Standard name
Human Ortholog
Description Large subunit of carbamoyl phosphate synthetase; carbamoyl phosphate synthetase catalyzes a step in the synthesis of citrulline, an arginine precursor

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0.37 0.17 0.11 0 0 0 0 0 0 0 0.08 0.08 0.07 0.07 0 0.44 0.5 0.38 0.21 0 0 0.1 0.12 0.08
Cytoplasm 0.68 0.89 0.95 1.0 1.0 0.99 0.95 0.96 0.96 0.92 0.9 0.9 0.96 0.96 0.98 0.64 0.63 0.7 0.74 0.95 0.95 0.85 0.82 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0.05 0.06 0.05 0 0 0 0 0 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 1 3 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 14 45 22 6 6 5 8 12 3 9 14 17 9 9 5 86 45 55 15 7 2 11 15 13
Cytoplasm 26 232 193 152 234 238 280 316 209 190 157 200 116 133 145 125 57 101 52 362 256 100 107 141
Endoplasmic Reticulum 0 0 0 0 0 2 12 4 6 11 10 12 0 0 0 2 4 7 0 2 2 0 2 1
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 0 0 0 1
Unique Cell Count 38 260 204 152 235 241 296 328 218 206 174 222 121 138 148 195 90 144 71 384 269 118 132 163
Labelled Cell Count 40 277 215 158 240 245 301 335 219 211 184 236 125 142 150 213 106 163 71 384 269 118 132 163


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 642.1 498.2 433.9 362.6 319.5 245.7 199.6 171.8 150.5 130.8 118.8 105.8 496.7 467.1 422.3 603.9 594.6 592.0 551.4 559.2 552.9
Std Deviation (1e-4) 60.8 90.0 83.2 74.9 64.8 64.3 52.6 45.6 42.0 45.1 43.0 42.3 84.6 90.0 77.0 127.1 149.8 138.4 160.5 159.0 124.2
Intensity Change (Log2) -0.26 -0.44 -0.82 -1.12 -1.34 -1.53 -1.73 -1.87 -2.04 0.19 0.11 -0.04 0.48 0.45 0.45 0.35 0.37 0.35

