Standard name
Human Ortholog
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity; plays a role in determining prion variants
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.99 0.97 0.95 0.83 0.75 0.75 0.72 0.64 0.57 0.59 1.0 0.99 0.98 0.89 0.94 0.94 0.98 0.96 0.97 0.97 0.95 0.96
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0.07 0.24 0.28 0.24 0.29 0.41 0.48 0.44 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.09 0.08 0.07 0.14 0.13 0.11 0 0 0 0.14 0.09 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Bud 1 0 0 0 1 4 14 6 8 16 13 5 0 0 0 0 1 1 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 2 11 4 2 7 13 8 11 10 6 13 1 2 3 12 15 7 0 0 0 0 0 0
Cytoplasm 187 383 496 398 486 508 626 538 378 474 313 402 482 414 485 563 682 466 182 370 476 330 324 364
Endoplasmic Reticulum 0 5 1 2 0 4 8 10 13 7 6 11 0 1 3 15 17 12 0 0 6 0 1 0
Endosome 0 0 0 0 0 1 0 0 0 1 1 0 0 0 0 1 1 2 0 0 0 1 1 2
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 1
Mitochondria 2 2 3 25 34 149 236 175 153 301 262 298 0 0 0 4 2 0 0 2 1 1 0 2
Nucleus 0 1 0 0 2 5 6 12 6 7 10 15 2 0 1 11 7 11 0 4 0 2 3 0
Nuclear Periphery 0 0 0 1 0 3 1 5 3 4 0 8 0 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
Vac/Vac Membrane 1 0 4 12 12 27 79 59 35 106 69 77 0 11 12 91 66 32 0 3 1 3 1 1
Unique Cell Count 189 388 502 412 511 609 835 719 526 735 549 678 482 418 495 635 728 495 186 387 491 342 340 379
Labelled Cell Count 191 393 515 442 537 710 983 813 607 927 680 829 485 429 504 698 791 532 186 387 491 342 340 379


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.5 7.8 7.5 6.8 6.7 6.0 5.7 5.7 5.6 5.4 5.2 5.1 9.1 8.7 8.4 11.9 11.3 10.5 9.4 9.4 10.3
Std Deviation (1e-4) 1.0 1.1 1.0 0.9 1.2 1.1 1.0 1.1 0.9 1.0 1.2 1.1 1.2 1.1 1.1 2.2 1.9 2.3 1.4 1.4 1.4
Intensity Change (Log2) – – – -0.14 -0.16 -0.31 -0.38 -0.38 -0.41 -0.47 -0.53 -0.54 0.28 0.23 0.17 0.67 0.59 0.49 0.33 0.33 0.46

