Standard name
Human Ortholog
Description Histone H3 acetylase with a role in transcriptional regulation; sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near TATA box; involved in S phase-specific acetylation of H3K56 at histone promoters, which is required for recruitment of SWI/SNF nucleosome remodeling complex and subsequent transcription
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.07 0.12 0.17 0.27 0.23 0.21 0.24 – 0.24 0.18 0.17 0.12 0.12 0.28 0.33 0.22 0.15 0.16 0.05 0 0.05 0.05 0.11 0.07
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0.12 0 0.14 0.08 0.06 – 0.07 0.05 0 0 0 0 0 0.05 0.08 0.11 0.06 0.05 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.3 0 0 0 0.06 0.26 0.28 – 0.49 0.5 0.68 0.65 0 0 0 0.06 0 0 0 0 0 0 0.06 0.05
Nucleus 0.61 0.68 0.53 0.57 0.4 0.34 0.39 – 0.29 0.37 0.33 0.39 0.88 0.64 0.56 0.54 0.56 0.57 0.5 0.57 0.49 0.56 0.4 0.35
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.06 0.05 0.05 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.05 0 0.07 – 0 0 0 0.06 0 0 0 0 0 0 0.12 0.07 0.06 0.07 0.09 0.12
Vac/Vac Membrane 0.19 0.2 0.24 0.08 0.24 0.17 0.13 – 0.05 0.11 0.06 0.06 0.05 0 0.09 0.2 0.22 0.22 0.12 0.14 0.17 0.18 0.19 0.2
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 2 1 0 0 0
Bud 0 0 0 0 0 3 3 – 2 5 6 4 0 0 0 0 0 1 2 10 2 1 6 6
Bud Neck 0 0 1 1 1 2 1 – 0 4 0 0 0 1 0 0 0 0 0 1 3 1 2 6
Bud Site 0 1 0 1 1 2 2 – 5 5 5 8 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Cytoplasm 10 35 25 32 37 47 45 – 41 33 35 19 5 51 59 79 40 48 8 10 9 5 25 15
Endoplasmic Reticulum 2 2 0 1 0 0 0 – 0 0 0 0 0 1 2 19 15 15 0 0 1 0 0 0
Endosome 3 9 17 2 23 18 11 – 11 10 1 1 0 3 5 18 23 32 11 18 5 0 7 6
Golgi 1 1 2 1 0 1 0 – 0 0 0 0 0 1 0 4 3 0 1 2 1 0 0 3
Mitochondria 42 11 3 5 9 57 54 – 83 93 143 106 0 0 0 21 6 10 6 7 8 2 15 10
Nucleus 86 206 76 67 64 74 75 – 49 69 70 64 37 116 101 192 152 169 94 199 97 62 94 75
Nuclear Periphery 0 2 0 0 0 0 0 – 0 0 0 0 0 0 0 0 1 0 0 3 0 0 0 1
Nucleolus 0 1 1 1 1 3 1 – 2 2 1 2 1 0 0 5 1 6 11 17 10 3 9 9
Peroxisomes 0 0 0 0 0 0 2 – 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 1 8 6 5 8 7 14 – 6 6 3 10 1 3 7 2 7 2 23 24 12 8 21 25
Vac/Vac Membrane 27 60 34 9 38 38 24 – 9 20 12 10 2 7 17 71 60 65 22 48 34 20 45 43
Unique Cell Count 142 302 143 118 161 219 191 168 187 210 163 42 180 181 358 273 297 191 353 198 112 240 215
Labelled Cell Count 172 336 165 125 182 252 232 208 247 276 224 46 183 191 411 308 350 191 353 198 112 240 215


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 5.3 6.2 6.4 6.4 5.4 5.1 – 4.6 4.5 4.0 4.2 5.1 6.1 5.7 8.1 8.0 7.7 4.9 5.6 5.8
Std Deviation (1e-4) 0.6 1.0 1.5 2.1 2.0 1.7 1.5 – 1.9 1.5 1.4 1.6 0.6 1.3 1.1 1.9 2.1 1.8 0.6 1.3 1.3
Intensity Change (Log2) – – – 0.04 0.04 -0.22 -0.29 – -0.44 -0.48 -0.65 -0.57 -0.29 -0.04 -0.13 0.37 0.36 0.3 -0.36 -0.16 -0.11

