Standard name
Human Ortholog
Description Kinesin-like myosin passenger-protein; interacts with Myo2p and enhances its interaction with Sec4p during transport of secretory vesicles; controls actin cable structure and dynamics
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.22 0.25 0.22 0.33 0.23 0.16 0.19 – 0.12 0.09 0.12 0.1 – 0.14 0.17 0.25 0.18 0.12 0.19 0.22 0.15 0.15 0.13 0.13
Bud 0.18 0.17 0.15 0.18 0.19 0.18 0.15 – 0.12 0.17 0.16 0.14 – 0.06 0.1 0.09 0.07 0.08 0.31 0.24 0.2 0.24 0.42 0.39
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0.09 0.13 0.12 0.11 0.17 0.15
Bud Site 0.14 0.08 0.07 0.06 0.06 0.11 0.09 – 0 0 0 0.05 – 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0.05 0 0 0 – 0 0.08 0.06 0.1 0.07 0 0 0 0 0 0
Cytoplasm 0.36 0.4 0.54 0.29 0.34 0.35 0.39 – 0.38 0.36 0.31 0.37 – 0.66 0.73 0.34 0.34 0.32 0.21 0.2 0.21 0.1 0.06 0.15
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 – 0.05 0 0.05 0 – 0.05 0 0 0 0 0 0 0 0 0 0
Endosome 0.09 0.09 0 0.09 0.05 0.08 0 – 0 0.06 0 0.07 – 0 0 0.08 0.09 0.17 0.06 0.05 0.08 0 0.07 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0.08 0.07 0 0 0 0 0 0 0
Mitochondria 0.19 0.05 0.05 0 0 0.14 0.13 – 0.29 0.28 0.42 0.27 – 0 0 0.11 0.06 0.08 0 0 0.11 0 0 0
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0.13 0.12 0 0.1 0.1 0.14 0.07 – 0.05 0 0 0.05 – 0.07 0 0 0.09 0.08 0 0 0 0.06 0 0
SpindlePole 0.05 0 0.07 0.2 0.22 0.19 0.11 – 0.06 0.1 0.05 0.08 – 0.07 0 0.09 0.15 0.17 0 0 0 0.13 0.07 0.06
Vac/Vac Membrane 0 0 0.07 0 0.05 0 0.07 – 0.08 0.09 0.08 0.06 – 0 0 0.16 0.1 0.13 0 0 0 0.08 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 25 32 9 56 69 38 60 – 25 25 43 46 – 15 19 54 59 35 26 35 13 3 23 35
Bud 20 22 6 31 55 43 47 – 26 48 57 60 – 6 12 20 21 24 43 38 17 5 76 102
Bud Neck 0 1 0 4 4 1 4 – 1 4 1 4 – 0 0 0 6 0 11 20 10 2 30 41
Bud Site 16 11 3 10 19 26 29 – 9 12 11 24 – 4 1 6 13 13 – – – – – –
Cell Periphery 1 4 1 7 3 2 5 – 10 7 13 11 – 2 9 12 32 20 0 0 0 0 0 0
Cytoplasm 41 52 22 49 100 84 122 – 80 103 109 164 – 71 84 74 111 96 28 33 18 2 11 39
Endoplasmic Reticulum 1 6 1 7 3 9 12 – 10 9 16 14 – 5 0 8 9 13 3 3 2 0 0 3
Endosome 10 12 1 15 14 20 14 – 9 16 14 33 – 4 1 17 28 51 8 8 6 0 13 9
Golgi 0 5 0 0 3 2 1 – 0 0 4 3 – 1 1 17 23 11 2 1 0 0 0 0
Mitochondria 22 7 2 6 8 33 41 – 61 81 145 119 – 0 0 24 20 24 4 6 9 0 4 4
Nucleus 2 1 1 1 5 3 7 – 2 5 0 3 – 0 0 1 4 6 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 1 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 1 1 1 3 4 13 – 3 11 5 6 – 0 0 0 1 5 0 0 0 0 0 0
Peroxisomes 15 15 0 17 30 33 22 – 11 10 12 21 – 7 5 8 30 23 1 1 0 1 4 5
