Standard name
Human Ortholog
Description Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.05 0.07 0.08 0.13 0.14
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.08 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.08 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.07 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0.05 0.13 0.08 0.07 0 0 0.16 0 0.06 0 0.08 0 0 0 0.22 0.21 0.18 0.17 0.36 0.36 0.3 0.32 0.29
Mitochondria 0.85 0.92 0.69 0.83 0.88 0.88 0.86 0.66 0.91 0.88 0.92 0.9 0.92 0.94 0.92 0.15 0.16 0.17 0.55 0.38 0.44 0.39 0.37 0.42
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.35 0.18 0.19 0.15 0.22 0.29 0.28 0.31 0.24 0.18 0.17 0.12 0.18 0.15 0.12 0.26 0.27 0.3 0 0.06 0 0.06 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.26 0.16 0.26 0.11 0.24 0.23 0.16 0.16 0.11 0.1 0.08 0.07 0.24 0.25 0.19 0.42 0.34 0.4 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 1 2 1 3 5 6 2 8 3 8 0 0 1 0 0 0 11 12 23 15 39 50
Bud 0 0 1 1 1 2 2 1 0 0 1 1 0 1 1 0 0 0 0 1 0 0 0 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 2 5 3 1 0 0 1 0 4 1 1 1 4 2 7 8 1 5 1 1 0 3 2
Cytoplasm 9 8 8 7 2 1 1 4 5 6 2 3 8 3 2 27 15 14 1 4 0 1 0 0
Endoplasmic Reticulum 0 1 0 0 1 1 0 0 0 3 1 0 1 0 1 22 13 6 1 4 1 0 1 3
Endosome 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 3 2
Golgi 0 10 30 15 18 7 17 100 5 27 10 30 1 7 8 72 40 27 24 98 113 54 97 101
Mitochondria 93 197 154 147 218 347 491 401 406 422 349 358 252 307 314 47 31 26 79 104 138 72 112 145
Nucleus 1 1 0 0 1 2 3 2 0 0 1 0 0 0 1 2 3 5 1 1 0 2 2 0
Nuclear Periphery 0 0 0 0 0 0 0 1 0 2 1 3 0 0 0 0 0 0 1 0 0 0 0 1
Nucleolus 39 38 42 26 55 114 162 187 108 87 64 47 49 48 40 84 52 46 2 15 11 11 10 12
Peroxisomes 0 0 0 0 1 0 1 1 0 0 0 1 0 0 1 1 0 0 5 2 8 7 20 13
SpindlePole 0 0 0 0 1 0 0 0 0 2 0 0 0 0 0 2 1 0 0 0 0 0 0 0
Vac/Vac Membrane 29 35 58 20 61 92 90 99 51 48 29 29 66 81 64 136 65 61 0 12 3 7 2 3
Unique Cell Count 110 214 223 177 249 396 570 610 445 482 379 398 274 328 341 322 191 151 144 276 318 184 308 350
Labelled Cell Count 172 293 299 221 362 569 772 803 577 609 462 482 378 451 435 400 228 186 144 276 318 184 308 350


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 176.3 144.3 134.7 129.6 100.5 83.4 69.3 65.5 59.1 53.5 48.3 49.4 140.9 132.1 121.3 154.2 160.2 147.8 129.3 136.8 139.9
Std Deviation (1e-4) 43.3 38.4 33.0 35.6 30.2 24.7 22.0 19.2 18.2 17.4 15.8 16.7 35.5 32.6 28.7 59.6 58.3 56.8 39.7 38.2 40.8
Intensity Change (Log2) – – – -0.06 -0.42 -0.69 -0.96 -1.04 -1.19 -1.33 -1.48 -1.45 0.07 -0.03 -0.15 0.2 0.25 0.13 -0.06 0.02 0.05

