Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0.1 – 0.14 0.12 0.11 0.11 – 0.1 0.1 0.08 0.07 – 0.05 0 0 0 0 0 0 0 0 0 0
Bud 0 0 – 0 0 0 0.07 – 0.09 0.09 0.09 0.06 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.1 0.34 – 0.05 0.09 0.11 0.07 – 0 0.08 0.06 0.07 – 0.08 0.41 0.1 0.14 0.1 0 0 0 0.05 0 0
Endoplasmic Reticulum 0 0.08 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0.15 0.09 – 0.42 0.38 0.28 0.39 – 0.21 0.25 0.11 0.25 – 0.27 0.34 0.09 0.09 0.12 0.32 0.25 0.25 0.11 0.19 0.26
Golgi 0.08 0.19 – 0.34 0.3 0.22 0.23 – 0.17 0.25 0.07 0.11 – 0.35 0 0.1 0.19 0.19 0.29 0.37 0.1 0.3 0.4 0.36
Mitochondria 0.5 0.09 – 0.16 0.05 0.27 0.23 – 0.56 0.32 0.74 0.45 – 0.13 0 0.05 0 0.07 0.06 0.05 0.05 0.17 0.09 0.08
Nucleus 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 – 0 0 0.05 0 – 0.07 0 0.06 0.06 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 – 0.1 0.1 0.07 0.12 – 0.1 0.14 0 0.08 – 0.06 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.43 0.36 – 0.17 0.18 0.11 0.08 – 0.09 0.09 0.05 0.1 – 0.32 0.39 0.82 0.77 0.75 0.28 0.28 0.49 0.29 0.27 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 10 – 22 20 20 37 – 19 26 14 15 – 3 1 7 4 7 0 1 0 0 0 0
Bud 1 0 – 3 3 6 24 – 17 23 16 12 – 0 2 0 1 2 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 2 – 1 0 4 2 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 – 2 0 1 3 – 1 0 0 2 – 0 0 1 0 1 0 0 0 0 0 0
Cytoplasm 13 33 – 8 15 20 22 – 7 21 10 15 – 5 51 28 41 23 1 2 0 1 0 2
Endoplasmic Reticulum 5 8 – 2 7 7 3 – 3 2 3 6 – 2 1 10 8 12 1 0 0 0 0 0
Endosome 19 9 – 66 62 51 126 – 42 67 19 55 – 17 42 25 27 27 47 31 12 2 16 20
Golgi 11 19 – 53 50 40 75 – 33 67 13 23 – 22 3 28 54 42 43 47 5 7 34 28
Mitochondria 65 9 – 25 9 50 74 – 110 86 131 97 – 8 3 15 13 15 9 6 2 4 7 6
Nucleus 1 0 – 2 0 0 2 – 1 1 0 1 – 2 1 9 3 3 0 0 0 1 1 2
Nuclear Periphery 0 0 – 0 0 0 1 – 0 0 0 0 – 0 0 0 0 1 1 0 0 0 0 0
Nucleolus 7 0 – 2 1 9 9 – 14 8 10 12 – 2 0 1 2 2 0 0 0 0 0 0
Peroxisomes 0 0 – 1 7 4 11 – 1 11 2 4 – 0 1 0 0 0 2 1 1 0 0 0
SpindlePole 1 2 – 16 16 13 40 – 19 37 7 18 – 4 4 1 1 3 0 0 0 0 0 0
Vac/Vac Membrane 56 35 – 27 30 20 26 – 18 24 9 22 – 20 48 233 222 168 41 36 24 7 23 14
Unique Cell Count 130 98 157 164 184 322 197 267 176 217 63 124 283 289 223 148 129 51 25 85 80
Labelled Cell Count 179 126 229 220 241 455 286 373 238 284 85 157 358 376 306 148 129 51 25 85 80


Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.6 8.5 – 8.9 10.2 8.6 8.8 – 7.3 7.9 6.7 7.3 – 9.0 7.8 12.4 12.4 12.5 – 8.3 8.7
Std Deviation (1e-4) 1.1 1.3 – 1.3 1.7 1.3 1.4 – 1.0 1.1 1.1 1.1 – 1.3 1.6 2.7 2.7 2.8 – 1.7 1.2
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –

RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP700051015HU120HU160051015rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.7153 6.0023 5.2128 5.3189 4.3975 5.2804 4.2467 6.3393 6.0397 5.9792 4.5018 5.9706 3.2739 5.1398 4.8013 4.0406 3.9514 4.4959
Actin 0.0082 0.0086 0.0096 0.0052 0.011 0.0062 0.0161 0.0017 0.008 0.0001 0.0003 0.0102 0.0385 0.005 0.011 0.0013 0.0431 0.0023
Bud 0.0005 0.0032 0.0002 0.0003 0.0004 0.0001 0.0004 0.0001 0.0003 0 0.0002 0.0001 0.0003 0.0086 0.0001 0.0001 0.0002 0
Bud Neck 0.0003 0.0002 0.0008 0.0004 0.0008 0.0003 0.0006 0.0001 0.0015 0.0001 0.0002 0.0003 0.0005 0.0002 0.0002 0.0002 0.0005 0.0002
Bud Periphery 0.0002 0.0014 0.0003 0.0006 0.0003 0.0001 0.0005 0.0001 0.0004 0 0.0002 0.0002 0.0004 0.0033 0.0001 0.0001 0.0005 0
Bud Site 0.0006 0.0017 0.0006 0.0005 0.0007 0.0001 0.0029 0.0002 0.0012 0 0.0046 0.0002 0.0011 0.0077 0.0004 0.0003 0.001 0.0001
Cell Periphery 0.0003 0.0002 0.0002 0.0002 0.0001 0.0001 0.0003 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0002 0 0 0.0002 0
Cytoplasm 0.0037 0.0026 0.0015 0.0008 0.0095 0.001 0.008 0.0129 0.0024 0.0003 0.0011 0.0009 0.0038 0.0035 0.0028 0.0022 0.0015 0.0014
Cytoplasmic Foci 0.0812 0.1032 0.0753 0.0574 0.0972 0.0593 0.0786 0.0903 0.0646 0.0349 0.0597 0.0439 0.0798 0.0824 0.0826 0.0786 0.0654 0.0543
Eisosomes 0.0002 0 0.0001 0.0001 0 0 0.0003 0 0.0001 0 0 0.0002 0.0004 0 0.0001 0 0.0016 0
Endoplasmic Reticulum 0.0011 0.0007 0.0012 0.0007 0.002 0.0011 0.0025 0.0015 0.0011 0.0004 0.001 0.001 0.0024 0.0003 0.001 0.0024 0.0024 0.0005
Endosome 0.3145 0.3382 0.3038 0.3031 0.3007 0.268 0.3189 0.3774 0.3134 0.3682 0.3353 0.3524 0.2931 0.2604 0.2443 0.3057 0.3691 0.2913
Golgi 0.4944 0.4815 0.5323 0.5643 0.4739 0.5885 0.4393 0.4549 0.5381 0.5512 0.4844 0.4976 0.4794 0.6018 0.6133 0.4882 0.4637 0.606
Lipid Particles 0.0264 0.0177 0.0179 0.0168 0.0247 0.0151 0.0388 0.0138 0.018 0.0107 0.0453 0.0275 0.0255 0.0081 0.0055 0.0198 0.015 0.024
Mitochondria 0.0227 0.0133 0.0241 0.0233 0.0127 0.0264 0.027 0.0096 0.0177 0.0136 0.0229 0.0268 0.0294 0.0088 0.01 0.0041 0.0079 0.0072
None 0.0081 0.0008 0.0008 0.0016 0.002 0.0001 0.0075 0.0004 0.0006 0 0.0003 0.0002 0.0033 0.0002 0.0036 0.0016 0.0016 0
Nuclear Periphery 0.0042 0.0004 0.0013 0.0006 0.0128 0.0033 0.0111 0.0007 0.0015 0.0002 0.001 0.0024 0.0048 0.0001 0.0011 0.0042 0.0046 0.0002
Nucleolus 0.0024 0.0016 0.0003 0.0002 0.0008 0.0021 0.0013 0 0.002 0 0.0005 0.0001 0.0062 0.0001 0.0001 0.0002 0.0002 0
Nucleus 0.0021 0.0004 0.0004 0.0002 0.0099 0.0041 0.0082 0.0002 0.0012 0 0.0002 0.0001 0.0015 0.0001 0.0002 0.0005 0.0003 0
Peroxisomes 0.0114 0.011 0.014 0.0058 0.0188 0.0048 0.0175 0.0164 0.0149 0.0008 0.0076 0.0041 0.0194 0.0041 0.0116 0.0383 0.0095 0.0035
Punctate Nuclear 0.0032 0.0002 0.0026 0.0005 0.0066 0.0009 0.0048 0.0001 0.0017 0 0.0007 0.0002 0.0023 0.0001 0.0028 0.0033 0.0021 0.0001
Vacuole 0.0074 0.006 0.0059 0.0096 0.0054 0.0076 0.0063 0.0109 0.0052 0.0076 0.0154 0.0114 0.0037 0.0023 0.0034 0.0179 0.0033 0.0033
Vacuole Periphery 0.007 0.0072 0.0069 0.0078 0.0097 0.0109 0.0091 0.0086 0.0061 0.0116 0.019 0.02 0.0042 0.0026 0.0054 0.0309 0.0064 0.0056

