0.0002 0.0002 0.0025 0.0002
Nuclear Periphery 0.0087 0.0008 0.0058 0.0075 0.0066 0.0016 0.0373 0.0021 0.0045 0.0127 0.0289 0.0036 0.0134 0.0007 0.0007 0.0002 0.0195 0.0052
Nucleolus 0.009 0.0068 0.0029 0.0147 0.068 0.0198 0.0144 0.005 0.0035 0.0047 0.0555 0.0147 0.0067 0.0064 0.0035 0.0025 0.0315 0.0185
Nucleus 0.9397 0.9846 0.9764 0.9432 0.8436 0.9714 0.8122 0.9861 0.9404 0.8362 0.7359 0.9346 0.885 0.9927 0.9762 0.8611 0.8577 0.9694
Peroxisomes 0.0047 0 0.0005 0.0002 0.0017 0.0001 0.0046 0 0.0067 0.0155 0.005 0.0013 0.0039 0 0.0026 0.0229 0.0037 0
Punctate Nuclear 0.0015 0.0003 0.0018 0.0004 0.005 0.0004 0.0065 0.0001 0.0003 0.0005 0.0081 0.0017 0.0056 0.0001 0.0013 0.0007 0.019 0.0041
Vacuole 0.0004 0.0002 0.0005 0.002 0.0004 0.0001 0.0062 0.0003 0.0007 0.003 0.0135 0.001 0.0015 0 0.0003 0.0001 0.0036 0.0002
Vacuole Periphery 0.0008 0.0002 0.0003 0.004 0.0009 0.0002 0.0055 0.0003 0.0007 0.0039 0.013 0.0008 0.0012 0 0.0003 0.0001 0.0012 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.072 28.2556 22.8729 19.4906 22.9742 13.402 19.9118 18.1136 18.7578 22.304
Translational Efficiency 1.9624 1.5677 1.5284 1.3564 1.4728 2.1141 1.8229 1.1445 1.0062 1.3609

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1884 978 477 1217 1618 1356 269 483 3502 2334 746 1700

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 856.87 865.16 1058.62 1064.12 797.96 887.92 1040.19 1102.12 829.65 878.38 1051.97 1074.92
Standard Deviation 114.73 158.12 133.47 183.41 107.64 120.50 132.61 160.48 115.31 137.98 133.45 178.02
Intensity Change Log 2 — 0.013891 0.305037 0.312513 — 0.154113 0.382459 0.465893 — 0.083209 0.342889 0.388510

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000202 0.000607 0.000775 0.000682 0.000189 0.000318 0.000600 0.000721 0.000196 0.000439 0.000712 0.000693
Bud Neck 0.003278 0.005742 0.013645 0.015071 0.002685 0.004285 0.004546 0.013246 0.003004 0.004895 0.010364 0.014552
Bud Site 0.000668 0.001757 0.001015 0.001323 0.000366 0.001168 0.000553 0.002016 0.000528 0.001415 0.000848 0.001520
Cell Periphery 0.000250 0.000289 0.000047 0.000077 0.000219 0.000143 0.000047 0.000083 0.000236 0.000204 0.000047 0.000078
Cytoplasm 0.000929 0.002508 0.000355 0.001164 0.001850 0.001554 0.000842 0.002850 0.001354 0.001954 0.000531 0.001643
Cytoplasmic Foci 0.000517 0.000631 0.000019 0.000463 0.000248 0.001154 0.000057 0.000029 0.000392 0.000935 0.000032 0.000339
Eisosomes 0.000023 0.000033 0.000042 0.000027 0.000020 0.000022 0.000035 0.000026 0.000022 0.000027 0.000040 0.000027
Endoplasmic Reticulum 0.007043 0.008362 0.004214 0.004756 0.006319 0.006841 0.005593 0.003758 0.006709 0.007478 0.004711 0.004472
Endosome 0.000590 0.001202 0.000099 0.000630 0.000247 0.000404 0.000121 0.000124 0.000432 0.000738 0.000107 0.000486
Golgi 0.000267 0.000403 0.000045 0.001234 0.000108 0.000228 0.000043 0.000057 0.000194 0.000301 0.000044 0.000899
Lipid Particles 0.000309 0.000546 0.000066 0.000052 0.000444 0.000161 0.000136 0.000041 0.000371 0.000322 0.000091 0.000049
Mitochondria 0.001861 0.000958 0.000982 0.002408 0.000550 0.001273 0.000578 0.001432 0.001256 0.001141 0.000836 0.002130
Mitotic Spindle 0.001279 0.002262 0.000137 0.002816 0.000574 0.001583 0.000120 0.006928 0.000954 0.001867 0.000131 0.003984
None 0.001323 0.003911 0.000825 0.001471 0.001992 0.002358 0.003460 0.003915 0.001632 0.003009 0.001776 0.002166
Nuclear Periphery 0.000546 0.000231 0.000191 0.000581 0.000326 0.000329 0.000200 0.000480 0.000444 0.000288 0.000195 0.000553
Nuclear Periphery Foci 0.000838 0.000413 0.000031 0.000310 0.000287 0.000120 0.000077 0.000067 0.000584 0.000243 0.000047 0.000241
Nucleolus 0.004759 0.007909 0.004590 0.004318 0.004651 0.005249 0.006610 0.004956 0.004709 0.006364 0.005318 0.004499
Nucleus 0.973148* 0.959880* 0.971413* 0.959250* 0.977618* 0.971481* 0.974963* 0.957939* 0.975214* 0.966620* 0.972693* 0.958877*
Peroxisomes 0.000745 0.000471 0.000278 0.000155 0.000495 0.000269 0.000220 0.000141 0.000629 0.000354 0.000257 0.000151
Vacuole 0.001050 0.001481 0.001145 0.002382 0.000741 0.000778 0.001134 0.001088 0.000907 0.001073 0.001141 0.002014
Vacuole Periphery 0.000373 0.000403 0.000084 0.000832 0.000072 0.000280 0.000067 0.000105 0.000234 0.000331 0.000078 0.000625

