ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; proposed to be involved in resistance to streptozotocin and camptothecin
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.05 0 0 0 0 0 0 0
Cytoplasm 0.97 0.99 0.98 0.97 0.92 0.8 0.6 0.68 0.59 0.53 0.49 0.41 0.99 0.99 0.99 0.97 0.96 0.96 0.92 0.85 0.83 0.94 0.94 0.87
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.06 0 0 0.29 0.12 0.47 0.64 0.53 0.55 0.71 0.75 0.75 0 0 0 0 0 0 0 0 0.08 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 2 0 1 0 0 0 1 0 0 0 0 0 0 1 0 0 1 0 1 0 0 3
Bud 3 1 1 0 0 1 7 5 4 11 4 5 0 1 0 1 0 0 0 0 0 0 1 10
Bud Neck 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 4 4 3 0 1 3 3 6 5 4 2 1 5 13 17 26 20 11 0 0 0 0 0 0
Cytoplasm 377 170 179 60 117 99 131 170 158 142 75 81 425 579 566 270 351 241 368 158 162 264 483 470
Endoplasmic Reticulum 3 0 1 0 2 0 2 1 4 3 1 7 5 2 3 8 16 5 5 5 10 1 3 8
Endosome 0 0 0 0 3 0 1 1 0 2 0 1 0 1 0 1 0 3 6 3 1 0 4 5
Golgi 0 0 1 0 0 0 0 0 0 0 0 0 1 3 1 0 0 0 1 1 1 0 0 1
Mitochondria 22 6 3 18 15 58 140 134 145 190 115 147 0 0 0 4 7 1 8 4 14 4 7 18
Nucleus 1 0 1 0 0 0 0 0 0 0 1 1 1 2 0 0 0 2 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 0 1 1 0 0 0 0 4 0 0 0 0 1 0 0 1 0 0 0 3
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 2 1 0 0 0 1 0 0 0 0 1 0 0 0 0 2
Vac/Vac Membrane 0 0 1 0 1 2 2 5 4 5 3 5 0 0 4 3 9 5 2 5 1 3 4 9
Unique Cell Count 389 172 183 62 127 124 219 251 266 266 153 197 431 584 572 279 367 250 403 186 195 281 515 543
Labelled Cell Count 410 181 192 78 140 164 288 322 323 358 201 252 437 602 592 314 404 268 403 186 195 281 515 543


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.4 7.2 6.2 5.9 5.2 4.4 4.3 4.2 4.0 4.1 3.7 3.9 7.7 7.7 7.4 8.4 8.0 7.5 7.8 8.1 8.2
Std Deviation (1e-4) 0.5 0.9 0.7 2.0 0.7 0.9 1.4 0.9 0.9 1.2 0.9 1.1 1.0 1.1 1.0 1.2 1.3 1.0 1.2 1.4 1.5
Intensity Change (Log2) – – – -0.06 -0.25 -0.47 -0.51 -0.56 -0.61 -0.6 -0.72 -0.66 0.33 0.33 0.26 0.44 0.38 0.28 0.35 0.39 0.42


