ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.07 0.11 0.05 0.07 – 0.12 0.08 0.09 0.08 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.13 0.25 0.17 0.15 0.13 0.1 – 0.06 0.06 0.05 0.08 0.07 0.11 0.1 0.11 0.18 0.16 0.17 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.36 0.23 0.16 0.12 0.44 0.2 – 0.21 0.08 0 0.05 0.06 0.41 0.33 0.4 0.37 0.45 0.37 0.37 0.35 0.4 0.31 0.25 0.25
Golgi 0.05 0.12 0 0 0.05 0 – 0 0 0 0 0 0.22 0.42 0.3 0.05 0 0 0.31 0.29 0.19 0.43 0.47 0.52
Mitochondria 0.47 0.33 0.66 0.66 0.31 0.7 – 0.64 0.77 0.8 0.82 0.7 0.36 0.26 0.24 0.07 0.11 0.08 0.09 0.14 0.14 0.1 0.1 0.08
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0.05 0.05 0.05 0.06 – 0.12 0.08 0.05 0 0.11 0.08 0 0 0 0 0 0 0 0.06 0.06 0.05 0
SpindlePole 0.05 0 0.1 0 0.07 0.05 – 0.09 0.07 0.06 0 0.07 0 0.07 0.08 0.1 0.1 0.13 0 0 0 0 0 0
Vac/Vac Membrane 0.2 0.2 0.08 0 0 0 – 0 0 0.05 0 0 0 0 0.06 0.53 0.37 0.51 0.15 0.15 0.18 0.05 0.05 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 9 7 3 6 6 5 – 15 1 8 9 7 7 1 2 5 11 6 10 9 2 5 6 10
Bud 13 1 20 20 11 25 – 65 20 31 22 35 2 1 2 3 9 0 1 0 0 1 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 1 0 0 0 – 8 3 2 6 8 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 1 0 0 1 0 – 1 1 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 92 54 49 29 30 38 – 32 16 16 20 28 27 10 18 51 39 26 8 1 1 0 0 3
Endoplasmic Reticulum 6 8 1 6 5 6 – 2 2 1 2 5 12 3 3 8 5 7 3 1 2 2 3 4
Endosome 251 50 47 22 99 74 – 113 20 13 12 24 97 33 64 103 110 58 292 104 126 82 51 72
Golgi 38 26 2 8 11 8 – 9 0 8 8 12 53 42 48 15 11 4 248 84 58 115 98 148
Mitochondria 331 71 188 126 71 260 – 344 194 265 215 269 86 26 38 19 28 13 74 40 43 27 20 21
Nucleus 1 0 0 0 0 0 – 1 0 3 1 1 0 0 0 1 3 1 0 0 0 0 1 0
Nuclear Periphery 0 1 0 2 0 0 – 0 1 1 1 3 1 2 0 0 0 0 1 0 0 0 0 0
Nucleolus 2 1 1 2 1 8 – 24 9 13 7 11 2 1 1 3 4 0 0 0 0 0 0 0
Peroxisomes 27 0 14 10 11 23 – 63 21 17 11 42 19 2 7 7 2 1 20 3 17 15 9 5
SpindlePole 32 6 29 6 15 17 – 46 18 19 11 27 10 7 13 29 25 21 5 2 1 0 1 0
Vac/Vac Membrane 139 42 24 3 9 12 – 15 5 15 11 16 8 2 9 149 92 80 122 44 55 13 11 15
Unique Cell Count 700 215 286 190 226 372 534 251 331 262 382 239 101 161 279 247 157 792 297 314 268 209 285
Labelled Cell Count 943 268 379 240 270 476 738 311 412 336 490 325 130 205 393 339 217 792 297 314 268 209 285


Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.1 6.9 4.8 5.8 6.2 5.5 – 5.7 5.8 5.9 6.3 6.2 6.6 6.9 6.7 9.3 9.0 8.4 7.2 7.6 7.4
Std Deviation (1e-4) 1.0 1.2 1.1 1.3 1.5 1.2 – 1.1 1.5 1.3 1.3 1.4 1.1 1.1 1.1 1.7 1.7 1.6 1.5 1.5 1.4
Intensity Change (Log2) – – – 0.26 0.35 0.18 – 0.23 0.25 0.29 0.38 0.36 0.45 0.51 0.47 0.95 0.9 0.79 0.56 0.65 0.6

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 1.6 0 1.3 1.9 0 0 0 0 0 2.5 0
Bud 1.4 -1.0 -0.1 – 2.3 0.4 1.1 0.6 1.0 -3.5 -2.3 -2.7 -3.6 -1.7 -3.4
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 -1.2 -2.6 – -5.1 -3.8 -5.0 -3.3 -3.9 -1.9 -1.7 -1.7 0.4 -0.4 -0.2
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 3.4 0 0 0 0 0
Endosome -1.5 6.8 1.1 – 1.6 -3.0 -5.2 -4.5 -4.2 6.2 3.5 5.5 5.5 7.1 4.9
Golgi 0 3.0 0 – 0 0 0 0 2.2 8.0 11.1 9.4 3.3 2.8 0
Mitochondria 0.1 -7.7 1.1 – -0.4 2.9 4.0 4.3 1.3 -6.8 -6.9 -8.6 -14.5 -12.8 -11.6
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 3.3 0 3.0 0 2.4 0 0 0 0 0 0
Peroxisomes 0.2 0 0.7 – 3.2 1.6 0.1 -0.4 2.8 1.4 0 -0.3 -1.5 -2.8 -2.4
SpindlePole -2.9 -1.4 -2.8 – -0.7 -1.2 -2.0 -2.7 -1.4 -2.6 -1.0 -0.7 0.1 0 1.0
Vacuole -3.1 -2.0 -2.9 – -3.6 -3.3 -2.0 -2.0 -2.3 -2.4 -2.2 -1.1 11.6 8.1 10.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.2228 6.6264 6.286 5.0717 4.8048 5.9532 3.832 4.975 4.7096 4.3301 4.07 4.6613 6.6933 7.1031 7.058 6.5132 6.2014 6.8721
Actin 0.0633 0.0242 0.0148 0.0009 0.0082 0.0019 0.0215 0.0085 0.037 0.0029 0.0423 0.012 0.0183 0.0117 0.0107 0.0144 0.0026 0.0186
Bud 0.0006 0.0002 0.002 0 0.0003 0 0.0002 0.0001 0.0002 0.0003 0.0002 0.0001 0.0004 0.0001 0.0003 0.0003 0 0.0007
Bud Neck 0.0013 0.0002 0.0005 0.0002 0.0002 0.0002 0.0003 0.0002 0.0054 0.0003 0.0003 0.0004 0.0009 0.0002 0.0003 0.0005 0.0003 0.0003
Bud Periphery 0.0007 0.0002 0.0026 0 0.0006 0 0.0002 0.0001 0.0002 0.0004 0.0003 0.0001 0.0003 0 0.0003 0.0003 0 0.0004
Bud Site 0.0021 0.0005 0.0063 0.0002 0.0016 0.0001 0.0005 0.0002 0.0051 0.0005 0.0016 0.0002 0.002 0.0005 0.0006 0.002 0.0001 0.0003
Cell Periphery 0.0002 0 0.0002 0 0 0 0.0001 0 0.0001 0.0002 0 0 0.0001 0 0 0.0002 0 0
