| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Component of the septin ring that is required for cytokinesis; present at the ends of rod-like septin hetero-oligomers; C-terminal extension is important for recruitment of Bni5p to the mother-bud neck, which in turn is required for Myo1p recruitment and cytokinesis; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells |
Micrographs
Sub-cellular Localization
Yeast GFP Assignment
Protein Abundance
Localization Change
External localization resources
| ensLOC | DeepLoc | |||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Localization | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | WT1 | WT2 | WT3 | AF100 | AF140 | AF180 |
| Cortical Patches | 30 | 25 | 24 | 15 | 7 | 20 | 25 | 17 | 22 | 26 | 21 | 14 | 39 | 44 | 33 | 40 | 27 | 22 | 22 | 23 | 20 | 69 | 109 | 99 |
| Bud | 13 | 9 | 13 | 13 | 18 | 31 | 25 | 23 | 31 | 32 | 30 | 26 | 14 | 20 | 11 | 18 | 16 | 7 | 90 | 60 | 71 | 133 | 156 | 163 |
| Bud Neck | 52 | 33 | 42 | 28 | 50 | 34 | 42 | 35 | 37 | 35 | 44 | 38 | 100 | 141 | 136 | 64 | 67 | 28 | 111 | 71 | 96 | 121 | 110 | 121 |
| Bud Site | 51 | 29 | 41 | 48 | 26 | 34 | 31 | 32 | 23 | 17 | 20 | 22 | 53 | 24 | 39 | 25 | 32 | 23 | – | – | – | – | – | – |
| Cell Periphery | 5 | 3 | 6 | 2 | 0 | 2 | 4 | 7 | 9 | 4 | 4 | 4 | 4 | 11 | 7 | 4 | 2 | 1 | 0 | 0 | 0 | 3 | 3 | 6 |
| Cytoplasm | 11 | 8 | 12 | 4 | 10 | 10 | 15 | 19 | 11 | 8 | 18 | 11 | 22 | 36 | 37 | 26 | 31 | 24 | 4 | 0 | 1 | 4 | 7 | 5 |
| Endoplasmic Reticulum | 2 | 2 | 1 | 1 | 1 | 5 | 2 | 1 | 3 | 4 | 3 | 5 | 3 | 1 | 2 | 5 | 6 | 1 | 0 | 1 | 2 | 0 | 2 | 2 |
| Endosome | 9 | 2 | 3 | 1 | 1 | 3 | 5 | 4 | 7 | 3 | 5 | 2 | 8 | 13 | 14 | 10 | 9 | 10 | 1 | 2 | 1 | 6 | 5 | 7 |
| Golgi | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 5 | 4 | 1 | 12 | 11 | 1 | 0 | 0 | 2 | 0 | 2 | 1 |
| Mitochondria | 12 | 5 | 11 | 11 | 9 | 21 | 42 | 28 | 38 | 40 | 38 | 48 | 1 | 1 | 2 | 28 | 21 | 23 | 2 | 2 | 1 | 7 | 9 | 10 |
| Nucleus | 8 | 6 | 9 | 5 | 9 | 4 | 4 | 9 | 3 | 7 | 5 | 14 | 10 | 12 | 13 | 8 | 1 | 1 | 3 | 3 | 0 | 0 | 0 | 0 |
| Nuclear Periphery | 1 | 0 | 0 | 2 | 0 | 2 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 3 | 6 | 4 |
| Nucleolus | 53 | 36 | 28 | 22 | 49 | 35 | 47 | 64 | 45 | 47 | 55 | 65 | 45 | 45 | 64 | 89 | 84 | 61 | 4 | 12 | 5 | 2 | 1 | 1 |
| Peroxisomes | 19 | 4 | 12 | 9 | 6 | 16 | 18 | 24 | 16 | 13 | 11 | 5 | 34 | 30 | 38 | 15 | 12 | 14 | 3 | 0 | 2 | 2 | 5 | 8 |
| SpindlePole | 12 | 2 | 18 | 12 | 10 | 4 | 7 | 9 | 11 | 11 | 12 | 13 | 51 | 106 | 68 | 35 | 26 | 24 | 5 | 3 | 10 | 2 | 1 | 5 |
| Vac/Vac Membrane | 3 | 3 | 3 | 0 | 2 | 0 | 1 | 5 | 0 | 1 | 0 | 3 | 7 | 12 | 11 | 14 | 3 | 6 | 3 | 3 | 0 | 2 | 1 | 1 |
| Unique Cell Count | 193 | 131 | 167 | 117 | 136 | 146 | 179 | 198 | 170 | 171 | 190 | 187 | 327 | 396 | 386 | 291 | 248 | 187 | 256 | 193 | 222 | 365 | 428 | 443 |
| Labelled Cell Count | 281 | 167 | 224 | 173 | 199 | 221 | 268 | 279 | 257 | 250 | 266 | 271 | 396 | 500 | 476 | 393 | 348 | 246 | 256 | 193 | 222 | 365 | 428 | 443 |
Yeast GFP Assignment
Protein Abundance