SpindlePole 6 4 3 34 64 45 35 – 12 29 17 36 – 8 3 19 49 52 1 3 3 2 12 16
Vac/Vac Membrane 2 5 3 4 15 9 23 – 17 25 27 26 – 2 4 34 31 39 2 6 2 1 3 3
Unique Cell Count 113 130 41 168 296 242 314 209 290 348 442 107 115 217 322 299 138 162 87 21 182 266
Labelled Cell Count 161 178 53 242 395 352 435 276 385 474 571 125 139 294 437 412 138 162 87 21 182 266


Ambiguous, Bud, Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.3 8.2 7.1 7.5 7.9 7.1 7.1 – 6.5 6.8 6.3 6.6 – 8.7 8.7 10.3 10.3 10.0 – 7.4 7.6
Std Deviation (1e-4) 0.8 1.1 1.2 1.0 1.5 1.4 1.8 – 1.4 1.5 1.3 1.4 – 1.1 1.4 2.0 1.9 2.2 – 1.1 1.0
Intensity Change (Log2) – – – 0.09 0.17 0.01 0.02 – -0.12 -0.05 -0.16 -0.09 – 0.29 0.29 0.55 0.54 0.5 – 0.06 0.11

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP7000510WT3HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.4 0.2 -1.0 -0.4 – -1.7 0 -1.7 0 – -1.2 -0.8 0.4 -0.6 -1.8
Bud 0.6 0.6 0.5 0.1 – -0.4 0.3 0.3 -0.2 – 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Cytoplasm -3.0 -2.5 -2.3 -1.8 – -1.8 -2.2 -2.9 -2.1 – 1.4 2.3 -2.4 -2.4 -2.7
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 – 0 0 0 0 2.4
Golgi 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Mitochondria 0 0 1.6 0 – 3.3 3.2 4.6 3.1 – 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 – 0 0 0 0 0
SpindlePole 1.9 2.2 1.8 0 – 0 0 0 0 – 0 0 0 1.4 1.6
Vacuole 0 0 0 0 – 0 0 0 0 – 0 0 1.4 0 1.0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.5869 3.3819 2.9228 3.4572 2.3901 3.0058 3.4741 4.2539 4.1594 3.3851 3.7584 4.1336 1.299 1.9264 1.7782 1.7575 1.626 2.0494
Actin 0.2129 0.052 0.176 0.2946 0.3239 0.0361 0.1287 0.0553 0.1824 0.0651 0.2819 0.08 0.1119 0.0488 0.1775 0.1461 0.2623 0.1003
Bud 0.0267 0.0203 0.1923 0.0917 0.0454 0.0074 0.0647 0.0573 0.2424 0.15 0.1031 0.0127 0.0586 0.0642 0.2323 0.1419 0.0238 0.0098
Bud Neck 0.0387 0.0087 0.0121 0.0092 0.0447 0.5925 0.0302 0.0067 0.0015 0.0018 0.0162 0.495 0.0372 0.0091 0.0037 0.0025 0.0021 0.4935
Bud Periphery 0.0427 0.0115 0.2446 0.1448 0.092 0.0071 0.0554 0.0339 0.2972 0.3363 0.1723 0.0056 0.0804 0.0405 0.2714 0.2599 0.0388 0.011
Bud Site 0.0917 0.4289 0.0951 0.0319 0.0084 0.0122 0.1541 0.5103 0.1062 0.0135 0.0187 0.006 0.1875 0.4439 0.0642 0.0304 0.0107 0.0092
Cell Periphery 0.003 0.0016 0.0017 0.0015 0.0004 0.0007 0.0027 0.0023 0.0016 0.0014 0.0026 0.0006 0.0021 0.0014 0.0012 0.0015 0.0007 0.0007
Cytoplasm 0.1052 0.2767 0.1076 0.2381 0.1568 0.1324 0.1439 0.1965 0.0919 0.1383 0.2258 0.1494 0.1853 0.2181 0.12 0.1736 0.3169 0.1356
