Standard name
Human Ortholog
Description Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0.05 0 0 0.06 0 0 0 0.07 0.15 0.26 0.14 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0.09 0 0.1 0.07 0.1 0 0.09 0.1 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0 0.14 0 0 0.06 0.07 0.12 0.06 0.06 0.07 0.06 0.07 0.07 0.12 0 0 0 0 0 0.05
Nucleus 0.87 0.89 0.84 0.08 0.1 0.12 0.11 0.12 0.18 0.11 0.15 0.14 0.3 0.08 0.06 0.25 0.33 0.31 0.66 0.73 0.57 0.38 0.25 0.21
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.16 0.12 0.16 0.9 0.83 0.77 0.79 0.79 0.72 0.76 0.74 0.76 0.69 0.87 0.76 0.43 0.47 0.58 0.28 0.19 0.36 0.37 0.51 0.47
Peroxisomes 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0.17 0.18 0.23 0.16 0.12 0.14 0.13 0.13 0 0 0.05 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.08 0 0 0.05 0 0.21 0.16 0.18
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 1 0 0 2 0 0 2 0 1 0 0 0 0 0 1 1 1 3 4
Bud Neck 0 0 0 0 4 1 0 1 0 0 5 1 0 0 0 0 0 0 0 0 0 0 1 0
Bud Site 0 0 0 0 0 4 1 4 5 1 12 8 0 1 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 6 6 2 4 7 2 17 6 4 14 10 11 8 19 51 49 23 9 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 5 4 3 0 0 0 0 0 0
Endosome 0 0 0 6 23 5 32 22 25 11 38 48 0 3 6 1 0 0 0 0 1 0 1 6
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 1 0 2
Mitochondria 0 2 0 13 3 30 5 8 15 19 52 29 15 21 21 14 12 14 1 1 0 1 11 13
Nucleus 241 380 134 15 26 25 37 38 46 29 68 68 77 23 20 47 53 37 194 349 106 93 88 60
Nuclear Periphery 0 3 0 0 3 2 7 3 1 3 5 3 0 0 0 0 0 0 1 1 0 1 3 3
Nucleolus 44 51 25 162 214 160 256 248 184 194 331 362 179 252 262 82 76 69 83 91 67 89 181 136
Peroxisomes 0 0 0 1 11 7 19 10 5 7 16 13 2 1 6 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 11 44 38 74 50 30 35 57 60 2 8 17 1 2 0 0 1 0 1 6 5
Vac/Vac Membrane 7 6 3 0 6 4 6 4 5 3 8 9 1 0 5 10 13 4 10 23 7 52 57 50
Unique Cell Count 276 426 159 180 259 209 326 313 254 254 445 476 258 291 343 190 162 119 293 477 187 245 359 289
Labelled Cell Count 298 448 164 212 342 279 454 394 322 316 602 614 284 329 388 210 184 136 293 477 187 245 359 289


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 26.1 24.8 23.1 21.8 19.3 11.0 14.7 13.7 13.0 12.8 13.1 12.9 26.9 24.6 22.4 30.1 32.6 34.3 23.4 23.9 23.4
Std Deviation (1e-4) 7.4 7.5 5.3 6.7 8.2 4.0 4.4 4.2 3.6 3.7 4.6 4.1 9.4 10.2 12.9 20.8 18.9 17.0 7.9 9.0 7.0
Intensity Change (Log2) – – – -0.09 -0.27 -1.07 -0.65 -0.75 -0.83 -0.85 -0.83 -0.84 0.22 0.09 -0.04 0.38 0.49 0.57 0.02 0.04 0.02

