Standard name
Human Ortholog
Description TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0.05 0.05 0 0 0 0 0 0 0 0.05 0.08 0.11 0.08 0.05 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.06 0.05 0 0 0.13 0.08 0.15 0.2 0.19 0.19 0.25 0 0 0 0.05 0 0 0 0 0 0 0 0
Nucleus 0.95 0.92 0.93 0.91 0.91 0.89 0.85 0.78 0.8 0.77 0.73 0.76 0.94 0.85 0.77 0.83 0.9 0.83 0.92 0.91 0.92 0.91 0.77 0.69
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.18 0.15 0.16 0.1 0.08 0.14 0.17 0.25 0.22 0.33 0.45 0.26 0.08 0.08 0.15 0.05 0 0 0 0 0 0 0.1 0.12
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.15
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1
Bud 0 0 0 0 0 0 0 1 1 1 1 1 1 1 1 0 0 0 1 2 0 0 2 11
Bud Neck 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 1 0 2 1 3 6 7 2 10 1 1 6 1 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0
Cytoplasm 5 6 3 8 16 6 14 30 12 16 5 13 30 84 114 32 16 24 1 1 0 0 2 2
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 4 0 0 0 0 0 1
Endosome 0 0 1 1 0 0 0 1 0 0 1 0 1 7 16 7 4 0 0 0 1 1 8 9
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 2 2 1
Mitochondria 6 11 8 6 8 42 41 102 76 123 55 116 0 2 0 18 3 4 1 1 0 1 4 5
Nucleus 232 165 143 151 288 287 440 551 310 513 207 356 612 850 831 320 281 204 222 170 146 509 662 730
Nuclear Periphery 0 0 0 0 0 1 2 1 1 10 1 6 0 0 0 4 0 0 0 0 0 0 0 2
Nucleolus 44 27 24 17 25 45 86 177 84 216 127 120 54 84 157 18 14 11 7 1 4 23 87 122
Peroxisomes 0 0 0 0 0 0 1 0 0 0 0 0 3 11 14 4 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 0 0 1 0 0 0 0 0 3 27 32 3 0 1 1 0 0 0 3 3
Vac/Vac Membrane 0 3 0 1 2 3 2 7 4 0 1 3 1 9 22 8 6 9 4 5 5 15 77 161
Unique Cell Count 243 180 153 166 316 321 518 703 388 664 283 470 653 1003 1078 384 313 246 243 187 159 559 858 1064
Labelled Cell Count 287 212 179 186 339 386 588 873 494 886 401 625 706 1078 1193 418 325 258 243 187 159 559 858 1064


Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.3 9.3 8.5 9.0 8.9 7.4 7.4 6.9 7.0 6.5 6.3 6.2 13.0 12.0 11.8 10.5 13.5 14.5 11.4 10.8 11.8
Std Deviation (1e-4) 2.2 2.5 1.7 2.0 1.8 1.6 1.6 1.5 1.7 1.5 1.6 1.6 3.5 3.7 3.9 3.3 3.8 3.8 2.3 2.2 2.3
Intensity Change (Log2) – – – 0.08 0.06 -0.21 -0.19 -0.3 -0.28 -0.39 -0.42 -0.45 0.61 0.5 0.47 0.31 0.67 0.77 0.43 0.35 0.47

