Standard name
Human Ortholog
Description Gamma subunit of translational elongation factor eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the ribosomal complex
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0.07 0.06 0.06 0.09 0.14 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.99 0.98 1.0 0.97 0.96 0.97 0.88 0.82 0.79 0.82 0.75 0.78 0.98 0.97 0.97 0.97 0.96 1.0 0.96 0.97 0.91 0.92 0.93 0.84
Endoplasmic Reticulum 0 0 0 0 0 0 0.1 0.14 0.13 0.1 0.13 0.09 0 0 0 0.06 0.07 0.09 0 0 0 0 0 0.05
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 0 0 5 2 17 11 7 12 0 0 0 0 0 0 0 0 0 0 0 1
Bud 1 4 0 0 0 0 1 1 0 0 2 2 0 0 0 0 0 0 3 3 1 1 0 1
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 4 2 1 4 6 20 19 15 26 25 26 2 1 2 4 10 4 0 0 0 0 0 0
Cytoplasm 600 472 242 192 250 243 258 247 213 249 133 215 251 290 328 512 320 255 563 481 217 150 198 187
Endoplasmic Reticulum 5 6 1 4 9 8 29 43 36 31 23 25 2 9 6 33 22 22 8 2 8 6 5 11
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 3 2 0 0 4 5 4 5 4 0 0 2 10 4 0 0 0 2 0 3 5
Mitochondria 0 0 1 0 0 0 0 2 9 6 1 25 0 0 0 0 0 0 0 0 0 0 1 1
Nucleus 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1
Nucleolus 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 2 0 0 0 0 0 0 0 1
Peroxisomes 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 2 2 0 1 0 3 6 0 1 4 1 0 0 3
Unique Cell Count 607 480 243 198 261 251 294 302 271 302 178 276 255 300 337 529 332 255 587 498 240 163 214 223
Labelled Cell Count 609 490 246 200 265 257 313 318 295 327 199 313 255 301 338 564 362 281 587 498 240 163 214 223