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 67.9837 57.6926 39.4853 42.8386 58.4918 54.4821 48.2804 41.4732 38.8079 58.3627
Translational Efficiency 1.347 1.2222 1.2471 1.1307 1.1606 1.1309 1.1059 1.1275 1.0031 1.0204

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
101 1509 822 2071 2161 1770 2026 1120 2262 3279 2848 3191

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 899.19 860.18 1154.79 971.75 866.14 878.03 1078.47 956.77 867.62 869.82 1100.50 966.49
Standard Deviation 140.96 139.89 153.88 129.99 116.26 138.19 131.70 127.96 117.67 139.26 142.72 129.48
Intensity Change Log 2 — -0.063987 0.360933 0.111959 — 0.019670 0.316314 0.143572 — -0.022336 0.339213 0.127556

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.059435 0.002406 0.013812 0.010404 0.000611 0.002035 0.003819 0.006192 0.003238 0.002206 0.006703 0.008926
Bud Neck 0.003169 0.000380 0.000970 0.004064 0.000176 0.000134 0.000452 0.004260 0.000310 0.000247 0.000601 0.004133
Bud Site 0.022405 0.003126 0.012336 0.024937 0.001467 0.000997 0.002503 0.021310 0.002402 0.001977 0.005341 0.023664
Cell Periphery 0.000646 0.000083 0.000169 0.000102 0.000025 0.000047 0.000022 0.000059 0.000053 0.000064 0.000064 0.000087
Cytoplasm 0.011028 0.001180 0.014707 0.048968 0.002052 0.000806 0.002054 0.037790 0.002453 0.000978 0.005706 0.045045
Cytoplasmic Foci 0.235223 0.184161 0.314923 0.226656 0.215978 0.206527 0.310300 0.239147 0.216837 0.196234 0.311635 0.231040
Eisosomes 0.001089 0.000042 0.000055 0.000048 0.000020 0.000029 0.000019 0.000031 0.000068 0.000035 0.000030 0.000042
Endoplasmic Reticulum 0.008834 0.000409 0.027269 0.001103 0.000135 0.000212 0.000275 0.000424 0.000524 0.000303 0.008066 0.000865
Endosome 0.200691 0.308501 0.145543 0.287769 0.241725 0.287940 0.231722 0.324137 0.239893 0.297402 0.206849 0.300534
Golgi 0.358944 0.435458 0.351170 0.173363 0.482172 0.462589 0.398543 0.119517 0.476670 0.450103 0.384870 0.154464
Lipid Particles 0.023562 0.008528 0.026026 0.005233 0.002038 0.007026 0.003546 0.004228 0.002999 0.007717 0.010035 0.004880
Mitochondria 0.010077 0.010665 0.000309 0.006200 0.011539 0.009182 0.001830 0.004035 0.011474 0.009865 0.001391 0.005440
Mitotic Spindle 0.016293 0.000586 0.036105 0.025291 0.001904 0.000673 0.011691 0.037869 0.002546 0.000633 0.018737 0.029706
None 0.000092 0.000028 0.000028 0.000044 0.000026 0.000015 0.000006 0.000463 0.000029 0.000021 0.000012 0.000191
Nuclear Periphery 0.000234 0.000022 0.000440 0.000205 0.000029 0.000025 0.000136 0.000311 0.000038 0.000023 0.000224 0.000242
Nuclear Periphery Foci 0.001651 0.000207 0.017010 0.000716 0.000115 0.000162 0.001061 0.001680 0.000184 0.000183 0.005664 0.001054
Nucleolus 0.001272 0.000051 0.000017 0.000161 0.000044 0.000026 0.000010 0.000505 0.000099 0.000037 0.000012 0.000282
Nucleus 0.002131 0.000053 0.000206 0.001345 0.000060 0.000030 0.000017 0.001339 0.000152 0.000040 0.000071 0.001343
Peroxisomes 0.025124 0.006962 0.002808 0.026682 0.005261 0.007494 0.003716 0.021038 0.006148 0.007249 0.003454 0.024701
Vacuole 0.011290 0.024121 0.032762 0.148136 0.021814 0.008223 0.022810 0.166539 0.021344 0.015539 0.025683 0.154595
Vacuole Periphery 0.006809 0.013035 0.003332 0.008573 0.012808 0.005827 0.005468 0.009126 0.012540 0.009144 0.004852 0.008767

