Standard name
Human Ortholog
Description Subunit of the SF3a splicing factor complex; required for spliceosome assembly
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.1 0.18 0.1 0.11 0.12 0 0 0 0.05 0 0.05
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.29 0 0 0 0.08 0.11 0.09 0.55 0.31 0.35 0.34 0 0 0 0.05 0.08 0 0 0 0 0 0 0
Nucleus 0.93 0.89 0.95 0.95 0.93 0.93 0.89 0.86 0.84 0.84 0.85 0.85 0.91 0.89 0.8 0.85 0.82 0.84 0.91 0.89 0.88 0.81 0.8 0.66
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.06 0.06 0.14
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 0 0 0
Bud 0 1 0 0 0 0 4 1 5 2 6 6 0 2 0 1 0 0 2 3 3 1 3 6
Bud Neck 0 0 0 0 0 0 0 1 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 1 7 12 8 16 14 23 11 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2 11 14 12 12 14 19 30 16 21 10 8 11 33 56 19 18 22 0 5 4 7 13 14
Endoplasmic Reticulum 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 7 4 7 0 0 1 0 1 1
Endosome 1 0 3 0 0 3 3 7 0 2 0 0 0 0 1 0 1 0 3 3 2 1 2 4
Golgi 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1
Mitochondria 8 74 1 6 5 42 87 65 272 201 202 188 3 6 1 10 13 4 0 3 3 1 3 8
Nucleus 174 227 401 275 315 483 690 622 416 543 492 470 116 293 250 160 139 152 176 225 396 115 248 179
Nuclear Periphery 1 0 8 2 3 10 19 4 4 10 2 4 0 2 0 2 3 3 0 0 2 0 3 1
Nucleolus 9 4 1 2 3 7 13 25 10 24 25 15 1 1 0 3 0 2 1 1 4 3 6 8
Peroxisomes 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 1 1 0 5 6 10 2 1 5 5 0 1 4 1 0 0 0 0 2 0 2 3
Vac/Vac Membrane 2 5 5 2 7 8 13 30 3 9 7 10 0 6 2 4 10 7 7 7 17 9 20 38
Unique Cell Count 187 256 424 290 337 522 772 727 498 648 576 556 127 330 312 188 169 182 193 254 453 142 310 273
Labelled Cell Count 197 322 436 300 346 579 867 804 745 827 774 718 132 344 315 207 188 197 193 254 453 142 310 273


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 4.6 7.0 6.2 6.8 5.3 5.3 5.6 4.1 4.7 4.4 4.8 7.4 6.4 6.0 6.5 7.4 8.3 9.6 9.2 9.4
Std Deviation (1e-4) 1.1 0.7 1.6 1.5 1.8 1.2 1.1 1.6 1.1 1.2 0.9 1.9 9.3 3.3 1.5 1.8 1.9 2.4 15.0 11.4 10.7
Intensity Change (Log2) – – – -0.16 -0.04 -0.4 -0.38 -0.31 -0.76 -0.57 -0.66 -0.55 0.09 -0.13 -0.21 -0.11 0.08 0.25 0.46 0.4 0.44

