Standard name
Human Ortholog
Description Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0.09 0 0
Bud 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Cytoplasm 0 0 – 0.1 0.09 0.09 – 0.13 0.06 0.05 0.06 0.08 – – – 0.08 – 0.08 0 0 0 0 0.06 0
Endoplasmic Reticulum 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Endosome 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0.11 0 0
Golgi 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Mitochondria 0.46 0.53 – 0.67 0.52 0.47 – 0.22 0.36 0.37 0.4 0.31 – – – 0.22 – 0.2 0 0 0 0.2 0 0.06
Nucleus 0.42 0.05 – 0.11 0.05 0.06 – 0.06 0.07 0 0.06 0.09 – – – 0.25 – 0.34 0.4 0.31 0.17 0.16 0.07 0.11
Nuclear Periphery 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Nucleolus 0.87 1.0 – 0.85 0.84 0.82 – 0.79 0.82 0.81 0.8 0.75 – – – 0.63 – 0.66 0.53 0.58 0.72 0.12 0.63 0.54
Peroxisomes 0 0 – 0 0 0 – 0 0 0 0 0.05 – – – 0 – 0 0 0 0 0 0 0.05
SpindlePole 0 0 – 0 0 0 – 0 0 0.05 0.06 0.09 – – – 0 – 0 0 0 0 0.08 0 0
Vac/Vac Membrane 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0.08 – 0 0 0.05 0 0.21 0.05 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Bud 0 0 – 0 0 0 – 1 1 1 1 1 – – – 0 – 0 0 0 0 0 0 0
Bud Neck 0 0 – 0 0 0 – 1 0 1 0 2 – – – 0 – 0 0 0 0 0 0 0
Bud Site 0 0 – 0 0 0 – 2 1 6 3 6 – – – 0 – 0 – – – – – –
Cell Periphery 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Cytoplasm 1 0 – 10 12 8 – 30 8 9 9 13 – – – 4 – 4 0 0 0 0 1 0
Endoplasmic Reticulum 0 0 – 0 0 0 – 0 0 0 0 1 – – – 1 – 2 0 0 0 0 0 0
Endosome 0 0 – 0 0 1 – 1 2 3 0 1 – – – 0 – 0 0 0 0 0 0 0
Golgi 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Mitochondria 41 10 – 68 69 44 – 51 49 62 56 53 – – – 11 – 10 0 0 0 0 0 1
Nucleus 38 1 – 11 6 6 – 14 9 4 8 16 – – – 13 – 17 34 15 7 0 1 2
Nuclear Periphery 0 0 – 0 0 0 – 0 0 0 0 0 – – – 0 – 0 0 0 0 0 0 0
Nucleolus 78 19 – 87 111 77 – 183 112 134 112 130 – – – 32 – 33 45 29 29 0 13 12
Peroxisomes 0 0 – 0 1 1 – 2 2 1 3 8 – – – 0 – 2 0 0 0 0 0 1
SpindlePole 0 0 – 0 0 2 – 8 5 8 9 15 – – – 0 – 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 – 0 1 0 – 5 2 2 2 2 – – – 4 – 0 3 2 1 1 1 1
Unique Cell Count 90 19 102 132 94 232 136 166 140 173 51 50 86 51 41 5 21 23
Labelled Cell Count 158 30 176 200 139 298 191 231 203 248 65 68 86 51 41 5 21 23


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 61.0 54.9 – 51.1 43.7 25.4 – 18.9 18.4 17.2 16.7 15.7 – – – 84.9 – 94.2 – – –
Std Deviation (1e-4) 17.9 16.0 – 24.8 26.3 12.7 – 9.2 10.1 9.0 11.1 8.6 – – – 43.0 – 52.8 – – –
Intensity Change (Log2) – – – – – – – – – – – – – – – – – – – – –


