Standard name
Human Ortholog
Description Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.09 0.08 0.09 0 0 0 0 0 0
Cytoplasm 0.96 0.97 1.0 0.99 0.99 0.98 0.96 0.94 0.87 – 0.78 0.84 0.99 1.0 0.99 0.97 0.94 0.99 0.93 0.97 0.89 0.81 0.8 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0 0 0 0.09 0.11 0.05 0.25 – 0.36 0.22 0 0 0 0 0 0 0 0 0 0.08 0.08 0.05
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 0 0 1 1 0 – 0 1 0 0 0 1 0 0 0 0 0 2 3 9
Bud 1 1 0 1 1 1 5 7 7 – 9 12 2 2 1 0 1 0 0 0 0 0 6 5
Bud Neck 0 0 3 5 1 2 4 12 3 – 3 6 0 0 0 0 0 0 0 1 1 2 4 3
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 7 5 4 4 4 6 5 6 – 4 6 3 5 7 39 19 15 0 0 1 2 4 3
Cytoplasm 123 153 270 336 388 408 459 490 356 – 288 358 275 512 650 423 210 160 119 160 235 158 325 308
Endoplasmic Reticulum 2 1 0 0 0 0 0 0 1 – 0 0 2 0 2 14 8 6 2 0 1 2 6 5
Endosome 0 0 1 0 0 0 0 1 0 – 2 2 0 2 0 1 0 0 1 0 2 1 1 2
Golgi 0 0 0 1 0 0 0 0 0 – 0 0 1 0 0 1 4 0 0 0 0 1 0 2
Mitochondria 7 1 0 3 3 36 52 25 104 – 131 95 0 0 2 6 2 1 1 1 8 15 32 19
Nucleus 0 1 1 4 1 0 0 3 1 – 2 0 0 1 1 1 2 1 0 0 0 0 0 0
Nuclear Periphery 1 0 0 0 0 0 1 0 0 – 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Nucleolus 1 0 0 0 0 0 0 1 2 – 2 0 0 0 1 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 0 1 0 0
SpindlePole 0 0 0 0 2 0 2 5 0 – 1 3 0 0 0 0 0 0 0 0 1 0 1 3
Vac/Vac Membrane 0 0 0 0 0 2 1 6 0 – 3 6 0 0 0 6 3 2 1 1 5 5 13 18
Unique Cell Count 128 157 271 340 392 417 479 519 408 367 426 278 514 654 438 224 162 128 166 264 196 407 392
Labelled Cell Count 138 164 280 355 400 453 531 556 480 445 489 283 523 664 492 250 185 128 166 264 196 407 392


