Standard name
Human Ortholog
Description UDP-glucose pyrophosphorylase (UGPase); catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p; involved in PKA-mediated oxidative stress resistance and long-term survival in stationary phase; UGP1 has a paralog, YHL012W, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0.05 0 0.08 0.05 0.07 0.05 0.08 0.1 0.05 0 0.05 0 0.07 0 0 0 0 0 0 0
Cytoplasm 0.99 0.99 0.99 0.99 0.97 0.94 0.88 0.86 0.85 0.85 0.79 0.85 1.0 0.99 0.99 0.95 0.96 0.97 0.99 0.97 0.9 0.94 0.95 0.93
Endoplasmic Reticulum 0 0 0 0 0 0.06 0.07 0.09 0.08 0.06 0.13 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0.05 0.07 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 1 2 5 5 3 6 6 0 0 0 0 0 0 0 0 1 0 1 1
Bud 0 2 0 0 0 1 0 0 3 0 2 0 1 1 0 1 0 0 0 1 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 14 7 3 9 5 15 12 11 6 13 17 18 19 19 13 14 6 0 0 0 0 0 0
Cytoplasm 144 432 141 147 175 175 168 202 142 111 129 148 370 447 410 295 205 172 142 423 132 199 376 260
Endoplasmic Reticulum 1 4 1 1 4 12 13 21 13 8 22 13 2 3 6 12 7 5 0 2 2 2 4 5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0
Golgi 0 1 0 0 0 0 1 0 1 1 2 0 0 0 0 0 1 0 0 0 0 0 1 1
Mitochondria 1 0 0 1 1 0 4 3 8 9 11 9 1 0 0 1 0 0 0 1 1 2 1 1
Nucleus 0 0 1 1 0 1 1 1 0 0 1 0 0 1 0 1 0 0 0 0 2 0 0 1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 1
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 1 0 1 1 1 0 2 6 0 2 1 1 0 2 0 16 5 3 0 1 1 0 1 3
Unique Cell Count 146 436 143 148 181 186 191 236 167 131 163 175 371 452 413 309 214 177 144 438 147 212 397 281
Labelled Cell Count 147 453 151 154 190 195 206 250 183 140 187 194 392 473 435 339 232 186 144 438 147 212 397 281


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 21.0 26.2 20.0 19.9 24.6 23.6 25.1 22.8 23.8 21.3 23.7 23.5 28.8 31.7 34.0 25.7 35.9 31.5 19.3 20.0 20.4
Std Deviation (1e-4) 4.3 5.2 4.5 4.2 6.0 6.6 6.8 6.7 6.7 7.0 7.2 7.6 7.4 9.2 10.5 8.7 11.2 11.1 5.1 4.4 4.6
Intensity Change (Log2) – – – -0.0 0.3 0.24 0.33 0.19 0.26 0.09 0.25 0.23 0.53 0.67 0.77 0.37 0.85 0.66 -0.05 0.0 0.03