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000200400600WT3HU80HU120HU1600200400600WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30200400600WT1AF100AF140AF1800200400600
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.4 -3.5 -3.8 -3.7 -3.3 -4.1 -2.5 -0.9 -1.1 -1.0 -1.3 -2.6 7.5 7.4 6.1
Cytoplasm 2.9 3.2 2.5 0 1.0 0.6 -1.0 -1.6 -1.7 0.5 0.8 1.6 -7.6 -6.9 -6.2
Endoplasmic Reticulum 0 0 0 0 0 0 3.3 0 3.4 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 586.5545 871.3488 642.5129 760.4482 405.8297 238.906 433.8122 697.7408 580.1685 387.145 486.4264 586.7285 605.5671 828.3716 710.1399 541.9143 596.3872 630.6699
Actin 0.0231 0.0002 0.0027 0.0001 0.1055 0.0054 0.0041 0.0001 0.004 0.0003 0.0002 0.0002 0.001 0.0001 0.0002 0.0006 0.0001 0.0002
Bud 0.0016 0.0004 0.0007 0.0001 0.0009 0.0098 0.0015 0.0003 0.0008 0.0006 0.0002 0.0001 0.0007 0.0002 0.0003 0.0002 0.0003 0.0001
Bud Neck 0.0005 0.0001 0.0003 0.0002 0.0004 0.008 0.0004 0.0001 0.0004 0.0004 0.0006 0.0007 0.0002 0.0001 0.0003 0.0004 0.0002 0.0011
Bud Periphery 0.0008 0.0001 0.0002 0 0.0006 0.0082 0.0008 0 0.0004 0.0005 0.0001 0 0.0005 0 0.0001 0 0.0001 0
Bud Site 0.0015 0.0001 0.0006 0 0.0007 0.0039 0.0013 0.0001 0.001 0.0016 0.0001 0 0.0005 0.0001 0 0 0.0001 0
Cell Periphery 0.0006 0.0018 0.0007 0.0001 0.0009 0.0171 0.0038 0.0016 0.0009 0.0024 0.0013 0.0004 0.0007 0 0.0001 0.0006 0.0009 0.0001
Cytoplasm 0.7693 0.9782 0.8228 0.9858 0.5245 0.4726 0.7593 0.9848 0.9497 0.6246 0.7779 0.9515 0.9019 0.9916 0.989 0.9648 0.7345 0.8921
Cytoplasmic Foci 0.0334 0.0001 0.0454 0 0.0169 0.0421 0.0286 0.0001 0.0024 0.0414 0.0032 0.0003 0.0145 0 0.0001 0.0002 0.0626 0.0514
Eisosomes 0.001 0 0.0008 0 0.0024 0.0003 0.0014 0.0001 0.0001 0.0037 0.0002 0 0.0006 0 0 0 0.0019 0.0003
Endoplasmic Reticulum 0.0018 0 0.0022 0 0.0015 0.0212 0.002 0.0001 0.0007 0.0024 0.0002 0.0002 0.0002 0 0.0002 0.0001 0.0001 0.0001
Endosome 0.0102 0 0.0037 0 0.032 0.0143 0.0087 0 0.0013 0.0439 0.0001 0 0.0031 0 0 0 0.0001 0.0001
Golgi 0.0059 0 0.0009 0 0.0103 0.0016 0.0047 0 0.0006 0.0018 0 0 0.0005 0 0 0 0.0001 0
Lipid Particles 0.0135 0 0.006 0 0.0379 0.0031 0.0097 0.0001 0.0006 0.0121 0.0012 0.0001 0.002 0 0 0.0001 0.0055 0.0019
Mitochondria 0.0276 0.0009 0.0104 0.0002 0.0869 0.0563 0.0177 0.0004 0.0087 0.0408 0.0104 0.0003 0.0107 0.0003 0.0005 0.0002 0.0381 0.01
None 0.0151 0.0008 0.013 0.0002 0.0083 0.0539 0.0254 0.0009 0.0038 0.0376 0.0114 0.0007 0.0088 0.0002 0.0002 0.0004 0.0651 0.0025
Nuclear Periphery 0.0071 0.0014 0.0059 0.0027 0.0171 0.0308 0.0087 0.0019 0.0038 0.0067 0.0065 0.0076 0.0036 0.0005 0.0013 0.0054 0.0015 0.0037
Nucleolus 0.0278 0.001 0.0257 0 0.103 0.0227 0.0651 0.0006 0.0037 0.1098 0.1337 0.0013 0.0289 0 0 0.0001 0.0549 0.0154
Nucleus 0.0401 0.0132 0.0285 0.0103 0.0324 0.0642 0.0412 0.0076 0.0148 0.0267 0.0402 0.0352 0.0171 0.0067 0.0071 0.0261 0.0258 0.018
Peroxisomes 0.0133 0 0.0228 0 0.0037 0.0033 0.0034 0 0.0004 0.0022 0.0002 0 0.0008 0 0 0 0.0027 0.0007
Punctate Nuclear 0.0036 0 0.0016 0 0.0015 0.0927 0.0023 0 0.0003 0.0014 0.0009 0.0003 0.0026 0 0 0.0001 0.0009 0.0002
Vacuole 0.0011 0.0014 0.0024 0.0001 0.0043 0.0536 0.0058 0.001 0.0013 0.0311 0.005 0.0007 0.0006 0.0001 0.0005 0.0005 0.0024 0.0008
Vacuole Periphery 0.0011 0.0003 0.0027 0.0001 0.0084 0.0149 0.0042 0.0001 0.0004 0.0082 0.0065 0.0003 0.0006 0 0.0001 0.0002 0.0024 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 223.0146 157.7849 165.4863 200.0931 171.3155 261.4905 228.5348 219.5631 202.478 199.089
Translational Efficiency 1.3813 1.5342 1.3082 1.1834 1.2213 1.3138 1.1371 0.869 0.9433 0.885

Hit Data

Dataset Hit
Protein Concentration
Protein Localization
Gene Expression
Translational Efficiency

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1741 1053 250 1257 1081 1812 642 334 2822 2865 892 1591

