Standard name
Human Ortholog
Description Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.14 0.13 0.22 0.13 0.12 0.15 0.06 0.06 0.09 0.07 0.09 0.09 0.09 0.1 0.06 0.13 0.15 0.1 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.95 0.96 0.94 0.86 0.92 0.84 0.79 0.75 0.68 0.74 0.99 0.98 1.0 0.91 0.91 0.92 0.96 0.95 0.94 0.84 0.86 0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.09 0.06
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.05 0.05 0.13 0.12 0.1 0.22 0.24 0.38 0.33 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.06 0 0.11 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 1 1 2 1 1 0 0 0 0 0 0 1 0 0 0 0 1 0
Bud 1 1 0 1 0 1 1 0 3 3 4 2 4 1 1 0 0 0 0 1 0 0 1 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 29 36 37 10 18 15 9 11 13 8 9 14 25 41 27 51 38 23 1 0 0 1 0 2
Cytoplasm 197 274 162 76 147 89 149 150 110 85 70 120 287 408 468 355 224 205 188 270 163 194 335 343
Endoplasmic Reticulum 0 4 0 0 0 1 2 0 3 2 1 3 3 11 1 12 10 7 2 2 1 25 33 22
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 3 0 0 1 0 1 0 1 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 2 0 0 1 0
Mitochondria 2 0 1 4 8 13 19 18 31 27 39 53 0 1 0 2 2 0 0 1 0 1 1 1
Nucleus 4 0 2 1 0 1 2 3 4 6 2 5 0 1 0 9 10 8 0 0 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 1 7 2 3 6 0 19 3 3 2 3 0 0 0 12 9 7 0 2 1 4 6 2
Unique Cell Count 201 279 171 79 156 103 162 179 140 114 103 163 291 418 469 389 247 223 197 283 175 231 390 381
Labelled Cell Count 233 316 209 94 176 126 183 202 169 136 128 200 319 466 497 444 294 251 197 283 175 231 390 381


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 10.3 12.5 9.4 8.1 8.9 7.8 7.4 8.6 6.8 6.3 6.3 6.7 10.1 11.4 12.1 13.7 13.9 12.7 9.2 9.4 10.4
Std Deviation (1e-4) 1.6 2.5 1.7 1.2 1.4 1.9 1.2 1.7 1.2 1.2 1.3 1.3 1.5 1.9 1.8 2.6 3.0 2.8 1.5 1.5 1.4
Intensity Change (Log2) -0.21 -0.07 -0.28 -0.35 -0.12 -0.47 -0.58 -0.58 -0.49 0.1 0.28 0.37 0.54 0.56 0.43 -0.03 0.01 0.14