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700010203040WT3HU80HU120HU160010203040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3010203040WT1AF100AF140AF180010203040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 -1.1 1.1 0.1 0.6 -0.1 1.1 1.6 0 -0.4 -0.1 -0.3 0.6 -0.7
Cytoplasm 0.6 -1.1 -2.1 -3.7 -4.2 -4.2 -4.2 -5.3 -4.3 1.5 0.3 0.7 -1.7 -1.5 -0.9
Endoplasmic Reticulum 0 0 2.7 2.8 3.3 3.0 0 4.2 2.9 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 3.2 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 2.3 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 24.1257 35.2858 32.1439 27.2064 29.223 34.7093 30.7131 40.1118 34.3381 34.1525 32.788 39.1637 32.9117 42.0043 39.187 38.1864 35.5131 38.4875
Actin 0.0348 0.0004 0.0037 0.103 0.064 0.0002 0.0059 0.0089 0.0148 0.0374 0.022 0.0003 0.005 0.0004 0.0031 0.0002 0.0019 0.0007
Bud 0.0008 0.0053 0.0013 0.0016 0.0007 0.0001 0.0009 0.0002 0.0007 0.001 0.0003 0.0001 0.0008 0.0024 0.0006 0.0003 0.0003 0.0002
Bud Neck 0.0011 0.0002 0.0009 0.0018 0.0007 0.0005 0.0005 0.0001 0.0004 0.0008 0.0004 0.0006 0.0004 0.0001 0.0003 0.0003 0.0003 0.0008
Bud Periphery 0.001 0.0015 0.0016 0.0018 0.0005 0 0.0008 0.0001 0.0004 0.0008 0.0003 0 0.0005 0.001 0.0014 0.0002 0.0002 0.0004
Bud Site 0.0019 0.0048 0.0054 0.0088 0.0022 0 0.001 0.0004 0.0009 0.0043 0.0005 0 0.0006 0.0007 0.0008 0.0002 0.0003 0.0001
Cell Periphery 0.0012 0.0001 0.0003 0.0003 0.0001 0 0.0001 0.0001 0.0002 0.0002 0.0001 0 0.0008 0.0002 0.0005 0.0002 0.0001 0.0002
Cytoplasm 0.7512 0.9677 0.9401 0.8124 0.8522 0.9574 0.8715 0.9824 0.8634 0.8929 0.851 0.9921 0.9044 0.9814 0.9621 0.9274 0.9125 0.9746
Cytoplasmic Foci 0.0145 0.0025 0.0162 0.0035 0.0177 0.0006 0.0346 0.0012 0.0099 0.0221 0.0094 0.0018 0.0129 0.0016 0.0063 0.0044 0.0169 0.0021
Eisosomes 0.0002 0 0.0001 0.0008 0.0006 0 0 0 0.0004 0.0002 0.0002 0 0.0003 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.0186 0.0006 0.0026 0.0011 0.001 0.0362 0.0052 0.0006 0.0031 0.0006 0.0014 0.0011 0.0101 0.0003 0.0016 0.0028 0.0035 0.0027
Endosome 0.0371 0.0014 0.0035 0.0043 0.007 0.0007 0.0242 0.0005 0.0183 0.0164 0.0053 0.0017 0.0072 0.0003 0.0033 0.0095 0.0057 0.0035
Golgi 0.0105 0.0003 0.0038 0.0091 0.0037 0 0.0109 0.0009 0.0387 0.0078 0.0258 0.0001 0.0026 0.0001 0.0006 0.0004 0.0013 0.0012
Lipid Particles 0.0124 0.0001 0.0017 0.0029 0.0089 0 0.0026 0.0003 0.004 0.0015 0.0021 0 0.0055 0.0001 0.0028 0.0017 0.0066 0.0017
Mitochondria 0.0076 0.0002 0.0027 0.0392 0.022 0.0002 0.0084 0.0019 0.0197 0.0065 0.0736 0.0001 0.0048 0.0086 0.0039 0.0015 0.0033 0.0004
None 0.02 0.009 0.0047 0.0003 0.0012 0.0001 0.0036 0.0002 0.0015 0.0005 0.0002 0.0002 0.0069 0.0004 0.0032 0.0018 0.0065 0.0003
Nuclear Periphery 0.0364 0.0007 0.001 0.0016 0.0029 0.0016 0.0068 0.0002 0.0152 0.0004 0.0004 0.0004 0.0048 0.0003 0.0012 0.0206 0.0077 0.0013
Nucleolus 0.001 0.0002 0.0002 0.0001 0.001 0 0.0005 0 0.0001 0.0001 0 0 0.0015 0.0001 0.0005 0.001 0.0007 0.0001
Nucleus 0.0141 0.0025 0.0017 0.0016 0.0024 0.0015 0.0084 0.0005 0.0029 0.0009 0.0007 0.0008 0.0104 0.0008 0.0016 0.0106 0.0057 0.003
Peroxisomes 0.0062 0 0.0027 0.0038 0.0031 0 0.0069 0.0012 0.0027 0.0019 0.0054 0 0.0033 0.0002 0.0006 0.0001 0.0021 0.0005
Punctate Nuclear 0.0075 0.0009 0.0002 0.0002 0.0024 0 0.0017 0 0.0006 0.0002 0.0001 0 0.0033 0.0001 0.0006 0.001 0.0193 0.0004
Vacuole 0.0161 0.0013 0.0051 0.0012 0.004 0.0005 0.0033 0.0002 0.0012 0.003 0.0007 0.0003 0.011 0.0008 0.0038 0.0106 0.0037 0.0047
Vacuole Periphery 0.0059 0.0002 0.0006 0.0005 0.0014 0.0002 0.0021 0 0.001 0.0005 0.0002 0.0001 0.0029 0.0002 0.0012 0.005 0.0013 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 205.9688 172.9446 141.5072 183.657 166.4279 184.5341 202.2905 199.021 189.9722 157.6848
Translational Efficiency 1.4756 1.8211 1.6526 1.4663 1.7175 2.045 1.6212 1.4797 1.5938 1.4678

