Standard name
Human Ortholog
Description Conserved nuclear protein that interacts with GTP-Gsp1p; stimulates nucleotide release from Gsp1p; involved in nuclear protein import; nucleotide release is inhibited by Yrb1p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.96 0.96 0.88 0.89 0.85 0.72 – 0.73 0.67 0.6 0.59 0.98 0.98 0.98 0.93 0.9 0.89 0.91 0.86 0.9 0.92 0.9 0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.2 0.09 – 0.29 0.26 0.34 0.36 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0.06 0.05 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0.09 0.16 0.14 0.08 0.29 – 0.13 0.14 0.19 0.12 0 0 0 0.17 0.16 0.17 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 1
Bud 0 1 1 1 0 5 2 – 1 2 1 12 0 0 0 0 0 0 1 10 5 3 8 8
Bud Neck 0 0 0 0 0 1 0 – 0 0 0 0 0 0 0 0 0 0 0 4 1 1 1 3
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 3 2 1 – 2 3 4 1 0 0 3 1 2 1 0 0 0 0 0 0
Cytoplasm 77 459 395 284 308 282 410 – 256 215 172 207 298 443 412 158 214 195 76 419 383 244 321 315
Endoplasmic Reticulum 1 4 1 0 1 0 0 – 1 3 0 1 1 0 1 10 5 9 0 0 3 2 1 1
Endosome 0 0 2 0 5 0 4 – 0 1 1 3 0 0 1 0 1 0 1 2 3 0 2 4
Golgi 0 1 0 0 0 0 1 – 0 0 0 0 2 1 0 0 2 0 0 4 0 0 2 1
Mitochondria 1 8 1 9 6 67 53 – 103 82 99 127 0 0 2 2 4 1 0 5 4 2 1 1
Nucleus 0 9 1 2 6 6 12 – 12 19 13 27 0 2 0 7 3 6 0 19 5 2 1 1
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 3 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 2 1 0 2 1 0 0 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 1 – 0 0 0 3 0 0 0 0 0 0 0 6 4 2 3 3
Vac/Vac Membrane 1 16 39 53 48 25 162 – 45 45 56 42 6 8 4 29 39 38 0 9 2 1 0 4
Unique Cell Count 80 477 412 323 348 331 568 352 320 288 353 304 453 419 170 237 218 84 489 425 266 355 351
Labelled Cell Count 80 498 440 350 377 388 646 420 370 348 427 307 456 424 207 270 250 84 489 425 266 355 351


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 5.8 6.6 6.4 6.9 4.8 6.1 – 5.4 5.6 5.7 5.3 7.0 7.3 7.0 10.4 11.0 10.6 5.6 6.0 6.2
Std Deviation (1e-4) 1.2 1.1 1.6 1.4 1.5 1.2 1.4 – 1.2 1.2 2.5 1.2 1.7 1.7 1.5 2.3 2.2 2.3 1.4 1.6 1.5
Intensity Change (Log2) – – – -0.04 0.07 -0.45 -0.12 – -0.29 -0.24 -0.21 -0.32 0.08 0.16 0.09 0.66 0.74 0.68 -0.23 -0.13 -0.1

