Standard name
Human Ortholog
Description Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.62 0.81 0.54 0.7 0.61 0.66 0.6 0.49 0.55 0.54 0.49 0.42 0.85 0.9 0.78 0.82 0.79 0.7 0.15 0.2 0.09 0.1 0.11 0
Endoplasmic Reticulum 0.07 0 0 0 0 0 0 0 0 0 0 0 0.12 0 0.08 0.06 0.08 0.07 0 0 0 0 0 0
Endosome 0.15 0 0.3 0.18 0.22 0 0.07 0.11 0 0 0 0 0 0 0 0.07 0.12 0.17 0.33 0.27 0.38 0.29 0.22 0.29
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.05 0.1
Mitochondria 0 0.08 0.06 0.16 0.15 0.5 0.48 0.53 0.64 0.65 0.69 0.71 0 0 0 0.07 0.05 0.07 0.11 0.09 0.15 0.22 0.13 0.13
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.21 0.07 0.16 0.09 0.16 0.07 0.08 0.07 0 0 0 0 0 0.1 0.15 0.06 0.1 0.15 0.31 0.32 0.24 0.28 0.41 0.33
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 17 1 0 0 0 0 1 2 1 2 1 5 0 0 0 5 8 2 7 3 5 0 2 4
Bud 5 2 4 2 5 3 4 10 6 18 12 7 0 0 1 4 4 2 2 3 0 3 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 1 3 2 3 2 2 2 3 3 1 0 0 3 0 2 0 0 0 0 0 0
Cytoplasm 325 199 166 181 225 228 302 215 195 249 169 157 115 26 74 563 394 312 92 58 31 15 23 5
Endoplasmic Reticulum 36 9 3 5 2 3 3 5 11 4 3 11 16 0 8 44 40 31 8 7 13 2 8 7
Endosome 81 9 93 48 81 10 37 50 1 11 3 4 3 1 1 51 62 75 211 80 132 43 45 49
Golgi 2 2 1 0 1 0 0 0 0 0 0 2 0 0 0 0 0 2 26 11 16 2 10 16
Mitochondria 12 19 18 42 54 174 240 235 227 301 240 264 0 0 0 50 25 33 70 25 53 31 26 22
Nucleus 1 0 0 0 1 3 0 3 1 2 1 0 0 0 2 0 3 1 0 1 0 0 1 0
Nuclear Periphery 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 4 1 3 0 0 0
Nucleolus 1 0 0 0 0 0 2 2 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0
Peroxisomes 0 0 5 1 2 0 2 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0
SpindlePole 8 0 12 3 2 1 1 3 0 3 1 2 0 0 0 14 6 13 7 1 2 1 1 0
Vac/Vac Membrane 109 17 48 23 58 25 42 29 9 19 15 16 6 3 14 38 51 65 195 94 83 41 84 54
Unique Cell Count 524 245 306 260 369 346 503 442 355 464 347 372 136 29 95 683 497 444 634 296 350 147 206 167
Labelled Cell Count 597 258 352 306 434 449 637 557 454 612 449 472 141 30 100 774 594 541 634 296 350 147 206 167


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.0 6.4 5.4 5.2 5.5 4.6 4.6 4.9 4.5 4.4 4.4 4.6 6.7 6.9 7.1 5.6 6.1 6.8 6.6 7.3 8.4
Std Deviation (1e-4) 0.6 0.9 1.4 1.3 1.9 1.2 1.2 1.4 1.2 1.1 1.1 1.0 0.8 0.6 1.2 1.1 1.2 1.5 1.3 1.4 2.5
Intensity Change (Log2) – – – -0.05 0.03 -0.23 -0.22 -0.13 -0.25 -0.29 -0.28 -0.22 0.32 0.36 0.4 0.05 0.18 0.34 0.3 0.43 0.65