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6423 4.032 3.7039 3.209 3.4313 3.6814 4.6277 4.8623 4.5201 5.0963 4.3064 4.8528 1.4533 1.8441 1.6926 1.6447 1.3075 1.6064
Actin 0.0076 0 0.003 0 0.0004 0.0021 0.0472 0 0.0137 0 0.0001 0.0038 0.0009 0 0.0002 0.0034 0 0
Bud 0.0002 0 0.0001 0 0 0 0.0007 0 0.0004 0 0 0.0001 0.0002 0 0.0001 0.0001 0 0
Bud Neck 0.0043 0.0001 0.001 0 0.0004 0.0011 0.0014 0.0001 0.0012 0 0.0005 0.0012 0.0011 0 0.0002 0.0202 0.0003 0.0005
Bud Periphery 0.0006 0 0.0003 0 0 0 0.0021 0 0.0008 0 0 0.0002 0.0005 0 0.0001 0.0001 0 0
Bud Site 0.0031 0 0.0022 0 0.0001 0.0001 0.0022 0.0001 0.0027 0 0 0.0004 0.0006 0 0.0001 0.0014 0 0
Cell Periphery 0.0004 0 0.0001 0 0 0 0.0006 0 0.0002 0 0 0.0001 0.0001 0 0 0.0001 0 0
Cytoplasm 0.0014 0.0001 0.0007 0 0.0017 0.0001 0.0027 0 0.0012 0.0001 0.0004 0.0001 0.0021 0.0001 0.0004 0.0002 0.0003 0
Cytoplasmic Foci 0.0144 0 0.0014 0 0.002 0.0005 0.0071 0 0.0029 0 0 0.002 0.0011 0 0 0.0019 0 0
Eisosomes 0.0004 0 0 0 0 0 0.0017 0 0.0001 0 0 0 0 0 0 0.0001 0 0
Endoplasmic Reticulum 0.0079 0 0.0002 0 0.0009 0.0001 0.0026 0 0.0015 0 0.0002 0.0001 0.0011 0 0.0004 0 0 0
Endosome 0.0105 0 0.0009 0 0.0089 0.001 0.016 0 0.0075 0 0.0004 0.0044 0.0031 0 0.001 0.0003 0 0
Golgi 0.0038 0 0.0011 0 0.0016 0.0008 0.0067 0 0.0029 0 0 0.007 0.0003 0 0 0.0006 0 0
Lipid Particles 0.0193 0 0.0008 0 0.0261 0.0031 0.0118 0 0.0094 0 0 0.0032 0.0007 0 0 0.0005 0 0
Mitochondria 0.002 0.0001 0.0003 0.0001 0.0033 0.0011 0.0123 0.0002 0.0083 0.0003 0.0003 0.0181 0.0014 0 0.0007 0.0003 0.0001 0
None 0.0072 0 0.0009 0 0.0011 0.0001 0.0117 0 0.0003 0.0001 0.0001 0.0001 0.0008 0 0.0001 0.0001 0.0001 0
Nuclear Periphery 0.006 0.0005 0.0018 0.0006 0.0296 0.0004 0.0153 0.0022 0.0047 0.0032 0.0081 0.0003 0.0057 0.0007 0.0052 0.0003 0.0017 0.0002
Nucleolus 0.0086 0.0074 0.0114 0.0038 0.0149 0.0181 0.0123 0.0111 0.0042 0.0075 0.0214 0.02 0.0112 0.0045 0.0047 0.0034 0.0195 0.0198
Nucleus 0.8602 0.9832 0.9572 0.9953 0.8972 0.9692 0.8226 0.986 0.929 0.9877 0.9664 0.9354 0.9607 0.9942 0.9857 0.9639 0.9726 0.9764
Peroxisomes 0.0263 0 0.0006 0 0.003 0.0009 0.0099 0 0.0057 0 0 0.002 0.0001 0 0 0.0028 0 0
Punctate Nuclear 0.0135 0.0086 0.0154 0.0001 0.0068 0.0011 0.0034 0.0002 0.0012 0.0007 0.0013 0.001 0.0062 0.0003 0.0003 0.0003 0.0052 0.0029
Vacuole 0.0015 0 0.0005 0 0.001 0.0001 0.0069 0 0.0014 0 0.0005 0.0003 0.0017 0 0.0003 0 0 0
Vacuole Periphery 0.0007 0 0.0001 0 0.001 0.0001 0.0029 0 0.0007 0.0001 0.0004 0.0002 0.0006 0 0.0003 0 0 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 3.2723 5.8504 13.0237 9.6427 11.0308 5.2327 4.1407 13.9736 9.5865 9.4639
Translational Efficiency 6.9676 3.6763 1.3098 1.5341 1.6319 4.4217 5.5355 1.4157 2.0653 1.944

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2244 1279 1490 2662 1996 2048 2124 1403 4240 3327 3614 4065