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 93.988 128.7436 105.9081 103.6699 64.0707 106.7181 113.1376 127.0214 112.4143 103.4738 88.678 98.0622 122.8817 153.409 134.6675 138.8847 76.6167 112.8774
Actin 0.0001 0 0 0 0.0003 0.0151 0.0001 0 0 0 0.001 0 0.0048 0 0 0 0.006 0.0058
Bud 0.0001 0 0 0 0.0003 0.0008 0.0001 0 0 0.0001 0.0003 0.0001 0.0002 0 0 0 0.0007 0.0002
Bud Neck 0 0 0 0 0.0003 0.0004 0.0001 0 0 0 0.0002 0.0001 0.0001 0.0001 0 0 0.0003 0.0005
Bud Periphery 0.0001 0 0 0 0.0001 0.0012 0.0001 0 0 0.0001 0.0002 0.0001 0.0002 0 0 0 0.0008 0.0005
Bud Site 0.0002 0 0 0 0.0004 0.0011 0.0004 0 0 0.0001 0.0003 0.0001 0.0004 0.0001 0 0 0.0012 0.0003
Cell Periphery 0.0005 0.0007 0.0003 0.0001 0.0001 0.0003 0.0003 0.0004 0.0004 0.0007 0.0008 0.0002 0.0005 0.0002 0.0002 0.0002 0.0043 0.0007
Cytoplasm 0 0.0311 0 0 0.0002 0.0006 0.0002 0 0 0 0.0005 0 0.0003 0.0163 0 0 0.0022 0.0004
Cytoplasmic Foci 0.0001 0 0 0 0.0002 0.003 0.001 0 0 0 0.0026 0 0.0032 0.0147 0 0 0.0139 0.0013
Eisosomes 0.0001 0 0 0 0.0001 0.0002 0 0 0 0 0.0011 0 0.0001 0 0 0 0.0002 0.0001
Endoplasmic Reticulum 0 0 0 0 0 0.0008 0 0 0 0 0 0 0 0 0 0 0.0022 0.0025
Endosome 0 0 0 0 0 0.0051 0.0004 0 0 0 0 0 0.0016 0 0 0 0.0401 0.0259
Golgi 0 0 0 0 0 0.0023 0.0002 0 0 0 0.0001 0 0.0041 0.0001 0 0 0.0082 0.0107
Lipid Particles 0.0001 0 0.0001 0 0.0002 0.0049 0.0012 0 0 0 0.0008 0.0001 0.0261 0.0009 0 0 0.0291 0.0016
Mitochondria 0.0088 0.0064 0.0046 0.0031 0.0051 0.0131 0.0059 0.0042 0.0029 0.0132 0.0957 0.0036 0.0386 0.0048 0.0014 0.0063 0.0223 0.0227
None 0.0002 0 0 0 0.0003 0.002 0.0003 0 0 0.0001 0.0026 0 0.0002 0.0001 0 0 0.0054 0.0003
Nuclear Periphery 0.0006 0.0001 0.0001 0 0.001 0.0121 0.0064 0.0001 0.0003 0.0004 0.0029 0.0001 0.0009 0.001 0.0001 0 0.038 0.0316
Nucleolus 0.6612 0.6111 0.828 0.9396 0.4139 0.7056 0.7418 0.6556 0.5756 0.7483 0.7506 0.6064 0.4388 0.5367 0.7257 0.743 0.6725 0.6337
Nucleus 0.3249 0.3475 0.1647 0.0565 0.5593 0.2172 0.2353 0.3374 0.4183 0.2344 0.128 0.388 0.4454 0.4211 0.2718 0.2496 0.1026 0.2488
Peroxisomes 0.0001 0 0 0 0.0001 0.0018 0.0002 0 0 0.0001 0.0006 0 0.0292 0.0006 0 0 0.0049 0.0002
Punctate Nuclear 0.0003 0 0 0 0.0177 0.0081 0.0036 0 0 0.0001 0.0045 0.0001 0.0024 0.0017 0 0 0.0274 0.0009
Vacuole 0.0006 0.0009 0.0004 0.0002 0.0001 0.0011 0.0007 0.0004 0.0007 0.0007 0.0008 0.0003 0.0006 0.0003 0.0002 0.0001 0.007 0.0023
Vacuole Periphery 0.002 0.002 0.0017 0.0004 0.0002 0.0031 0.0016 0.0018 0.0016 0.0017 0.0063 0.0007 0.0021 0.0011 0.0005 0.0007 0.0108 0.0089

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2241.9044 2241.3077 2538.4875 2474.369 2440.7771 2138.241 2072.6827 1872.9358 2033.9919 2029.304
Translational Efficiency 1.9384 1.9949 1.9325 1.3199 2.0263 2.0074 1.9638 2.1296 1.8542 2.1683

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
492 712 2482 1282 173 336 131 502 665 1048 2613 1784