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0.9 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 3.7 1.8 3.0 1.6 -1.5 0.2 -0.2 -1.4 -3.1 6.1 3.7 4.1 9.3 7.5 4.5
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 5.2 0 0 3.7 4.3 3.9
Endosome -3.3 -2.5 0 0 -6.5 0 0 0 0 -6.6 -3.1 -5.9 -9.4 -6.2 -4.4
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 4.0 3.7 0 0 13.4 0 0 0 0 -2.9 0 0 0.8 -0.5 0.8
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole -2.0 -3.1 0 0 -3.1 0 0 0 0 0 0 0 -1.7 -2.5 -0.7
Vacuole -2.4 0 -3.4 -3.2 -4.0 -6.0 -5.6 -4.9 -5.0 -3.3 0 -0.2 -5.2 -2.3 -0.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.9696 1.6954 1.4247 1.2315 0.7848 1.0452 3.3878 3.1157 3.2243 3.7484 3.0631 3.4436 2.4803 2.3515 2.8902 2.8989 2.4388 2.8594
Actin 0.0018 0.0003 0.0006 0.0002 0.0107 0.0003 0.0262 0.0005 0.0147 0.0388 0.0264 0.0018 0.0004 0.0001 0.0003 0.0005 0 0.0001
Bud 0.0011 0.0004 0.0004 0.0004 0.0004 0.0004 0.0015 0.0005 0.0006 0.0017 0.0002 0.0006 0.0002 0.0009 0.0009 0.0002 0.0002 0.0002
Bud Neck 0.0007 0.0002 0.0001 0.0004 0.0003 0.0007 0.0051 0.0002 0.0012 0.0006 0.0003 0.002 0.0002 0.0001 0.0021 0.0002 0.0002 0.0004
Bud Periphery 0.0007 0.0004 0.0003 0.0001 0.0002 0.0002 0.0027 0.0006 0.0007 0.0026 0.0002 0.0006 0.0001 0.0004 0.001 0.0001 0.0001 0.0003
Bud Site 0.0061 0.0024 0.0005 0.0004 0.0014 0.0005 0.0095 0.0014 0.0038 0.0021 0.0009 0.0012 0.0011 0.0004 0.0007 0.0003 0.0003 0.0001
Cell Periphery 0.0003 0.0004 0.0002 0.0001 0.0001 0.0001 0.0012 0.0002 0.0003 0.0004 0.0001 0.0001 0.0002 0.0001 0.0005 0.0001 0.0001 0.0002
Cytoplasm 0.0684 0.2755 0.2311 0.1789 0.2442 0.2787 0.1369 0.3046 0.2282 0.107 0.127 0.2416 0.0758 0.273 0.163 0.266 0.1458 0.2979
Cytoplasmic Foci 0.0669 0.0717 0.0848 0.1382 0.1063 0.1305 0.1276 0.1266 0.1357 0.0701 0.1063 0.1311 0.2129 0.0713 0.097 0.0773 0.0704 0.075
Eisosomes 0 0 0.0001 0 0.0001 0 0.0004 0.0001 0.0005 0.0003 0.0002 0 0 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0055 0.0092 0.015 0.0033 0.0091 0.0065 0.0079 0.0052 0.0052 0.0056 0.0026 0.0026 0.0073 0.0296 0.0077 0.0123 0.0022 0.0092
Endosome 0.5009 0.4239 0.4439 0.5006 0.4478 0.4624 0.4046 0.3615 0.3758 0.4463 0.53 0.4126 0.5737 0.3053 0.3542 0.4338 0.5046 0.4369
Golgi 0.0195 0.0111 0.0168 0.0214 0.0265 0.0227 0.0305 0.0183 0.0201 0.0134 0.016 0.0218 0.0598 0.0125 0.0492 0.0154 0.0488 0.0208
Lipid Particles 0.0247 0.004 0.0087 0.0172 0.0292 0.0048 0.0161 0.0066 0.0049 0.0476 0.0185 0.0101 0.0104 0.0154 0.0047 0.0074 0.0025 0.0013
Mitochondria 0.0127 0.0088 0.0136 0.0028 0.004 0.0081 0.0194 0.0049 0.0068 0.0075 0.0028 0.0105 0.0047 0.0092 0.0215 0.0034 0.0021 0.0181
None 0.0133 0.0723 0.1195 0.0177 0.0127 0.0308 0.1108 0.1192 0.1381 0.143 0.0484 0.1034 0.0214 0.1264 0.1711 0.1213 0.19 0.0989
Nuclear Periphery 0.0469 0.0047 0.0042 0.003 0.0071 0.0026 0.0075 0.0018 0.0018 0.0018 0.0017 0.0072 0.002 0.0057 0.0023 0.0057 0.0016 0.0018
Nucleolus 0.0065 0.0006 0.0003 0.0002 0.0002 0.0002 0.0007 0.0002 0.0003 0.0007 0.0001 0.0002 0.0002 0.0001 0.0006 0.0003 0.0002 0
Nucleus 0.122 0.0021 0.0015 0.0015 0.0031 0.002 0.0023 0.0014 0.0012 0.0021 0.0006 0.0013 0.0006 0.0011 0.0014 0.0018 0.0012 0.0008
Peroxisomes 0.0041 0.0008 0.0024 0.0046 0.0026 0.0018 0.0159 0.0013 0.0152 0.0044 0.0597 0.0135 0.002 0.0023 0.0045 0.0013 0.0011 0.0007
Punctate Nuclear 0.0577 0.0008 0.0011 0.0011 0.0012 0.0016 0.004 0.0004 0.0014 0.0007 0.0039 0.0008 0.0009 0.0002 0.0005 0.0013 0.0005 0.0002
Vacuole 0.0312 0.0928 0.0407 0.0863 0.0768 0.0347 0.0598 0.0366 0.0361 0.0809 0.0421 0.0261 0.02 0.1062 0.0984 0.0422 0.0223 0.0247
Vacuole Periphery 0.0089 0.0176 0.0142 0.0218 0.0161 0.0104 0.0093 0.0076 0.0076 0.0225 0.0121 0.0109 0.006 0.0397 0.0186 0.0091 0.0061 0.0125