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 2.9 0 0 3.3 3.5 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.4 -2.5 -1.4 -0.8 -1.5 -0.1 -1.1 -1.4 -0.3 -2.8 -2.2 -2.1 -0.4 -0.2 -0.9
Cytoplasm -2.3 -3.4 -8.7 -11.5 -11.4 -12.1 -14.4 -16.1 -15.7 2.4 0.3 -1.0 -6.7 -4.4 -4.0
Endoplasmic Reticulum 0 0 0 0 0 3.1 0 0 2.4 0 0 0 3.1 3.1 3.1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.8 5.1 11.5 12.8 11.6 12.7 16.2 17.6 16.9 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 3.4 0 0 0 0 0 3.4
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 2.4 2.0 3.7 6.4 5.8 4.9 8.3 7.5 7.1 0 2.2 2.0 8.2 6.2 4.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5865 5.0619 4.8276 4.844 4.2415 4.6228 3.2635 4.6797 4.4369 3.6635 3.514 4.2663 2.8416 4.1891 3.7322 3.4262 3.3395 3.3574
Actin 0.0325 0.0054 0.0181 0.0519 0.003 0.0047 0.0236 0.0002 0.0006 0.0651 0.0001 0.0083 0.0128 0.0011 0.0015 0.0002 0.0038 0.0027
Bud 0.0006 0.0037 0.0017 0.0004 0.0004 0.0003 0.0009 0.0002 0.0002 0.0018 0.0001 0.0003 0.0007 0.0004 0.001 0.0001 0.0005 0.0002
Bud Neck 0.0023 0.0002 0.0026 0.0009 0.0005 0.0009 0.002 0.0001 0.0003 0.0007 0.0003 0.0031 0.0008 0.0003 0.0004 0.0002 0.001 0.0005
Bud Periphery 0.0015 0.002 0.0019 0.0005 0.0004 0.0002 0.0009 0 0.0001 0.0021 0 0.0003 0.0009 0.0003 0.0011 0 0.0006 0.0005
Bud Site 0.0056 0.0043 0.0094 0.0012 0.0004 0.0004 0.0061 0.0004 0.0004 0.0091 0.0001 0.0007 0.0033 0.0058 0.0018 0 0.0017 0.0001
Cell Periphery 0.001 0.0003 0.0004 0.0006 0 0.0001 0.0002 0 0 0.0002 0 0.0001 0.0001 0 0.0001 0 0.0001 0
Cytoplasm 0.768 0.9348 0.8551 0.8894 0.7803 0.8979 0.7887 0.9528 0.9393 0.8291 0.9797 0.884 0.8186 0.9577 0.9129 0.9872 0.6625 0.9474
Cytoplasmic Foci 0.037 0.0062 0.0097 0.0048 0.0453 0.0113 0.0191 0.0045 0.0053 0.0201 0.0039 0.0262 0.0158 0.0052 0.0133 0.0017 0.0511 0.0046
Eisosomes 0.0011 0.0001 0.0001 0.0004 0 0 0.0002 0 0 0.0003 0 0.0001 0.0001 0 0 0 0.0001 0
Endoplasmic Reticulum 0.006 0.0015 0.0039 0.0035 0.0032 0.0019 0.0063 0.0018 0.0017 0.0037 0.0017 0.0028 0.0048 0.0011 0.0025 0.0022 0.0021 0.0015
Endosome 0.0149 0.0027 0.0188 0.0031 0.0705 0.006 0.0302 0.0052 0.0082 0.0252 0.0031 0.0187 0.0171 0.0035 0.0176 0.0006 0.1356 0.0072
Golgi 0.0069 0.0011 0.006 0.0022 0.0242 0.0041 0.0061 0.0002 0.0007 0.0055 0.0001 0.0066 0.0077 0.0021 0.0109 0 0.0649 0.0033
Lipid Particles 0.0125 0.0006 0.0022 0.0016 0.0053 0.008 0.0052 0 0.0007 0.003 0 0.0058 0.0106 0.0001 0.0012 0 0.0207 0.0006
Mitochondria 0.0114 0.0013 0.0091 0.0008 0.0036 0.0011 0.0104 0.0002 0.0025 0.0073 0.0001 0.0042 0.0099 0.0015 0.0079 0.0001 0.0234 0.0019
None 0.0657 0.0302 0.0457 0.0134 0.039 0.0466 0.0527 0.0293 0.0255 0.0119 0.0048 0.0099 0.0766 0.0175 0.0125 0.0031 0.002 0.0107
Nuclear Periphery 0.0023 0.0008 0.0041 0.0031 0.0035 0.0023 0.0123 0.0007 0.0025 0.0019 0.001 0.0053 0.0019 0.0005 0.0012 0.0007 0.0022 0.0096
Nucleolus 0.0004 0.0001 0.0006 0.0007 0.0002 0.0005 0.0008 0 0.0005 0.0006 0 0.0005 0.0003 0 0.0001 0 0.0003 0.0001
Nucleus 0.0019 0.0017 0.0031 0.013 0.0035 0.005 0.0154 0.0024 0.0044 0.0038 0.0035 0.0046 0.0037 0.0015 0.0036 0.0031 0.0017 0.0037
Peroxisomes 0.0246 0.0005 0.0027 0.0004 0.0085 0.0024 0.0045 0.0001 0.0003 0.0016 0 0.0075 0.0058 0.0003 0.0079 0 0.0168 0.0015
Punctate Nuclear 0.0016 0.0019 0.003 0.001 0.0054 0.0056 0.0093 0.0003 0.0042 0.0015 0.0002 0.009 0.004 0.0004 0.0004 0.0001 0.0018 0.0004
Vacuole 0.0019 0.0006 0.0014 0.0066 0.0019 0.0005 0.0042 0.0011 0.0016 0.0044 0.0011 0.0012 0.0035 0.0006 0.0015 0.0004 0.0036 0.0013
Vacuole Periphery 0.0005 0.0001 0.0005 0.0004 0.0009 0.0002 0.0011 0.0002 0.0008 0.001 0.0002 0.0008 0.001 0.0002 0.0007 0.0001 0.0035 0.0021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 23.3377 14.1865 23.5309 26.9633 30.8635 21.4588 23.6253 26.1961 25.2675 27.7927
Translational Efficiency 1.8553 3.115 1.6708 1.5829 1.3571 1.7121 1.7504 1.1628 1.3352 1.6387