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 1.6 0 0 1.3 0 0 0 0 1.5 2.8 3.4 2.7 1.6 3.0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -0.7 -1.5 2.6 1.1 3.1 4.2 4.0 4.0 5.2 0 0 0 -0.3 0 0
Nucleus -0.8 -0.9 -1.4 -2.7 -4.3 -3.9 -4.5 -5.1 -4.8 0.1 -2.9 -4.7 -3.1 -1.3 -3.0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus -1.5 -2.6 -0.5 0.3 2.5 1.6 4.1 6.1 2.5 -2.8 -2.9 -0.4 -4.3 -4.2 -3.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 12.7793 12.4744 12.1278 11.6448 11.2601 11.8943 6.184 6.0409 5.9775 6.2954 3.1755 6.1234 7.213 7.1756 6.7525 7.6457 7.4812 7.926
Actin 0.0005 0 0.0014 0.0001 0.0019 0.0003 0.005 0 0.0194 0 0.0908 0.015 0.007 0 0.0238 0 0 0
Bud 0.0002 0 0.0001 0 0.0001 0 0.0008 0 0.0001 0 0.0011 0 0.0005 0 0.0002 0 0 0
Bud Neck 0.0002 0 0.0005 0 0.0005 0.0004 0.0003 0.0001 0.0001 0.0002 0.0007 0.0003 0.0009 0.0001 0.0004 0 0.0002 0.0004
Bud Periphery 0.0004 0 0.0001 0 0.0001 0 0.0009 0 0.0001 0 0.001 0 0.0012 0 0.0005 0 0.0001 0.0001
Bud Site 0.0004 0 0.0014 0 0.0006 0.0001 0.0017 0.0002 0.0011 0 0.0028 0.0001 0.0008 0.0001 0.0016 0 0 0
Cell Periphery 0.0002 0 0.0001 0 0 0 0.0005 0 0 0 0.0001 0 0.0006 0.0001 0.0002 0 0 0
Cytoplasm 0.003 0 0.0016 0.0001 0.0006 0.0003 0.0079 0.0247 0.0008 0 0.0052 0 0.0028 0.0072 0.0004 0.0001 0 0
Cytoplasmic Foci 0.0043 0 0.0008 0.0028 0.0079 0.0001 0.0361 0.0002 0.0089 0 0.0296 0.0004 0.0072 0.0001 0.0108 0 0 0
Eisosomes 0 0 0 0 0 0 0 0 0.0001 0 0.0003 0.0001 0.0001 0 0.0002 0 0 0
Endoplasmic Reticulum 0.0004 0 0.0019 0.0001 0.0002 0.0002 0.0018 0.0002 0.0002 0 0.0035 0.0001 0.005 0.0002 0.0007 0 0 0
Endosome 0.0012 0 0.0034 0.0005 0.0066 0.0001 0.0074 0.0019 0.0078 0 0.045 0.0003 0.015 0.0005 0.0036 0 0 0
Golgi 0.0003 0 0.0007 0.0003 0.0049 0 0.0029 0 0.003 0 0.0243 0.0006 0.0017 0 0.0013 0 0 0
Lipid Particles 0.0038 0 0.0006 0.0041 0.0064 0.0001 0.022 0 0.0027 0 0.0113 0.0007 0.0026 0 0.0041 0 0 0
Mitochondria 0.0019 0.0001 0.0007 0 0.0023 0.0005 0.0032 0.0001 0.0006 0.0002 0.0093 0.0001 0.0017 0.0002 0.0099 0 0.0003 0.0002
None 0.0011 0 0.0002 0.0001 0.0002 0.0005 0.0032 0.0003 0.0209 0 0.0033 0.0001 0.0018 0.0001 0.0006 0 0 0
Nuclear Periphery 0.0032 0.0015 0.0031 0.0035 0.0029 0.0008 0.0236 0.0036 0.0013 0.0016 0.0054 0.0003 0.0142 0.0051 0.0065 0.0031 0.0006 0.0001
Nucleolus 0.0456 0.0162 0.0136 0.0077 0.1068 0.0779 0.0188 0.0111 0.0052 0.0626 0.0609 0.0485 0.0536 0.0199 0.0186 0.0052 0.0779 0.0502
Nucleus 0.9247 0.9809 0.9659 0.9528 0.8469 0.9175 0.8018 0.9418 0.9239 0.9348 0.6874 0.9323 0.8424 0.9576 0.9046 0.9908 0.9201 0.9486
Peroxisomes 0.0002 0 0.0001 0.0001 0.005 0 0.0176 0 0.0028 0 0.0117 0.0005 0.0031 0 0.0052 0 0 0
Punctate Nuclear 0.0055 0.0011 0.0027 0.0278 0.0054 0.0009 0.0215 0.0007 0.0006 0.0003 0.0045 0.0004 0.0333 0.0014 0.0031 0.0001 0.0004 0.0001
Vacuole 0.0017 0 0.0008 0 0.0004 0.0001 0.0132 0.0138 0.0002 0.0001 0.0008 0 0.0031 0.0063 0.0016 0.0003 0.0001 0.0001
Vacuole Periphery 0.0013 0 0.0003 0 0.0003 0.0001 0.0097 0.0012 0.0001 0.0001 0.0009 0 0.0015 0.0011 0.0022 0.0002 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 32.3635 40.163 36.8745 38.1747 36.5305 31.965 33.7259 41.3445 47.6491 35.0598
Translational Efficiency 0.8855 0.8267 0.7565 1.0403 0.7643 0.873 0.8133 0.6865 0.5929 0.6961