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.3232 7.9898 8.6237 13.018 8.0766 10.8276 11.3221 13.0528 13.7131 14.7592
Translational Efficiency 0.3201 0.3946 0.5157 0.4068 0.4912 0.3823 0.4431 0.3047 0.3488 0.4241

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
298 1344 674 1185 1078 1363 226 1719 1376 2707 900 2904

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 860.93 697.75 1030.06 912.88 628.50 817.12 981.83 913.04 678.84 757.85 1017.95 912.97
Standard Deviation 130.24 95.59 124.84 155.95 82.75 102.18 111.50 123.50 134.92 115.57 123.41 137.67
Intensity Change Log 2 — -0.303186 0.258761 0.084529 — 0.378635 0.643561 0.538765 — 0.024434 0.433791 0.293863

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002394 0.000302 0.000488 0.003289 0.001353 0.000574 0.001013 0.001505 0.001578 0.000439 0.000620 0.002233
Bud Neck 0.009688 0.008539 0.002152 0.004628 0.014780 0.009363 0.008135 0.005749 0.013677 0.008954 0.003654 0.005292
Bud Site 0.037675 0.012968 0.017036 0.046757 0.011481 0.010867 0.016332 0.033351 0.017154 0.011910 0.016859 0.038822
Cell Periphery 0.000161 0.000062 0.000052 0.000086 0.000465 0.000098 0.000065 0.000050 0.000399 0.000080 0.000055 0.000065
Cytoplasm 0.069354 0.120449* 0.036934 0.116235* 0.097315 0.092079 0.064629 0.133572* 0.091259 0.106165* 0.043888 0.126497*
Cytoplasmic Foci 0.232013* 0.422343* 0.259983* 0.195162* 0.334916* 0.375527* 0.170793 0.259675* 0.312631* 0.398771* 0.237586* 0.233350*
Eisosomes 0.000070 0.000091 0.000017 0.000027 0.001134 0.000170 0.000050 0.000029 0.000904 0.000130 0.000025 0.000028
Endoplasmic Reticulum 0.001478 0.001570 0.001851 0.000992 0.002336 0.002125 0.003108 0.001161 0.002150 0.001850 0.002166 0.001092
Endosome 0.328530* 0.197960 0.236227* 0.190189 0.097331 0.204124* 0.243880* 0.211043* 0.147402 0.201064* 0.238149* 0.202533*
Golgi 0.042526 0.058356 0.095916 0.045162 0.210071* 0.097728 0.010484 0.041769 0.173786* 0.078180 0.074463 0.043154
Lipid Particles 0.004384 0.017818 0.003245 0.003089 0.028970 0.015827 0.008110 0.003259 0.023645 0.016816 0.004467 0.003190
Mitochondria 0.015092 0.017964 0.001383 0.002894 0.142002* 0.035021 0.000917 0.004766 0.114517* 0.026552 0.001266 0.004002
Mitotic Spindle 0.010727 0.011421 0.025304 0.014491 0.000770 0.005580 0.015487 0.014160 0.002926 0.008480 0.022839 0.014295
None 0.000055 0.001252 0.000075 0.000084 0.001364 0.000238 0.000302 0.000107 0.001081 0.000741 0.000132 0.000098
Nuclear Periphery 0.000220 0.000547 0.001049 0.000267 0.000076 0.000155 0.001866 0.000208 0.000107 0.000350 0.001254 0.000232
Nuclear Periphery Foci 0.000684 0.001873 0.004181 0.001875 0.000162 0.000259 0.008483 0.001147 0.000275 0.001060 0.005262 0.001444
Nucleolus 0.000400 0.002389 0.000583 0.000415 0.000526 0.000402 0.003442 0.000306 0.000498 0.001389 0.001301 0.000350
Nucleus 0.002627 0.006652 0.001544 0.001762 0.005021 0.003361 0.022621 0.002406 0.004503 0.004995 0.006837 0.002143
Peroxisomes 0.025614 0.016212 0.006015 0.012053 0.021222 0.009753 0.020563 0.017309 0.022173 0.012960 0.009668 0.015164
Vacuole 0.202870* 0.086673 0.244600* 0.330916* 0.013441 0.107173 0.382502* 0.248965* 0.054466 0.096995 0.279229* 0.282406*
Vacuole Periphery 0.013440 0.014559 0.061366 0.029625 0.015264 0.029577 0.017219 0.019463 0.014869 0.022121 0.050280 0.023609

