ORF
Human Ortholog
Description Putative protein of unknown function; localizes to endoplasmic reticulum and cytoplasm; predicted to encode a membrane transporter based on phylogenetic analysis; not an essential gene; YJR015W has a paralog, SNG1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.57 0.69 0.83 0.88 0.81 0.8 0.64 0.81 0.64 0.77 0.56 0.66 0.9 0.99 0.99 0.93 0.88 0.92 0.14 0.28 0.3 0.48 0.66 0.58
Endoplasmic Reticulum 0.32 0.23 0.07 0 0.1 0 0 0 0 0 0 0 0.09 0 0 0 0.09 0.06 0.63 0.42 0.3 0.27 0.08 0.08
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.16 0.08 0.1 0.16 0.18 0.25 0.45 0.34 0.5 0.42 0.59 0.5 0 0 0 0 0 0 0.09 0.15 0.23 0.11 0.11 0.12
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0.05 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 1 2 0 0 0 0 0 0 0 0 0 0 1 0 4 0 4 11 8 6 6 11 14
Bud 0 1 2 0 0 0 1 2 4 4 0 1 2 1 1 3 1 0 1 3 1 7 7 10
Bud Neck 0 0 0 0 0 0 0 0 0 3 1 1 0 0 0 5 5 1 2 2 1 5 5 11
Bud Site 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 0 0 0 1 0 1 0 2 0 2 2 6 4 1 7 14 9 2 5 2 4 13 16
Cytoplasm 106 169 96 43 110 64 107 160 87 130 51 67 312 508 594 491 422 298 32 88 42 126 254 238
Endoplasmic Reticulum 59 55 8 1 13 3 6 0 1 0 0 0 30 2 3 21 41 20 147 129 42 72 32 32
Endosome 1 2 1 1 0 0 0 1 0 0 0 0 1 0 1 4 9 3 2 3 2 1 1 4
Golgi 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 2 3 0 0 3 1
Mitochondria 30 20 12 8 25 20 75 66 69 70 54 51 3 2 0 18 17 12 21 46 32 30 43 50
Nucleus 0 1 0 0 0 0 3 5 0 1 0 1 1 1 0 3 2 3 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1
Nucleolus 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 1 0 2 3 1 0 0 3 0 0 0 1 3 2 0 1 0 0 1 5
Vac/Vac Membrane 2 11 0 0 1 0 1 1 0 1 0 0 1 0 1 5 31 9 5 13 3 5 5 14
Unique Cell Count 185 244 116 49 136 80 166 197 137 168 91 101 346 513 598 527 477 324 233 310 141 266 389 412
Labelled Cell Count 204 262 122 53 151 87 199 239 165 209 108 126 356 520 601 564 549 362 233 310 141 266 389 412


Cytoplasm, Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.4 4.9 3.9 3.8 3.6 3.4 2.6 3.0 2.9 2.8 2.9 2.8 5.1 4.3 4.1 4.9 6.1 5.8 4.5 4.2 5.0
Std Deviation (1e-4) 0.7 0.8 0.8 0.7 0.6 1.3 0.8 1.1 1.0 1.7 1.2 1.4 1.0 1.1 1.3 1.3 1.6 1.3 1.1 1.3 1.5
Intensity Change (Log2) – – – -0.03 -0.1 -0.19 -0.58 -0.35 -0.41 -0.45 -0.39 -0.46 0.42 0.16 0.08 0.35 0.66 0.59 0.22 0.13 0.37