Cytoplasm 0.0025 0.0012 0.0063 0.0006 0.0006 0.0006 0.0052 0.0014 0.001 0.0017 0.0007 0.0013 0.0013 0.0021 0.002 0.0008 0.001 0.0011
Cytoplasmic Foci 0.0934 0.109 0.0803 0.181 0.076 0.0584 0.142 0.1866 0.1277 0.1268 0.1053 0.1257 0.1284 0.1682 0.1277 0.1262 0.1281 0.115
Eisosomes 0.0004 0.0001 0.0002 0 0.0001 0 0.0001 0 0.0001 0.0002 0.0002 0 0.0001 0 0.0001 0.0001 0 0
Endoplasmic Reticulum 0.0032 0.0004 0.0022 0.0001 0.0005 0.0006 0.0023 0.0002 0.0002 0.0007 0.0002 0.0008 0.0008 0.0002 0.0005 0.0002 0.0023 0.0003
Endosome 0.1554 0.2013 0.1519 0.259 0.2701 0.1416 0.2018 0.1843 0.1704 0.3553 0.3021 0.157 0.2288 0.2179 0.1932 0.2117 0.24 0.1699
Golgi 0.5502 0.6136 0.6826 0.4265 0.4899 0.7641 0.5082 0.5474 0.601 0.4343 0.5216 0.6086 0.5074 0.5579 0.6017 0.6005 0.5236 0.6247
Lipid Particles 0.0681 0.0191 0.0103 0.0273 0.0375 0.018 0.0325 0.0261 0.0082 0.0117 0.015 0.0185 0.0412 0.0181 0.0201 0.0154 0.045 0.0166
Mitochondria 0.0191 0.0091 0.016 0.0042 0.007 0.0043 0.0094 0.0042 0.0038 0.0379 0.0034 0.0074 0.0168 0.0016 0.0077 0.0046 0.003 0.0072
None 0.0011 0.0001 0.0039 0.0001 0.0007 0 0.0033 0 0.0001 0.0004 0 0.0004 0.0003 0.0003 0.0013 0 0.0006 0.0001
Nuclear Periphery 0.0042 0.0002 0.0018 0 0.002 0.0001 0.006 0.0001 0.0001 0.0024 0.0001 0.0016 0.0016 0.0001 0.0008 0.0001 0.0314 0.0001
Nucleolus 0.0002 0 0.0002 0.0001 0.0004 0 0.0025 0 0.0002 0.0025 0 0.0001 0.0001 0 0.0001 0 0.0004 0
Nucleus 0.0014 0 0.0006 0 0.0004 0 0.0024 0 0.0001 0.0036 0 0.0002 0.0003 0 0.0003 0 0.0053 0
Peroxisomes 0.0263 0.0157 0.0142 0.0972 0.0208 0.0072 0.0509 0.0394 0.0375 0.0076 0.0039 0.0624 0.0474 0.0184 0.0287 0.0211 0.0092 0.0425
Punctate Nuclear 0.0025 0.0002 0.0007 0.0012 0.0745 0.0001 0.0065 0.0002 0.0004 0.0005 0.0001 0.0018 0.001 0.0004 0.0014 0.0001 0.0014 0.0002
Vacuole 0.0019 0.0023 0.0011 0.0005 0.0024 0.0007 0.0021 0.0005 0.0005 0.0042 0.001 0.0006 0.0011 0.0013 0.0009 0.0007 0.002 0.0006
Vacuole Periphery 0.0019 0.0023 0.0012 0.001 0.0062 0.002 0.0018 0.0006 0.0006 0.0056 0.0014 0.0009 0.0013 0.0009 0.0014 0.0009 0.0036 0.0012