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 21296.64 24544.34 16208.66 6400.03 18667.01 31463.59 7972.92 12776.91 20289.33 28920.49 10281.14 7738.73
Standard Deviation 5512.07 5834.16 3299.26 1781.91 4049.30 7591.04 1741.51 3342.39 5163.29 7751.38 4349.21 3405.66
Intensity Change Log 2 0.204765 -0.393861 -1.734475 0.753192 -1.227311 -0.546952 0.486943 -0.724780 -1.059316

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000015 0.000040 0.000116 0.000132 0.000026 0.000034 0.000122 0.000505 0.000019 0.000037 0.000120 0.000210
Bud Neck 0.000071 0.000258 0.002678 0.002402 0.000198 0.000186 0.002596 0.002876 0.000120 0.000213 0.002619 0.002501
Bud Site 0.000226 0.000990 0.001128 0.006736 0.000603 0.000554 0.002326 0.007820 0.000371 0.000714 0.001990 0.006963
Cell Periphery 0.000777 0.003652 0.028842 0.004678 0.005361 0.003558 0.019988 0.045014 0.002533 0.003593 0.022470 0.013146
Cytoplasm 0.890136 0.861544 0.636057 0.821510 0.895740 0.883229 0.745294 0.635536 0.892283 0.875259 0.714678 0.782468
Cytoplasmic Foci 0.001776 0.004774 0.030157 0.004736 0.004358 0.003586 0.012607 0.006827 0.002765 0.004022 0.017525 0.005175
Eisosomes 0.000000 0.000001 0.000008 0.000002 0.000001 0.000001 0.000004 0.000012 0.000001 0.000001 0.000005 0.000004
Endoplasmic Reticulum 0.000007 0.000017 0.000033 0.000091 0.000024 0.000016 0.000066 0.000325 0.000013 0.000016 0.000056 0.000140
Endosome 0.000010 0.000029 0.000107 0.000625 0.000027 0.000019 0.000221 0.003038 0.000017 0.000022 0.000189 0.001131
Golgi 0.001561 0.001544 0.007234 0.002941 0.003118 0.001177 0.010338 0.004139 0.002157 0.001312 0.009468 0.003193
Lipid Particles 0.000362 0.001544 0.009105 0.005981 0.002025 0.001195 0.015156 0.025436 0.000999 0.001323 0.013460 0.010065
Mitochondria 0.000088 0.000088 0.000169 0.000553 0.000082 0.000103 0.000107 0.002592 0.000086 0.000097 0.000124 0.000981
Mitotic Spindle 0.000118 0.000219 0.000509 0.002105 0.000105 0.000097 0.001363 0.002468 0.000113 0.000141 0.001124 0.002181
None 0.017750 0.010496 0.006617 0.003917 0.013451 0.015140 0.002682 0.001820 0.016103 0.013433 0.003785 0.003477
Nuclear Periphery 0.000091 0.000155 0.002312 0.000199 0.000189 0.000121 0.001191 0.000545 0.000128 0.000134 0.001505 0.000272
Nuclear Periphery Foci 0.000738 0.001189 0.003998 0.002286 0.001715 0.000879 0.007265 0.003904 0.001112 0.000993 0.006349 0.002626
Nucleolus 0.000159 0.000053 0.000093 0.000204 0.000042 0.000052 0.000076 0.000132 0.000114 0.000052 0.000081 0.000189
Nucleus 0.082200 0.099958 0.202212 0.053914 0.060465 0.078976 0.073639 0.031264 0.073874 0.086688 0.109674 0.049159
Peroxisomes 0.000012 0.000007 0.000006 0.000053 0.000008 0.000006 0.000009 0.000130 0.000010 0.000006 0.000008 0.000069
Vacuole 0.002728 0.011935 0.061690 0.083764 0.010794 0.010062 0.097345 0.220669 0.005818 0.010750 0.087352 0.112505
Vacuole Periphery 0.001176 0.001509 0.006928 0.003171 0.001669 0.001010 0.007606 0.004949 0.001365 0.001193 0.007416 0.003544