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 3.4 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -4.0 -3.8 -5.1 -9.6 – -9.0 -10.3 -12.0 -12.5 1.6 1.6 2.1 -1.5 -2.8 -3.1
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 6.2 – 11.7 10.7 12.7 13.2 0 0 0 0 0 0
Nucleus 0 0 0 2.5 – 3.4 4.7 4.0 5.4 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole 2.8 1.9 -0.9 7.3 – 1.5 1.9 3.8 1.1 -4.1 -5.0 -5.5 2.6 2.6 2.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin 0.0233 0.0009 0.0043 0.0372 0.0037 0.0107 0.0196 0.0005 0.0156 0.0391 0.0192 0.0017 – – – – – –
Bud 0.0005 0.0013 0.0003 0.0018 0.001 0.0004 0.0009 0.0002 0.002 0.0006 0.0028 0.0003 – – – – – –
Bud Neck 0.0064 0.0004 0.0007 0.0009 0.0011 0.0137 0.0009 0.0039 0.005 0.0015 0.0158 0.0012 – – – – – –
Bud Periphery 0.0005 0.0002 0.0002 0.0023 0.0011 0.0006 0.0007 0 0.0013 0.0008 0.0031 0.0001 – – – – – –
Bud Site 0.0062 0.0021 0.001 0.0022 0.0009 0.0003 0.0026 0.0021 0.0041 0.0019 0.0506 0.0002 – – – – – –
Cell Periphery 0.0003 0.0001 0.0001 0.0001 0 0.0001 0.0001 0 0.0003 0.0001 0.0005 0 – – – – – –
Cytoplasm 0.6402 0.8453 0.8597 0.7045 0.779 0.8295 0.7618 0.9073 0.7825 0.8226 0.8037 0.87 – – – – – –
Cytoplasmic Foci 0.0319 0.0095 0.0069 0.0202 0.0177 0.0169 0.0136 0.0067 0.0126 0.017 0.0084 0.0105 – – – – – –
Eisosomes 0.0003 0 0 0.0002 0 0 0.0001 0 0.0003 0.0002 0.0001 0 – – – – – –
Endoplasmic Reticulum 0.0078 0.0053 0.0045 0.0031 0.0034 0.0046 0.0049 0.0019 0.0031 0.0086 0.0061 0.0045 – – – – – –
Endosome 0.034 0.0049 0.0066 0.0191 0.018 0.0123 0.0132 0.0014 0.0126 0.0102 0.0125 0.0052 – – – – – –
Golgi 0.015 0.0008 0.0023 0.0075 0.0042 0.0015 0.0048 0.0003 0.0053 0.0059 0.0018 0.001 – – – – – –
Lipid Particles 0.0255 0.0011 0.0013 0.0211 0.0011 0.0027 0.0051 0.0001 0.0031 0.0044 0.0008 0.0002 – – – – – –
Mitochondria 0.0157 0.0006 0.0019 0.0044 0.0116 0.0011 0.0041 0.0002 0.0108 0.0022 0.0013 0.0015 – – – – – –
None 0.0861 0.0616 0.0448 0.0883 0.0607 0.0247 0.0673 0.0268 0.0356 0.0301 0.0176 0.0169 – – – – – –
Nuclear Periphery 0.0146 0.0061 0.0055 0.0053 0.0154 0.0089 0.0145 0.0027 0.0059 0.0097 0.0203 0.0088 – – – – – –
Nucleolus 0.0071 0.0004 0.0001 0.0012 0.0007 0.0003 0.0005 0.0001 0.0015 0.0002 0.0005 0.0005 – – – – – –
Nucleus 0.051 0.0425 0.052 0.0327 0.0404 0.0577 0.0688 0.043 0.086 0.0307 0.0253 0.0646 – – – – – –
Peroxisomes 0.0111 0.0089 0.0035 0.0262 0.0168 0.0016 0.0072 0.0007 0.0048 0.0079 0.0011 0.0024 – – – – – –
Punctate Nuclear 0.0183 0.0064 0.0028 0.02 0.0197 0.01 0.0063 0.0016 0.0061 0.0046 0.0059 0.0095 – – – – – –
Vacuole 0.0029 0.0013 0.0011 0.0014 0.0027 0.002 0.0021 0.0007 0.0011 0.001 0.002 0.0007 – – – – – –
Vacuole Periphery 0.0013 0.0003 0.0003 0.0005 0.0007 0.0005 0.0009 0.0001 0.0005 0.0007 0.0008 0.0003 – – – – – –

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 57.9413 63.056 49.0184 47.3023 45.7273 58.7485 57.3044 53.2764 59.8981 52.6802
Translational Efficiency 1.6018 1.1525 1.5324 1.4773 1.8815 1.744 1.3133 1.4682 1.4928 1.5431

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
97 1250 584 1980 1470 1991 2128 1738 1567 3241 2712 3718