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 33.9341 25.4422 24.6882 47.5003 42.5777 45.9497 30.177 27.3792 37.6464 51.7952
Translational Efficiency 3.0591 3.1285 3.0369 1.98 2.2755 2.2887 2.6896 3.2057 2.4386 1.9964

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1193 1715 1516 185 2141 1556 2126 706 3334 3271 3642 891

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 715.46 883.40 1016.63 942.12 827.65 872.85 882.89 848.17 787.51 878.38 938.56 867.68
Standard Deviation 84.32 127.97 132.33 115.52 421.18 122.35 117.02 126.85 345.48 125.44 140.10 130.28
Intensity Change Log 2 — 0.304196 0.506852 0.397040 — 0.076713 0.093213 0.035333 — 0.186657 0.299794 0.214352

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001500 0.005832 0.010260 0.034189 0.005677 0.002575 0.021137 0.000670 0.004183 0.004283 0.016609 0.007630
Bud Neck 0.000136 0.000155 0.000345 0.006668 0.000046 0.000143 0.001295 0.011890 0.000078 0.000149 0.000899 0.010806
Bud Site 0.000245 0.001200 0.003454 0.040712 0.000205 0.000398 0.008335 0.032111 0.000220 0.000818 0.006303 0.033897
Cell Periphery 0.000023 0.000042 0.000035 0.000113 0.000025 0.000020 0.000043 0.000244 0.000024 0.000032 0.000040 0.000217
Cytoplasm 0.000866 0.001547 0.001405 0.091270 0.001411 0.000506 0.008968 0.087294 0.001216 0.001052 0.005820 0.088119
Cytoplasmic Foci 0.299486 0.292630 0.442595 0.277188 0.283204 0.274948 0.327127 0.173296 0.289030 0.284219 0.375191 0.194867
Eisosomes 0.000058 0.000049 0.000041 0.000106 0.000051 0.000033 0.000078 0.000048 0.000053 0.000042 0.000063 0.000060
Endoplasmic Reticulum 0.000080 0.000113 0.000805 0.001848 0.000092 0.000064 0.000622 0.001760 0.000088 0.000090 0.000698 0.001779
Endosome 0.145958 0.247643 0.201191 0.105525 0.247876 0.258293 0.308928 0.249367 0.211407 0.252709 0.264082 0.219500
Golgi 0.455538 0.407743 0.270158 0.021064 0.416616 0.428888 0.195362 0.013843 0.430544 0.417802 0.226496 0.015342
Lipid Particles 0.031263 0.009617 0.012314 0.016078 0.019490 0.009792 0.025696 0.020795 0.023703 0.009700 0.020126 0.019815
Mitochondria 0.009114 0.006968 0.000719 0.002859 0.003926 0.006043 0.005755 0.006138 0.005782 0.006528 0.003659 0.005457
Mitotic Spindle 0.001582 0.001995 0.031880 0.070261 0.000319 0.000819 0.040260 0.080715 0.000771 0.001435 0.036772 0.078544
None 0.000068 0.000016 0.000007 0.001087 0.000240 0.000008 0.000024 0.001734 0.000178 0.000012 0.000017 0.001599
Nuclear Periphery 0.000010 0.000015 0.000102 0.000273 0.000019 0.000014 0.000325 0.001640 0.000016 0.000014 0.000232 0.001356
Nuclear Periphery Foci 0.000502 0.000153 0.001864 0.002945 0.000094 0.000055 0.002213 0.005811 0.000240 0.000107 0.002068 0.005216
Nucleolus 0.000121 0.000037 0.000009 0.000213 0.000007 0.000125 0.000143 0.004056 0.000047 0.000079 0.000088 0.003259
Nucleus 0.000033 0.000045 0.000026 0.006881 0.001214 0.000506 0.000599 0.016490 0.000791 0.000264 0.000361 0.014495
Peroxisomes 0.052473 0.019478 0.010227 0.122236 0.017961 0.012128 0.025111 0.022748 0.030310 0.015982 0.018915 0.043405
Vacuole 0.000489 0.003096 0.010792 0.191941 0.000699 0.002467 0.025368 0.259739 0.000624 0.002797 0.019301 0.245662
Vacuole Periphery 0.000455 0.001624 0.001771 0.006542 0.000829 0.002175 0.002610 0.009611 0.000695 0.001886 0.002261 0.008974