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002040WT3HU80HU120HU16002040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302040WT1AF100AF140AF18002040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 2.1 0 0 2.2 0 0 0 2.5 4.6 6.5 4.3 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 3.9 0 4.1 3.4 4.1 0 3.8 4.2 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.5 0 5.0 0 0 3.1 3.5 4.5 3.2 3.1 3.5 3.2 3.5 3.5 4.4
Nucleus -14.1 -15.2 -13.9 -15.8 -15.4 -13.2 -14.7 -15.8 -16.4 -10.8 -16.2 -17.7 -11.1 -9.4 -9.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 13.7 13.4 11.6 13.2 13.2 11.2 12.0 12.9 13.5 10.6 14.8 12.8 5.5 6.0 7.4
Peroxisomes 0 0 0 3.1 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 3.2 5.5 5.7 6.5 5.3 4.5 4.9 4.7 4.7 0 0 2.9 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 1.7 2.5 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 22.4188 26.8528 24.1648 20.5648 19.9499 23.4364 30.1265 34.8622 31.3838 28.313 29.9956 30.2205 30.1334 32.9984 29.6618 29.3721 24.7569 28.8015
Actin 0.0007 0.0001 0.0015 0.0002 0.0097 0.0003 0.0027 0 0 0.0092 0.0001 0.0031 0 0 0 0 0.0006 0
Bud 0.0003 0 0.0001 0.0002 0.0001 0.0001 0.0002 0 0.0004 0.0006 0.0001 0.0001 0 0 0 0 0.0001 0
Bud Neck 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0005 0.0001 0.0003 0 0.0001 0 0.0001 0.0001 0.0002
Bud Periphery 0.0004 0.0001 0.0001 0.0004 0.0004 0.0003 0.0003 0.0001 0.0002 0.0008 0.0001 0.0003 0 0.0001 0 0.0001 0.0001 0.0002
Bud Site 0.0014 0 0.0002 0.0004 0.0002 0.0001 0.0005 0.0001 0.0005 0.0013 0.0001 0.0001 0.0001 0 0 0 0.0005 0
Cell Periphery 0.0003 0.0002 0.0002 0.0005 0.0002 0.0008 0.0007 0.0008 0.0009 0.0005 0.0003 0.0009 0.0001 0.0004 0.0001 0.0001 0.0001 0.0004
Cytoplasm 0.0013 0 0.0004 0.0001 0.0219 0.0002 0.0021 0 0.0012 0.0164 0.0002 0.0001 0 0 0 0 0.0006 0
Cytoplasmic Foci 0.0084 0 0.0053 0.0003 0.0024 0.005 0.0073 0 0.0085 0.0018 0.0013 0.0024 0.0001 0 0 0.0002 0.0057 0
Eisosomes 0.0001 0 0.0001 0 0.0001 0 0.0001 0 0 0.0001 0.0001 0.0001 0 0 0 0 0.0002 0
Endoplasmic Reticulum 0.0007 0 0.0002 0.0001 0.0006 0.0001 0.0004 0 0 0.002 0 0.0001 0 0 0 0 0.0001 0
Endosome 0.0099 0 0.0078 0.0003 0.0073 0.0026 0.0053 0 0.0011 0.0227 0 0.0004 0 0 0 0 0.0002 0
Golgi 0.001 0 0.0019 0 0.0133 0.0009 0.006 0 0.0004 0.0072 0 0.0004 0 0 0 0 0.0002 0
Lipid Particles 0.0061 0.0001 0.0071 0.0008 0.0107 0.0015 0.0058 0.0001 0.0013 0.0015 0.0008 0.0037 0.0006 0 0.0001 0.0001 0.0022 0.0004
Mitochondria 0.003 0.0006 0.0053 0.0042 0.0291 0.0104 0.0066 0.0007 0.0035 0.0018 0.005 0.0109 0.001 0.0004 0.0002 0.0007 0.0048 0.001
None 0.001 0 0.0022 0.0002 0.0266 0.0001 0.0012 0 0.0001 0.0002 0.0005 0.0001 0 0 0 0 0.0028 0
Nuclear Periphery 0.0071 0.0039 0.0036 0.0441 0.0634 0.0122 0.0076 0.0051 0.0028 0.0108 0.0081 0.0092 0.0003 0.0015 0.0014 0.0036 0.0016 0.0079
Nucleolus 0.716 0.6603 0.8025 0.7153 0.4405 0.756 0.632 0.6072 0.7075 0.5528 0.5166 0.6801 0.7622 0.7152 0.8425 0.566 0.6734 0.7332
Nucleus 0.2259 0.332 0.1514 0.2222 0.359 0.1913 0.3091 0.378 0.2654 0.3649 0.4598 0.2722 0.2349 0.2795 0.1547 0.4265 0.2943 0.2535
Peroxisomes 0.0004 0 0.001 0.0001 0.0023 0.0001 0.0013 0 0.0008 0.0002 0.0001 0.0035 0 0 0 0 0.0004 0
Punctate Nuclear 0.0104 0.0004 0.0047 0.0016 0.0045 0.0014 0.0023 0.0003 0.0004 0.0005 0.0007 0.0007 0.0003 0.0001 0.0004 0.0004 0.0106 0.0004
Vacuole 0.0025 0.0005 0.0009 0.0017 0.0011 0.0024 0.0028 0.0018 0.0028 0.0018 0.001 0.002 0.0002 0.0012 0.0001 0.0005 0.0003 0.0007
Vacuole Periphery 0.003 0.0015 0.0036 0.0073 0.0064 0.0141 0.0056 0.0056 0.0018 0.0022 0.0049 0.0094 0.0003 0.0014 0.0004 0.0014 0.0009 0.002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 100.8738 91.5623 71.0315 92.5085 85.5148 72.8992 84.8637 55.8572 47.9361 94.718
Translational Efficiency 3.1464 3.3624 3.215 1.6574 2.6255 2.84 2.2467 2.4669 2.4111 2.0656