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.8 -0.4 -0.5 -3.4 -0.3 -3.4 -1.1 -4.2 -2.8 2.2 8.1 9.1 3.6 1.7 2.8
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0.6 0 0 -1.4 0.6 -0.3
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 -3.2 -3.0 -2.7
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 2.8 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6293 3.7588 3.7838 3.8687 3.1757 3.4461 2.112 2.5307 2.4482 2.3064 1.6582 2.1356 3.292 3.2037 3.1538 2.8488 2.1209 2.5331
Actin 0.0008 0.0004 0.0135 0.0034 0.0118 0.0006 0.0242 0.0043 0.0149 0.0042 0.0065 0.011 0.1952 0.0035 0.0926 0.021 0.0005 0.0035
Bud 0 0.0001 0.0009 0.0002 0.0005 0 0.0011 0.0001 0.001 0.0009 0.0002 0.0002 0.0009 0.0033 0.0046 0.0013 0 0
Bud Neck 0.0001 0.0002 0.0005 0.0006 0.0011 0.0028 0.002 0.0003 0.0032 0.0017 0.0004 0.0012 0.0265 0.0003 0.0102 0.0015 0.0003 0.0009
Bud Periphery 0.0001 0.0001 0.0015 0.0003 0.0018 0.0001 0.0028 0.0001 0.003 0.0018 0.0006 0.0006 0.0014 0.0148 0.0044 0.0028 0 0.0001
Bud Site 0.0003 0.0016 0.0118 0.0019 0.0015 0.0001 0.0077 0.0136 0.0123 0.004 0.0006 0.0002 0.0183 0.0077 0.0381 0.0015 0.0001 0.0001
Cell Periphery 0.0012 0.001 0.0014 0.0008 0.0013 0.0005 0.0017 0.0012 0.0028 0.0013 0.0009 0.0006 0.0016 0.0042 0.0035 0.003 0.0003 0.0011
Cytoplasm 0.2817 0.5406 0.361 0.3442 0.4701 0.5049 0.2382 0.3662 0.2993 0.3534 0.4526 0.4012 0.3817 0.4183 0.29 0.4549 0.5415 0.4661
Cytoplasmic Foci 0.0041 0.0082 0.0132 0.0171 0.0256 0.0091 0.0338 0.0092 0.025 0.012 0.0158 0.0186 0.054 0.0122 0.026 0.0094 0.0049 0.0146
Eisosomes 0.0003 0.0001 0.0004 0.0004 0.0008 0.0001 0.0009 0.0003 0.0006 0.0002 0.0003 0.0005 0.0028 0.0005 0.0006 0.0005 0.0002 0.0002
Endoplasmic Reticulum 0.0979 0.048 0.0882 0.0781 0.0544 0.0515 0.1151 0.0624 0.1267 0.1568 0.0583 0.0604 0.1106 0.0373 0.2097 0.14 0.116 0.1293
Endosome 0.0088 0.0074 0.0114 0.0324 0.0122 0.0061 0.0295 0.0048 0.02 0.0168 0.0075 0.0093 0.0439 0.0022 0.016 0.0372 0.0041 0.0061
Golgi 0.0004 0.0004 0.0033 0.0083 0.0029 0.0003 0.0092 0.0027 0.011 0.0047 0.0066 0.0025 0.0177 0.0008 0.0223 0.0204 0.0003 0.0006
Lipid Particles 0.0026 0.0012 0.0069 0.0172 0.0047 0.0015 0.0094 0.0028 0.0115 0.0091 0.0236 0.0042 0.0253 0.0042 0.0214 0.0035 0.0014 0.002
Mitochondria 0.0003 0.0002 0.0181 0.0127 0.0112 0.0003 0.0202 0.0003 0.0077 0.0052 0.0715 0.0088 0.0032 0.0008 0.0061 0.0267 0.0002 0.0002
None 0.5851 0.3798 0.4508 0.4694 0.3714 0.4071 0.4577 0.5249 0.4453 0.4041 0.3167 0.4671 0.0691 0.4823 0.1824 0.2533 0.325 0.3701
Nuclear Periphery 0.0089 0.0034 0.008 0.0031 0.0086 0.0038 0.0073 0.0017 0.0032 0.0055 0.0018 0.0025 0.0098 0.0015 0.0031 0.0085 0.0023 0.0013
Nucleolus 0.0002 0.0002 0.0003 0.0003 0.0005 0.0001 0.0007 0.0001 0.0002 0.0003 0.0002 0.0002 0.0008 0.0004 0.0005 0.0005 0 0.0001
Nucleus 0.0024 0.0023 0.0021 0.0015 0.0041 0.0079 0.0072 0.001 0.0011 0.0022 0.0008 0.0016 0.0038 0.0013 0.0014 0.0028 0.0011 0.0008
Peroxisomes 0.0001 0.0001 0.0015 0.0014 0.0007 0.0001 0.021 0.0018 0.0062 0.0084 0.0318 0.0063 0.0126 0.0003 0.0611 0.0004 0 0.0004
Punctate Nuclear 0.0007 0.001 0.0021 0.0012 0.0079 0.0009 0.0026 0.0007 0.001 0.0022 0.0011 0.001 0.0125 0.0018 0.003 0.0024 0.0004 0.0005
Vacuole 0.0035 0.0035 0.0027 0.0044 0.0054 0.0021 0.0063 0.0016 0.0034 0.0038 0.0017 0.0017 0.0075 0.0021 0.0026 0.0057 0.0014 0.0018
Vacuole Periphery 0.0004 0.0003 0.0004 0.001 0.0016 0.0002 0.0012 0.0001 0.0004 0.0012 0.0005 0.0003 0.0009 0.0002 0.0004 0.0027 0.0001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 68.378 69.4903 63.9785 71.1636 60.6587 51.0752 77.2552 75.3041 61.3115 69.7598
Translational Efficiency 1.1215 1.3575 1.2733 0.9993 1.1505 1.6393 1.1959 0.9677 1.1483 1.2312