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.69 -6.61 -2.87 -2.17 -1.42 2.95 -6.87 5.30 4.03 10.03 -0.14 -8.60 -0.26 -0.19 6.48
Bud Neck -0.58 -4.61 -4.78 -4.77 -4.64 -2.07 -11.15 -8.21 -8.14 -7.08 -2.44 -11.94 -9.24 -9.17 -8.35
Bud Site -2.81 -8.73 -5.39 -5.24 -4.87 -1.94 -10.62 -7.74 -7.69 -5.12 -3.22 -12.83 -9.34 -9.13 -7.14
Cell Periphery -2.27 -4.03 -6.61 -4.51 -5.67 0.82 -2.73 -1.39 -1.45 -1.21 -1.12 -3.51 -1.61 -1.53 -1.42
Cytoplasm -1.20 -2.20 -8.78 -8.73 -8.74 1.58 -8.29 -15.40 -15.58 -13.76 0.32 -8.29 -17.75 -17.79 -16.67
Cytoplasmic Foci 1.05 -20.23 7.22 6.84 16.38 1.47 -6.85 18.07 16.14 22.33 1.14 -18.42 19.82 18.87 31.32
Eisosomes 1.09 2.32 -3.20 -4.31 -5.30 3.50 -3.89 0.50 -4.14 4.90 2.66 -1.94 -0.99 -4.23 1.13
Endoplasmic Reticulum -1.98 -8.32 -4.83 -4.75 -3.01 0.92 -8.14 -8.22 -8.44 -4.75 -0.15 -11.49 -9.56 -9.59 -5.50
Endosome -17.08 -10.03 9.23 20.13 15.57 -1.73 -8.91 6.15 6.94 11.34 -9.49 -11.00 6.14 11.24 12.11
Golgi 5.77 22.56 63.26 69.70 45.59 -1.81 37.61 90.73 77.43 40.62 2.47 42.30 110.47 106.53 60.79
Lipid Particles 7.32 6.39 5.80 -0.74 0.51 4.30 -2.70 0.92 -2.84 3.41 7.98 1.67 3.45 -3.12 2.34
Mitochondria 1.27 5.96 4.66 4.29 -0.93 -1.97 -1.86 -0.25 1.07 0.91 -0.82 2.74 1.62 2.19 -0.06
Mitotic Spindle -0.75 -10.35 -4.28 -4.23 -1.47 -1.71 -14.91 -10.07 -10.00 -4.04 -2.05 -18.17 -10.89 -10.78 -4.71
None 1.23 1.46 -2.21 -2.31 -2.32 1.38 1.24 -2.03 -2.48 -2.44 1.52 1.44 -2.56 -2.95 -2.93
Nuclear Periphery -1.08 -7.06 -7.10 -7.03 -6.03 0.59 -5.75 -7.38 -7.41 -5.57 0.19 -6.64 -8.04 -8.05 -6.53
Nuclear Periphery Foci 0.84 -2.03 -3.66 -4.51 -2.23 0.60 -6.19 -7.82 -7.90 -4.04 0.85 -5.69 -8.31 -8.85 -4.73
Nucleolus 0.96 1.32 -2.33 -3.77 -4.11 -1.06 -2.50 -4.75 -4.54 -4.46 -0.47 -1.29 -4.82 -4.75 -4.69
Nucleus -0.53 0.14 -6.93 -6.93 -6.93 0.91 -0.16 -7.87 -8.33 -8.05 1.15 0.01 -9.60 -10.06 -9.79
Peroxisomes 8.62 11.80 -1.62 -4.56 -5.40 3.19 -3.36 -0.47 -3.11 2.46 7.60 5.91 0.11 -4.55 -3.53
Vacuole -4.36 -10.65 -15.37 -15.26 -14.92 -4.62 -15.05 -28.50 -28.34 -25.36 -5.92 -17.51 -32.36 -32.13 -29.94
Vacuole Periphery -5.70 -4.17 -1.06 -0.62 -0.56 -3.15 -5.28 -4.32 -3.23 -3.00 -4.81 -6.43 -4.39 -3.36 -3.07
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi
Localization
Cell Percentages Golgi (79%)
Cell Cycle Regulation No
Subcompartmental Group N/A

YKL063C

YKL063C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ykl063c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available