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.9 1.2 0.9 1.4 – 1.5 0 -0.2 -1.4 -0.9 2.3 3.1 1.1 -0.8 -0.3
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 2.8 2.9 0
Endosome -3.2 0.6 -1.2 -2.0 – 0 0 0 0 0 -3.8 -3.2 -2.7 -1.1 -0.3
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 1.6 6.0 6.3 – 0 0 0 0 0 0 0 1.8 0 0
Nucleus 0.6 -2.3 -3.7 -2.5 – -4.3 -2.9 -3.7 -2.4 4.1 2.1 0.5 0.1 0.5 0.7
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0.3 -0.5 1.2 – 0 0 0 0 0 0 -0.1 0 0 0
Vacuole -3.5 0 -1.5 -2.7 – -4.7 -3.2 -4.9 -4.4 -2.7 -5.3 -3.5 -1.0 -0.4 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.0792 0.3073 0.0075 -0.6248 -0.6182 -0.0691 0.8309 0.9194 1.0264 1.0327 1.1901 0.8138 0.3466 0.5951 0.3789 0.4164 1.1229 0.3521
Actin 0.0236 0.0002 0.0032 0.0395 0.024 0.0029 0.0104 0.0002 0.017 0.001 0.0079 0.0024 0.0154 0.0014 0.0106 0.0002 0.0142 0.0066
Bud 0.0005 0.0001 0.0001 0.0001 0.0005 0.0001 0.0006 0.0001 0.0003 0.0016 0.0005 0.0003 0.0002 0.0002 0.0009 0 0.0002 0.0001
Bud Neck 0.001 0.0005 0.0005 0.001 0.0016 0.0028 0.003 0.0006 0.0009 0.0026 0.0013 0.0027 0.003 0.0004 0.0003 0.0005 0.0016 0.0027
Bud Periphery 0.0011 0.0001 0.0001 0.0001 0.0014 0.0002 0.0016 0.0001 0.0007 0.0049 0.0022 0.001 0.0004 0.0004 0.0002 0 0.0002 0.0002
Bud Site 0.0018 0.001 0.0006 0.0013 0.0007 0.0001 0.0026 0.0008 0.0061 0.0027 0.0004 0.0002 0.0009 0.0003 0.0005 0.0001 0.0004 0.0003
Cell Periphery 0.0003 0 0 0 0.0003 0 0.0003 0 0.0002 0.0008 0.0002 0 0.0002 0 0 0 0.0001 0
Cytoplasm 0.0153 0.0128 0.019 0.0015 0.0026 0.0081 0.0127 0.0136 0.013 0.0038 0.0119 0.0079 0.0075 0.0144 0.0063 0.0092 0.0242 0.0053
Cytoplasmic Foci 0.0265 0.0003 0.005 0.0049 0.0072 0.0021 0.0182 0.0008 0.0085 0.0025 0.0087 0.0015 0.0058 0.0002 0.0027 0.0001 0.0064 0.0012
Eisosomes 0.0004 0 0.0005 0.0001 0.0054 0 0.0002 0 0.0009 0 0.0002 0 0.0001 0 0 0 0.0002 0.0001
Endoplasmic Reticulum 0.0049 0.0068 0.0013 0.0001 0.0015 0.001 0.0024 0.0008 0.0013 0.0024 0.0042 0.0007 0.0022 0.001 0.0002 0.0004 0.0037 0.0006
Endosome 0.0431 0.003 0.0055 0.0005 0.0241 0.0026 0.0292 0.0013 0.0145 0.0187 0.0414 0.0044 0.0092 0.0005 0.0006 0.0005 0.0207 0.0038
Golgi 0.0086 0 0.0051 0.0017 0.016 0.0006 0.0092 0.0001 0.0041 0.0033 0.0191 0.0042 0.0014 0.0001 0.0005 0 0.0053 0.0016
Lipid Particles 0.0417 0.0001 0.0046 0.0022 0.089 0.0059 0.0301 0.0001 0.0102 0.0096 0.0296 0.0032 0.0045 0 0.0031 0 0.0149 0.0018
Mitochondria 0.0216 0.0003 0.0022 0.0006 0.0813 0.001 0.0112 0.0003 0.0271 0.0115 0.0486 0.0035 0.0017 0.0015 0.0004 0.0002 0.0021 0.0017
None 0.017 0.0155 0.0331 0.0002 0.0494 0.0248 0.0155 0.0242 0.0086 0.0013 0.0237 0.0128 0.0043 0.0049 0.0137 0.0477 0.0613 0.0033
Nuclear Periphery 0.0304 0.0377 0.0225 0.0087 0.0305 0.0158 0.0171 0.0119 0.0177 0.0095 0.0187 0.006 0.0245 0.0103 0.0103 0.0102 0.0267 0.0069
Nucleolus 0.0074 0.0144 0.01 0.0043 0.0363 0.0138 0.0111 0.012 0.0096 0.014 0.0135 0.0257 0.0102 0.0114 0.0108 0.0087 0.0133 0.0173
Nucleus 0.6866 0.8651 0.8485 0.8831 0.5374 0.8757 0.783 0.8988 0.8227 0.8596 0.6763 0.8918 0.8659 0.9237 0.9105 0.9118 0.7699 0.9116
Peroxisomes 0.0284 0 0.002 0.0151 0.0119 0.0018 0.0174 0.0001 0.0071 0.0019 0.0588 0.0008 0.0085 0.0002 0.0051 0 0.0048 0.0008
Punctate Nuclear 0.028 0.0397 0.035 0.0349 0.0721 0.0397 0.0193 0.033 0.0271 0.0236 0.028 0.0301 0.0313 0.0285 0.023 0.0104 0.0267 0.0337
Vacuole 0.0084 0.0017 0.0008 0 0.0039 0.0006 0.0035 0.0008 0.0015 0.0201 0.0021 0.0005 0.0019 0.0004 0.0002 0.0001 0.0019 0.0004
Vacuole Periphery 0.0033 0.0006 0.0005 0.0001 0.003 0.0003 0.0014 0.0003 0.0008 0.0045 0.0027 0.0004 0.0009 0.0002 0.0001 0.0001 0.0011 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.4759 4.6164 8.3737 11.7019 10.7872 12.043 12.5768 16.2768 10.5976 12.8429
Translational Efficiency 0.7447 1.4095 0.679 0.5333 0.5697 0.6684 0.5239 0.3537 0.6803 0.6768