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2222 1204 1570 1154 454 921 122 187 2676 2125 1692 1341

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1471.05 1567.86 2812.41 2920.24 1871.13 1676.75 3783.85 3404.32 1538.93 1615.05 2882.45 2987.74
Standard Deviation 254.10 388.25 643.10 831.40 414.66 306.38 823.08 762.86 324.55 359.17 704.09 839.11
Intensity Change Log 2 — 0.091950 0.934961 0.989241 — -0.158242 1.015945 0.863457 — -0.042744 0.980859 0.920176

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000046 0.000226 0.000210 0.001519 0.000197 0.000306 0.000449 0.000925 0.000072 0.000260 0.000227 0.001437
Bud Neck 0.000216 0.000532 0.002703 0.001910 0.000487 0.000332 0.009853 0.004426 0.000262 0.000445 0.003219 0.002261
Bud Site 0.005659 0.009059 0.007092 0.016193 0.007599 0.009960 0.006565 0.020836 0.005988 0.009449 0.007054 0.016840
Cell Periphery 0.000176 0.000387 0.002545 0.010888 0.000874 0.000338 0.009824 0.016601 0.000295 0.000366 0.003070 0.011685
Cytoplasm 0.956924 0.929030 0.836478 0.808606 0.913218 0.925262 0.552640 0.684386 0.949509 0.927397 0.816013 0.791284
Cytoplasmic Foci 0.015827 0.015556 0.012779 0.006759 0.018107 0.028807 0.034160 0.015218 0.016214 0.021299 0.014321 0.007939
Eisosomes 0.000001 0.000002 0.000002 0.000008 0.000001 0.000002 0.000008 0.000010 0.000001 0.000002 0.000002 0.000008
Endoplasmic Reticulum 0.000257 0.000656 0.000280 0.000299 0.000630 0.000806 0.000217 0.000130 0.000321 0.000721 0.000275 0.000276
Endosome 0.000642 0.001931 0.001558 0.002104 0.002014 0.002411 0.003531 0.001392 0.000875 0.002139 0.001701 0.002005
Golgi 0.003501 0.005934 0.010368 0.007792 0.018966 0.008320 0.034127 0.005375 0.006125 0.006968 0.012081 0.007455
Lipid Particles 0.000505 0.002531 0.005806 0.019786 0.001889 0.001621 0.030418 0.030825 0.000740 0.002137 0.007581 0.021326
Mitochondria 0.000102 0.000100 0.000112 0.000936 0.000029 0.000173 0.000102 0.000036 0.000090 0.000132 0.000111 0.000811
Mitotic Spindle 0.000488 0.001507 0.003429 0.002390 0.001277 0.002077 0.006129 0.002916 0.000622 0.001754 0.003624 0.002463
None 0.002515 0.002102 0.001438 0.004055 0.001409 0.000865 0.000955 0.000772 0.002328 0.001566 0.001403 0.003597
Nuclear Periphery 0.000056 0.000039 0.000341 0.000120 0.000055 0.000021 0.001488 0.000172 0.000056 0.000031 0.000424 0.000128
Nuclear Periphery Foci 0.000571 0.003678 0.005609 0.004351 0.005887 0.001222 0.021823 0.004274 0.001473 0.002614 0.006778 0.004340
Nucleolus 0.000049 0.000356 0.000101 0.000230 0.000028 0.000027 0.000138 0.000167 0.000045 0.000213 0.000104 0.000221
Nucleus 0.004714 0.008474 0.027406 0.015191 0.005929 0.005037 0.034411 0.016673 0.004920 0.006984 0.027912 0.015398
Peroxisomes 0.000117 0.000208 0.000044 0.000397 0.000030 0.000165 0.000060 0.000276 0.000102 0.000189 0.000045 0.000380
Vacuole 0.005607 0.015816 0.074833 0.093482 0.011677 0.009070 0.243067 0.192110 0.006637 0.012892 0.086964 0.107235
Vacuole Periphery 0.002025 0.001875 0.006864 0.002982 0.009695 0.003178 0.010036 0.002480 0.003326 0.002440 0.007093 0.002912