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.46 2.74 3.02 -5.37 1.44 -3.13 -3.93 -4.05 -2.73 -1.17 1.22 -2.85 -4.10 -6.12 -1.16
Bud Neck 2.14 1.62 -1.44 -13.66 -11.44 0.86 -1.19 -8.62 -8.68 -7.40 0.86 -1.72 -15.70 -16.13 -12.69
Bud Site 3.26 1.59 -0.72 -14.34 -6.61 1.52 -3.43 -10.11 -10.32 -9.47 0.95 -5.51 -17.80 -18.28 -14.80
Cell Periphery 3.64 2.86 3.52 -0.79 1.16 -2.24 0.99 -3.69 -0.76 -4.24 -1.02 -0.63 -2.13 -1.48 -0.88
Cytoplasm 2.87 -1.35 -11.91 -20.60 -13.32 2.24 -0.70 -13.33 -13.56 -13.23 3.70 -5.59 -24.02 -24.62 -21.84
Cytoplasmic Foci 3.15 -4.56 1.42 -5.15 13.60 1.91 -17.69 -0.78 -2.18 12.87 4.90 -19.76 0.36 -4.60 20.41
Eisosomes 3.29 3.25 3.28 -0.96 0.87 -3.65 0.17 -3.59 -0.59 -3.76 2.19 2.49 1.75 -1.94 -2.98
Endoplasmic Reticulum 2.67 -3.73 2.40 -2.30 6.62 -1.19 -2.71 -7.70 -3.54 -2.96 1.42 -6.48 -1.61 -2.88 6.07
Endosome -6.52 3.44 -3.68 6.60 -18.89 -7.47 1.88 -6.26 -0.61 -7.71 -10.81 6.75 -5.71 4.74 -13.21
Golgi -3.33 0.51 9.05 36.82 19.26 2.62 11.58 51.42 47.61 39.26 4.09 13.86 54.97 58.13 42.36
Lipid Particles 2.41 -0.45 2.92 1.85 9.52 -4.60 -2.97 -5.06 2.00 -1.75 -4.93 -8.77 -4.88 2.50 6.18
Mitochondria -0.15 2.73 1.18 3.58 -8.68 1.48 8.79 5.83 3.84 -2.17 1.20 9.57 5.57 4.90 -6.87
Mitotic Spindle 1.69 -2.03 -1.42 -12.48 1.51 3.34 -7.76 -9.67 -9.99 -6.78 3.60 -10.77 -14.56 -15.89 -5.66
None 1.29 1.26 0.51 -2.74 -2.68 1.26 3.19 -1.52 -1.55 -1.58 0.98 2.38 -1.74 -1.81 -1.89
Nuclear Periphery 1.67 -1.48 -0.70 -11.67 1.59 0.32 -4.35 -8.34 -8.49 -5.65 1.25 -6.45 -12.44 -14.07 -3.77
Nuclear Periphery Foci 1.85 -6.55 0.66 -4.69 7.12 -0.78 -4.11 -4.88 -4.75 -1.77 0.05 -8.11 -6.52 -6.70 6.18
Nucleolus 1.09 1.12 0.92 -6.66 -11.16 0.58 1.06 -2.54 -2.64 -2.69 1.07 1.49 -2.77 -3.84 -4.11
Nucleus 1.44 1.30 -0.40 -8.56 -7.83 0.84 1.15 -6.02 -6.11 -6.13 1.55 0.89 -9.70 -10.52 -10.33
Peroxisomes 2.63 3.24 -0.02 -9.71 -12.46 -1.97 1.72 -7.62 -6.16 -8.58 -1.18 3.25 -11.66 -11.32 -14.67
Vacuole -2.95 -5.06 -26.01 -26.76 -23.91 7.37 -1.10 -22.57 -24.51 -22.23 3.03 -2.90 -35.48 -37.41 -34.37
Vacuole Periphery -2.95 1.99 -0.53 3.97 -7.36 6.29 7.40 3.50 -2.05 -2.62 3.13 8.39 4.66 1.49 -5.35
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Alpha-1,2-mannosyltransferase; responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
Localization
Cell Percentages Golgi (53%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mnn5

Mnn5


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mnn5-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available