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100150200WT3HU80HU120HU160050100150200WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150200WT1AF100AF140AF180050100150200
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1.1 0
Cytoplasm 0.2 0 0 0 0 0 0 0 0 -0.4 0 0 2.2 1.9 2.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 4.0 4.0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi -1.6 -2.2 -5.9 -5.6 1.0 -6.7 -3.6 -5.1 -2.4 -6.0 -5.2 -5.1 2.6 2.0 1.2
Mitochondria 3.2 4.9 5.6 5.6 -0.9 7.3 5.9 7.4 6.6 6.6 7.6 7.1 -13.0 -10.8 -9.8
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.1 0.9 2.7 2.8 3.4 1.6 -0.3 -0.6 -2.4 -0.3 -1.3 -2.3 2.0 2.0 2.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -3.7 -0.4 -0.8 -3.3 -3.2 -4.8 -5.5 -6.2 -6.4 -0.5 -0.3 -2.0 3.9 1.8 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 169.2444 195.1634 167.3263 159.8531 141.4156 181.2902 197.152 207.0227 183.003 155.306 180.0579 187.0813 203.9845 247.1402 213.7222 166.1827 222.908 230.6499
Actin 0.0047 0.0003 0.0011 0.0004 0.0109 0 0.0018 0.0003 0.0124 0.0208 0.0002 0.0002 0.0097 0.0001 0.0165 0.0004 0.0047 0.0001
Bud 0.0001 0 0 0 0.0004 0 0 0 0.0001 0.0001 0 0 0.0001 0 0.0001 0 0 0
Bud Neck 0.0001 0 0.0001 0.0003 0.0005 0 0 0 0.0001 0.0001 0 0 0.0001 0 0.0003 0 0.0001 0
Bud Periphery 0.0001 0 0 0 0.0006 0 0 0 0.0002 0.0005 0 0 0.0001 0 0.0002 0 0.0001 0
Bud Site 0.0005 0 0.0003 0 0.0042 0 0.0002 0 0.0004 0.0006 0 0 0.0002 0 0.0004 0 0.0001 0
Cell Periphery 0.0002 0.0002 0.0001 0.0003 0.0002 0 0.0003 0.0005 0.0004 0.0003 0.0001 0.0001 0.0002 0.0003 0.0004 0.0001 0 0
Cytoplasm 0.0005 0 0 0 0.0003 0 0.0001 0 0 0 0 0 0.0002 0 0.0001 0 0.0001 0
Cytoplasmic Foci 0.0089 0 0.0073 0.0001 0.0377 0 0.0083 0 0.0028 0.0021 0.001 0 0.0045 0 0.0066 0.0001 0.0016 0
Eisosomes 0.0029 0.0119 0.0037 0.0019 0.0014 0.0003 0.0069 0.003 0.005 0.005 0.0015 0.0014 0.0044 0.0033 0.0067 0.0021 0.0007 0.0017
Endoplasmic Reticulum 0.0003 0 0 0 0.0009 0 0 0 0 0.0003 0 0 0.0014 0 0.0002 0 0.0001 0
Endosome 0.0028 0 0.0003 0 0.0045 0 0 0 0.0004 0.002 0 0 0.0047 0 0.0014 0 0.0035 0
Golgi 0.0017 0 0.0004 0 0.0037 0 0.0001 0.0001 0.0013 0.0083 0.0003 0.0001 0.0033 0 0.003 0 0.0029 0
Lipid Particles 0.0067 0.0015 0.0058 0.0005 0.0132 0.0005 0.003 0.0029 0.0069 0.0869 0.0101 0.0013 0.0175 0.0012 0.0095 0.0015 0.0085 0.0001
Mitochondria 0.9332 0.9785 0.9646 0.9885 0.8337 0.9982 0.9505 0.985 0.9465 0.846 0.9679 0.9934 0.9223 0.9855 0.9282 0.9897 0.9727 0.9972
None 0.0021 0 0.0005 0 0.0025 0 0.0014 0 0.0001 0.0005 0.0001 0 0.0007 0 0.0012 0 0.0002 0
Nuclear Periphery 0.0015 0 0 0 0.0188 0 0.0001 0 0 0.0074 0.0001 0 0.0035 0 0.0002 0 0.0005 0
Nucleolus 0.0204 0.001 0.0063 0.0002 0.0471 0 0.0173 0.0006 0.005 0.0025 0.0033 0.0012 0.0053 0.0008 0.0112 0.0015 0.0001 0
Nucleus 0.0012 0.0001 0.0003 0 0.0034 0 0.0006 0.0001 0.0002 0.0009 0.0002 0.0001 0.0005 0.0001 0.0005 0.0002 0.0001 0
Peroxisomes 0.008 0.0008 0.0073 0.0074 0.0065 0.0002 0.0034 0.0008 0.0057 0.0048 0.0029 0.0005 0.0086 0.0012 0.0052 0.0034 0.0026 0.0005
Punctate Nuclear 0.0017 0 0.0002 0 0.0062 0 0.0001 0 0 0.0011 0 0 0.0032 0 0.0002 0 0.0007 0
Vacuole 0.0006 0.0006 0.0002 0.0001 0.0007 0 0.0003 0.0006 0.0015 0.0009 0.0003 0.0001 0.0005 0.0007 0.0007 0.0001 0.0001 0
Vacuole Periphery 0.0019 0.005 0.0014 0.0003 0.0025 0.0007 0.0055 0.006 0.0108 0.0088 0.0119 0.0016 0.0089 0.0067 0.007 0.0009 0.0007 0.0003