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.31 -10.80 -2.17 -1.87 -1.80 -1.71 -4.75 -1.73 -1.38 -0.80 -6.32 -10.61 -2.30 -1.94 -1.88
Bud Neck -4.18 -11.80 -11.43 -9.02 4.49 1.98 -8.37 -7.15 -7.31 2.89 -3.86 -13.59 -13.02 -11.89 4.09
Bud Site -3.88 -4.04 -6.06 -3.62 -3.80 -1.43 0.27 -3.23 -2.66 -3.50 -4.82 -3.66 -6.72 -4.21 -4.51
Cell Periphery -4.14 -8.08 -10.73 -10.49 -7.70 3.64 -6.13 -4.19 -4.40 -1.06 -1.40 -9.28 -11.48 -11.39 -7.88
Cytoplasm 7.17 23.95 21.72 16.38 0.94 -1.34 13.76 12.32 13.13 -2.86 6.60 25.24 24.07 20.10 1.31
Cytoplasmic Foci -0.01 0.19 6.66 6.48 6.62 -4.08 -4.34 -0.31 2.05 3.10 -3.97 -0.81 5.72 8.68 6.26
Eisosomes -2.96 -10.08 -7.79 -6.04 -5.59 -3.45 -7.13 -2.95 -2.54 -0.06 -4.56 -11.89 -8.26 -6.65 -5.44
Endoplasmic Reticulum -2.98 -0.93 -0.06 2.76 0.57 -0.59 4.03 4.66 2.53 1.87 -2.80 0.64 1.31 3.24 0.88
Endosome -4.39 -7.88 -2.89 0.26 0.26 -0.66 -2.28 1.18 1.62 3.14 -4.55 -7.14 -2.47 0.89 0.74
Golgi -3.46 -10.20 -2.99 -0.79 2.80 3.68 -1.81 5.14 2.19 5.94 -0.95 -6.72 -0.41 0.30 4.39
Lipid Particles -5.09 -13.37 -12.41 -10.80 -8.13 0.65 -6.75 -7.51 -7.57 0.68 -5.61 -13.94 -14.17 -13.01 -8.19
Mitochondria 0.06 -2.17 -1.91 -1.91 -1.82 -2.00 -2.71 -2.07 1.74 2.00 -1.03 -3.26 -1.93 -1.78 -1.79
Mitotic Spindle -2.04 -7.42 -2.04 -0.50 2.80 -1.41 -1.55 -1.81 -1.61 -0.10 -2.89 -6.99 -2.70 -1.28 1.72
None 1.06 4.21 -0.92 -1.29 -1.93 1.63 1.74 1.73 0.44 0.01 2.74 4.21 -0.87 -1.69 -1.88
Nuclear Periphery 0.34 -6.28 -1.44 -5.85 7.63 3.21 -5.84 -6.47 -7.72 4.99 0.61 -8.15 -2.18 -8.89 8.72
Nuclear Periphery Foci -8.36 -12.43 -9.38 -1.44 3.00 5.79 -5.48 0.80 -5.36 5.87 -4.34 -11.89 -7.80 -4.53 4.63
Nucleolus -1.44 -9.88 -2.75 0.66 -1.43 0.21 -6.54 -5.94 -5.98 -1.68 -1.39 -11.30 -3.26 0.02 -1.62
Nucleus -4.87 -18.37 -14.31 -8.16 8.54 0.79 -8.22 -6.05 -6.32 2.58 -4.28 -19.47 -15.38 -11.78 8.59
Peroxisomes -1.13 4.76 -1.38 -0.71 -1.79 -6.41 -3.61 -3.68 -1.17 -2.90 -1.84 4.20 -1.60 -0.91 -1.96
Vacuole -6.15 -18.97 -21.31 -18.00 -2.25 1.17 -12.09 -11.57 -11.71 1.12 -5.71 -21.16 -23.29 -21.58 -2.98
Vacuole Periphery 0.38 -6.65 -1.34 -1.42 5.23 2.62 0.70 3.06 1.01 4.00 1.54 -4.38 1.36 -0.28 5.87
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description UDP-glucose pyrophosphorylase (UGPase); catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p; involved in PKA-mediated oxidative stress resistance and long-term survival in stationary phase; UGP1 has a paralog, YHL012W, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-7

Ugp1

Ugp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ugp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available