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -4.66 -8.39 -10.72 -7.51 0.03 -1.50 -11.58 -2.36 -2.32 -1.56 -4.97 -14.63 -5.10 -4.55 -1.29
Bud Neck -6.75 -6.55 -9.79 -9.00 0.29 0.48 -7.13 -5.09 -5.12 0.68 -5.06 -9.32 -10.91 -10.48 0.57
Bud Site -4.75 -5.92 -8.37 -7.16 -6.88 0.67 -6.12 -5.65 -5.80 -4.03 -3.02 -8.72 -9.78 -9.26 -6.69
Cell Periphery -5.27 -8.38 -7.39 0.17 7.47 2.22 -8.37 -7.57 -8.15 -3.68 -2.72 -13.29 -8.03 -6.68 7.10
Cytoplasm 6.88 17.50 17.43 10.51 -9.71 2.32 15.94 16.17 15.63 4.42 6.00 22.73 22.76 19.12 -5.68
Cytoplasmic Foci -5.93 -9.48 -7.38 -0.91 8.09 1.25 -7.92 -2.49 -3.19 3.70 -3.88 -13.14 -6.30 -3.67 9.80
Eisosomes -4.35 -6.91 -9.40 -6.77 5.15 1.01 -9.26 -3.34 -3.42 -1.92 -2.41 -11.71 -5.92 -5.50 2.58
Endoplasmic Reticulum -3.56 -6.05 -3.47 -2.89 -1.71 1.79 -6.66 -1.15 -1.20 -0.88 -1.51 -10.39 -2.33 -2.25 -1.08
Endosome -3.37 -6.48 -3.31 -3.17 -2.51 1.55 -8.54 -1.21 -1.21 -1.06 -1.96 -10.17 -2.26 -2.24 -1.65
Golgi -0.01 -6.70 -2.08 -2.58 5.59 3.41 -7.91 -0.29 -4.15 7.99 2.48 -11.35 -1.38 -4.26 10.56
Lipid Particles -4.81 -6.52 -10.08 -7.40 2.08 2.12 -9.58 -7.85 -8.22 -2.04 -1.95 -12.01 -11.91 -11.31 3.27
Mitochondria -0.13 -3.67 -1.19 -1.18 -0.76 -1.91 -4.54 -1.07 -1.06 -1.04 -0.91 -3.79 -1.53 -1.49 -1.36
Mitotic Spindle -1.17 -2.87 -2.63 -2.50 -2.04 -0.03 -3.77 -1.19 -1.19 0.03 -0.73 -4.10 -2.89 -2.84 -0.97
None 5.87 8.99 13.03 7.58 2.91 -1.06 9.20 9.54 12.36 2.20 2.80 15.35 15.41 13.06 1.65
Nuclear Periphery -2.19 -7.32 -4.36 -2.99 6.86 2.78 -8.08 -5.11 -6.63 5.58 -0.66 -11.04 -5.96 -7.24 9.81
Nuclear Periphery Foci -2.20 -5.95 -7.08 -5.00 2.88 3.15 -9.48 -4.44 -7.08 6.12 0.23 -11.87 -7.64 -8.41 7.95
Nucleolus 0.79 0.42 -0.45 -6.87 -4.69 -1.04 -6.24 -3.75 -3.27 -1.86 0.74 0.23 -1.06 -7.47 -5.47
Nucleus -5.04 -12.42 3.33 7.29 13.40 -5.24 -5.08 4.59 9.18 8.36 -5.76 -9.90 3.63 8.37 11.50
Peroxisomes 0.50 0.48 -2.87 -5.43 -5.49 0.83 -1.27 -2.25 -2.30 -2.18 0.67 0.14 -4.02 -5.14 -4.82
Vacuole -6.73 -8.73 -22.42 -19.02 -4.11 0.80 -14.13 -16.99 -17.18 -8.50 -4.89 -17.24 -26.77 -25.40 -5.32
Vacuole Periphery -0.39 -3.78 -2.72 -1.26 2.86 1.38 -6.23 -2.58 -3.49 3.06 0.49 -7.72 -3.36 -3.33 5.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Componentsactinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Large subunit of carbamoyl phosphate synthetase; carbamoyl phosphate synthetase catalyzes a step in the synthesis of citrulline, an arginine precursor
Localization
Cell Percentages cytoplasm (95%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Cpa2

Cpa2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)

Molecular Function (Gene Ontology)

Cellular Component (Gene Ontology)


Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cpa2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available