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 3.3 2.1 1.6
Cytoplasm -0.5 -2.4 -5.3 -9.0 -7.8 -9.2 -10.2 -10.4 -11.9 0.7 1.5 1.2 -0.7 -1.3 -0.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 2.4 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 6.7 3.8 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.7591 3.5441 2.5056 2.4517 2.2233 2.7032 2.2032 2.6585 2.23 2.0252 2.1566 2.3437 2.5439 2.7734 2.625 2.7883 2.4363 2.5209
Actin 0.0055 0.0013 0.0073 0.0429 0.0087 0.0019 0.03 0.0036 0.0127 0.0613 0.0149 0.0063 0.0394 0.0012 0.022 0.0213 0.0305 0.0149
Bud 0.0009 0.0002 0.0008 0.0018 0.0001 0.0001 0.0017 0.0017 0.0032 0.0015 0.0042 0.0004 0.0048 0.0091 0.0111 0.0008 0.0003 0.005
Bud Neck 0.0035 0.0001 0.0004 0.0007 0.0003 0.0005 0.0068 0.0002 0.0005 0.0008 0.0006 0.0016 0.0128 0.0003 0.0046 0.0025 0.0004 0.0025
Bud Periphery 0.0011 0.0001 0.0005 0.0019 0 0.0001 0.0086 0.0008 0.004 0.0011 0.0072 0.0005 0.0046 0.0029 0.0055 0.0011 0.0003 0.0056
Bud Site 0.0018 0.0006 0.0015 0.0117 0.0004 0.0002 0.0042 0.0104 0.0035 0.0162 0.0033 0.0005 0.0272 0.0062 0.0136 0.0013 0.0009 0.0015
Cell Periphery 0.0002 0.0002 0.0002 0.0003 0.0001 0.0001 0.0005 0.0001 0.0002 0.0002 0.0003 0.0001 0.0013 0.0005 0.0013 0.0002 0 0.0002
Cytoplasm 0.682 0.8744 0.7548 0.804 0.7905 0.8824 0.6087 0.8795 0.8061 0.8001 0.6715 0.8696 0.5762 0.8649 0.8066 0.769 0.7864 0.8316
Cytoplasmic Foci 0.0286 0.0077 0.0292 0.0224 0.0351 0.0125 0.0528 0.0108 0.0249 0.021 0.0463 0.0182 0.0609 0.0203 0.0121 0.0286 0.0323 0.0356
Eisosomes 0.0002 0 0.0001 0.0001 0 0 0.0003 0 0.0003 0.0004 0.0002 0 0.0005 0 0.0003 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0222 0.0056 0.0048 0.0043 0.0051 0.0043 0.0139 0.0041 0.0051 0.0087 0.0071 0.0041 0.0148 0.0031 0.0057 0.0101 0.002 0.0025
Endosome 0.0291 0.007 0.0195 0.0516 0.0143 0.0143 0.0767 0.0083 0.0315 0.0276 0.0778 0.0326 0.0463 0.0184 0.0168 0.0485 0.0378 0.0222
Golgi 0.0084 0.0021 0.0107 0.0045 0.0019 0.0021 0.0213 0.0009 0.0081 0.0072 0.024 0.0069 0.0223 0.0041 0.0047 0.0116 0.0224 0.0123
Lipid Particles 0.0045 0.0002 0.0031 0.0016 0.0037 0.0033 0.0157 0.0001 0.002 0.0071 0.0098 0.0042 0.0088 0.0003 0.0012 0.0044 0.0061 0.0029
Mitochondria 0.0067 0.0008 0.0129 0.0023 0.0002 0.0022 0.0168 0.0004 0.0175 0.0043 0.054 0.0013 0.0099 0.0008 0.008 0.0176 0.0054 0.0044
None 0.192 0.0961 0.1376 0.0359 0.0784 0.0679 0.089 0.075 0.0636 0.0263 0.0241 0.0448 0.127 0.0604 0.0789 0.0509 0.0476 0.0423
Nuclear Periphery 0.0033 0.0008 0.001 0.0011 0.0015 0.0004 0.021 0.0007 0.0017 0.001 0.0264 0.0009 0.0056 0.0007 0.0008 0.0054 0.0012 0.0003
Nucleolus 0.0003 0 0.0002 0.0001 0.0005 0 0.0008 0 0.0004 0.0001 0.0006 0.0001 0.0008 0.0001 0.0002 0.0002 0.0001 0.0001
Nucleus 0.0012 0.0005 0.0009 0.0009 0.0013 0.0005 0.0063 0.0009 0.0021 0.001 0.0043 0.0011 0.0027 0.0014 0.002 0.002 0.0008 0.001
Peroxisomes 0.0025 0.0001 0.0083 0.0015 0.0087 0.0048 0.01 0.0003 0.0026 0.0086 0.0064 0.0007 0.0203 0.0023 0.0015 0.0023 0.0207 0.0122
Punctate Nuclear 0.0016 0.0002 0.0026 0.0006 0.0469 0.0004 0.0059 0.0004 0.004 0.0005 0.0023 0.0006 0.0053 0.0005 0.0007 0.0016 0.0016 0.0008
Vacuole 0.0036 0.0015 0.0028 0.0078 0.0017 0.0015 0.0057 0.0015 0.0047 0.0039 0.0086 0.0044 0.0066 0.0022 0.002 0.0106 0.0022 0.0017
Vacuole Periphery 0.001 0.0002 0.0006 0.0019 0.0003 0.0005 0.0033 0.0002 0.0012 0.0013 0.0061 0.0009 0.0018 0.0004 0.0004 0.01 0.001 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 8.563 9.4774 11.9014 11.7595 16.3891 9.7809 12.8996 13.9302 14.2832 14.5247
Translational Efficiency 1.6263 1.6556 1.0918 1.6772 0.8613 1.5118 1.18 1.0818 1.0332 0.97