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1295 580 2503 1203 1511 1786 135 1079 2806 2366 2638 2282

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 909.66 1016.38 1141.25 1114.43 909.93 962.23 1319.36 1089.84 909.81 975.50 1150.36 1102.80
Standard Deviation 117.35 140.35 136.20 152.31 119.08 133.79 123.48 162.36 118.28 137.42 141.15 157.62
Intensity Change Log 2 — 0.160041 0.327216 0.292907 — 0.080626 0.536011 0.260289 — 0.120874 0.435403 0.276688

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000158 0.000296 0.000182 0.001070 0.000190 0.000269 0.000703 0.000796 0.000175 0.000276 0.000208 0.000940
Bud Neck 0.001615 0.001267 0.001507 0.001461 0.000953 0.001701 0.001981 0.001640 0.001258 0.001595 0.001531 0.001546
Bud Site 0.005182 0.011274 0.006367 0.016396 0.003876 0.007419 0.010229 0.010513 0.004478 0.008364 0.006565 0.013614
Cell Periphery 0.000087 0.000078 0.000038 0.000133 0.000108 0.000099 0.000309 0.000068 0.000098 0.000094 0.000052 0.000102
Cytoplasm 0.727926 0.780200 0.798017 0.747674 0.778386 0.774509 0.501849 0.797118 0.755098 0.775905 0.782861 0.771053
Cytoplasmic Foci 0.138899 0.112535 0.012430 0.023631 0.106151 0.104418 0.039891 0.023951 0.121264 0.106408 0.013835 0.023782
Eisosomes 0.000028 0.000015 0.000007 0.000013 0.000023 0.000019 0.000063 0.000013 0.000025 0.000018 0.000010 0.000013
Endoplasmic Reticulum 0.001267 0.000815 0.000466 0.001881 0.002086 0.000480 0.003759 0.000564 0.001708 0.000562 0.000635 0.001258
Endosome 0.007550 0.007150 0.000916 0.006439 0.004702 0.005765 0.014484 0.005884 0.006017 0.006105 0.001610 0.006177
Golgi 0.002285 0.003123 0.000091 0.002353 0.001433 0.001834 0.000482 0.005974 0.001826 0.002150 0.000111 0.004065
Lipid Particles 0.001515 0.000723 0.000374 0.001671 0.002065 0.000826 0.003539 0.001149 0.001812 0.000801 0.000536 0.001424
Mitochondria 0.003867 0.002132 0.000266 0.003796 0.001192 0.000394 0.000106 0.001231 0.002427 0.000820 0.000258 0.002583
Mitotic Spindle 0.002165 0.004583 0.004775 0.016670 0.001841 0.004702 0.001147 0.015668 0.001991 0.004673 0.004589 0.016196
None 0.001342 0.002434 0.004217 0.004035 0.003577 0.002434 0.001049 0.004587 0.002546 0.002434 0.004054 0.004296
Nuclear Periphery 0.000118 0.000099 0.000392 0.000229 0.000164 0.000083 0.000951 0.000272 0.000142 0.000087 0.000421 0.000249
Nuclear Periphery Foci 0.001852 0.002242 0.001269 0.003672 0.002419 0.001088 0.025295 0.003202 0.002158 0.001371 0.002499 0.003450
Nucleolus 0.000186 0.000214 0.000121 0.000102 0.000207 0.000222 0.000159 0.000151 0.000198 0.000220 0.000123 0.000125
Nucleus 0.040269 0.026828 0.120907 0.065216 0.056822 0.033253 0.081600 0.057327 0.049183 0.031678 0.118895 0.061486
Peroxisomes 0.000597 0.001131 0.000209 0.000614 0.000472 0.000804 0.000328 0.001172 0.000530 0.000884 0.000215 0.000878
Vacuole 0.062234 0.042031 0.047323 0.100251 0.032615 0.059154 0.311711 0.066919 0.046285 0.054956 0.060853 0.084490
Vacuole Periphery 0.000858 0.000830 0.000128 0.002692 0.000718 0.000527 0.000366 0.001802 0.000782 0.000601 0.000140 0.002271