| Screen | WT1 | WT2 | WT3 | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 | AF100 | AF140 | AF180 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean Cell GFP Intensity (1e-4) | 11.5 | 15.3 | 11.7 | 10.2 | 9.9 | 10.2 | 10.0 | 9.6 | 9.3 | 9.1 | 8.7 | 8.7 | 14.4 | 13.7 | 12.9 | 18.9 | 17.5 | 17.8 | 13.7 | 14.2 | 14.4 |
| Std Deviation (1e-4) | 3.5 | 4.3 | 3.7 | 2.8 | 3.5 | 4.6 | 3.9 | 3.7 | 2.9 | 2.8 | 3.2 | 2.9 | 3.5 | 3.7 | 4.1 | 6.9 | 6.6 | 7.1 | 3.1 | 2.8 | 2.8 |
| Intensity Change (Log2) | – | – | – | -0.19 | -0.23 | -0.19 | -0.23 | -0.28 | -0.33 | -0.36 | -0.43 | -0.43 | 0.3 | 0.23 | 0.15 | 0.69 | 0.58 | 0.61 | 0.23 | 0.28 | 0.3 |
Localization Change
| Localization | RAP60 | RAP140 | RAP220 | RAP300 | RAP380 | RAP460 | RAP540 | RAP620 | RAP700 | HU80 | HU120 | HU160 | rpd3Δ_1 | rpd3Δ_2 | rpd3Δ_3 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cortical Patches | -0.4 | -2.6 | -0.2 | -0.1 | -1.7 | -0.4 | 0.2 | -0.9 | -2.1 | -0.8 | -1.1 | -2.1 | -0.2 | -1.1 | -0.7 |
| Bud | 1.0 | 1.6 | 3.4 | 1.8 | 1.2 | 2.8 | 3.0 | 2.3 | 1.8 | -1.6 | -1.3 | -2.6 | -0.7 | -0.5 | -1.6 |
| Bud Neck | -0.2 | 2.2 | -0.4 | -0.4 | -1.7 | -0.7 | -1.0 | -0.4 | -1.1 | 1.3 | 2.4 | 2.3 | -0.8 | 0.4 | -2.4 |
| Bud Site | 2.9 | -1.1 | -0.3 | -1.7 | -2.0 | -2.6 | -3.6 | -3.5 | -3.1 | -2.2 | -6.3 | -4.4 | -4.7 | -3.1 | -3.0 |
| Cell Periphery | 0 | 0 | 0 | 0 | 0 | 0.8 | 0 | 0 | 0 | 0 | -0.5 | 0 | 0 | 0 | 0 |
| Cytoplasm | -1.4 | 0.1 | -0.1 | 0.4 | 0.8 | -0.3 | -1.0 | 0.8 | -0.5 | -0.2 | 0.7 | 0.9 | 0.7 | 1.7 | 1.8 |
| Endoplasmic Reticulum | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Endosome | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.1 | 0 | 0 | 1.8 |
| Golgi | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Mitochondria | 0.9 | 0 | 2.3 | 4.4 | 2.3 | 4.1 | 4.3 | 3.7 | 4.8 | 0 | 0 | 0 | 1.1 | 0.7 | 1.8 |
| Nucleus | -0.4 | 0.4 | -1.2 | -1.5 | -0.4 | -1.8 | -0.6 | -1.3 | 0.8 | -1.3 | -1.3 | -1.1 | -1.4 | 0 | 0 |
| Nuclear Periphery | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nucleolus | 0.4 | 3.8 | 1.6 | 2.1 | 3.4 | 2.2 | 2.4 | 2.7 | 3.8 | -0.9 | -1.7 | -0.1 | 3.3 | 3.8 | 3.4 |
| Peroxisomes | 0.2 | -1.0 | 1.2 | 0.9 | 1.6 | 0.7 | 0.1 | -0.5 | -2.0 | 1.2 | 0.2 | 1.0 | -0.9 | -1.0 | 0.1 |
| SpindlePole | -0.1 | -1.0 | -2.8 | -2.5 | -2.3 | -1.4 | -1.4 | -1.5 | -1.3 | 1.5 | 4.2 | 2.0 | 0.4 | -0.1 | 0.6 |
| Vacuole | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.6 | 0 | 0 |
External localization resources
Images
Protein Concentration and Protein Localization Data
| R1 | R2 | R3 | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Pre-START | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Concentration | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Actin | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Neck | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Bud Site | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cell Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasm | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Cytoplasmic Foci | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Eisosomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endoplasmic Reticulum | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Endosome | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Golgi | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Lipid Particles | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Mitochondria | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| None | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nuclear Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleolus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Nucleus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Peroxisomes | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Punctate Nuclear | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
| Vacuole Periphery | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Sequencing Data
| R1 | R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | G1 Post-START | S/G2 | Metaphase | Anaphase | Telophase | |
| Gene Expression | 70.289 | 81.4076 | 63.3404 | 64.4591 | 72.7916 | 83.9466 | 92.5002 | 98.9733 | 78.4099 | 76.4304 |
| Translational Efficiency | 1.4579 | 1.4716 | 1.1545 | 1.2163 | 1.2321 | 1.0873 | 1.1978 | 0.8887 | 0.9337 | 1.1049 |
Hit Data
| Dataset | Hit |
|---|---|
| Protein Concentration | – |
| Protein Localization | – |
| Gene Expression | ✘ |
| Translational Efficiency | ✘ |
Micrographs
Cell Count
| R1 | R2 | R1 & R2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 |
| 260 | 275 | 1997 | 1168 | 1375 | 1332 | 374 | 1073 | 1635 | 1607 | 2371 | 2241 |
Protein Abundance
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Mean | 1110.15 | 1332.97 | 1396.84 | 1604.40 | 1173.60 | 1199.61 | 1611.72 | 1644.26 | 1163.51 | 1222.43 | 1430.74 | 1623.49 |
| Standard Deviation | 197.07 | 271.88 | 299.57 | 346.08 | 216.48 | 229.52 | 306.29 | 331.66 | 214.77 | 242.56 | 310.68 | 339.84 |
| Intensity Change Log 2 | — | 0.263890 | 0.331412 | 0.531279 | — | 0.031625 | 0.457660 | 0.486498 | — | 0.149203 | 0.397668 | 0.508440 |
Localization Score (DeepLoc)
| R1 | R2 | R1 & R2 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | WT | UBP2 | UBP14 | UBP2UBP14 | |
| Actin | 0.015665 | 0.010682 | 0.002772 | 0.011909 | 0.020743 | 0.005840 | 0.010736 | 0.022902 | 0.019936 | 0.006669 | 0.004028 | 0.017172 |
| Bud Neck | 0.238026* | 0.207035* | 0.312230* | 0.205078* | 0.251444* | 0.271109* | 0.251557* | 0.193759* | 0.249310* | 0.260144* | 0.302660* | 0.199659* |
| Bud Site | 0.587341* | 0.599927* | 0.553985* | 0.659131* | 0.534196* | 0.578364* | 0.535059* | 0.682039* | 0.542647* | 0.582054* | 0.551000* | 0.670099* |
| Cell Periphery | 0.005959 | 0.004516 | 0.010545 | 0.005123 | 0.016740 | 0.012206 | 0.005273 | 0.005561 | 0.015025 | 0.010890 | 0.009713 | 0.005333 |
| Cytoplasm | 0.023975 | 0.030054 | 0.020892 | 0.019604 | 0.018486 | 0.023405 | 0.019362 | 0.027230 | 0.019359 | 0.024543 | 0.020651 | 0.023255 |
| Cytoplasmic Foci | 0.033006 | 0.068162 | 0.042500 | 0.041109 | 0.063890 | 0.039951 | 0.097671 | 0.025096 | 0.058979 | 0.044778 | 0.051202 | 0.033442 |