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1474 136 1391 1467 1460 2532 369 800 2934 2668 1760 2267

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 732.55 994.00 989.93 1037.71 686.05 857.51 1093.14 963.33 709.41 864.47 1011.57 1011.46
Standard Deviation 92.24 138.27 121.96 131.35 105.91 100.97 139.81 169.80 101.96 107.48 132.74 150.34
Intensity Change Log 2 — 0.440319 0.434399 0.502404 — 0.321840 0.672093 0.489716 — 0.384234 0.554243 0.496282

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000215 0.000700 0.000145 0.001690 0.000160 0.000235 0.000200 0.003616 0.000187 0.000259 0.000156 0.002370
Bud Neck 0.012220 0.008381 0.001705 0.004027 0.004802 0.011211 0.001890 0.006816 0.008529 0.011066 0.001744 0.005011
Bud Site 0.019419 0.036362 0.005758 0.028535 0.013340 0.021380 0.012632 0.029398 0.016394 0.022144 0.007199 0.028839
Cell Periphery 0.000311 0.000125 0.000056 0.000121 0.000437 0.000068 0.000122 0.000968 0.000374 0.000071 0.000069 0.000420
Cytoplasm 0.367762* 0.435210* 0.725461* 0.611981* 0.516068* 0.531866* 0.545763* 0.470869* 0.441561* 0.526939* 0.687786* 0.562184*
Cytoplasmic Foci 0.363141* 0.334933* 0.034532 0.063179 0.247526* 0.259338* 0.051585 0.073016 0.305610* 0.263191* 0.038108 0.066650
Eisosomes 0.000242 0.000061 0.000015 0.000023 0.000071 0.000053 0.000058 0.002591 0.000157 0.000053 0.000024 0.000929
Endoplasmic Reticulum 0.007529 0.001749 0.001588 0.002767 0.004629 0.001073 0.001613 0.001322 0.006086 0.001108 0.001593 0.002257
Endosome 0.037401 0.041445 0.005184 0.010834 0.029192 0.025247 0.006740 0.016416 0.033316 0.026073 0.005511 0.012804
Golgi 0.043066 0.005870 0.000273 0.004943 0.005716 0.014692 0.000212 0.008068 0.024480 0.014243 0.000260 0.006046
Lipid Particles 0.011342 0.002222 0.001064 0.002384 0.011346 0.002581 0.002605 0.004209 0.011344 0.002563 0.001387 0.003028
Mitochondria 0.025289 0.002906 0.000832 0.002455 0.003607 0.005246 0.000086 0.002245 0.014500 0.005127 0.000676 0.002381
Mitotic Spindle 0.001618 0.000951 0.005634 0.044175 0.000534 0.011073 0.001118 0.026938 0.001079 0.010557 0.004687 0.038092
None 0.002709 0.000286 0.002622 0.001047 0.005269 0.000689 0.005861 0.006282 0.003983 0.000668 0.003301 0.002894
Nuclear Periphery 0.000168 0.000087 0.000880 0.000726 0.000814 0.000120 0.000815 0.000830 0.000489 0.000118 0.000866 0.000763
Nuclear Periphery Foci 0.000256 0.001105 0.002547 0.004168 0.001377 0.000254 0.006277 0.002862 0.000814 0.000297 0.003329 0.003707
Nucleolus 0.000572 0.000252 0.000275 0.000429 0.001712 0.000386 0.000335 0.002289 0.001139 0.000379 0.000288 0.001085
Nucleus 0.015307 0.012551 0.099405 0.037684 0.045059 0.014818 0.110572 0.129892 0.030112 0.014702 0.101746 0.070223
Peroxisomes 0.003210 0.008714 0.000305 0.001349 0.001764 0.003722 0.000358 0.002813 0.002491 0.003976 0.000316 0.001866
Vacuole 0.069479 0.102506 0.111214 0.172771 0.100583 0.090421 0.250133* 0.203628* 0.084957 0.091037 0.140340 0.183660
Vacuole Periphery 0.018743 0.003583 0.000504 0.004714 0.005994 0.005527 0.001025 0.004931 0.012399 0.005428 0.000613 0.004790