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.16 -0.92 -3.32 -2.29 -2.95 -0.80 -7.59 -2.71 -1.55 1.12 -1.37 -1.10 -4.25 -2.54 -3.51
Bud Neck 1.73 -0.55 0.72 -1.38 1.43 -3.64 -4.90 -1.61 1.27 2.06 -1.99 -2.89 -1.03 1.01 1.80
Bud Site -4.18 -0.59 -4.26 0.23 -3.72 -4.67 -6.20 -4.66 -0.59 1.08 -5.54 -1.93 -6.26 -1.19 -3.63
Cell Periphery 0.90 8.35 -1.39 -1.86 -5.45 0.29 -6.04 5.37 2.98 7.85 -0.01 9.87 1.56 1.08 -5.24
Cytoplasm -4.62 0.08 8.75 11.63 10.01 1.08 15.12 8.63 7.71 -11.36 -3.05 7.29 12.81 15.00 6.05
Cytoplasmic Foci 3.60 28.82 26.52 15.09 -7.74 0.34 17.02 22.19 23.24 2.77 3.76 38.37 34.49 28.62 -9.47
Eisosomes 6.46 10.83 6.84 -0.47 -7.01 2.36 -9.26 5.62 3.21 11.23 5.55 11.85 8.83 2.82 -3.76
Endoplasmic Reticulum 2.31 4.47 1.43 -0.13 -0.85 5.19 -2.71 5.65 1.27 9.94 6.15 5.32 4.90 -0.39 0.97
Endosome 0.46 12.75 7.21 4.21 -3.04 -1.77 -4.20 3.52 4.73 5.68 -0.01 13.91 7.41 6.70 -2.04
Golgi -0.73 3.64 2.45 2.53 -3.32 -0.71 4.06 -0.30 0.08 -1.57 -0.57 5.54 1.19 1.58 -2.57
Lipid Particles 5.13 7.64 -0.03 -3.87 -5.10 2.16 -1.30 1.87 -0.66 5.16 3.18 3.56 1.66 -3.11 -4.21
Mitochondria 0.87 2.34 1.66 0.66 -1.30 1.74 2.46 1.66 0.03 -1.43 1.98 2.89 2.02 0.08 -1.42
Mitotic Spindle -1.28 -3.23 -4.13 -2.39 -2.18 -2.03 1.03 -3.12 -1.26 -3.78 -2.32 -3.99 -5.22 -2.65 -2.16
None -2.19 -12.34 -3.55 -0.67 2.53 1.73 4.13 0.52 -1.76 -5.67 0.31 -3.67 -1.31 -1.48 2.49
Nuclear Periphery 0.90 -25.71 -15.60 -12.09 9.61 2.87 -11.34 -3.21 -7.16 9.56 3.39 -21.97 -9.54 -15.35 12.99
Nuclear Periphery Foci -1.69 1.23 -5.71 -3.13 -6.87 7.00 -8.76 -1.53 -8.28 8.56 5.51 -2.27 -4.98 -9.96 -2.15
Nucleolus -0.82 2.51 4.15 2.80 2.76 -0.38 1.82 2.24 3.01 0.87 -0.78 2.36 3.44 3.83 2.47
Nucleus 6.00 -34.80 -13.64 -17.58 18.27 10.25 -3.17 -4.49 -13.65 1.59 10.64 -32.77 -12.35 -21.35 21.85
Peroxisomes -2.20 4.85 3.61 3.41 -0.84 -2.13 1.61 0.05 1.88 -1.17 -2.94 3.55 1.54 3.96 -1.57
Vacuole 4.49 -6.31 -20.80 -22.66 -17.23 -10.84 -15.90 -21.27 -16.23 9.23 -4.17 -16.04 -29.95 -27.26 -15.85
Vacuole Periphery 0.23 6.68 0.19 0.04 -2.51 1.41 3.60 0.51 -0.03 -0.71 1.78 7.89 0.47 -0.35 -2.48
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Peptidyl-prolyl cis-trans isomerase (cyclophilin); catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity; plays a role in determining prion variants
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Cpr7

Cpr7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cpr7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available