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 706.62 841.95 1025.09 924.62 711.30 856.31 985.54 1019.68 711.01 850.77 994.06 969.06
Standard Deviation 97.16 128.45 146.19 154.30 102.93 115.52 145.23 151.61 102.59 120.88 146.34 160.23
Intensity Change Log 2 — 0.252800 0.536744 0.387926 — 0.267675 0.470456 0.519586 — 0.260281 0.503871 0.455475

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000482 0.000332 0.000519 0.000294 0.000110 0.000101 0.000329 0.000752 0.000133 0.000190 0.000370 0.000508
Bud Neck 0.026697 0.011771 0.003079 0.003487 0.005191 0.014274 0.003356 0.007899 0.006522 0.013309 0.003296 0.005550
Bud Site 0.062237 0.011184 0.004901 0.017828 0.003483 0.013485 0.003827 0.022054 0.007120 0.012598 0.004058 0.019804
Cell Periphery 0.000338 0.000117 0.000123 0.000113 0.000131 0.000078 0.000084 0.000110 0.000144 0.000093 0.000092 0.000112
Cytoplasm 0.338449 0.622021 0.284834 0.689635 0.580525 0.649790 0.522303 0.581890 0.565540 0.639080 0.471167 0.639269
Cytoplasmic Foci 0.252077 0.105302 0.003101 0.010702 0.120333 0.062094 0.003082 0.018368 0.128488 0.078759 0.003086 0.014286
Eisosomes 0.000198 0.000043 0.000028 0.000017 0.000058 0.000028 0.000012 0.000029 0.000067 0.000034 0.000016 0.000023
Endoplasmic Reticulum 0.002989 0.001625 0.005229 0.000877 0.000840 0.000360 0.001779 0.001215 0.000973 0.000848 0.002522 0.001035
Endosome 0.012552 0.008950 0.001181 0.003118 0.004478 0.004465 0.000765 0.006943 0.004978 0.006195 0.000854 0.004906
Golgi 0.001592 0.002061 0.000098 0.001949 0.001080 0.000979 0.000086 0.001809 0.001111 0.001397 0.000088 0.001884
Lipid Particles 0.008826 0.002676 0.000793 0.000470 0.003373 0.000917 0.000430 0.000733 0.003710 0.001596 0.000508 0.000593
Mitochondria 0.004979 0.003058 0.000639 0.000907 0.002403 0.002319 0.000604 0.002191 0.002562 0.002604 0.000611 0.001507
Mitotic Spindle 0.003488 0.008663 0.004114 0.028931 0.000652 0.011959 0.008812 0.027296 0.000827 0.010688 0.007800 0.028167
None 0.002434 0.006080 0.006431 0.011731 0.007498 0.004984 0.009474 0.007954 0.007185 0.005407 0.008819 0.009965
Nuclear Periphery 0.000387 0.000371 0.001444 0.000611 0.000413 0.000362 0.001148 0.000896 0.000411 0.000365 0.001212 0.000744
Nuclear Periphery Foci 0.000855 0.001143 0.001242 0.001360 0.000811 0.000156 0.001345 0.001058 0.000814 0.000537 0.001323 0.001219
Nucleolus 0.001312 0.001034 0.000300 0.000282 0.000955 0.000877 0.000212 0.000723 0.000977 0.000938 0.000231 0.000488
Nucleus 0.211278 0.150190 0.628577 0.145183 0.232048 0.182220 0.403857 0.193562 0.230762 0.169866 0.452248 0.167798
Peroxisomes 0.009601 0.003142 0.000268 0.000354 0.001833 0.002162 0.000320 0.000804 0.002314 0.002540 0.000309 0.000565
Vacuole 0.057364 0.058837 0.052978 0.080143 0.033184 0.047681 0.038088 0.121140 0.034681 0.051984 0.041294 0.099308
Vacuole Periphery 0.001866 0.001400 0.000121 0.002005 0.000603 0.000708 0.000088 0.002573 0.000681 0.000975 0.000095 0.002271