| Eisosomes | 0.004150 | 0.005034 | 0.007178 | 0.004177 | 0.017341 | 0.010355 | 0.007537 | 0.003118 | 0.015244 | 0.009445 | 0.007235 | 0.003670 |
| Endoplasmic Reticulum | 0.001737 | 0.000355 | 0.000479 | 0.000177 | 0.001006 | 0.000646 | 0.000727 | 0.000281 | 0.001122 | 0.000596 | 0.000518 | 0.000227 |
| Endosome | 0.004833 | 0.005183 | 0.001602 | 0.001310 | 0.002637 | 0.003604 | 0.001473 | 0.002568 | 0.002986 | 0.003874 | 0.001582 | 0.001912 |
| Golgi | 0.001857 | 0.002556 | 0.000692 | 0.002124 | 0.001264 | 0.001456 | 0.000817 | 0.001824 | 0.001358 | 0.001644 | 0.000711 | 0.001980 |
| Lipid Particles | 0.000378 | 0.000352 | 0.000198 | 0.000144 | 0.000648 | 0.000496 | 0.000278 | 0.000745 | 0.000605 | 0.000471 | 0.000211 | 0.000432 |
| Mitochondria | 0.029325 | 0.009471 | 0.007857 | 0.011914 | 0.017635 | 0.013152 | 0.003792 | 0.005183 | 0.019494 | 0.012522 | 0.007216 | 0.008691 |
| Mitotic Spindle | 0.002381 | 0.002702 | 0.002704 | 0.003473 | 0.001375 | 0.004359 | 0.002396 | 0.003454 | 0.001535 | 0.004076 | 0.002656 | 0.003464 |
| None | 0.000545 | 0.000391 | 0.000456 | 0.000333 | 0.000743 | 0.001422 | 0.000222 | 0.000244 | 0.000712 | 0.001245 | 0.000419 | 0.000290 |
| Nuclear Periphery | 0.000064 | 0.000044 | 0.000140 | 0.000098 | 0.000041 | 0.000055 | 0.000084 | 0.000110 | 0.000045 | 0.000053 | 0.000131 | 0.000104 |
| Nuclear Periphery Foci | 0.000668 | 0.000740 | 0.000973 | 0.000463 | 0.001492 | 0.001016 | 0.000943 | 0.000416 | 0.001361 | 0.000969 | 0.000968 | 0.000440 |
| Nucleolus | 0.002886 | 0.006302 | 0.003530 | 0.005173 | 0.005673 | 0.002207 | 0.013665 | 0.001819 | 0.005230 | 0.002908 | 0.005129 | 0.003567 |
| Nucleus | 0.004894 | 0.003137 | 0.003018 | 0.003176 | 0.003007 | 0.002782 | 0.006031 | 0.002358 | 0.003307 | 0.002842 | 0.003493 | 0.002784 |
| Peroxisomes | 0.021159 | 0.029460 | 0.012213 | 0.010553 | 0.028357 | 0.014519 | 0.019051 | 0.006833 | 0.027212 | 0.017076 | 0.013292 | 0.008772 |
| Vacuole | 0.018641 | 0.012557 | 0.015170 | 0.012902 | 0.012458 | 0.011963 | 0.022008 | 0.011902 | 0.013442 | 0.012064 | 0.016249 | 0.012423 |
| Vacuole Periphery | 0.002508 | 0.001340 | 0.000866 | 0.002029 | 0.000824 | 0.001092 | 0.001318 | 0.002558 | 0.001092 | 0.001135 | 0.000937 | 0.002282 |
Localization Changes (T-score)
| R1 | R2 | R1 & R2 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | UBP2_WT | UBP14_WT | UBP2UBP14_WT | UBP2UBP14_UBP2 | UBP2UBP14_UBP14 | |
| Actin | 0.77 | 2.33 | 0.65 | -0.31 | -4.60 | 5.97 | 2.60 | -0.45 | -5.03 | -2.66 | 5.66 | 7.08 | 1.05 | -5.02 | -6.67 |
| Bud Neck | 1.61 | -4.65 | 2.23 | 0.20 | 13.03 | -2.01 | 0.41 | 6.47 | 8.27 | 4.46 | -1.20 | -6.43 | 6.95 | 8.12 | 15.28 |
| Bud Site | -0.46 | 1.78 | -3.63 | -3.05 | -10.88 | -3.95 | 0.34 | -12.76 | -8.84 | -9.09 | -3.82 | -0.69 | -13.78 | -9.46 | -15.19 |
| Cell Periphery | 1.29 | -3.61 | 0.83 | -0.68 | 5.39 | 2.54 | 5.41 | 7.05 | 5.34 | -0.25 | 2.75 | 3.72 | 7.40 | 5.55 | 5.12 |
| Cytoplasm | -1.03 | 0.50 | 0.88 | 2.01 | 0.90 | -2.27 | -0.86 | -4.32 | -2.17 | -2.21 | -2.52 | -1.51 | -2.99 | -0.06 | -1.73 |