Cytoplasmic Foci 0.2196 0.0895 0.0473 0.0292 0.0636 0.1385 0.2201 0.0938 0.0226 0.0779 0.0474 0.1219 0.169 0.0697 0.0339 0.0362 0.0824 0.1454
Eisosomes 0.0013 0.0002 0.0002 0.0004 0.0006 0.0001 0.0005 0.0001 0.0002 0.0001 0.0003 0.0001 0.0003 0.0001 0.0002 0.0001 0.0002 0.0001
Endoplasmic Reticulum 0.0079 0.002 0.0062 0.0033 0.0011 0.0027 0.0156 0.0007 0.0019 0.003 0.0025 0.0022 0.0068 0.0078 0.0012 0.0057 0.0023 0.0019
Endosome 0.0483 0.0201 0.0421 0.0603 0.0566 0.0349 0.039 0.0053 0.0112 0.0603 0.025 0.0356 0.0567 0.0437 0.026 0.1015 0.0881 0.0248
Golgi 0.046 0.008 0.0241 0.021 0.093 0.017 0.0242 0.0054 0.0081 0.0532 0.0283 0.0366 0.0283 0.017 0.0116 0.0275 0.0307 0.02
Lipid Particles 0.018 0.0018 0.008 0.0033 0.0481 0.0011 0.0131 0.0024 0.0015 0.0307 0.0026 0.0038 0.0095 0.0011 0.0063 0.0024 0.0322 0.0101
Mitochondria 0.0198 0.0017 0.0105 0.0188 0.0205 0.0015 0.0138 0.001 0.0057 0.0187 0.028 0.0056 0.0046 0.0026 0.0068 0.0095 0.0103 0.0061
None 0.045 0.0311 0.0061 0.0043 0.0011 0.0016 0.0105 0.0015 0.0135 0.0026 0.0275 0.0014 0.0131 0.0084 0.0064 0.0064 0.0219 0.0033
Nuclear Periphery 0.0076 0.0013 0.0059 0.0022 0.0007 0.0003 0.0101 0.0002 0.0005 0.0009 0.0008 0.0018 0.0035 0.0009 0.0011 0.0052 0.0012 0.0005
Nucleolus 0.0015 0.0012 0.0004 0.0027 0.0001 0.0002 0.0013 0.0005 0.0002 0.0002 0.0008 0.0006 0.0035 0.0012 0.0018 0.0005 0.001 0.0019
Nucleus 0.0038 0.0035 0.0022 0.0026 0.0003 0.0005 0.0177 0.001 0.0005 0.0007 0.0012 0.0031 0.0025 0.0038 0.0021 0.0022 0.0012 0.0008
Peroxisomes 0.0312 0.0079 0.01 0.0067 0.036 0.0073 0.0383 0.0181 0.0075 0.0281 0.0048 0.034 0.0179 0.0078 0.02 0.006 0.0363 0.0204
Punctate Nuclear 0.0183 0.008 0.0021 0.0174 0.0016 0.0023 0.0059 0.0035 0.0006 0.0009 0.0023 0.0018 0.0077 0.0032 0.0064 0.0015 0.0275 0.0026
Vacuole 0.009 0.021 0.0041 0.0132 0.0029 0.0028 0.0085 0.0041 0.0022 0.0112 0.0061 0.0014 0.0117 0.0057 0.0044 0.0315 0.0065 0.0015
Vacuole Periphery 0.002 0.003 0.0015 0.0028 0.0021 0.0006 0.0017 0.0003 0.0007 0.005 0.0019 0.0006 0.0018 0.0011 0.0015 0.0077 0.0026 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.0361 21.0187 13.74 16.1446 15.2424 11.7497 17.71 20.3202 16.4007 16.9946
Translational Efficiency 0.7502 0.6038 0.8748 0.7025 0.6106 0.9197 0.8175 0.6639 0.744 0.7464

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
356 1574 200 1065 1775 1067 106 1974 2131 2641 306 3039

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 738.98 837.90 1087.00 1011.43 770.90 768.05 1252.85 1040.88 765.57 809.68 1144.45 1030.56
Standard Deviation 217.58 102.68 131.03 164.46 89.61 92.57 155.79 133.29 121.40 104.50 160.80 145.66
