Standard name
Human Ortholog
Description Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.06 0.07 0.06 0.09 0.07 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0.06 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.09 0.09 0 0.07 0.14
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.65 0.71 0.71 0.65 0.28 0.37 0.43 0.51 0.7 0.66 0.78 0.76 0.86 0.73 0.84 0.52 0.41 0.47 0.56 0.64 0.57 0.68 0.7 0.42
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07
Endosome 0.17 0.1 0.1 0.15 0.16 0.11 0.06 0.07 0.05 0.06 0 0.06 0 0 0 0 0 0 0.12 0.07 0.09 0.1 0.07 0.1
Golgi 0 0.05 0 0.09 0 0 0 0 0 0 0 0 0.06 0.12 0.12 0.1 0.18 0.14 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0.2 0.14 0.07 0.08 0 0.06 0 0.07 0 0.05 0 0.13 0.2 0.18 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0.09 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0.11 0.12 0.11 0.09 0.06 0.11 0.11 0.05 0.11
Vac/Vac Membrane 0 0 0 0 0.36 0.43 0.5 0.39 0.23 0.25 0.12 0.11 0 0 0 0.24 0.29 0.18 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 17 18 15 13 10 3 5 7 4 5 3 10 5 7 8 1 2 0 12 6 8 1 3 8
Bud 16 7 16 4 6 5 1 2 4 5 4 8 6 2 5 1 0 4 30 29 26 5 20 42
Bud Neck 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 5 4 0 0 4
Bud Site 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 10 7 7 0 1 1 2 2 3 4 10 4 1 7 10 5 5 0 1 0 0 0 0
Cytoplasm 173 182 189 89 41 94 146 164 141 202 162 246 235 177 242 181 102 80 187 217 166 119 200 123
Endoplasmic Reticulum 3 5 4 3 0 5 1 0 3 7 7 3 3 6 3 11 5 6 7 8 9 4 8 19
Endosome 46 26 26 20 23 27 20 22 10 18 5 19 11 7 3 13 4 4 40 23 26 17 19 28
Golgi 4 13 4 12 5 4 11 6 2 2 2 6 15 29 35 36 44 24 1 2 2 0 2 3
Mitochondria 11 2 4 1 1 0 1 2 0 0 2 3 2 4 2 13 4 4 4 5 3 1 1 3
Nucleus 3 8 0 0 1 1 4 3 0 0 0 1 1 0 1 0 0 0 0 1 0 0 0 1
Nuclear Periphery 1 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1
Nucleolus 11 3 5 2 30 34 25 27 9 19 9 22 4 11 3 44 49 31 0 0 0 0 0 0
Peroxisomes 3 4 9 4 4 3 1 0 0 0 0 0 3 1 3 4 2 0 0 0 1 0 1 4
SpindlePole 9 5 23 9 10 6 5 4 0 3 0 1 3 4 3 40 30 18 31 19 33 18 14 31
Vac/Vac Membrane 10 8 10 3 54 107 169 125 45 78 24 36 6 6 2 83 73 31 4 10 6 2 5 15
Unique Cell Count 267 255 265 137 148 251 337 319 200 308 207 323 272 244 289 351 250 169 336 338 295 175 285 295
Labelled Cell Count 311 301 313 167 185 290 390 364 220 342 222 365 298 255 317 437 320 207 336 338 295 175 285 295


Cytoplasm, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 12.0 13.1 14.2 19.1 29.9 34.3 31.4 29.7 29.8 26.8 27.8 26.1 20.2 27.8 30.3 33.0 37.8 37.6 11.4 12.3 15.2
Std Deviation (1e-4) 7.6 8.3 7.8 10.0 13.7 13.2 13.5 10.7 12.2 8.8 9.4 7.8 12.7 14.2 13.5 11.9 13.7 13.3 5.3 6.3 8.6
Intensity Change (Log2) – – – 0.42 1.07 1.27 1.14 1.06 1.07 0.91 0.97 0.87 0.5 0.97 1.09 1.21 1.41 1.4 -0.32 -0.21 0.1