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 787.52 846.15 879.27 982.34 725.90 910.07 940.48 945.66 758.51 885.50 915.24 969.68
Standard Deviation 94.86 119.08 121.38 132.06 95.80 114.74 119.85 137.94 100.14 120.51 124.19 135.25
Intensity Change Log 2 — 0.103597 0.158990 0.318906 — 0.326207 0.373626 0.381551 — 0.214661 0.265928 0.349293

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000090 0.000670 0.000527 0.000517 0.000148 0.000188 0.000516 0.000877 0.000117 0.000373 0.000520 0.000641
Bud Neck 0.002414 0.006908 0.014088 0.033763 0.003271 0.004473 0.015690 0.013501 0.002817 0.005409 0.015030 0.026770
Bud Site 0.000184 0.002375 0.001102 0.002640 0.000577 0.000810 0.001389 0.002936 0.000369 0.001412 0.001271 0.002742
Cell Periphery 0.000083 0.000134 0.000056 0.000096 0.000077 0.000097 0.000070 0.000143 0.000080 0.000111 0.000064 0.000112
Cytoplasm 0.002342 0.003706 0.001336 0.004749 0.002317 0.001660 0.001293 0.011623 0.002330 0.002447 0.001311 0.007122
Cytoplasmic Foci 0.000226 0.000936 0.000039 0.000528 0.000311 0.000856 0.000040 0.001217 0.000266 0.000887 0.000039 0.000766
Eisosomes 0.000012 0.000025 0.000022 0.000022 0.000012 0.000016 0.000026 0.000030 0.000012 0.000019 0.000024 0.000025
Endoplasmic Reticulum 0.002716 0.007283 0.003643 0.005574 0.002538 0.003830 0.004530 0.006699 0.002632 0.005158 0.004164 0.005962
Endosome 0.000163 0.000717 0.000228 0.001029 0.000160 0.001290 0.000248 0.002295 0.000161 0.001070 0.000240 0.001466
Golgi 0.000154 0.000369 0.000061 0.000747 0.000055 0.000286 0.000054 0.001082 0.000107 0.000318 0.000057 0.000862
Lipid Particles 0.000228 0.000308 0.000081 0.000114 0.000288 0.000241 0.000061 0.000305 0.000256 0.000267 0.000069 0.000180
Mitochondria 0.001244 0.003195 0.001428 0.003488 0.001167 0.003489 0.001276 0.003273 0.001208 0.003376 0.001339 0.003414
Mitotic Spindle 0.000762 0.001176 0.002225 0.014742 0.001320 0.003545 0.001016 0.007371 0.001024 0.002634 0.001514 0.012198
None 0.002519 0.004665 0.002018 0.002916 0.005011 0.002743 0.003905 0.011125 0.003692 0.003482 0.003127 0.005749
Nuclear Periphery 0.000766 0.000635 0.000334 0.003219 0.000471 0.001020 0.000567 0.000989 0.000627 0.000872 0.000471 0.002449
Nuclear Periphery Foci 0.000347 0.000395 0.000094 0.000918 0.000299 0.000959 0.000103 0.000799 0.000324 0.000742 0.000099 0.000877
Nucleolus 0.011107 0.017853 0.013033 0.006268 0.013572 0.012201 0.010763 0.007536 0.012267 0.014374 0.011699 0.006706
Nucleus 0.974084 0.945518 0.958691 0.913042 0.967637 0.958462 0.957121 0.920313 0.971049 0.953486 0.957768 0.915552
Peroxisomes 0.000213 0.001438 0.000181 0.000108 0.000283 0.000501 0.000121 0.000307 0.000246 0.000861 0.000146 0.000176
Vacuole 0.000222 0.001122 0.000650 0.003464 0.000364 0.002269 0.001022 0.005870 0.000289 0.001828 0.000868 0.004295
Vacuole Periphery 0.000125 0.000573 0.000163 0.002058 0.000125 0.001064 0.000191 0.001709 0.000125 0.000875 0.000179 0.001938