Intensity Change Log 2 — 0.181243 0.556745 0.452789 — -0.005343 0.700598 0.433188 — 0.088993 0.631982 0.442815

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.040969 0.016906 0.031821 0.062580 0.022444 0.016830 0.030560 0.045183 0.025538 0.016875 0.031384 0.051279
Bud Neck 0.056488 0.039470 0.031796 0.012884 0.068752 0.061958 0.014733 0.019093 0.066703 0.048556 0.025885 0.016917
Bud Site 0.285761 0.320251 0.526526 0.284759 0.366271 0.359306 0.262509 0.305597 0.352821 0.336030 0.435069 0.298295
Cell Periphery 0.002508 0.000443 0.000614 0.000559 0.000920 0.001067 0.000850 0.000302 0.001185 0.000695 0.000696 0.000392
Cytoplasm 0.145803 0.249225 0.143397 0.375786 0.200455 0.210395 0.310086 0.483295 0.191325 0.233537 0.201139 0.445619
Cytoplasmic Foci 0.159320 0.200386 0.063938 0.104778 0.176713 0.174011 0.157074 0.052668 0.173807 0.189730 0.096201 0.070930
Eisosomes 0.001290 0.000399 0.000169 0.000207 0.000684 0.000884 0.000148 0.000132 0.000785 0.000595 0.000162 0.000158
Endoplasmic Reticulum 0.004158 0.001292 0.001559 0.000957 0.001043 0.000648 0.003613 0.000234 0.001563 0.001032 0.002271 0.000487
Endosome 0.074815 0.042213 0.019706 0.021783 0.038687 0.047920 0.028930 0.008955 0.044723 0.044519 0.022901 0.013450
Golgi 0.070364 0.052920 0.001616 0.019332 0.047625 0.038614 0.015241 0.006879 0.051424 0.047140 0.006335 0.011243
Lipid Particles 0.010507 0.003250 0.002636 0.005172 0.002732 0.002734 0.005221 0.001519 0.004031 0.003041 0.003531 0.002799
Mitochondria 0.033572 0.010317 0.000144 0.002105 0.017320 0.013866 0.000061 0.002554 0.020035 0.011751 0.000115 0.002396
Mitotic Spindle 0.006905 0.005898 0.018179 0.017107 0.003552 0.004152 0.010707 0.010163 0.004112 0.005193 0.015591 0.012596
None 0.001691 0.000458 0.000126 0.000180 0.000454 0.000336 0.000062 0.000117 0.000661 0.000409 0.000104 0.000139
Nuclear Periphery 0.000088 0.000027 0.000095 0.000073 0.000028 0.000049 0.000136 0.000023 0.000038 0.000036 0.000109 0.000040
Nuclear Periphery Foci 0.000635 0.000546 0.002711 0.000680 0.000664 0.000855 0.015559 0.000164 0.000660 0.000671 0.007162 0.000345
Nucleolus 0.000902 0.000101 0.000100 0.000326 0.000132 0.000258 0.000113 0.000054 0.000261 0.000165 0.000104 0.000149
Nucleus 0.010083 0.002016 0.005079 0.002424 0.001609 0.001123 0.006864 0.001904 0.003025 0.001656 0.005698 0.002086
Peroxisomes 0.070659 0.031399 0.047851 0.032496 0.033807 0.046108 0.017790 0.031712 0.039963 0.037342 0.037437 0.031987
Vacuole 0.015611 0.018597 0.101701 0.053265 0.012971 0.015652 0.118986 0.028271 0.013412 0.017407 0.107689 0.037030