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 1.4 0.4 -2.8 -2.8 -2.2 -2.0 -2.6 -2.4 -1.5 -2.3 -1.5 -1.7 -4.2 -3.1 -3.1
Bud -1.4 -0.9 -2.3 -4.2 -3.8 -2.1 -2.8 -2.2 -2.2 -2.2 -3.2 -2.7 -4.3 -3.9 -1.8
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0.3 -1.0 0 -0.2 0.2 -0.5 0
Cytoplasm -1.3 -8.6 -7.7 -6.9 -4.9 -0.2 -1.5 1.7 1.3 4.3 0.3 3.5 -5.0 -7.0 -5.0
Endoplasmic Reticulum 0 0 0 0 0 0 0.7 0 0 0 0 0 1.3 0 0
Endosome 1.4 1.7 0.4 -1.8 -1.3 -1.9 -1.8 -3.2 -1.8 -2.6 -3.2 -4.6 -3.1 -4.0 -3.0
Golgi 3.5 0 0 1.4 0 0 0 0 0 2.5 4.7 4.9 4.4 6.3 5.2
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 1.6 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 6.4 5.0 3.1 3.5 1.6 2.6 1.6 2.8 0 1.7 0 4.8 6.6 6.1
Peroxisomes 0 0 -1.7 0 0 0 0 0 0 -1.8 0 -1.9 -1.9 -2.0 0
SpindlePole -0.7 -0.7 -3.1 -4.2 -4.3 -4.3 -4.4 -4.3 -5.1 -4.1 -3.5 -4.2 1.1 1.2 0.7
Vacuole 0 8.8 10.5 12.4 10.1 6.2 7.1 3.3 3.3 -1.1 -0.8 -2.5 6.8 7.8 5.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.9297 4.5937 6.0126 5.5534 5.8155 5.2214 5.4855 6.3444 5.7227 4.3582 5.4253 6.4161 5.2419 4.1152 4.6799 4.6477 4.1627 4.4432
Actin 0.042 0.013 0.0037 0.0007 0.0008 0.002 0.0226 0.001 0.0071 0.0019 0.0131 0.0142 0.0212 0.0005 0.0095 0.0002 0.0004 0.0027
Bud 0.0015 0.0089 0.0024 0.0011 0.0004 0.0023 0.0044 0.0111 0.0144 0.0237 0.0095 0.0028 0.0013 0.0023 0.0013 0.0003 0.0014 0.001
Bud Neck 0.0019 0.0011 0.0008 0.0007 0.0006 0.0015 0.0091 0.0006 0.0013 0.0011 0.0014 0.0023 0.005 0.0004 0.0016 0.0001 0.0002 0.0024
Bud Periphery 0.0014 0.0079 0.0026 0.0019 0.0002 0.0097 0.0064 0.017 0.0181 0.032 0.0176 0.0064 0.0011 0.0016 0.0032 0.0002 0.0016 0.0013
Bud Site 0.0097 0.0465 0.0129 0.0013 0.0003 0.0005 0.0068 0.0408 0.0153 0.014 0.0024 0.0009 0.0053 0.0047 0.0116 0 0.0004 0.0004
Cell Periphery 0.0009 0.0014 0.0005 0.0006 0.0001 0.0004 0.0014 0.0013 0.001 0.0007 0.0009 0.0002 0.0004 0.0002 0.0119 0.0002 0.0003 0.0004
Cytoplasm 0.3682 0.4806 0.3737 0.3777 0.4248 0.5196 0.3804 0.4408 0.409 0.4852 0.458 0.5114 0.1574 0.4367 0.3648 0.5358 0.3645 0.4369