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 134.2 153.2 132.9 135.4 119.8 84.9 73.5 60.5 53.8 47.4 46.1 40.1 161.5 149.1 136.2 116.9 137.5 137.9 132.3 121.8 113.0
Std Deviation (1e-4) 26.9 31.9 31.8 29.7 22.7 19.7 15.8 13.0 11.9 11.2 10.4 9.5 31.6 33.9 33.3 40.9 41.1 40.9 35.8 35.0 35.8
Intensity Change (Log2) – – – 0.03 -0.15 -0.65 -0.85 -1.14 -1.31 -1.49 -1.53 -1.73 0.28 0.17 0.04 -0.18 0.05 0.05 -0.01 -0.13 -0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700050100150WT3HU80HU120HU160050100150WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3050100150WT1AF100AF140AF180050100150
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 4.0 0 0 3.3 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 3.5 3.3 3.0 4.1 5.5 4.3 0 0 0 0 1.8 0
Cytoplasm -2.2 -2.8 -2.3 -5.4 -6.8 -7.5 -6.7 -8.1 -7.6 -1.3 -2.4 -2.1 -2.4 -2.6 1.0
Endoplasmic Reticulum 0 0 0 4.7 5.9 5.6 4.9 5.5 4.5 0 0 0 3.7 3.8 4.4
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 4.5 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 141.6779 197.4818 180.0105 178.2633 115.0663 148.3772 167.1036 229.316 194.3809 177.9171 175.6726 205.0407 157.0559 236.9239 209.9824 203.3693 148.4067 197.8512
Actin 0.0124 0.0004 0.0019 0.0012 0.0105 0.0007 0.0067 0.0003 0.0044 0.0036 0.0017 0.0011 0.0067 0.0004 0.0004 0.0003 0.1987 0.0034
Bud 0.0037 0.0012 0.0032 0.0026 0.0011 0.0055 0.0023 0.0009 0.0047 0.0028 0.0023 0.0018 0.0026 0.0008 0.0022 0.0015 0.0026 0.0019
Bud Neck 0.0036 0.0012 0.002 0.0011 0.0009 0.0017 0.0009 0.001 0.001 0.0008 0.001 0.0044 0.0009 0.0006 0.0006 0.0062 0.0009 0.0023
Bud Periphery 0.0053 0.0013 0.0027 0.0014 0.0011 0.003 0.0045 0.0007 0.0052 0.0032 0.0024 0.002 0.0019 0.0004 0.0008 0.0005 0.0029 0.0011
Bud Site 0.0085 0.0013 0.0047 0.0006 0.0015 0.0011 0.0016 0.0019 0.0013 0.0018 0.0005 0.0003 0.0027 0.0008 0.0012 0.0002 0.0031 0.0002
Cell Periphery 0.0743 0.0564 0.056 0.0414 0.009 0.0059 0.0495 0.0259 0.0192 0.0502 0.0086 0.0131 0.0524 0.018 0.0261 0.0022 0.001 0.0025
Cytoplasm 0.4143 0.7194 0.5572 0.3508 0.3307 0.6003 0.6582 0.881 0.7682 0.5704 0.7767 0.8039 0.5818 0.9213 0.8185 0.7888 0.614 0.9378
Cytoplasmic Foci 0.0123 0.0005 0.0075 0.0033 0.0962 0.0118 0.0101 0.0039 0.0125 0.0214 0.0113 0.0031 0.0783 0.0005 0.001 0.0023 0.011 0.0038
Eisosomes 0.0021 0 0.0002 0 0.0003 0.0001 0.0019 0.0007 0.0004 0.0001 0 0 0.0038 0 0 0 0.0005 0
Endoplasmic Reticulum 0.0276 0.0088 0.0044 0.003 0.0082 0.0026 0.0482 0.0051 0.014 0.0043 0.0067 0.0328 0.0116 0.0034 0.001 0.0013 0.0056 0.0054
Endosome 0.0054 0.0013 0.0034 0.0103 0.0072 0.0067 0.0091 0.0009 0.0136 0.0221 0.0308 0.0076 0.0036 0.0006 0.0018 0.0081 0.0165 0.0031
Golgi 0.0017 0.0001 0.0013 0.0048 0.0072 0.0004 0.0026 0.0001 0.0017 0.009 0.0014 0.0007 0.0027 0.0001 0.0002 0.0001 0.0692 0.0006
Lipid Particles 0.0071 0.001 0.0025 0.0007 0.0168 0.0008 0.005 0.0013 0.004 0.0059 0.0026 0.0009 0.0114 0.0006 0.0013 0.0001 0.0033 0.0006
Mitochondria 0.0233 0.0005 0.0095 0.0027 0.0259 0.0132 0.0073 0.001 0.0066 0.0286 0.001 0.005 0.0347 0.0002 0.0004 0.0002 0.0256 0.0017
None 0.0087 0.0002 0.0023 0.0006 0.0175 0.0175 0.01 0.0008 0.0053 0.0052 0.0074 0.0043 0.0328 0.0004 0.0006 0.0002 0.0009 0.001
Nuclear Periphery 0.0501 0.0112 0.0122 0.016 0.023 0.0084 0.0201 0.0034 0.0094 0.0147 0.0098 0.0174 0.0107 0.0048 0.0055 0.0019 0.0134 0.0066
Nucleolus 0.0155 0.0005 0.0076 0.0021 0.0782 0.0543 0.0071 0.0019 0.0033 0.0025 0.0009 0.0047 0.0418 0.0002 0.0013 0.0001 0.0005 0.0005
Nucleus 0.019 0.0053 0.0109 0.0129 0.0167 0.0281 0.0109 0.0033 0.0065 0.0114 0.0067 0.0199 0.0113 0.0029 0.0078 0.0033 0.0068 0.0057
Peroxisomes 0.0033 0 0.002 0.0002 0.0273 0.0006 0.0005 0.0001 0.0005 0.0006 0.0002 0.0001 0.0028 0 0.0001 0.0001 0.0056 0.0002
Punctate Nuclear 0.0044 0 0.0003 0.0001 0.027 0.001 0.0007 0.0001 0.0005 0.0007 0.0012 0.0002 0.0063 0 0.0001 0 0.0006 0.0003
Vacuole 0.2348 0.1666 0.2529 0.3976 0.1947 0.1671 0.1265 0.0623 0.1033 0.2058 0.1057 0.0609 0.0881 0.0418 0.1106 0.1386 0.0137 0.0157
Vacuole Periphery 0.0624 0.0225 0.0551 0.1468 0.0988 0.0692 0.0163 0.0034 0.0144 0.0347 0.0213 0.0159 0.0112 0.0022 0.0183 0.0441 0.0038 0.0058