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 247.684 209.761 180.6672 191.5908 203.7264 201.9462 227.2384 193.5594 164.1934 188.0417
Translational Efficiency 0.9389 1.1068 1.0706 0.9321 0.9473 1.2812 0.9626 0.9687 1.0883 1.0169

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
23 1321 2376 1483 1339 1299 136 795 1362 2620 2512 2278

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 293.87 9779.80 9597.26 7622.78 9268.07 10189.22 8795.10 7367.97 9116.52 9982.79 9553.83 7533.85
Standard Deviation 6.10 3312.08 3185.15 2016.75 2780.58 3160.14 2217.38 2097.99 2989.67 3244.11 3145.64 2049.07
Intensity Change Log 2 — 5.056555 5.029373 4.697067 — 0.136703 -0.075569 -0.331002 — 1.062388 0.943731 0.648697

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000045 0.005355 0.002276 0.005591 0.002290 0.005404 0.009610 0.008629 0.002252 0.005379 0.002673 0.006651
Bud Neck 0.000010 0.001811 0.001628 0.000937 0.001393 0.001345 0.012127 0.002832 0.001369 0.001580 0.002197 0.001598
Bud Site 0.000015 0.000915 0.002146 0.000603 0.001110 0.000893 0.009860 0.003533 0.001092 0.000904 0.002564 0.001625
Cell Periphery 0.000054 0.000169 0.002323 0.000125 0.000113 0.000188 0.000421 0.000776 0.000112 0.000179 0.002220 0.000352
Cytoplasm 0.000024 0.000134 0.000233 0.000157 0.000089 0.000175 0.001326 0.000313 0.000088 0.000154 0.000292 0.000212
Cytoplasmic Foci 0.000015 0.017942 0.008322 0.009576 0.023023 0.019398 0.154033 0.018242 0.022635 0.018664 0.016211 0.012600
Eisosomes 0.000055 0.016401 0.020192 0.005051 0.014388 0.013832 0.009590 0.004297 0.014146 0.015127 0.019618 0.004788
Endoplasmic Reticulum 0.000000 0.000087 0.000058 0.000053 0.000036 0.000047 0.000144 0.000461 0.000036 0.000067 0.000063 0.000195
Endosome 0.000001 0.000134 0.000182 0.000516 0.000075 0.000126 0.000513 0.001598 0.000074 0.000130 0.000200 0.000893
Golgi 0.000004 0.003517 0.000678 0.005585 0.002499 0.003918 0.005053 0.010241 0.002457 0.003716 0.000915 0.007210
Lipid Particles 0.000037 0.004219 0.001166 0.001163 0.002946 0.004868 0.006722 0.004983 0.002897 0.004541 0.001467 0.002496
Mitochondria 0.000008 0.912473 0.927056 0.953339 0.911613 0.903010 0.687786 0.881000 0.896219 0.907781 0.914102 0.928094
Mitotic Spindle 0.000400 0.000381 0.000211 0.000494 0.000579 0.000425 0.010610 0.001865 0.000576 0.000403 0.000774 0.000972
None 0.999159 0.007498 0.004997 0.003175 0.010529 0.009396 0.005219 0.007289 0.027224 0.008439 0.005009 0.004611
Nuclear Periphery 0.000000 0.000273 0.000263 0.000189 0.000382 0.000484 0.002882 0.001109 0.000375 0.000378 0.000404 0.000510
Nuclear Periphery Foci 0.000035 0.000288 0.000113 0.000070 0.000172 0.000190 0.000716 0.000346 0.000169 0.000239 0.000145 0.000166
Nucleolus 0.000027 0.002500 0.002787 0.000676 0.003492 0.003435 0.014165 0.002003 0.003434 0.002963 0.003403 0.001139
Nucleus 0.000008 0.000157 0.000428 0.000150 0.000150 0.000509 0.002168 0.001196 0.000148 0.000331 0.000522 0.000515
Peroxisomes 0.000102 0.009043 0.004475 0.006058 0.006702 0.007637 0.041988 0.005436 0.006591 0.008346 0.006506 0.005841
Vacuole 0.000001 0.006476 0.010446 0.002367 0.006536 0.009390 0.013875 0.013467 0.006426 0.007921 0.010632 0.006241
Vacuole Periphery 0.000000 0.010226 0.010020 0.004124 0.011883 0.015331 0.011191 0.030384 0.011683 0.012757 0.010083 0.013288