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.80 2.52 -0.57 -2.97 -2.75 2.32 0.67 -0.26 -2.02 -0.77 4.12 3.51 -1.07 -3.69 -3.27
Bud Neck 0.57 4.03 2.56 6.07 -7.17 3.48 3.57 6.14 4.54 2.57 3.79 8.15 6.85 7.09 -4.38
Bud Site 4.63 3.67 -1.36 -10.84 -8.40 0.47 -2.99 -10.96 -11.36 -6.30 3.46 -0.08 -10.10 -15.55 -9.90
Cell Periphery 2.32 2.55 1.79 -2.30 -3.46 8.31 9.00 9.53 6.46 2.73 8.92 9.62 9.42 3.19 -1.34
Cytoplasm -4.89 3.74 -5.66 -1.26 -13.47 0.83 1.56 -6.54 -7.80 -5.81 -2.80 7.67 -8.17 -6.27 -16.53
Cytoplasmic Foci -15.06 -2.00 3.84 30.51 7.92 -5.20 15.24 11.22 16.83 -8.19 -13.18 9.42 14.10 32.14 1.31
Eisosomes -1.23 3.67 2.99 6.18 -3.18 5.55 6.24 6.38 9.65 4.08 5.66 6.44 6.43 11.40 -0.62
Endoplasmic Reticulum -0.24 -0.92 1.08 2.40 3.21 0.56 -1.81 3.29 3.08 4.45 1.04 -0.26 3.76 3.71 4.61
Endosome 7.77 5.23 9.19 3.14 7.13 -18.54 -8.67 -18.19 0.39 1.29 -9.28 -10.99 -7.60 2.08 5.78
Golgi -2.37 -6.34 0.06 4.57 8.99 14.96 29.98 25.27 13.34 -10.89 15.81 14.33 23.05 13.19 7.34
Lipid Particles -7.52 0.96 1.06 9.36 0.06 5.72 8.99 13.03 10.40 3.96 3.64 11.63 12.86 13.79 2.45
Mitochondria -0.57 2.35 2.12 10.76 -3.25 16.87* 23.94 23.20 12.58 -5.92 17.03 22.72 22.16 15.93 -6.11
Mitotic Spindle 0.27 -2.30 -0.67 -1.68 2.41 -4.31 -4.79 -9.00 -5.03 0.55 -3.85 -7.46 -7.74 -4.41 2.70
None -3.14 -0.99 -1.33 3.07 -0.37 1.35 1.20 1.52 1.27 1.45 0.48 1.44 1.51 3.28 0.98
Nuclear Periphery -1.76 -2.66 -1.43 1.16 2.31 -3.13 -5.15 -4.90 -2.08 4.67 -2.72 -4.67 -5.23 0.76 3.97
Nuclear Periphery Foci -3.72 -4.07 -3.12 -0.71 1.92 -1.61 -3.46 -2.66 -2.39 3.02 -5.25 -5.69 -4.48 -1.64 3.94
Nucleolus -4.80 -1.04 -0.75 4.65 0.79 0.61 -3.76 1.09 0.63 4.18 -3.56 -2.70 0.81 4.71 3.53
Nucleus -3.43 1.68 0.80 4.78 -1.76 1.39 -3.60 1.89 0.73 4.03 -0.37 -1.89 2.13 4.14 3.42
Peroxisomes 2.70 5.51 4.08 3.05 -3.11 8.15 0.28 2.24 -4.49 0.68 6.69 6.51 4.79 -1.49 -2.89
Vacuole 8.14 -2.28 -8.40 -28.88 -8.25 -22.00 -22.02 -39.89 -20.56 7.41 -8.81 -24.99 -37.86 -34.63 -1.12
Vacuole Periphery -0.67 -11.53 -5.48 -6.55 8.38 -8.25 0.01 -2.61 6.43 -1.32 -6.08 -11.52 -6.08 0.12 9.10
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Subunit of RAVE complex (Rav1p, Rav2p, Skp1p); the RAVE complex promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate
Localization
Cell Percentages mitochondrion (16%)
Cell Cycle Regulation No
Subcompartmental Group mito-1

Rav1

Rav1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rav1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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