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2015 944 325 1045 1861 1442 1311 2442 3876 2386 1636 3487

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 683.71 780.00 947.24 1063.45 723.73 784.60 961.17 1155.22 702.92 782.78 958.40 1127.72
Standard Deviation 79.37 127.17 101.10 190.79 83.57 100.88 129.82 202.80 83.83 112.05 124.77 203.66
Intensity Change Log 2 — 0.190090 0.470345 0.637296 — 0.116506 0.409340 0.674644 — 0.152720 0.439298 0.656622

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000136 0.001504 0.000591 0.006241 0.000234 0.000727 0.000427 0.007302 0.000183 0.001034 0.000459 0.006984
Bud Neck 0.012869 0.018778 0.003089 0.007329 0.012544 0.016950 0.004507 0.012802 0.012713 0.017673 0.004225 0.011162
Bud Site 0.003349 0.011249 0.002866 0.034832 0.002402 0.008752 0.008557 0.036945 0.002894 0.009740 0.007426 0.036312
Cell Periphery 0.000395 0.000615 0.000675 0.004958 0.000352 0.000467 0.000372 0.003468 0.000375 0.000526 0.000433 0.003914
Cytoplasm 0.438336 0.305228 0.239372 0.143379 0.384615 0.342541 0.443871 0.261262 0.412542 0.327779 0.403247 0.225934
Cytoplasmic Foci 0.195035 0.250860 0.060702 0.017724 0.212036 0.236186 0.051980 0.024184 0.203198 0.241992 0.053713 0.022248
Eisosomes 0.000474 0.000772 0.000209 0.000522 0.000612 0.000630 0.000111 0.000733 0.000540 0.000686 0.000131 0.000670
Endoplasmic Reticulum 0.035344 0.082830 0.080360 0.622554 0.051793 0.079016 0.079167 0.373943 0.043242 0.080525 0.079404 0.448448
Endosome 0.013688 0.036421 0.017312 0.008803 0.013580 0.027026 0.011137 0.013676 0.013636 0.030743 0.012364 0.012215
Golgi 0.004596 0.015348 0.000319 0.003219 0.008701 0.014166 0.000808 0.004178 0.006567 0.014634 0.000711 0.003890
Lipid Particles 0.053853 0.061240 0.024747 0.023217 0.070766 0.072573 0.016203 0.025375 0.061973 0.068089 0.017901 0.024728
Mitochondria 0.005347 0.009855 0.000481 0.003774 0.008262 0.009925 0.000539 0.004513 0.006746 0.009897 0.000528 0.004291
Mitotic Spindle 0.000262 0.003492 0.000333 0.005358 0.000127 0.003723 0.002044 0.012890 0.000197 0.003632 0.001704 0.010633
None 0.005368 0.002661 0.001356 0.000756 0.003241 0.002463 0.003694 0.002467 0.004347 0.002541 0.003230 0.001954
Nuclear Periphery 0.002832 0.005234 0.024754 0.001186 0.003934 0.002923 0.018276 0.005963 0.003361 0.003837 0.019563 0.004531
Nuclear Periphery Foci 0.002317 0.008115 0.058035 0.014932 0.002513 0.004629 0.043745 0.024135 0.002411 0.006008 0.046584 0.021377
Nucleolus 0.002351 0.001496 0.001136 0.000086 0.000793 0.000922 0.000474 0.000444 0.001603 0.001149 0.000605 0.000337
Nucleus 0.163932 0.068840 0.316493 0.033500 0.160591 0.081604 0.153715 0.072973 0.162328 0.076554 0.186052 0.061143
Peroxisomes 0.003531 0.011676 0.001031 0.000832 0.005381 0.008945 0.000937 0.001615 0.004419 0.010025 0.000956 0.001380
Vacuole 0.054829 0.099890 0.165704 0.065680 0.055990 0.082756 0.159073 0.108240 0.055387 0.089535 0.160390 0.095485
Vacuole Periphery 0.001154 0.003896 0.000434 0.001117 0.001534 0.003076 0.000362 0.002894 0.001336 0.003400 0.000376 0.002362