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.43 2.31 -4.03 -1.01 -4.38 -2.51 -4.22 -2.26 -2.17 -2.09 -2.73 0.40 -3.67 -3.44 -3.70
Bud Neck 3.05 14.69 11.22 3.72 -4.00 -8.08 7.27 0.31 6.52 -3.19 -3.17 15.57 8.89 8.95 -5.06
Bud Site -2.47 9.64 0.40 2.56 -7.27 -3.98 1.53 -2.53 -0.20 -3.37 -3.66 7.78 -1.90 1.16 -8.01
Cell Periphery 4.57 7.86 6.84 1.38 -5.06 3.14 2.73 -0.06 -2.81 -2.45 4.98 5.02 2.05 -2.99 -3.04
Cytoplasm -2.77 -33.54 -14.55 -3.24 16.31 -1.83 2.46 6.68 8.46 2.51 -11.53 -24.28 -5.49 4.95 17.06
Cytoplasmic Foci 1.82 57.90 53.39 14.58 -6.46 -1.68 36.30 30.96 37.16 -5.41 7.72 66.07 58.97 46.54 -8.78
Eisosomes 9.76 15.37 14.93 3.09 -5.08 4.96 3.54 -1.85 -1.88 -1.88 13.14 17.05 -1.27 -1.79 -1.92
Endoplasmic Reticulum 4.24 5.93 5.78 0.09 -0.16 5.95 4.52 5.94 0.05 4.25 8.44 7.43 7.72 -1.39 0.88
Endosome -0.38 21.33 19.24 4.76 -2.56 2.53 17.22 9.93 9.11 -4.10 5.43 27.13 21.59 16.03 -4.67
Golgi 17.97 24.60 22.31 2.82 -2.87 -11.12 14.33 1.70 8.01 -2.88 8.86 25.25 19.65 13.16 -4.05
Lipid Particles 10.70 14.16 11.38 -1.08 -6.65 11.18 11.49 8.76 -0.81 -1.46 15.99 18.85 14.63 -1.02 -5.84
Mitochondria 9.22 15.52 15.01 0.88 -0.61 -2.05 6.27 3.21 5.26 -1.68 9.43 15.53 14.54 6.19 -1.04
Mitotic Spindle 1.16 -2.93 -10.90 -11.16 -9.67 -7.02 -2.68 -8.04 -6.00 -7.59 -6.59 -3.85 -13.62 -9.85 -12.07
None 2.55 0.29 1.33 -8.55 3.95 5.37 0.59 1.00 -2.32 0.55 5.17 1.62 2.21 -3.34 1.19
Nuclear Periphery 2.14 -12.22 -13.04 -15.36 -0.79 6.25 -2.87 -0.66 -4.29 1.05 5.83 -7.50 -5.76 -10.89 0.09
Nuclear Periphery Foci -2.58 -10.87 -13.10 -6.98 -3.98 7.93 -6.73 -6.50 -9.12 2.36 6.45 -10.90 -13.38 -15.72 -2.21
Nucleolus 1.61 1.48 0.37 -2.95 -2.73 5.33 5.91 0.36 -1.21 -1.36 4.59 5.41 0.97 -1.46 -1.81
Nucleus 0.77 -26.78 -18.82 -14.59 14.93 12.83 -11.41 -6.39 -12.77 4.99 11.19 -25.36 -13.13 -21.43 13.61
Peroxisomes -3.24 16.11 10.19 4.58 -5.85 -6.72 7.11 -0.09 4.96 -4.58 -5.77 15.84 6.15 10.40 -7.11
Vacuole -3.31 -11.90 -28.08 -12.24 -16.81 2.28 -15.23 -19.27 -20.58 0.59 -2.27 -16.24 -33.34 -32.11 -14.73
Vacuole Periphery 10.80 15.76 13.50 1.71 -3.02 0.88 10.54 3.65 3.33 -1.80 9.91 18.69 13.42 6.24 -3.39
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; proposed to be involved in resistance to streptozotocin and camptothecin
Localization
Cell Percentages cytoplasm (85%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YKL075C

YKL075C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ykl075c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available