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.95 -19.48 -20.24 0.70 -1.63 -1.33 -15.17 -12.26 -11.71 -6.53 -7.09 -24.36 -20.39 -8.83 -5.84
Bud Neck -7.34 -13.52 -22.20 -18.39 -11.24 -1.95 -16.19 -13.48 -11.49 0.11 -5.87 -21.23 -25.32 -21.86 -10.08
Bud Site -2.75 -3.88 -8.15 -0.09 -3.11 -0.67 -2.73 -5.89 -6.00 -4.20 -2.95 -4.81 -9.20 -3.70 -4.88
Cell Periphery -2.00 1.39 0.03 2.77 -3.17 -0.81 0.39 -2.70 -1.15 -3.55 -1.66 1.23 -1.39 0.83 -4.27
Cytoplasm -1.60 1.89 -2.48 -0.34 -4.74 1.05 2.36 -5.62 -5.96 -6.51 -0.23 2.98 -5.94 -5.32 -8.18
Cytoplasmic Foci -2.30 2.64 -1.10 1.91 -3.60 -0.47 1.50 -0.47 0.01 -2.57 -1.68 2.05 -0.53 1.45 -4.00
Eisosomes -6.83 -10.39 -11.96 0.83 -0.69 -3.43 -12.59 -8.71 -7.21 -2.65 -7.45 -16.64 -13.86 -6.10 -1.39
Endoplasmic Reticulum -11.75 -5.42 -10.83 3.67 -7.37 -4.49 -10.98 -12.38 -7.75 -6.29 -10.79 -11.89 -16.38 -3.73 -8.35
Endosome -2.54 -1.08 -4.11 -0.05 -3.32 -3.25 -2.33 -2.88 -0.65 -2.69 -3.96 -2.38 -4.39 0.00 -3.94
Golgi -1.24 0.82 -1.18 -0.40 -1.72 -2.64 -0.51 -1.95 -1.28 -1.93 -2.17 0.77 -2.20 -1.21 -2.54
Lipid Particles -0.78 1.69 1.53 4.05 -0.59 0.64 1.90 0.05 -1.29 -5.13 0.16 2.57 1.24 2.23 -4.24
Mitochondria -1.88 -0.33 -3.72 -0.09 -3.10 -2.58 -0.39 -2.56 0.33 -2.78 -3.21 -0.51 -4.59 0.19 -4.78
Mitotic Spindle -0.82 -1.93 -6.42 -5.99 -4.06 -1.86 0.45 -4.12 -2.71 -4.41 -2.22 -1.34 -7.51 -5.66 -6.46
None -2.29 0.91 -0.42 2.33 -2.10 2.38 1.31 -2.43 -4.03 -3.30 0.31 1.17 -1.72 -2.00 -2.82
Nuclear Periphery 0.81 3.36 -6.81 -7.14 -8.29 -2.06 -1.53 -5.59 -0.78 -4.42 -1.36 1.35 -8.01 -5.93 -8.67
Nuclear Periphery Foci -0.20 1.32 -1.01 -0.99 -2.46 -1.53 1.36 -1.57 0.43 -2.75 -1.49 1.90 -1.71 0.23 -3.55
Nucleolus -4.56 -2.34 4.26 7.89 6.51 1.08 1.92 3.92 3.07 2.42 -2.26 -0.10 6.14 8.13 6.61
Nucleus 7.70 6.76 15.95 6.14 9.70 2.35 4.83 10.37 7.94 7.80 6.63 8.48 18.68 10.78 12.71
Peroxisomes -2.32 0.33 1.24 2.56 3.34 -0.89 1.99 0.06 1.01 -3.70 -2.52 1.66 1.33 2.99 -0.95
Vacuole -2.59 -2.62 -7.64 -3.95 -5.87 -2.80 -3.21 -6.77 -4.02 -5.86 -3.54 -4.30 -9.91 -4.46 -7.93
Vacuole Periphery -3.76 -0.79 -3.73 -2.24 -3.60 -3.08 -1.25 -2.21 -0.19 -2.07 -3.88 -1.45 -4.31 -1.25 -4.10
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of the SF3a splicing factor complex; required for spliceosome assembly
Localization
Cell Percentages nucleus (100%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-4

Prp21

Prp21


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Prp21-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available