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.52 -6.33 -8.00 -5.86 -7.30 -3.40 -3.24 -8.68 -7.92 -8.37 -5.73 -5.65 -11.21 -9.48 -10.64
Bud Neck -2.53 9.11 3.66 4.80 -4.88 -2.42 5.82 -0.44 2.44 -8.73 -3.51 8.83 1.21 4.67 -9.20
Bud Site -5.79 0.27 -9.35 -6.71 -9.44 -5.88 -4.05 -15.57 -11.53 -10.98 -8.01 -3.71 -17.98 -13.24 -13.55
Cell Periphery -3.47 -5.62 -7.64 -7.22 -7.11 -3.51 0.05 -7.60 -7.25 -7.59 -4.69 -1.70 -10.55 -10.00 -10.39
Cytoplasm 14.17 16.25 33.04 14.09 5.64 5.10 -4.49 14.38 7.93 15.87 13.72 3.04 30.08 13.11 17.99
Cytoplasmic Foci -7.46 23.86 42.94 35.07 8.80 -3.65 34.46 42.73 40.87 10.55 -7.92 44.68 60.39 53.68 13.69
Eisosomes -2.87 10.35 -0.71 2.35 -6.38 -0.28 13.44 -0.49 -0.30 -6.88 -2.78 18.94 -1.16 0.97 -8.41
Endoplasmic Reticulum -7.20 -4.75 -40.65 -34.21 -33.09 -4.71 -3.06 -32.05 -26.41 -28.21 -8.69 -6.05 -48.75 -39.85 -41.02
Endosome -10.24 -2.69 5.42 12.68 6.90 -8.68 3.51 0.99 9.47 -2.68 -13.31 2.62 3.31 15.17 0.61
Golgi -7.09 13.26 2.82 7.96 -5.24 -4.75 11.11 7.22 10.05 -4.99 -8.97 12.79 7.02 12.68 -6.03
Lipid Particles -1.91 10.53 10.09 10.36 0.05 -0.43 21.27 16.72 14.55 -5.85 -2.16 24.48 19.08 17.92 -5.33
Mitochondria -2.89 7.18 1.39 3.49 -2.56 -1.15 7.72 3.94 5.39 -10.16 -3.07 10.41 3.88 6.41 -7.91
Mitotic Spindle -2.39 -0.56 -3.13 -0.84 -3.08 -3.26 -3.50 -8.48 -4.83 -6.44 -4.01 -3.43 -8.97 -4.75 -6.83
None 2.82 4.91 6.22 3.09 1.32 0.75 -0.06 1.17 0.34 1.12 2.54 1.66 4.18 1.39 1.46
Nuclear Periphery -2.03 -6.75 4.89 3.43 7.32 1.75 -8.45 -2.92 -4.69 7.01 -0.83 -10.97 -2.60 -1.12 9.88
Nuclear Periphery Foci -4.98 -10.82 -10.78 -4.17 7.88 -3.13 -16.30 -14.25 -11.83 6.45 -5.86 -19.46 -17.11 -12.01 9.62
Nucleolus 1.02 3.33 6.75 3.89 8.23 -1.38 4.27 3.06 3.43 -0.36 1.32 5.39 6.61 4.66 2.97
Nucleus 20.72 -10.61 27.44 5.82 18.63 17.27 0.60 17.43 -0.43 14.15 26.62 -5.08 28.84 1.82 22.20
Peroxisomes -6.82 10.95 11.47 9.20 1.59 -4.07 11.77 12.11 8.95 -2.15 -7.95 13.08 15.22 12.70 -1.73
Vacuole -9.16 -13.15 -7.40 0.13 7.40 -7.40 -21.62 -20.58 -12.79 5.92 -11.70 -25.25 -21.78 -10.39 9.04
Vacuole Periphery -6.45 8.14 0.33 4.98 -1.52 -5.56 10.51 -2.16 1.31 -5.17 -8.75 13.15 -2.16 3.59 -5.38
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; localizes to endoplasmic reticulum and cytoplasm; predicted to encode a membrane transporter based on phylogenetic analysis; not an essential gene; YJR015W has a paralog, SNG1, that arose from the whole genome duplication
Localization
Cell Percentages ER (48%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

YJR015W

YJR015W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yjr015w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available