| Cytoplasmic Foci | -3.72 | -2.14 | -1.57 | 3.02 | 0.65 | 5.10 | -3.25 | 8.46 | 3.56 | 7.09 | 3.28 | 1.63 | 6.60 | 3.13 | 5.50 |
| Eisosomes | -0.83 | -3.20 | 0.02 | 1.12 | 4.66 | 4.26 | 6.29 | 10.24 | 7.66 | 5.00 | 4.18 | 6.48 | 9.81 | 7.27 | 6.85 |
| Endoplasmic Reticulum | 1.09 | 0.96 | 1.23 | 1.23 | 2.56 | 1.09 | -0.10 | 2.60 | 1.91 | 2.42 | 1.53 | 1.59 | 2.91 | 2.34 | 3.03 |
| Endosome | -0.18 | 3.36 | 3.70 | 2.54 | 0.74 | -1.44 | 2.40 | 0.09 | 1.22 | -1.42 | -1.40 | 3.26 | 2.28 | 3.06 | -0.69 |
| Golgi | -0.72 | 2.83 | -0.27 | 0.39 | -1.78 | -0.52 | 1.89 | -0.83 | -0.48 | -1.50 | -0.82 | 3.96 | -1.13 | -0.52 | -2.42 |
| Lipid Particles | 0.16 | 1.11 | 1.75 | 1.65 | 0.80 | 0.45 | 0.72 | -0.45 | -0.79 | -0.97 | 0.47 | 1.30 | 0.23 | -0.20 | -1.06 |
| Mitochondria | 2.53 | 2.99 | 2.37 | -0.68 | -2.24 | 1.60 | 5.91 | 5.26 | 4.05 | -1.17 | 2.61 | 5.39 | 4.54 | 2.06 | -1.28 |
| Mitotic Spindle | -0.39 | -0.83 | -1.34 | -0.61 | -0.79 | -3.39 | -2.28 | -2.62 | 0.66 | -0.84 | -3.40 | -3.55 | -3.55 | 0.59 | -1.08 |
| None | 1.39 | 0.98 | 2.23 | 0.82 | 2.81 | -0.89 | 6.58 | 6.28 | 1.53 | -0.57 | -0.84 | 4.28 | 6.49 | 1.50 | 3.40 |
| Nuclear Periphery | 1.26 | -0.93 | -1.55 | -2.64 | 0.44 | -1.63 | -3.46 | -1.71 | -1.36 | 0.21 | -1.12 | -1.37 | -2.75 | -2.31 | 0.42 |
| Nuclear Periphery Foci | -0.37 | -0.97 | 0.95 | 1.42 | 1.76 | 2.18 | 1.55 | 5.47 | 3.44 | 3.31 | 2.08 | 1.33 | 5.76 | 3.81 | 2.30 |
| Nucleolus | -1.15 | -0.47 | -1.59 | 0.42 | -1.73 | 2.91 | -2.30 | 3.18 | 0.69 | 3.52 | 2.07 | 0.07 | 1.56 | -0.83 | 1.95 |
| Nucleus | 0.67 | 0.75 | 0.62 | -0.20 | -0.43 | 0.37 | -2.22 | 0.37 | -0.01 | 2.28 | 0.71 | -1.48 | 0.08 | -0.75 | 1.73 |
| Peroxisomes | -1.16 | 2.30 | 2.70 | 3.06 | 1.29 | 5.27 | 3.03 | 8.97 | 4.64 | 4.91 | 4.03 | 6.61 | 8.91 | 4.92 | 4.32 |
| Vacuole | 1.60 | 0.82 | 1.59 | -0.35 | 1.83 | 0.40 | -3.61 | -0.54 | -0.80 | 3.27 | 1.16 | -3.05 | 0.12 | -1.06 | 3.19 |
| Vacuole Periphery | 1.25 | 1.85 | 0.47 | -1.20 | -2.32 | -0.81 | -1.64 | -2.26 | -1.81 | -1.40 | -0.11 | 0.63 | -2.50 | -2.29 | -2.92 |
| Standard name | |
|---|---|
| Human Ortholog | |
| Description | Component of the septin ring that is required for cytokinesis; present at the ends of rod-like septin hetero-oligomers; C-terminal extension is important for recruitment of Bni5p to the mother-bud neck, which in turn is required for Myo1p recruitment and cytokinesis; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells |
| Localization | |
| Cell Percentages | — |
| Cell Cycle Regulation | No |
| Subcompartmental Group | N/A |
Cdc11
Cdc11
Nearest neighbours ( genes)
correlation threshold
0.80
Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)
Endocytosis
| Temp | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Vph1-GFP) |
|---|---|---|---|---|
| 37℃ | ||||
| RT |
Cell Cycle Omics
CYCLoPs (Cdc11-GFP)
| Gene / Allele | Actin Patch (Sac6-tdTomato) | Cortical Patch (Sla1-GFP) | Late Endosome (Snf7-GFP) | Vacuole (Sac6-tdTomato) |
|---|
| Gene | Images |
|---|
| Gene | Images |
|---|
Images are not yet available
Images are not yet available