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.93 0.16 1.05 1.26 3.99 0.29 -5.61 -1.98 -2.06 -0.17 -1.11 -5.34 -2.42 -2.05 1.38
Bud Neck 2.00 3.15 3.23 5.11 1.33 -6.46 1.57 0.27 6.69 -1.30 -5.62 2.98 2.71 8.75 -0.55
Bud Site 2.99 3.33 2.99 0.09 -3.19 -6.06 -0.15 -4.37 1.81 -4.65 -3.33 2.19 -2.20 1.56 -6.64
Cell Periphery 5.82 4.91 6.57 3.23 5.66 4.19 3.47 4.05 -0.68 1.66 4.22 3.56 4.85 1.19 3.51
Cytoplasm -11.91 4.50 -8.98 7.18 -29.25 -7.50 19.06 14.14 22.47 -3.88 -8.60 23.08 8.26 20.52 -18.30
Cytoplasmic Foci 6.58 11.35 11.11 23.10 -8.92 12.54 30.15 28.15 20.12 -8.96 10.91 31.57 30.00 30.36 -13.34
Eisosomes 6.80 6.85 7.65 7.45 5.69 11.29 16.10 10.35 -2.62 -10.36 11.05 14.94 13.94 4.00 -3.40
Endoplasmic Reticulum 1.65 -4.44 2.33 1.98 10.02 5.99 -12.17 -7.66 -15.42 5.88 0.80 -14.16 -4.98 -5.93 12.31
Endosome 1.24 4.05 4.05 8.49 0.10 0.39 8.86 3.45 3.16 -4.06 -1.71 9.38 6.11 8.69 -4.43
Golgi -0.82 3.87 1.87 2.79 -2.04 0.29 3.07 1.36 1.53 -1.96 -0.75 3.33 1.37 2.93 -2.86
Lipid Particles 3.07 4.00 4.27 3.02 4.72 7.15 7.93 7.36 0.32 -4.72 5.06 8.54 8.58 3.12 0.22
Mitochondria 1.08 2.50 2.51 3.77 0.15 0.08 2.17 1.64 2.95 -1.24 -0.05 2.50 2.26 5.07 -1.14
Mitotic Spindle -2.29 -0.38 -6.73 -4.39 -7.14 -5.90 -6.20 -9.15 -3.29 -5.22 -7.25 -6.52 -13.32 -5.13 -7.69
None -3.20 -3.40 -7.55 -2.73 -5.33 2.50 -0.64 -0.69 -4.91 -0.20 1.89 -0.29 -1.49 -5.51 -2.54
Nuclear Periphery -0.15 -16.66 -14.96 -20.50 7.87 0.86 -22.70 -19.22 -18.80 -1.06 0.82 -27.06 -24.83 -26.00 4.35
Nuclear Periphery Foci -1.92 -4.69 -2.53 -0.74 3.04 5.49 -5.16 -2.64 -12.84 3.38 2.10 -6.11 -3.40 -8.66 3.88
Nucleolus 0.78 3.73 3.64 5.61 -0.66 0.27 5.75 3.07 2.85 -2.24 0.07 6.15 4.63 5.74 -2.72
Nucleus 2.79 -17.82 -0.57 -10.73 35.36 6.75 -29.97 -6.84 -14.27 23.36 9.40 -36.79 -3.39 -16.48 40.24
Peroxisomes 3.00 4.31 4.33 6.98 0.57 -0.61 3.73 3.49 6.86 -1.21 -0.38 4.89 4.81 9.87 -0.71
Vacuole -0.78 -3.90 -11.39 -17.59 -8.47 -5.57 -13.08 -27.95 -24.52 -17.79 -7.94 -14.87 -35.51 -30.32 -20.22
Vacuole Periphery 0.79 3.03 1.83 2.07 -2.53 -0.59 3.89 -0.55 -0.21 -2.74 -1.70 4.49 -0.29 1.11 -3.82
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Conserved nuclear protein that interacts with GTP-Gsp1p; stimulates nucleotide release from Gsp1p; involved in nuclear protein import; nucleotide release is inhibited by Yrb1p
Localization
Cell Percentages cytoplasm (70%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Mog1

Mog1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mog1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available