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
932 1198 1594 695 1056 1444 833 1566 1988 2642 2427 2261

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 834.92 954.74 1207.99 1033.79 1007.62 1006.34 1221.49 1667.09 926.66 982.94 1212.62 1472.42
Standard Deviation 249.69 295.44 244.57 396.47 226.90 271.24 279.58 574.17 252.99 283.64 257.20 601.70
Intensity Change Log 2 — 0.193470 0.532899 0.308233 — -0.001834 0.277690 0.726380 — 0.089952 0.398952 0.551734

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000595 0.000517 0.000466 0.000913 0.000403 0.000514 0.000551 0.000430 0.000493 0.000515 0.000496 0.000578
Bud Neck 0.002194 0.003568 0.007687 0.012975 0.002183 0.006035 0.006112 0.009516 0.002188 0.004916 0.007147 0.010579
Bud Site 0.002674 0.000807 0.000430 0.008475 0.000255 0.001246 0.000557 0.001198 0.001389 0.001047 0.000473 0.003435
Cell Periphery 0.000397 0.000208 0.000032 0.000787 0.000076 0.000361 0.000053 0.000538 0.000226 0.000291 0.000039 0.000614
Cytoplasm 0.005986 0.002368 0.000058 0.010973 0.000085 0.001086 0.000256 0.005006 0.002851 0.001668 0.000126 0.006840
Cytoplasmic Foci 0.001185 0.000368 0.000013 0.002460 0.000019 0.000435 0.000035 0.000086 0.000566 0.000405 0.000020 0.000816
Eisosomes 0.000067 0.000064 0.000069 0.000902 0.000094 0.000086 0.000060 0.000073 0.000081 0.000076 0.000065 0.000328
Endoplasmic Reticulum 0.002122 0.001775 0.000678 0.001607 0.001441 0.002131 0.001029 0.002423 0.001760 0.001969 0.000798 0.002172
Endosome 0.000198 0.000216 0.000014 0.000795 0.000024 0.000303 0.000029 0.000118 0.000105 0.000263 0.000019 0.000326
Golgi 0.000095 0.000143 0.000026 0.001880 0.000022 0.000181 0.000034 0.000032 0.000056 0.000164 0.000029 0.000600
Lipid Particles 0.000198 0.000586 0.000004 0.002634 0.000005 0.000232 0.000010 0.000015 0.000095 0.000392 0.000006 0.000820
Mitochondria 0.000623 0.000940 0.000873 0.002759 0.000526 0.001656 0.001005 0.000899 0.000571 0.001331 0.000919 0.001471
Mitotic Spindle 0.000179 0.000068 0.000041 0.004284 0.000013 0.001276 0.000125 0.000123 0.000090 0.000728 0.000070 0.001402
None 0.018897 0.014786 0.000600 0.047807 0.002399 0.014628 0.003404 0.009676 0.010133 0.014700 0.001562 0.021397
Nuclear Periphery 0.000051 0.000196 0.000045 0.000894 0.000022 0.000172 0.000067 0.000327 0.000035 0.000183 0.000053 0.000501
Nuclear Periphery Foci 0.001396 0.000299 0.000004 0.003423 0.000019 0.000499 0.000019 0.000478 0.000665 0.000408 0.000009 0.001383
Nucleolus 0.046900 0.032120 0.017134 0.011474 0.028483 0.022651 0.015618 0.004344 0.037117 0.026944 0.016614 0.006536
Nucleus 0.911341 0.938471 0.970977 0.879283 0.962105 0.944522 0.970026 0.963447 0.938306 0.941778 0.970651 0.937576
Peroxisomes 0.003475 0.000973 0.000623 0.000651 0.000957 0.000530 0.000719 0.000057 0.002138 0.000731 0.000656 0.000239
Vacuole 0.000795 0.000854 0.000143 0.003744 0.000494 0.000958 0.000213 0.001017 0.000635 0.000911 0.000167 0.001855
Vacuole Periphery 0.000635 0.000676 0.000083 0.001280 0.000377 0.000500 0.000078 0.000197 0.000498 0.000580 0.000082 0.000530