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.50 -8.66 -8.40 -0.20 -4.68 -2.86 -3.28 -3.12 -1.47 0.31 -3.74 -0.77 -4.67 -1.20 -4.64
Bud Neck -5.02 -6.01 -6.50 2.26 2.27 0.15 -5.03 -2.92 -3.23 4.29 -0.65 -2.24 -0.82 -0.17 1.77
Bud Site -4.14 -6.21 -5.42 1.26 4.28 0.45 -2.38 -2.52 -2.85 1.62 0.45 -2.63 -1.17 -2.09 1.61
Cell Periphery -3.99 -3.94 -1.99 1.03 3.81 -1.38 -1.70 -2.34 -2.06 -0.76 -1.79 -3.88 -2.31 -1.68 3.36
Cytoplasm -4.79 -4.13 -4.85 -0.79 1.29 -1.70 -1.47 -3.70 -1.86 1.38 -2.26 -2.35 -4.29 -1.62 1.40
Cytoplasmic Foci -9.43 -9.25 -7.02 3.45 -0.87 1.29 -7.24 1.27 0.19 7.43 1.64 2.53 4.10 3.08 1.75
Eisosomes -12.60 -14.84 -10.70 8.24 10.55 0.37 2.12 9.14 7.90 2.42 -0.74 -3.35 8.85 11.18 11.12
Endoplasmic Reticulum -2.17 -8.15 -6.57 0.84 0.52 -1.50 -2.11 -2.01 -1.96 -1.46 -1.52 -3.23 -2.16 -1.68 -1.78
Endosome -6.20 -6.09 -2.21 -1.63 -1.42 -1.75 -4.25 -1.78 -1.72 -1.26 -2.82 -4.17 -2.45 -2.28 -2.06
Golgi -6.80 -7.46 -7.42 -2.26 -6.48 -2.59 -2.48 -5.03 -4.01 -2.90 -2.76 4.90 -6.10 -4.37 -8.65
Lipid Particles -6.37 -7.43 -3.22 4.11 0.01 -2.50 -2.26 -1.87 -0.10 0.89 -2.85 3.89 0.73 3.17 -2.23
Mitochondria -194.06 -287.50 -300.68 -7.17 -5.77 1.30 7.75 3.51 2.50 -6.53 -1.79 -2.64 -4.80 -4.00 -2.74
Mitotic Spindle 0.08 1.50 -0.62 -0.65 -2.36 0.47 -3.43 -1.50 -1.71 2.85 0.58 -0.61 -1.03 -1.81 -0.65
None 2442.97 3583.10 3657.66 11.28 7.51 1.63 6.60 4.32 3.30 -2.75 5.36 6.35 6.46 11.33 1.49
Nuclear Periphery -8.20 -8.00 -8.10 2.06 1.82 -1.33 -3.88 -5.22 -4.15 2.71 -0.05 -0.52 -2.19 -2.12 -1.49
Nuclear Periphery Foci -1.57 -3.79 -1.70 1.36 2.56 -0.45 -4.84 -2.81 -2.32 2.99 -0.83 0.93 0.07 0.85 -0.82
Nucleolus -6.03 -6.46 -7.81 4.34 4.83 0.07 -3.07 2.38 2.46 3.52 0.74 0.04 4.13 5.28 4.88
Nucleus -4.69 -3.56 -1.69 -0.05 1.78 -1.27 -2.02 -1.23 -0.80 1.36 -1.30 -3.06 -1.24 -0.61 0.24
Peroxisomes -7.43 -9.02 -6.84 2.01 -1.59 -0.63 -4.62 0.86 1.30 4.76 -1.46 0.11 0.67 2.26 0.66
Vacuole -7.38 -10.35 -5.02 4.11 7.25 -1.92 -3.22 -3.33 -1.80 0.65 -1.37 -3.47 0.13 1.52 3.63
Vacuole Periphery -7.69 -11.56 -7.94 4.27 5.84 -1.68 0.28 -5.09 -4.06 -5.07 -0.64 1.01 -0.88 -0.34 -2.13
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol
Localization
Cell Percentages mitochondrion (64%)
Cell Cycle Regulation No
Subcompartmental Group mito-3

Aco2

Aco2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Aco2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available