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -1.7 -2.4 -1.4 -4.3 -4.2 -3.0 -3.3 -2.8 -3.3 -4.0 -3.8 -5.9 -2.6 -1.6 -3.1
Cytoplasm 0.5 -0.2 -2.4 -1.0 -3.3 -4.3 -4.9 -6.0 -5.3 2.4 1.8 4.6 -1.4 -1.5 -1.1
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.4 4.3 3.9 6.2 6.4 8.5 7.9 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 2.3 0 0 0 0 0 0 0 -0.6 -0.2 -0.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.422 9.6902 8.3505 7.8996 6.5466 8.5972 8.0651 10.5827 8.8661 6.9507 7.9736 9.294 7.0301 8.2682 6.9258 8.4368 5.6769 7.6133
Actin 0.0306 0.0007 0.0145 0.0026 0.0188 0.0086 0.0322 0.0019 0.0168 0.0709 0.0044 0.0028 0.0015 0.0021 0.0157 0.004 0.0267 0.0012
Bud 0.0007 0.0001 0.0033 0.0009 0.0008 0.0005 0.0013 0.0037 0.0008 0.0035 0.0006 0.0003 0.0001 0.0002 0.0005 0.0004 0.0011 0.0001
Bud Neck 0.0023 0.0004 0.0046 0.0021 0.0014 0.0033 0.0038 0.0004 0.0012 0.0016 0.002 0.0027 0.0003 0.0009 0.0015 0.0011 0.0016 0.002
Bud Periphery 0.0013 0.0001 0.0044 0.0021 0.0016 0.001 0.0018 0.0014 0.001 0.0052 0.0009 0.0009 0.0002 0.0002 0.0008 0.0004 0.0013 0.0002
Bud Site 0.0115 0.0021 0.008 0.0026 0.0024 0.0013 0.0085 0.0173 0.0016 0.0032 0.0007 0.0002 0.0006 0.004 0.0051 0.0006 0.0014 0.0001
Cell Periphery 0.0067 0.0043 0.0085 0.0044 0.0059 0.0031 0.0044 0.0029 0.0032 0.0016 0.002 0.0018 0.004 0.0023 0.0029 0.0015 0.0008 0.0013
Cytoplasm 0.7617 0.9802 0.9078 0.8776 0.7708 0.8383 0.7976 0.962 0.9008 0.619 0.8839 0.9421 0.9449 0.9496 0.9094 0.9277 0.8668 0.9759
Cytoplasmic Foci 0.0246 0.0008 0.0075 0.0046 0.0325 0.0065 0.0249 0.0023 0.0048 0.0183 0.0107 0.0046 0.0032 0.0035 0.0081 0.0075 0.0108 0.0023
Eisosomes 0.0006 0 0.0001 0.0001 0.0002 0.0003 0.0003 0 0.0001 0.0002 0.0001 0 0 0 0.0005 0 0.0002 0
Endoplasmic Reticulum 0.0366 0.008 0.0089 0.0065 0.0066 0.0231 0.0188 0.0027 0.0081 0.0064 0.0435 0.0128 0.0235 0.0249 0.0128 0.0036 0.0142 0.0102
Endosome 0.0239 0.0003 0.0063 0.0164 0.0337 0.0162 0.0297 0.0008 0.0203 0.0857 0.0273 0.0098 0.0057 0.0026 0.0108 0.0126 0.031 0.0028
Golgi 0.0117 0.0002 0.0046 0.0081 0.0426 0.0104 0.0217 0.0003 0.0092 0.0197 0.0123 0.0043 0.0018 0.0009 0.0046 0.0022 0.0138 0.0008
Lipid Particles 0.0191 0.0001 0.0054 0.0056 0.0196 0.0035 0.0103 0.0003 0.0041 0.0035 0.0011 0.0035 0.001 0.0009 0.0035 0.0022 0.0029 0.0003
Mitochondria 0.0087 0 0.0012 0.0539 0.0204 0.0424 0.0134 0.0001 0.0147 0.0727 0.0042 0.0049 0.0073 0.0002 0.0108 0.0003 0.0047 0.0002
None 0.0127 0.0011 0.0015 0.0007 0.0204 0.0217 0.0091 0.0008 0.0007 0.0036 0.0009 0.0005 0.0017 0.0034 0.0031 0.002 0.0045 0.0006
Nuclear Periphery 0.0092 0.0002 0.0004 0.0005 0.0012 0.0112 0.0017 0.0002 0.0024 0.0065 0.0007 0.0008 0.0005 0.0003 0.0017 0.0079 0.004 0.0003
Nucleolus 0.0011 0 0.0001 0.0002 0.0002 0.0004 0.0003 0.0001 0.0003 0.0003 0 0 0 0 0.0001 0.0003 0.0001 0
Nucleus 0.0035 0.0002 0.0008 0.0007 0.0007 0.0021 0.0013 0.0006 0.001 0.0026 0.0005 0.0005 0.0003 0.0004 0.0009 0.0022 0.0015 0.0003
Peroxisomes 0.0115 0 0.0063 0.0008 0.0161 0.0008 0.0095 0 0.0009 0.0107 0.0002 0.0052 0.0002 0 0.0015 0.0005 0.0068 0
Punctate Nuclear 0.0088 0 0.0002 0.0001 0.0011 0.0015 0.0009 0.0002 0.0004 0.0061 0.0001 0.0004 0.0001 0.0001 0.0013 0.0196 0.0009 0
Vacuole 0.0117 0.0012 0.0054 0.0085 0.0024 0.0022 0.0072 0.0017 0.0058 0.0393 0.0032 0.0013 0.003 0.0032 0.0039 0.003 0.0038 0.0011
Vacuole Periphery 0.0014 0 0.0002 0.0012 0.0007 0.0017 0.0013 0.0001 0.0017 0.0194 0.0006 0.0005 0.0001 0.0001 0.0004 0.0002 0.001 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 17.0653 20.4742 21.1507 37.3003 26.4928 25.5837 33.4877 45.0669 41.0428 35.2405
Translational Efficiency 0.9114 0.9343 1.0371 0.7699 0.8533 0.9604 0.7544 0.7595 0.9352 0.7399