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.98 1.44 -3.27 -5.15 -5.68 -2.90 -6.03 -1.09 1.51 2.94 -0.40 -0.21 -2.21 -2.35 -2.91
Bud Neck -3.22 -16.73 -6.47 -5.61 -3.36 -5.44 -10.07 -8.95 -3.44 -3.70 -6.30 -19.62 -10.94 -6.78 -4.46
Bud Site 2.39 3.01 -2.18 -3.22 -3.43 -3.01 -4.15 -3.71 0.06 -2.55 0.89 2.61 -2.31 -3.04 -4.04
Cell Periphery 1.81 3.78 -1.92 -3.57 -5.02 -3.40 1.51 -3.69 -1.16 -3.89 -0.91 4.06 -3.42 -2.81 -5.80
Cytoplasm 2.14 3.66 -1.85 -4.18 -5.61 -3.38 -4.09 -4.88 -3.91 -4.73 1.57 3.58 -3.35 -5.36 -7.24
Cytoplasmic Foci 2.13 3.19 -1.26 -2.46 -2.95 -2.24 -1.84 -1.63 1.65 -1.36 0.93 3.16 -0.67 -1.48 -3.14
Eisosomes 0.35 -0.14 -2.52 -2.53 -2.52 0.56 3.02 1.31 0.97 -0.94 0.62 2.11 -2.39 -2.44 -2.55
Endoplasmic Reticulum 1.83 11.58 2.63 0.70 -6.60 -3.34 3.94 -4.89 -0.98 -7.24 -1.47 12.47 -2.66 -1.03 -10.20
Endosome 0.03 2.69 -2.52 -2.53 -3.75 -4.07 -1.56 -3.41 2.51 -3.18 -2.39 2.67 -2.69 -0.58 -4.61
Golgi -0.48 3.72 -1.46 -1.42 -1.53 -1.77 -3.98 -2.18 1.63 0.27 -1.66 3.05 -1.45 -1.12 -1.54
Lipid Particles -0.71 1.22 -2.20 -1.70 -2.45 -1.96 -2.85 -1.92 1.87 -0.88 -1.19 1.20 -2.06 -1.00 -2.46
Mitochondria -2.06 -3.65 -2.97 -2.49 -2.59 -2.02 -6.15 -3.12 1.25 0.62 -2.42 -7.80 -3.85 -0.40 -2.28
Mitotic Spindle 0.86 0.94 -2.91 -2.98 -2.98 -2.27 -2.37 -1.58 1.93 -0.39 -2.02 0.18 -3.00 -1.85 -3.04
None 1.11 6.26 -3.56 -4.28 -6.86 -5.06 -0.77 -4.02 1.80 -3.19 -2.02 5.77 -3.69 -1.90 -8.10
Nuclear Periphery -1.24 0.43 -1.57 -1.25 -1.58 -2.66 -5.61 -5.34 -2.05 -4.50 -2.40 -3.57 -2.88 -1.83 -2.76
Nuclear Periphery Foci 2.09 2.63 -1.90 -3.14 -3.41 -2.72 -0.00 -3.07 -0.10 -3.07 1.07 2.64 -1.88 -3.00 -4.18
Nucleolus 3.90 8.33 8.93 7.18 1.95 2.14 4.77 10.59 9.82 6.47 4.42 9.31 14.42 13.35 8.01
Nucleus -4.04 -9.95 2.92 5.83 9.34 4.03 -2.23 0.20 -3.56 2.11 -0.93 -9.73 0.49 1.33 8.67
Peroxisomes 2.94 3.39 3.25 0.99 -0.57 3.05 1.64 7.52 6.70 9.31 3.45 3.66 4.68 4.43 6.60
Vacuole -0.02 4.32 -2.45 -2.39 -3.07 -1.98 2.57 -2.70 -0.16 -4.68 -1.30 5.16 -3.07 -2.22 -4.43
Vacuole Periphery -0.08 1.13 -0.77 -0.75 -2.02 -0.74 2.01 1.15 2.90 -3.32 -0.29 1.72 -0.03 0.31 -2.49
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description TFIIE large subunit; involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
Localization
Cell Percentages nucleus (98%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-2

Tfa1

Tfa1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tfa1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available