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 1762.8645 1951.2575 2140.8617 1740.5958 1816.2654 1656.4156 1673.4757 1381.8378 1461.4749 1255.9642
Translational Efficiency 1.1824 1.2211 1.1678 1.4613 1.2893 1.2056 1.2487 1.6007 1.2427 1.386

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
101 1267 335 754 1992 254 578 119 2093 1521 913 873

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 8889.84 9752.16 14409.00 13099.53 8746.80 9888.49 13052.82 12536.44 8753.70 9774.93 13550.43 13022.77
Standard Deviation 1506.53 2450.97 2919.75 4019.48 1854.65 2310.30 2809.10 3525.93 1839.62 2428.58 2924.18 3960.55
Intensity Change Log 2 — 0.133564 0.696741 0.559286 — 0.176995 0.577534 0.519301 — 0.155267 0.638852 0.539594

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000118 0.000114 0.000194 0.000969 0.000052 0.000205 0.000200 0.000277 0.000055 0.000129 0.000197 0.000875
Bud Neck 0.001803 0.000713 0.005561 0.002523 0.000376 0.002435 0.004368 0.005888 0.000445 0.001001 0.004806 0.002982
Bud Site 0.001534 0.003769 0.003864 0.015179 0.001838 0.008105 0.004842 0.010113 0.001823 0.004493 0.004483 0.014489
Cell Periphery 0.061188 0.025029 0.075637 0.070775 0.009666 0.038631 0.045964 0.035593 0.012152 0.027300 0.056852 0.065979
Cytoplasm 0.290691 0.702656 0.216058 0.422898 0.803664 0.590337 0.347839 0.243430 0.778910 0.683899 0.299485 0.398434
Cytoplasmic Foci 0.031920 0.009226 0.023694 0.009380 0.007097 0.022741 0.009742 0.017428 0.008295 0.011483 0.014861 0.010477
Eisosomes 0.000007 0.000003 0.000023 0.000013 0.000001 0.000011 0.000010 0.000014 0.000001 0.000005 0.000015 0.000013
Endoplasmic Reticulum 0.000266 0.000646 0.000375 0.000406 0.000578 0.000346 0.000227 0.000196 0.000563 0.000596 0.000281 0.000377
Endosome 0.000752 0.000528 0.000819 0.001604 0.000447 0.000933 0.000675 0.001645 0.000462 0.000595 0.000728 0.001609
Golgi 0.095490 0.054121 0.052553 0.019278 0.035103 0.059711 0.025921 0.016870 0.038017 0.055054 0.035693 0.018950
Lipid Particles 0.053744 0.017212 0.040063 0.039086 0.010670 0.028268 0.021128 0.023248 0.012749 0.019059 0.028075 0.036927
Mitochondria 0.000092 0.000249 0.000161 0.001748 0.000131 0.000855 0.000166 0.000293 0.000129 0.000350 0.000164 0.001550
Mitotic Spindle 0.000623 0.000927 0.002069 0.001059 0.000782 0.002563 0.001636 0.000639 0.000774 0.001200 0.001795 0.001002
None 0.001754 0.003232 0.001154 0.002238 0.001744 0.003009 0.001836 0.000637 0.001745 0.003195 0.001585 0.002020
Nuclear Periphery 0.002522 0.000859 0.004716 0.000709 0.000580 0.001563 0.002109 0.000797 0.000674 0.000977 0.003066 0.000721
Nuclear Periphery Foci 0.026091 0.012037 0.016004 0.005584 0.011045 0.017017 0.010776 0.006714 0.011771 0.012869 0.012694 0.005738
Nucleolus 0.000097 0.000103 0.000160 0.000278 0.000054 0.001534 0.000211 0.000484 0.000056 0.000342 0.000192 0.000306
Nucleus 0.023939 0.012564 0.019013 0.012328 0.009740 0.024065 0.022526 0.019466 0.010425 0.014485 0.021237 0.013301
Peroxisomes 0.000008 0.000030 0.000021 0.000287 0.000013 0.000875 0.000023 0.000066 0.000012 0.000171 0.000022 0.000256
Vacuole 0.319183 0.090323 0.433877 0.351695 0.060332 0.155357 0.443896 0.556551 0.072823 0.101183 0.440220 0.379619
Vacuole Periphery 0.088179 0.065659 0.103985 0.041964 0.046087 0.041437 0.055904 0.059652 0.048118 0.061614 0.073546 0.044375