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1796 1273 100 244 1667 2104 157 683 3463 3377 257 927

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 950.30 1160.37 1459.76 1489.68 926.38 1046.57 1385.84 1349.13 938.79 1089.47 1414.60 1386.12
Standard Deviation 130.16 190.07 180.08 188.93 156.75 152.96 178.68 184.01 144.07 176.74 182.81 195.38
Intensity Change Log 2 0.288130 0.619276 0.648548 0.175993 0.581085 0.542353 0.233865 0.600550 0.597104

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001162 0.001057 0.005367 0.003761 0.000486 0.002321 0.002751 0.001709 0.000837 0.001844 0.003769 0.002249
Bud Neck 0.003761 0.001396 0.006346 0.004361 0.002370 0.005452 0.004964 0.002997 0.003091 0.003923 0.005502 0.003356
Bud Site 0.039561 0.035350 0.065024 0.062525 0.027737 0.047135 0.051671 0.039130 0.033869 0.042692 0.056867 0.045288
Cell Periphery 0.001547 0.000754 0.002495 0.004428 0.000572 0.000766 0.000961 0.001163 0.001078 0.000761 0.001558 0.002022
Cytoplasm 0.827011* 0.832317* 0.665775* 0.789906* 0.812668* 0.759962* 0.476688* 0.787804* 0.820107* 0.787237* 0.550262* 0.788357*
Cytoplasmic Foci 0.076373 0.080687 0.104513 0.032980 0.089980 0.118426 0.141305 0.043662 0.082923 0.104199 0.126989 0.040850
Eisosomes 0.000202 0.000034 0.000052 0.000055 0.000068 0.000164 0.000085 0.000032 0.000138 0.000115 0.000072 0.000038
Endoplasmic Reticulum 0.002783 0.003355 0.004137 0.000210 0.001921 0.001075 0.000727 0.000223 0.002368 0.001934 0.002054 0.000219
Endosome 0.004247 0.004490 0.006775 0.001278 0.006907 0.006334 0.012534 0.004558 0.005527 0.005639 0.010293 0.003695
Golgi 0.007597 0.006985 0.002550 0.000700 0.006397 0.012193 0.001302 0.004541 0.007019 0.010230 0.001788 0.003530
Lipid Particles 0.001300 0.001639 0.014031 0.011093 0.001276 0.001356 0.004963 0.005090 0.001288 0.001463 0.008492 0.006670
Mitochondria 0.001606 0.000500 0.000009 0.000003 0.001001 0.001954 0.000174 0.000118 0.001315 0.001406 0.000109 0.000088
Mitotic Spindle 0.000196 0.003439 0.001705 0.000124 0.000361 0.001833 0.002406 0.001107 0.000276 0.002438 0.002133 0.000848
None 0.001298 0.001073 0.000235 0.000212 0.001775 0.001215 0.000115 0.000189 0.001528 0.001161 0.000162 0.000195
Nuclear Periphery 0.000012 0.000048 0.000072 0.000020 0.000066 0.000015 0.000235 0.000063 0.000038 0.000028 0.000172 0.000051
Nuclear Periphery Foci 0.000531 0.001201 0.016800 0.005953 0.000717 0.000433 0.008195 0.002698 0.000620 0.000722 0.011543 0.003554
Nucleolus 0.000090 0.000209 0.000031 0.000037 0.000131 0.000187 0.002786 0.000096 0.000110 0.000195 0.001714 0.000080
Nucleus 0.004727 0.003463 0.009536 0.002723 0.006580 0.005828 0.005665 0.002990 0.005619 0.004936 0.007171 0.002920
Peroxisomes 0.000968 0.001068 0.000828 0.001101 0.000857 0.002045 0.005853 0.001408 0.000915 0.001677 0.003898 0.001327
Vacuole 0.023221 0.019213 0.092644 0.078400 0.036313 0.029428 0.276100* 0.098860 0.029523 0.025577 0.204717* 0.093475
Vacuole Periphery 0.001808 0.001724 0.001076 0.000132 0.001814 0.001880 0.000519 0.001564 0.001811 0.001821 0.000736 0.001187