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1969 1337 851 1854 1530 1501 1558 97 3499 2838 2409 1951

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 582.18 757.05 867.71 909.05 681.98 726.32 898.64 976.69 625.82 740.80 887.71 912.41
Standard Deviation 65.72 102.09 127.34 130.48 78.76 97.78 108.47 123.47 87.14 101.01 116.43 130.97
Intensity Change Log 2 — 0.378923 0.575748 0.642894 — 0.090876 0.398014 0.518171 — 0.230699 0.482592 0.576952

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000051 0.000762 0.000816 0.000806 0.000112 0.000466 0.000713 0.002126 0.000078 0.000605 0.000749 0.000871
Bud Neck 0.007736 0.009382 0.009598 0.031600 0.003701 0.007396 0.011137 0.027156 0.005972 0.008331 0.010593 0.031379
Bud Site 0.005227 0.004391 0.004310 0.013401 0.001025 0.004038 0.001619 0.024020 0.003390 0.004205 0.002570 0.013929
Cell Periphery 0.000317 0.000160 0.000079 0.000166 0.000102 0.000131 0.000103 0.000207 0.000223 0.000145 0.000095 0.000168
Cytoplasm 0.276379 0.130654 0.017091 0.033069 0.160327 0.116914 0.012411 0.032990 0.225633 0.123387 0.014064 0.033065
Cytoplasmic Foci 0.070033 0.033107 0.000549 0.002358 0.027707 0.029225 0.000516 0.004016 0.051525 0.031054 0.000528 0.002441
Eisosomes 0.000103 0.000063 0.000029 0.000026 0.000040 0.000055 0.000028 0.000038 0.000075 0.000059 0.000029 0.000026
Endoplasmic Reticulum 0.001001 0.004951 0.006941 0.005745 0.001729 0.003595 0.006158 0.006078 0.001319 0.004234 0.006435 0.005761
Endosome 0.001442 0.003635 0.000590 0.005563 0.001304 0.005128 0.000976 0.008341 0.001382 0.004425 0.000840 0.005701
Golgi 0.000436 0.001537 0.000085 0.005386 0.000237 0.002240 0.000171 0.000667 0.000349 0.001909 0.000141 0.005151
Lipid Particles 0.011856 0.008264 0.000433 0.000294 0.004992 0.008498 0.000489 0.000765 0.008854 0.008388 0.000469 0.000317
Mitochondria 0.003491 0.010906 0.001304 0.007689 0.005096 0.014713 0.001283 0.004039 0.004193 0.012919 0.001291 0.007508
Mitotic Spindle 0.000238 0.013989 0.001491 0.056603 0.002252 0.023997 0.002305 0.123647 0.001118 0.019282 0.002018 0.059936
None 0.034967 0.014360 0.003680 0.009278 0.015077 0.013933 0.005055 0.015135 0.026270 0.014134 0.004569 0.009569
Nuclear Periphery 0.001862 0.003824 0.001008 0.003575 0.003942 0.004113 0.001214 0.001640 0.002772 0.003977 0.001141 0.003479
Nuclear Periphery Foci 0.001830 0.005256 0.000432 0.001397 0.003165 0.002797 0.000594 0.000666 0.002414 0.003955 0.000537 0.001360
Nucleolus 0.014253 0.018671 0.004491 0.003925 0.015305 0.017274 0.006264 0.003012 0.014713 0.017932 0.005638 0.003880
Nucleus 0.562001 0.721353 0.940853 0.791773 0.748841 0.727482 0.944250 0.723226 0.643700 0.724595 0.943050 0.788365
Peroxisomes 0.002566 0.005436 0.000245 0.000427 0.001796 0.006236 0.000231 0.002715 0.002229 0.005859 0.000236 0.000540
Vacuole 0.003870 0.008438 0.005741 0.020371 0.002988 0.010258 0.004007 0.018378 0.003485 0.009401 0.004620 0.020272
Vacuole Periphery 0.000340 0.000861 0.000234 0.006551 0.000262 0.001511 0.000475 0.001137 0.000306 0.001205 0.000390 0.006282