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2045 1162 128 1231 719 1958 2929 1134 2764 3120 3057 2365

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1525.16 1818.50 2200.07 2494.20 1569.03 1961.33 2577.33 2590.60 1536.57 1908.13 2561.53 2540.42
Standard Deviation 378.95 493.89 578.63 742.75 367.96 657.90 684.09 761.10 376.62 606.01 684.19 753.14
Intensity Change Log 2 — 0.253788 0.528589 0.709617 — 0.321959 0.716004 0.723413 — 0.288760 0.626664 0.716629

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000701 0.000671 0.000974 0.001149 0.000535 0.000584 0.001102 0.001361 0.000658 0.000617 0.001097 0.001251
Bud Neck 0.002398 0.003348 0.008394 0.015363 0.001986 0.003597 0.003676 0.008302 0.002291 0.003504 0.003874 0.011977
Bud Site 0.000222 0.000469 0.000702 0.003530 0.000144 0.000354 0.000207 0.002332 0.000201 0.000397 0.000228 0.002956
Cell Periphery 0.000130 0.000057 0.000020 0.000233 0.000015 0.000109 0.000043 0.000259 0.000100 0.000090 0.000042 0.000245
Cytoplasm 0.000232 0.000164 0.000282 0.001156 0.000029 0.000065 0.000086 0.000864 0.000179 0.000102 0.000094 0.001016
Cytoplasmic Foci 0.000338 0.000359 0.000482 0.005263 0.000276 0.000065 0.000244 0.004566 0.000322 0.000174 0.000254 0.004929
Eisosomes 0.000133 0.000128 0.000101 0.000101 0.000072 0.000168 0.000095 0.000109 0.000117 0.000153 0.000096 0.000105
Endoplasmic Reticulum 0.001459 0.000277 0.000224 0.000471 0.000438 0.000502 0.000311 0.000416 0.001193 0.000418 0.000307 0.000444
Endosome 0.000025 0.000042 0.000016 0.003120 0.000019 0.000066 0.000011 0.002782 0.000023 0.000057 0.000011 0.002958
Golgi 0.000020 0.000095 0.000132 0.003498 0.000068 0.000040 0.000045 0.002106 0.000032 0.000060 0.000049 0.002831
Lipid Particles 0.000003 0.000014 0.000014 0.000835 0.000011 0.000009 0.000003 0.000720 0.000005 0.000011 0.000004 0.000780
Mitochondria 0.000783 0.001545 0.002804 0.007036 0.001196 0.001031 0.002206 0.007998 0.000890 0.001222 0.002231 0.007497
Mitotic Spindle 0.000037 0.000271 0.000168 0.011304 0.000105 0.000987 0.000039 0.005016 0.000055 0.000720 0.000044 0.008289
None 0.000742 0.001168 0.000723 0.001480 0.000627 0.000594 0.000899 0.001393 0.000712 0.000808 0.000892 0.001438
Nuclear Periphery 0.000350 0.000119 0.000116 0.002351 0.000185 0.000349 0.001364 0.003424 0.000307 0.000263 0.001312 0.002865
Nuclear Periphery Foci 0.000022 0.000160 0.000029 0.000883 0.000175 0.000209 0.000076 0.001431 0.000062 0.000191 0.000074 0.001146
Nucleolus 0.136073 0.374083 0.402188 0.460422 0.462064 0.256075 0.260877 0.574457 0.220873 0.300025 0.266794 0.515101
Nucleus 0.853387 0.606435 0.561470 0.450321 0.522100 0.730796 0.719974 0.346809 0.767209 0.684479 0.713338 0.400687
Peroxisomes 0.001003 0.007986 0.020048 0.021763 0.008782 0.002327 0.002847 0.017575 0.003026 0.004434 0.003567 0.019755
Vacuole 0.000675 0.000852 0.000433 0.004872 0.000309 0.000588 0.000910 0.005081 0.000580 0.000686 0.000890 0.004972
Vacuole Periphery 0.001270 0.001757 0.000680 0.004847 0.000866 0.001486 0.004983 0.012999 0.001165 0.001587 0.004802 0.008756