Cytoplasmic Foci 0.173 0.0918 0.2301 0.2118 0.0902 0.1552 0.1558 0.1546 0.1702 0.094 0.1143 0.162 0.0369 0.0862 0.0752 0.0229 0.0231 0.0858
Eisosomes 0.003 0.0003 0.0001 0 0 0 0.0002 0.0001 0.0003 0 0.0002 0.0001 0.0002 0 0.0022 0.0002 0 0.0001
Endoplasmic Reticulum 0.0135 0.0031 0.0065 0.0044 0.002 0.0119 0.0124 0.0021 0.005 0.0057 0.0028 0.0059 0.0564 0.0082 0.0042 0.0062 0.002 0.0058
Endosome 0.1326 0.0635 0.1456 0.2224 0.2278 0.101 0.1303 0.0717 0.0954 0.0847 0.1257 0.1097 0.3406 0.0372 0.0392 0.0241 0.1627 0.0533
Golgi 0.0135 0.0046 0.0112 0.0081 0.0098 0.0061 0.014 0.0048 0.0116 0.0038 0.0074 0.0059 0.0162 0.0007 0.0037 0.0007 0.0019 0.0048
Lipid Particles 0.0222 0.0034 0.011 0.0045 0.038 0.0029 0.0092 0.0013 0.0047 0.0008 0.0105 0.0035 0.0121 0.0002 0.0093 0.0032 0.0053 0.0014
Mitochondria 0.0293 0.003 0.0109 0.0009 0.0029 0.0014 0.0196 0.0008 0.0083 0.0014 0.004 0.0026 0.0204 0.0004 0.0016 0.0008 0.0066 0.0044
None 0.1261 0.2278 0.1102 0.1075 0.1071 0.1086 0.1672 0.191 0.1702 0.1521 0.1982 0.1296 0.0636 0.3644 0.4474 0.3949 0.3825 0.3642
Nuclear Periphery 0.0039 0.001 0.0027 0.0016 0.0111 0.003 0.006 0.0013 0.0021 0.0034 0.001 0.0017 0.1244 0.0179 0.0012 0.0012 0.001 0.001
Nucleolus 0.0019 0.0026 0.0005 0.0002 0.0019 0.0002 0.0008 0.0004 0.0006 0.0008 0.0012 0.0002 0.0033 0.0001 0.0003 0.0001 0.0003 0.0002
Nucleus 0.0028 0.003 0.0018 0.0013 0.03 0.0029 0.0027 0.004 0.0022 0.0034 0.0014 0.0023 0.0652 0.0022 0.001 0.0006 0.001 0.0011
Peroxisomes 0.0115 0.0031 0.0082 0.002 0.0115 0.0046 0.0073 0.0096 0.0173 0.0027 0.0026 0.0058 0.0055 0.0019 0.0016 0.0005 0.0005 0.0007
Punctate Nuclear 0.0177 0.0059 0.0039 0.001 0.0016 0.0015 0.0033 0.0017 0.006 0.0009 0.001 0.0015 0.0293 0.0006 0.0012 0.0004 0.0003 0.0007
Vacuole 0.0211 0.0252 0.0535 0.0395 0.0308 0.0584 0.0355 0.0416 0.0359 0.0787 0.0221 0.0281 0.0213 0.0212 0.0071 0.0061 0.037 0.0285
Vacuole Periphery 0.0022 0.0023 0.0072 0.0109 0.008 0.0064 0.0047 0.0024 0.0039 0.0089 0.0046 0.0031 0.013 0.0126 0.001 0.0011 0.007 0.0029