Vacuole Periphery 0.007870 0.003887 0.000236 0.002545 0.003137 0.003234 0.000758 0.001181 0.003928 0.003623 0.000417 0.001659

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 3.50 1.56 -1.69 -7.48 -4.03 1.98 -1.03 -5.62 -7.05 -2.22 3.68 -0.74 -6.56 -10.44 -4.24
Bud Neck 2.59 3.81 7.26 9.97 3.50 1.31 10.39 14.04 10.80 -0.97 4.82 9.83 16.11 13.96 2.19
Bud Site -1.95 -5.73 1.63 5.45 7.51 0.61 4.49 8.13 6.27 -1.45 1.85 -1.47 9.03 7.53 5.37
Cell Periphery 4.35 3.94 4.20 -1.16 0.91 -0.57 0.65 6.08 3.18 4.82 3.25 3.71 6.92 3.17 4.09
Cytoplasm -8.28 -0.73 -17.30 -12.30 -12.38 -1.10 -4.40 -32.13 -27.77 -6.88 -6.09 -1.49 -34.86 -29.34 -15.86
Cytoplasmic Foci -4.06 8.39 5.65 13.67 -4.44 0.29 1.65 22.58 18.15 7.45 -2.73 9.62 20.96 25.40 3.59
Eisosomes 3.89 5.04 4.98 3.38 -0.45 -0.76 6.34 6.63 3.08 0.88 1.45 7.77 8.04 4.22 0.84
Endoplasmic Reticulum 2.06 1.42 2.36 1.59 3.59 1.99 -3.88 4.81 3.54 5.29 1.79 -2.64 3.97 4.04 7.08
Endosome 3.99 6.02 6.90 7.72 0.06 -2.47 2.51 13.67 12.17 5.53 0.04 5.51 13.89 15.74 3.04
Golgi 2.20 9.31 7.02 11.14 -6.98 2.81 3.97 17.44 13.39 0.90 1.49 12.55 17.25 18.79 -1.34
Lipid Particles 2.53 2.45 1.63 -2.14 -1.82 -0.11 -3.15 2.76 1.86 4.31 1.62 0.01 1.41 -0.11 1.40
Mitochondria 4.64 6.77 6.39 8.57 -2.84 1.60 13.51 11.16 6.44 -5.45 5.17 14.73 12.84 10.46 -5.97
Mitotic Spindle 0.48 -1.39 -3.15 -4.21 -0.14 -0.65 -0.74 -4.57 -3.80 -0.06 -1.37 -1.94 -6.23 -5.35 0.25
None 2.30 2.82 2.81 3.70 -0.16 0.84 4.53 3.85 2.16 -3.67 2.00 4.34 4.45 4.66 -0.30
Nuclear Periphery 2.74 -2.10 0.05 -3.24 2.26 -0.76 -3.72 -0.14 0.76 3.86 0.28 -4.81 -0.99 -1.31 4.50
Nuclear Periphery Foci 0.26 -4.04 -0.96 -1.45 3.87 -0.32 -4.77 1.03 1.49 4.94 -0.05 -5.73 0.58 1.09 6.10
Nucleolus 1.48 1.44 0.94 -0.90 -0.83 -2.06 0.48 2.77 3.21 1.02 0.93 1.52 0.78 0.12 -0.47
Nucleus 2.55 0.62 2.14 -3.85 3.64 2.63 -4.80 -4.89 -7.82 3.86 2.43 -4.29 0.32 -6.04 5.15
Peroxisomes 5.26 2.91 5.49 0.76 1.94 -3.39 3.43 1.43 4.48 -2.73 0.96 1.33 4.15 3.47 0.74
Vacuole -1.11 -8.00 -12.62 -13.08 4.34 -1.64 -7.72 -12.53 -10.23 6.01 -3.16 -10.72 -18.26 -16.14 7.50
Vacuole Periphery 2.17 4.35 3.13 2.32 -3.99 -0.20 9.77 4.28 3.62 -0.79 0.61 10.00 5.17 4.38 -3.20
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Kinesin-like myosin passenger-protein; interacts with Myo2p and enhances its interaction with Sec4p during transport of secretory vesicles; controls actin cable structure and dynamics
Localization
Cell Percentages cytoplasm (21%), actin (18%), mixed (25%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Smy1

Smy1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Smy1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available