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.12 -3.86 -2.32 -2.31 -2.08 -3.32 -7.45 -3.11 -1.13 -1.23 -4.69 -9.14 -2.59 -2.35 -2.09
Bud Neck 3.38 -6.84 -2.33 -5.48 4.57 -5.14 -9.89 -5.47 -3.80 -1.23 -5.95 -13.40 -8.00 -6.42 4.34
Bud Site -4.89 -4.41 -7.70 -6.24 -6.16 -2.73 -5.69 -4.38 -0.93 -2.28 -4.91 -6.55 -8.15 -6.17 -5.90
Cell Periphery 4.74 -1.26 -0.67 -9.63 0.88 -7.44 -8.10 -2.78 1.67 1.62 -9.57 -12.27 -13.43 -8.68 -2.15
Cytoplasm -12.52 2.47 -3.57 17.94 -9.98 9.51 29.06 19.74 9.08 2.93 8.91 37.20 28.16 19.45 -6.07
Cytoplasmic Foci 3.60 0.57 3.10 -1.11 4.33 -6.09 -4.64 -2.71 -0.09 -1.79 -3.57 -6.64 -2.49 -0.78 2.15
Eisosomes 2.19 -5.63 -2.84 -3.99 2.82 -2.67 -10.56 -3.02 -0.78 -1.19 -3.45 -11.42 -6.01 -3.81 0.75
Endoplasmic Reticulum -3.84 -1.16 -2.09 2.75 -0.79 1.79 3.43 3.82 2.38 1.53 -0.21 2.98 2.01 3.02 -2.60
Endosome 2.22 -0.71 -1.68 -2.20 -1.53 -3.06 -4.35 -2.27 -0.97 -1.58 -2.41 -5.46 -2.64 -2.29 -1.86
Golgi 3.61 3.94 7.16 12.58 8.67 -4.30 5.66 9.40 8.18 4.02 -6.13 2.35 10.32 14.55 7.45
Lipid Particles 4.78 1.65 1.92 -6.82 0.55 -5.20 -5.44 -3.51 1.68 -0.37 -4.06 -8.71 -9.04 -6.08 -2.92
Mitochondria -4.70 -3.35 -2.43 -2.21 -2.32 -1.46 -3.57 -1.33 0.98 -0.79 -2.56 -3.82 -2.43 -2.04 -2.31
Mitotic Spindle -2.66 -5.76 -1.12 -0.28 2.43 -3.17 -2.55 0.20 3.13 2.52 -2.89 -3.76 -0.66 0.67 2.45
None -3.46 2.19 -0.97 1.16 -2.04 -3.53 0.16 5.52 5.81 1.33 -4.98 0.67 -0.83 1.69 -1.09
Nuclear Periphery 5.92 -5.08 6.30 1.32 10.40 -5.26 -7.03 -1.91 3.07 5.02 -4.06 -11.85 -0.79 2.48 11.09
Nuclear Periphery Foci 4.68 3.20 7.22 7.32 8.48 -3.10 0.45 3.55 4.99 2.86 -1.08 -0.76 8.26 8.80 8.62
Nucleolus -0.20 -5.08 -3.25 -3.12 -2.26 -1.32 -6.93 -2.46 1.11 -1.48 -1.42 -8.73 -4.49 0.63 -2.09
Nucleus 3.05 0.39 2.21 -1.10 2.21 -4.37 -7.09 -3.57 -0.59 0.94 -3.31 -7.84 -3.30 -1.05 4.44
Peroxisomes -5.32 -5.21 -2.49 -2.28 -2.35 -1.12 -3.93 -3.05 1.05 -2.43 -1.23 -4.86 -2.54 -0.34 -2.41
Vacuole 8.62 -4.02 -1.44 -23.29 4.38 -6.98 -28.65 -17.13 -12.27 -3.41 -5.39 -35.30 -29.13 -25.43 3.92
Vacuole Periphery 1.29 -0.88 3.17 6.12 8.45 1.10 -0.43 0.34 -0.33 0.54 -3.70 -4.58 2.29 5.58 6.31
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Gamma subunit of translational elongation factor eEF1B; stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing eEF1A (Tef1p/Tef2p) from the ribosomal complex
Localization
Cell Percentages cytoplasm (100%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-1

Tef4

Tef4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tef4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available