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.1395 15.3223 25.5821 38.305 43.5202 44.9683 38.2469 48.3605 70.2733 65.7248
Translational Efficiency 1.323 1.3952 1.1555 1.7128 1.5844 1.3226 1.4809 1.4005 1.459 1.5091

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
303 313 114 2105 2322 1839 338 1401 2625 2152 452 3506

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1546.67 1323.01 2180.15 1377.23 1331.99 1158.87 2488.15 1488.34 1356.77 1182.74 2410.47 1421.63
Standard Deviation 554.17 437.37 603.06 480.11 484.90 361.79 562.10 510.61 498.14 378.19 588.12 495.52
Intensity Change Log 2 — -0.225341 0.495262 -0.167396 — -0.200865 0.901490 0.160121 — -0.213964 0.697500 -0.006575

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001221 0.000539 0.000542 0.000863 0.000347 0.001023 0.000678 0.002084 0.000448 0.000953 0.000644 0.001350
Bud Neck 0.005845 0.004770 0.010969 0.005229 0.007816 0.006548 0.009724 0.005040 0.007589 0.006289 0.010038 0.005154
Bud Site 0.081955 0.054751 0.035985 0.063776 0.089937 0.071552 0.049480 0.079383 0.089015 0.069108 0.046077 0.070012
Cell Periphery 0.001736 0.000326 0.001173 0.000271 0.000802 0.000358 0.000465 0.000348 0.000910 0.000353 0.000644 0.000301
Cytoplasm 0.397172* 0.422803* 0.061396 0.518877* 0.484004* 0.464074* 0.080012 0.408509* 0.473981* 0.458072* 0.075317 0.474774*
Cytoplasmic Foci 0.290639* 0.346289* 0.487361* 0.198635* 0.282110* 0.282307* 0.625020* 0.274402* 0.283095* 0.291613* 0.590301* 0.228911*
Eisosomes 0.000034 0.000023 0.000047 0.000008 0.000010 0.000026 0.000017 0.000011 0.000013 0.000025 0.000025 0.000010
Endoplasmic Reticulum 0.003501 0.000442 0.000773 0.000333 0.000672 0.000923 0.000284 0.000643 0.000998 0.000853 0.000407 0.000457
Endosome 0.035546 0.050134 0.039141 0.036999 0.028351 0.058991 0.027595 0.040658 0.029181 0.057703 0.030507 0.038461
Golgi 0.030323 0.020423 0.012238 0.010695 0.012522 0.019843 0.015576 0.014920 0.014577 0.019927 0.014734 0.012383
Lipid Particles 0.007715 0.005311 0.020350 0.005192 0.002556 0.003396 0.009661 0.007723 0.003151 0.003675 0.012357 0.006203
Mitochondria 0.000808 0.000838 0.000122 0.001186 0.000357 0.001734 0.000130 0.001361 0.000409 0.001604 0.000128 0.001256
Mitotic Spindle 0.002921 0.018205 0.017463 0.044429 0.004814 0.016493 0.022706 0.037137 0.004595 0.016742 0.021384 0.041515
None 0.004085 0.000563 0.000084 0.000462 0.003201 0.001636 0.000065 0.000353 0.003303 0.001480 0.000070 0.000418
Nuclear Periphery 0.000123 0.000049 0.000423 0.000144 0.000036 0.000088 0.000306 0.000152 0.000046 0.000082 0.000336 0.000147
Nuclear Periphery Foci 0.006291 0.001345 0.007617 0.001615 0.002245 0.001662 0.006208 0.001729 0.002712 0.001616 0.006563 0.001661
Nucleolus 0.000689 0.000140 0.000933 0.000181 0.000496 0.000819 0.000210 0.000140 0.000519 0.000720 0.000393 0.000165
Nucleus 0.007337 0.004465 0.014345 0.005785 0.004503 0.003705 0.001191 0.004074 0.004830 0.003815 0.004508 0.005101
Peroxisomes 0.007666 0.011957 0.018404 0.018688 0.005888 0.012228 0.007910 0.020692 0.006093 0.012188 0.010557 0.019489
Vacuole 0.098780 0.046593 0.246533* 0.081264 0.061852 0.045270 0.135173 0.094137 0.066114 0.045462 0.163260 0.086408
Vacuole Periphery 0.015615 0.010035 0.024099 0.005368 0.007481 0.007325 0.007588 0.006504 0.008420 0.007719 0.011752 0.005822