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.21 -13.28 -20.38 -0.85 1.00 -7.19 -16.41 -5.25 -4.44 -3.42 -11.74 -21.74 -19.60 -5.38 -1.13
Bud Neck -2.15 -4.03 -13.98 -12.11 -9.33 -4.41 -11.37 -4.40 -3.58 -1.67 -3.72 -10.00 -16.35 -14.24 -9.66
Bud Site 0.13 0.36 -3.16 -3.40 -3.42 -3.80 -3.93 -2.66 -1.96 -2.27 -1.47 -0.21 -5.70 -4.59 -6.01
Cell Periphery 6.45 12.42 9.84 2.38 -4.88 -2.63 0.63 -2.33 -1.12 -2.56 5.33 11.42 7.47 1.88 -4.50
Cytoplasm 18.90 45.06 42.49 18.71 -6.04 5.66 27.45 20.30 15.68 -1.04 18.71 51.83 45.24 25.09 -8.39
Cytoplasmic Foci 10.12 25.76 25.55 14.26 -2.26 0.27 15.01 14.50 14.08 -0.83 8.90 29.30 28.95 20.15 -2.44
Eisosomes 5.06 11.44 12.60 9.96 0.50 -3.35 4.53 -2.47 -0.99 -4.09 3.39 12.64 12.29 11.19 -0.90
Endoplasmic Reticulum -13.31 -15.26 -22.74 -6.24 1.03 -5.90 -17.20 -6.08 -5.05 -3.00 -13.73 -23.88 -22.73 -10.42 -0.61
Endosome -4.16 6.22 -2.16 2.29 -4.34 -5.57 3.55 -0.99 1.99 -1.73 -6.98 5.31 -2.17 3.99 -4.18
Golgi -2.97 7.75 -2.17 -0.37 -2.72 -3.70 3.30 -0.00 3.67 -1.92 -4.68 7.11 -2.27 0.18 -2.70
Lipid Particles 4.28 16.48 16.64 11.92 1.06 -3.50 10.83 8.82 9.23 -2.16 1.28 19.40 19.54 15.24 0.06
Mitochondria -5.24 7.93 -2.93 3.74 -7.18 -4.43 3.09 1.78 6.34 -3.40 -6.78 5.25 -1.29 6.06 -7.25
Mitotic Spindle -7.38 -3.47 -11.42 -4.70 -10.52 -6.85 -0.47 -2.53 -1.29 -2.50 -10.04 -2.65 -11.27 -4.32 -10.65
None 8.77 15.39 12.99 4.64 -6.39 0.90 8.57 3.94 3.23 -1.11 8.27 17.02 13.62 6.08 -5.26
Nuclear Periphery -6.08 2.66 -8.64 -1.18 -11.69 -0.58 4.49 1.43 2.07 -2.79 -3.69 4.96 -4.77 -0.54 -11.65
Nuclear Periphery Foci -3.23 2.30 3.25 5.17 0.72 0.90 4.77 4.15 3.91 -1.05 -2.00 5.53 5.09 6.35 -0.67
Nucleolus -0.81 8.50 9.53 9.38 0.75 0.25 8.07 9.48 9.35 2.50 -0.40 11.54 12.67 12.54 1.35
Nucleus -13.96 -46.85 -30.10 -12.16 14.56 1.86 -25.77 -2.95 -3.63 4.26 -9.91 -52.21 -24.91 -14.27 17.02
Peroxisomes -4.91 9.97 10.17 9.51 0.89 -4.85 6.44 3.51 6.78 -1.60 -6.75 11.70 11.49 11.96 -0.34
Vacuole -6.11 -4.09 -11.04 -7.06 -8.04 -6.16 -4.04 -3.38 -2.65 -3.03 -8.43 -5.32 -11.87 -7.37 -9.30
Vacuole Periphery -4.16 1.08 -3.65 -2.70 -3.84 -4.76 -0.40 -1.15 3.80 -0.38 -5.92 0.01 -3.73 -1.99 -3.67
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Histone H3 acetylase with a role in transcriptional regulation; sequence-specific activator of histone genes, binds specifically and cooperatively to pairs of UAS elements in core histone promoters, functions at or near TATA box; involved in S phase-specific acetylation of H3K56 at histone promoters, which is required for recruitment of SWI/SNF nucleosome remodeling complex and subsequent transcription
Localization
Cell Percentages nucleus (72%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Spt10

Spt10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Spt10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available