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.91 -4.74 -10.56 -10.54 -1.78 -1.12 -18.44 -4.44 -4.09 -1.38 1.26 -16.42 -6.48 -6.72 -1.66
Bud Neck -2.40 -7.36 -15.08 -13.13 -6.52 -5.79 -8.69 -9.73 -7.28 -7.47 -5.41 -10.69 -17.64 -15.05 -15.03
Bud Site -1.64 -4.48 -6.54 -5.65 -5.34 -1.61 -0.45 -4.52 -4.14 -4.50 -2.13 -0.47 -7.89 -7.16 -7.87
Cell Periphery 1.08 1.71 -1.79 -5.01 -6.75 -2.34 -5.69 -5.49 -2.69 -4.90 0.17 1.23 -3.04 -4.51 -7.67
Cytoplasm 0.38 -0.65 -4.82 -6.30 -0.98 -1.34 -2.90 -3.87 -3.74 -3.67 0.73 0.73 -5.30 -7.16 -7.14
Cytoplasmic Foci -0.06 -0.49 -6.46 -6.83 -6.63 1.20 0.71 -4.92 -6.18 -5.91 0.97 0.63 -8.16 -9.32 -9.15
Eisosomes 0.33 1.75 2.77 2.59 0.57 -7.43 -4.98 -5.95 4.24 -2.14 -3.22 2.54 1.32 5.10 -1.99
Endoplasmic Reticulum 12.54 13.05 7.93 -2.15 -2.57 -0.78 2.99 0.16 0.63 -1.00 9.40 12.69 7.70 -0.32 -1.99
Endosome -1.48 1.84 -3.94 -3.91 -3.95 -2.12 2.23 -3.90 -3.83 -3.91 -2.49 4.09 -5.54 -5.46 -5.57
Golgi -2.99 -10.07 -3.05 -2.97 -2.93 1.91 1.75 -2.62 -2.67 -2.67 -2.28 -2.21 -4.02 -3.98 -4.00
Lipid Particles -2.60 -4.93 -1.51 -1.49 -1.49 0.72 1.70 -1.52 -1.53 -1.54 -1.72 1.32 -2.15 -2.13 -2.15
Mitochondria -6.56 -10.04 -11.97 -10.29 -7.36 0.91 -7.01 -5.56 -5.68 -4.73 -3.78 -14.01 -10.28 -9.68 -8.10
Mitotic Spindle -1.33 -1.69 -5.83 -5.70 -5.75 -1.16 1.06 -4.11 -2.99 -4.30 -1.49 0.91 -7.11 -6.17 -7.18
None -1.80 -0.18 -4.62 -1.87 -6.32 0.15 -0.96 -3.51 -3.49 -1.63 -0.64 -0.68 -5.09 -4.46 -2.30
Nuclear Periphery 4.40 4.35 -3.75 -4.23 -4.23 -1.13 -4.88 -4.39 -4.06 -2.62 0.36 -4.31 -5.67 -5.65 -2.99
Nuclear Periphery Foci -1.99 -0.86 -4.10 -3.13 -4.06 -0.17 1.82 -3.23 -3.04 -3.61 -1.52 -0.31 -5.06 -4.08 -5.05
Nucleolus -23.60 -9.37 -28.30 -5.10 -1.79 16.28 16.38 -7.49 -27.96 -28.64 -10.70 -6.16 -32.59 -23.49 -27.24
Nucleus 24.08 10.07 35.42 10.46 3.60 -16.29 -15.91 11.97 34.66 35.11 11.00 7.10 41.27 31.72 34.94
Peroxisomes -10.69 -6.68 -13.78 -8.64 -0.65 6.31 5.71 -5.33 -12.33 -11.76 -3.25 -1.17 -16.27 -15.25 -16.02
Vacuole -0.96 1.83 -3.97 -3.41 -4.17 -2.33 -5.98 -5.65 -5.30 -4.95 -1.07 -2.84 -6.50 -6.10 -6.01
Vacuole Periphery -1.83 5.41 -5.67 -4.42 -6.80 -2.50 -12.42 -8.82 -8.27 -5.65 -2.34 -11.89 -10.18 -9.37 -4.74
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein involved in mRNA turnover and ribosome assembly; required at post-transcriptional step for efficient retrotransposition; localizes to the nucleolus
Localization
Cell Percentages nucleus (88%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Mrt4

Mrt4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrt4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available