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.26 -4.32 -4.20 -5.17 1.76 -3.35 -3.13 -5.40 1.27 1.46 -2.59 -4.93 -4.84 -0.70 2.73
Bud Neck 10.01 -3.71 -1.33 -7.78 2.86 -6.78 -4.50 -2.37 5.61 3.50 -2.77 -5.38 -1.04 2.01 4.89
Bud Site 2.08 -4.43 -5.78 -6.66 0.87 -9.27 -5.52 -4.13 3.46 3.11 -5.87 -6.63 -5.02 -0.70 3.59
Cell Periphery 7.13 -2.74 -4.57 -6.09 -2.52 -3.94 -2.08 -4.90 -2.78 -0.79 5.45 -2.48 -4.36 -6.43 -1.37
Cytoplasm -0.79 7.54 4.63 4.85 -5.08 8.29 16.63 5.33 -0.36 -13.52 7.31 17.09 7.47 2.80 -13.05
Cytoplasmic Foci -1.15 -3.81 10.33 10.22 7.97 -7.15 -5.42 12.34 19.81 10.55 -7.67 -6.88 15.27 21.38 12.93
Eisosomes 3.71 3.23 3.24 -2.41 0.08 -7.99 -1.17 5.10 13.24 6.35 0.92 2.78 4.24 11.48 5.64
Endoplasmic Reticulum -0.53 -0.37 5.20 3.31 1.89 1.65 2.67 3.72 3.93 4.43 0.85 0.83 6.36 4.50 2.29
Endosome -0.34 -1.56 7.18 5.10 3.71 0.80 -2.93 2.73 2.37 4.47 -0.22 -3.66 3.06 3.23 5.14
Golgi 0.76 11.33 17.55 8.92 6.25 -7.26 9.32 1.69 5.10 -1.62 -5.60 14.45 3.53 5.96 -1.12
Lipid Particles -1.89 -6.04 -7.15 -6.84 1.52 -0.64 -6.26 -7.53 -7.46 -0.20 -1.76 -7.62 -10.29 -9.91 1.96
Mitochondria 1.80 2.90 2.91 1.88 3.66 -1.32 1.72 1.86 3.45 0.30 -0.18 3.26 3.36 3.81 0.19
Mitotic Spindle -2.40 -2.62 0.69 2.44 2.73 -2.77 -1.31 -1.22 1.37 0.82 -3.56 -2.05 -1.33 2.54 1.40
None 1.12 6.69 6.50 5.24 0.44 2.20 6.97 6.69 9.17 -0.87 2.31 9.69 9.45 10.42 -0.33
Nuclear Periphery -1.59 -6.99 -6.33 1.14 5.99 1.59 -0.93 0.12 -1.33 0.96 0.56 -1.32 -0.43 -0.85 1.16
Nuclear Periphery Foci -2.74 -8.92 -9.17 -7.47 5.82 4.33 -7.11 -7.10 -8.21 4.97 -1.05 -11.00 -11.21 -10.33 7.80
Nucleolus -0.94 10.37 10.54 1.21 -1.00 -1.20 -0.96 3.43 1.99 0.98 -1.41 -0.95 4.41 1.80 0.98
Nucleus 4.18 -4.19 5.77 1.83 5.41 1.37 0.68 5.21 3.19 1.28 1.90 -1.99 5.53 3.12 3.85
Peroxisomes -0.63 0.84 -1.10 0.23 -1.74 -4.86 -1.28 -3.12 3.05 1.12 -4.22 -1.24 -3.49 2.31 1.05
Vacuole 2.77 -5.90 -9.76 -10.36 1.02 3.73 -12.52 -14.68 -16.31 7.77 3.40 -12.95 -18.14 -19.21 6.62
Vacuole Periphery 0.20 1.59 6.56 4.68 1.47 -0.15 5.49 0.72 0.72 -1.09 -0.03 4.28 1.49 1.38 -0.60
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Serine/threonine protein kinase; involved in regulation of ion transport across plasma membrane; carboxyl terminus is essential for glucose-dependent Pma1p activation via phosphorylation of Pma1p-Ser899; enhances spermine uptake; PTK2 has a paralog, PTK1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-4

Ptk2

Ptk2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ptk2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available