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.00 1.79 1.25 -1.92 -1.21 -4.56 -1.24 -3.25 -1.63 -2.15 -3.78 -0.93 -3.90 -1.05 -1.99
Bud Neck 0.98 -3.20 0.31 -1.04 3.86 2.24 -3.11 4.84 2.65 5.95 2.52 -3.93 4.55 1.83 6.91
Bud Site 2.92 4.68 2.51 -1.26 -4.10 4.45 6.01 3.49 -0.74 -3.47 5.26 7.83 6.49 0.70 -3.82
Cell Periphery 4.60 1.27 4.94 1.02 2.54 4.88 2.83 5.96 0.52 2.64 6.35 1.84 8.09 1.37 3.79
Cytoplasm -0.86 13.20 -5.51 -4.34 -29.03 1.65 29.57 5.13 3.43 -22.98 1.41 34.03 -0.65 -2.15 -37.14
Cytoplasmic Foci -2.18 -3.99 5.63 8.69 7.25 0.01 -13.82 2.49 2.50 14.77 -0.92 -13.83 8.92 10.05 18.02
Eisosomes 1.33 -1.07 3.40 3.19 3.56 -4.64 -1.86 -0.07 4.54 1.80 -3.99 -2.92 2.99 5.60 4.08
Endoplasmic Reticulum 1.95 1.71 2.06 1.18 1.76 -1.40 3.68 0.18 0.79 -0.90 0.61 2.80 2.37 2.18 -0.08
Endosome -1.87 -0.17 0.80 2.93 0.61 -9.54 0.53 -2.71 6.77 -2.58 -9.64 -0.07 -2.02 8.57 -1.14
Golgi 2.10 4.08 5.30 4.31 1.67 -5.15 -0.93 0.39 4.41 1.08 -3.84 0.33 4.17 8.00 2.29
Lipid Particles 1.18 -1.75 1.07 -0.52 1.95 -1.86 -3.78 -5.77 -4.88 0.62 -1.14 -3.96 -6.72 -5.36 2.30
Mitochondria -0.02 0.96 -0.24 -0.28 -3.70 -3.46 3.15 -1.84 1.25 -2.44 -3.34 2.83 -2.75 1.48 -4.28
Mitotic Spindle -3.68 -2.50 -14.98 -6.32 -2.30 -6.56 -4.29 -11.53 -7.94 -2.33 -7.42 -4.92 -18.43 -11.81 -3.36
None 2.06 2.35 2.08 0.05 -7.46 3.42 9.71 8.61 4.08 -3.89 4.11 9.34 8.14 3.81 -8.75
Nuclear Periphery 1.41 -3.36 -1.21 -7.26 3.08 -3.52 -5.55 -7.04 -3.98 3.02 -2.49 -6.88 -9.35 -6.04 4.03
Nuclear Periphery Foci 1.99 -0.73 1.73 -1.30 3.48 1.18 -3.23 0.49 -1.03 3.48 2.06 -3.73 1.44 -0.99 4.55
Nucleolus 1.74 -0.55 1.45 -3.12 2.39 -0.89 3.54 4.93 2.04 1.80 -0.61 1.23 4.59 1.88 2.58
Nucleus 1.02 -0.88 -0.30 -2.98 0.82 1.70 5.86 -0.69 -1.92 -4.68 1.95 -0.16 -3.01 -5.11 -0.63
Peroxisomes -1.51 -1.55 -3.67 -1.30 0.32 -6.84 -1.29 -8.21 -3.14 -6.68 -6.89 -2.11 -10.63 -3.26 -3.59
Vacuole 4.01 -4.94 0.21 -7.22 5.39 4.08 -6.21 -7.20 -11.14 3.15 5.31 -8.35 -7.80 -15.10 5.80
Vacuole Periphery 1.50 -1.04 3.49 2.58 3.18 0.22 0.25 2.31 2.03 1.50 0.83 -1.46 4.88 3.91 3.71
Standard name
Human Ortholog
Description Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway; protein increases in abundance and relative distribution to cytoplasmic foci increases upon DNA replication stress
Localization
Cell Percentages cytoplasm (84%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-8

Ape1

Ape1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ape1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available