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 2215.00 4284.21 5898.14 8330.15 2527.64 4042.34 8656.85 2523.34 2296.33 4206.66 6036.45 6696.17
Standard Deviation 763.94 1332.22 3391.62 3118.03 875.71 1311.86 2170.96 2656.49 806.28 1330.52 3394.87 3973.73
Intensity Change Log 2 — 0.951722 1.412953 1.911036 — 0.677400 1.776051 -0.002456 — 0.812028 1.617752 1.194397

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000404 0.000585 0.000861 0.002794 0.000354 0.000569 0.000860 0.000768 0.000391 0.000580 0.000861 0.002224
Bud Neck 0.001295 0.002293 0.003766 0.004047 0.001033 0.002367 0.004453 0.012146 0.001226 0.002316 0.003800 0.006326
Bud Site 0.000171 0.001086 0.001256 0.002074 0.000317 0.000683 0.000848 0.003843 0.000209 0.000957 0.001235 0.002572
Cell Periphery 0.000015 0.000077 0.000327 0.000243 0.000042 0.000074 0.000068 0.000303 0.000022 0.000076 0.000314 0.000260
Cytoplasm 0.000068 0.001898 0.003669 0.001263 0.000272 0.000135 0.000112 0.009173 0.000121 0.001333 0.003491 0.003489
Cytoplasmic Foci 0.002131 0.010323 0.012316 0.008887 0.011795 0.006567 0.011603 0.012820 0.004645 0.009119 0.012280 0.009994
Eisosomes 0.000133 0.000368 0.000880 0.001365 0.000183 0.000247 0.000674 0.000114 0.000146 0.000329 0.000869 0.001013
Endoplasmic Reticulum 0.000096 0.000166 0.000202 0.000263 0.000082 0.000086 0.000061 0.001742 0.000093 0.000141 0.000195 0.000680
Endosome 0.000013 0.000197 0.000212 0.001909 0.000028 0.000022 0.000009 0.003417 0.000017 0.000141 0.000202 0.002333
Golgi 0.000067 0.000142 0.000091 0.001950 0.000092 0.000115 0.000107 0.000818 0.000074 0.000133 0.000092 0.001632
Lipid Particles 0.000007 0.000378 0.000014 0.000119 0.000008 0.000042 0.000011 0.000322 0.000007 0.000270 0.000014 0.000176
Mitochondria 0.001017 0.001158 0.001849 0.004440 0.000654 0.001433 0.002449 0.008819 0.000923 0.001246 0.001879 0.005672
Mitotic Spindle 0.000594 0.001182 0.001119 0.001696 0.003006 0.001796 0.000393 0.024253 0.001222 0.001379 0.001083 0.008043
None 0.000477 0.000806 0.002059 0.001149 0.001044 0.000645 0.000543 0.002676 0.000624 0.000754 0.001983 0.001578
Nuclear Periphery 0.000323 0.000231 0.000217 0.000979 0.000090 0.000072 0.000090 0.005496 0.000262 0.000180 0.000210 0.002250
Nuclear Periphery Foci 0.000167 0.000768 0.000082 0.000603 0.000412 0.000100 0.000025 0.006345 0.000231 0.000554 0.000079 0.002219
Nucleolus 0.638451* 0.470439* 0.377123* 0.611127* 0.551060* 0.489071* 0.593559* 0.386312* 0.615716* 0.476413* 0.387974* 0.547866*
Nucleus 0.319683* 0.473435* 0.577910* 0.305614* 0.376289* 0.445695* 0.304638* 0.488054* 0.334409* 0.464541* 0.564210* 0.356951*
Peroxisomes 0.033410 0.031953 0.011448 0.021661 0.052445 0.048190 0.075425 0.012492 0.038362 0.037159 0.014655 0.019081
Vacuole 0.000278 0.001446 0.001486 0.007637 0.000232 0.001014 0.001188 0.009631 0.000266 0.001308 0.001471 0.008198
Vacuole Periphery 0.001200 0.001070 0.003115 0.020179 0.000560 0.001076 0.002883 0.010455 0.001033 0.001072 0.003103 0.017443