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.58 -12.66 -10.90 -1.36 1.57 -2.51 -8.17 -9.43 -7.71 -4.18 -5.21 -14.85 -14.21 -6.47 -1.01
Bud Neck -2.53 -7.89 -12.90 -8.61 -1.90 -2.49 -2.25 -6.71 -5.90 -5.45 -3.48 -8.11 -14.43 -11.65 -4.86
Bud Site -2.47 -2.10 -2.79 0.39 -1.08 -2.12 -2.11 -3.06 -1.53 -2.60 -2.97 -3.03 -4.57 -1.04 -2.74
Cell Periphery -0.59 4.47 3.83 4.12 -2.79 1.03 2.78 2.21 1.41 -1.35 0.64 5.01 4.19 3.78 -3.04
Cytoplasm -1.75 2.01 -0.70 1.49 -3.68 0.17 0.64 -0.79 -0.87 -1.11 -1.19 1.84 -0.73 0.45 -2.23
Cytoplasmic Foci -0.30 3.02 0.76 0.89 -1.84 -1.28 1.61 1.77 1.66 1.26 -1.23 3.44 0.89 1.57 -1.77
Eisosomes -3.35 -8.03 -2.36 1.95 6.98 -0.57 -5.58 -4.59 -4.54 1.76 -2.67 -9.98 -4.56 -1.34 6.91
Endoplasmic Reticulum -1.88 5.18 4.81 5.65 -0.29 -0.95 0.94 3.29 4.57 2.10 -1.78 4.64 5.60 7.04 1.00
Endosome -0.95 2.81 0.19 0.97 -1.37 -1.25 1.62 0.63 1.96 -2.30 -1.06 3.20 -0.02 0.85 -1.46
Golgi -0.61 2.18 -0.90 -0.69 -1.20 -0.57 1.03 0.27 0.71 -3.84 -0.70 2.39 -0.95 -0.74 -1.22
Lipid Particles -0.81 2.27 2.43 1.61 0.98 0.84 0.91 0.99 1.14 0.88 0.18 1.62 1.77 1.90 1.59
Mitochondria 1.33 1.15 -0.97 -4.36 -4.30 -1.67 -0.26 -5.32 -1.52 -7.29 0.26 0.92 -2.59 -3.67 -5.87
Mitotic Spindle -0.68 1.85 -1.84 -0.86 -2.78 -1.13 0.62 -2.55 -2.22 -2.65 -1.14 1.90 -3.23 -2.34 -3.82
None -4.09 1.59 -1.05 3.26 -2.29 -0.50 -1.26 -0.93 -0.68 -0.01 -2.97 -0.35 -1.05 1.39 -0.67
Nuclear Periphery 1.76 1.64 -1.01 -7.58 -6.92 -0.12 2.55 -5.17 -5.11 -6.40 1.54 2.08 -3.08 -8.35 -9.40
Nuclear Periphery Foci 1.23 2.41 1.19 0.03 -1.71 1.29 1.61 0.19 -0.94 -1.22 1.77 2.81 0.99 -0.70 -1.95
Nucleolus -2.44 -0.17 -1.37 1.18 -1.26 -0.44 -1.23 -0.78 -0.56 0.17 -2.10 -1.00 -1.57 0.16 -0.75
Nucleus 3.05 1.53 5.20 1.54 4.02 1.94 1.07 5.21 4.09 4.50 3.27 2.12 7.64 4.58 6.01
Peroxisomes 0.56 1.07 1.35 2.12 3.61 0.89 1.02 1.14 1.23 1.29 1.08 1.45 1.77 2.49 3.76
Vacuole -1.01 -0.99 -2.30 -1.31 -0.83 -0.66 -1.65 -2.95 -2.75 -2.37 -1.04 -1.45 -3.58 -2.92 -1.77
Vacuole Periphery -0.26 2.05 -0.78 -0.67 -1.49 -1.95 0.02 -2.83 1.38 -2.98 -0.96 1.99 -1.03 -0.67 -1.55
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of tRNA (1-methyladenosine) methyltransferase; required, along with Gcd10p, for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Gcd14

Gcd14


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gcd14-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available