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.31 -13.35 -5.18 -4.71 -4.19 -3.42 -6.55 -4.79 -2.49 -0.09 -4.39 -15.99 -5.58 -4.93 -4.17
Bud Neck -2.85 -13.30 -7.37 -2.52 -0.54 -3.72 -6.98 -8.70 -7.64 -6.23 -3.90 -15.36 -11.02 -7.29 -5.76
Bud Site -2.43 -13.55 -3.72 -0.76 -1.57 -2.23 -3.65 -5.57 -5.09 -4.94 -2.71 -13.39 -6.04 -2.76 -3.59
Cell Periphery -2.60 -10.46 -6.66 -2.89 1.67 -0.73 -0.48 -6.35 -5.03 -4.39 -2.72 -10.04 -8.84 -4.64 1.08
Cytoplasm -2.38 -11.96 -3.23 0.00 2.45 0.59 0.72 -4.63 -4.71 -4.72 -2.32 -11.61 -5.61 -3.00 -0.84
Cytoplasmic Foci -2.84 -5.21 -2.85 0.97 2.14 0.88 0.07 -0.55 -2.48 -0.83 -1.89 -3.73 -2.53 -0.11 1.42
Eisosomes -7.89 -6.80 -8.49 -6.76 -2.73 -2.10 -2.82 3.19 5.28 3.24 -8.14 -6.91 -8.23 -6.39 -1.03
Endoplasmic Reticulum -0.80 -3.17 -5.36 -0.94 -0.81 -0.16 0.74 -8.60 -8.63 -8.79 -0.80 -3.21 -9.53 -6.57 -7.01
Endosome -2.05 -1.14 -2.42 -2.13 -2.10 0.34 0.98 -3.66 -3.67 -3.68 -2.02 -1.12 -3.74 -3.49 -3.32
Golgi -1.81 -1.66 -2.28 -2.15 -2.25 -0.77 -0.51 -4.31 -4.12 -4.23 -2.00 -1.37 -2.65 -2.51 -2.61
Lipid Particles -1.44 -1.85 -3.28 1.03 -3.01 -1.99 -0.82 -4.61 -4.08 -4.58 -1.50 -1.92 -5.53 0.51 -5.25
Mitochondria -0.80 -6.30 -9.26 -8.23 -7.15 -3.45 -5.71 -3.44 -3.08 -2.63 -2.06 -8.82 -6.70 -6.12 -5.28
Mitotic Spindle -0.86 -1.96 -1.51 -0.30 -0.57 0.40 1.11 -4.61 -5.05 -5.42 -0.34 0.03 -4.85 -4.65 -5.13
None -2.49 -4.07 -6.16 -1.83 2.23 1.18 1.39 -4.09 -7.94 -7.62 -1.16 -3.59 -7.08 -5.80 0.95
Nuclear Periphery 0.31 0.82 -3.21 -3.01 -4.24 0.44 0.05 -3.59 -3.61 -3.60 0.45 0.44 -4.43 -4.50 -4.58
Nuclear Periphery Foci -1.47 1.50 -1.75 0.52 -2.17 0.96 1.20 -3.28 -3.49 -3.53 -1.15 1.60 -3.64 -2.67 -3.96
Nucleolus 9.56 17.40 1.84 -9.70 -21.09* 2.38 -1.24 7.23 5.58 7.88 9.49 17.45 5.30 -5.41 -15.28
Nucleus -8.19 -16.78 0.78 11.20 25.42 -2.48 2.05 -4.18 -1.77 -6.05 -8.31 -17.14 -1.61 8.52 21.07
Peroxisomes 0.51 9.15 4.03 3.95 -5.97 0.51 -2.00 6.72 7.30 6.00 0.36 9.67 7.27 7.59 -3.00
Vacuole -2.11 -7.48 -9.24 -4.40 -7.59 -1.61 -5.29 -4.33 -3.92 -3.93 -2.43 -8.03 -9.27 -6.02 -7.80
Vacuole Periphery 0.09 -2.76 -11.51 -12.30 -10.77 -2.17 -7.66 -3.23 -3.03 -2.40 -0.21 -3.71 -11.31 -11.74 -10.03
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein component of the small (40S) ribosomal subunit; homologous to mammalian ribosomal protein S15A and bacterial S8; RPS22A has a paralog, RPS22B, that arose from the whole genome duplication
Localization
Cell Percentages nucleolus (48%), nucleus (20%), mixed (31%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Rps22a

Rps22a


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rps22a-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available