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.2 4.7 5.3 4.9 5.6 4.3 4.5 4.8 4.0 – 3.8 4.3 4.9 5.0 5.1 7.4 7.8 7.1 4.5 4.4 5.0
Std Deviation (1e-4) 0.5 0.6 1.1 1.4 1.6 1.3 1.3 1.2 1.2 – 1.1 0.7 1.1 0.9 1.0 1.1 1.2 1.1 1.2 0.9 1.5
Intensity Change (Log2) – – – -0.1 0.1 -0.29 -0.23 -0.12 -0.4 – -0.47 -0.3 -0.1 -0.08 -0.04 0.5 0.58 0.43 -0.22 -0.27 -0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.8333 0.3152 -0.1936 0.5053 1.6046 -0.1356 -0.8404 -0.5971 -0.74 -0.58 -0.9128 -0.9404 -0.0164 0.1425 -0.2765 -0.244 -0.3476 0.0141
Actin 0.0575 0.0006 0.0243 0.0204 0.0052 0.0002 0.0315 0.0006 0.011 0.0256 0.0022 0.0014 0.024 0.0047 0.0115 0.0001 0.0001 0.0023
Bud 0.0006 0.0008 0.0048 0.0004 0.0016 0 0.0014 0.0016 0.001 0.0031 0.0005 0.0002 0.0008 0.0001 0.0014 0.0001 0 0.0002
Bud Neck 0.0026 0.0002 0.0032 0.0005 0.0005 0.0002 0.0058 0.0002 0.0004 0.0049 0.0031 0.0006 0.0011 0.0001 0.0015 0.0001 0 0.0003
Bud Periphery 0.0012 0.0009 0.0043 0.0003 0.0013 0 0.0013 0.0012 0.0017 0.0053 0.0005 0.0004 0.001 0.0001 0.0012 0.0001 0 0.0004
Bud Site 0.0041 0.0175 0.0123 0.001 0.0006 0 0.02 0.006 0.0123 0.0118 0.0257 0.0008 0.0089 0.0009 0.0071 0.0001 0 0.0002
Cell Periphery 0.0008 0.0012 0.0008 0.0001 0.0002 0.0001 0.0006 0.0004 0.0004 0.0007 0.0002 0.0001 0.0008 0.0003 0.0003 0.0001 0 0.0001
Cytoplasm 0.3158 0.4787 0.32 0.3153 0.4639 0.4551 0.3826 0.6591 0.4994 0.5708 0.4979 0.6448 0.398 0.674 0.5551 0.6278 0.3417 0.7696
Cytoplasmic Foci 0.0448 0.0048 0.0341 0.0648 0.0041 0.0122 0.0666 0.0144 0.0303 0.0133 0.0416 0.009 0.0206 0.0052 0.0146 0.0073 0.0023 0.0055
Eisosomes 0.0025 0.0005 0.0005 0.0001 0 0.0001 0.0003 0.0001 0.0001 0.0002 0 0.0001 0.0005 0.0002 0.0001 0 0 0.0001
Endoplasmic Reticulum 0.0055 0.002 0.0033 0.0032 0.0047 0.0026 0.0051 0.003 0.0039 0.0042 0.0015 0.0028 0.0081 0.006 0.0039 0.0022 0.0012 0.0032
Endosome 0.0162 0.0016 0.0138 0.041 0.0026 0.0006 0.0427 0.0057 0.0142 0.0231 0.0094 0.0107 0.0499 0.0035 0.0065 0.0056 0.0006 0.015
Golgi 0.0061 0.0001 0.0106 0.037 0.0002 0.0001 0.0159 0.0005 0.0042 0.0116 0.0136 0.0021 0.0153 0.0031 0.0059 0.0001 0 0.0033
Lipid Particles 0.0114 0.0002 0.0152 0.0148 0.0001 0.0005 0.0186 0.0005 0.0036 0.0149 0.0356 0.0037 0.0243 0.0012 0.0016 0.0001 0.0001 0.0022
Mitochondria 0.0047 0.0002 0.0167 0.0058 0.0027 0.0001 0.0064 0.0003 0.0164 0.0264 0.0012 0.0114 0.0107 0.0012 0.0017 0.0001 0.0001 0.0295
None 0.4947 0.4869 0.4886 0.4375 0.3122 0.5271 0.3422 0.2995 0.382 0.261 0.3403 0.3063 0.39 0.296 0.3812 0.3514 0.6527 0.1625
Nuclear Periphery 0.0048 0.0004 0.002 0.0007 0.0754 0.0002 0.0095 0.0007 0.0017 0.0049 0.0002 0.0006 0.0105 0.0009 0.0009 0.0007 0.0003 0.0014
Nucleolus 0.0013 0.0002 0.0075 0.0001 0.0004 0 0.0009 0.0001 0.0004 0.0024 0.0004 0.0005 0.0049 0.0001 0.0002 0 0 0.0002
Nucleus 0.0018 0.0008 0.0047 0.0005 0.1172 0.0003 0.0037 0.0011 0.0018 0.0023 0.0004 0.0009 0.0041 0.0005 0.0007 0.0008 0.0002 0.0006
Peroxisomes 0.0132 0.0001 0.0224 0.0527 0.0002 0.0001 0.0321 0.0003 0.0079 0.0019 0.0236 0.0007 0.0044 0.0001 0.0017 0 0 0.0007
Punctate Nuclear 0.0079 0.0006 0.0071 0.001 0.0019 0.0003 0.0021 0.0007 0.0016 0.001 0.0008 0.0006 0.0125 0.0003 0.0011 0.0003 0.0001 0.0009
Vacuole 0.0019 0.0015 0.0033 0.0023 0.0029 0.0003 0.0081 0.0034 0.0041 0.0037 0.001 0.0017 0.0067 0.0015 0.0015 0.0025 0.0004 0.0012
Vacuole Periphery 0.0005 0.0001 0.0006 0.0005 0.0022 0 0.0028 0.0004 0.0017 0.0071 0.0002 0.0005 0.0029 0.0002 0.0003 0.0004 0.0001 0.0008

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.5951 4.9886 10.7687 10.0498 6.5775 6.0844 10.0879 10.5224 13.2469 11.0582
Translational Efficiency 0.5797 0.644 0.419 0.5402 0.7118 0.8648 0.4723 0.4652 0.5514 0.4657

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
192 1583 1922 893 378 1128 1180 2109 570 2711 3102 3002

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 664.31 724.82 852.62 829.64 682.16 742.48 830.32 811.68 676.15 732.17 844.14 817.02
Standard Deviation 76.08 88.02 94.32 109.64 75.10 91.68 95.03 102.52 75.90 89.98 95.21 105.01
Intensity Change Log 2 — 0.125766 0.360046 0.320629 — 0.122242 0.283557 0.250801 — 0.123982 0.321802 0.285674

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000071 0.000297 0.000171 0.003380 0.000138 0.001154 0.000194 0.000792 0.000116 0.000653 0.000180 0.001562
Bud Neck 0.016367 0.021050 0.004540 0.006502 0.021070 0.043535 0.001195 0.006786 0.019486 0.030406 0.003268 0.006701
Bud Site 0.003529 0.022054 0.011213 0.067174 0.007564 0.031484 0.004945 0.018750 0.006205 0.025978 0.008828 0.033155
Cell Periphery 0.000221 0.000091 0.000079 0.000167 0.000140 0.000178 0.000104 0.000105 0.000167 0.000127 0.000088 0.000123
Cytoplasm 0.549061* 0.519399* 0.576403* 0.548835* 0.451468* 0.413424* 0.663505* 0.731147* 0.484341* 0.475305* 0.609537* 0.676915*
Cytoplasmic Foci 0.254302* 0.238599* 0.007977 0.039230 0.322022* 0.300093* 0.026265 0.017901 0.299211* 0.264186* 0.014934 0.024246
Eisosomes 0.000254 0.000093 0.000020 0.000050 0.000221 0.000212 0.000037 0.000023 0.000232 0.000143 0.000027 0.000031
Endoplasmic Reticulum 0.000591 0.000501 0.001705 0.003576 0.000426 0.000494 0.001443 0.000378 0.000482 0.000498 0.001605 0.001329
Endosome 0.019264 0.029222 0.001183 0.010268 0.032478 0.043938 0.003520 0.001211 0.028027 0.035345 0.002072 0.003905
Golgi 0.000872 0.007418 0.000135 0.006803 0.003131 0.010159 0.000320 0.000263 0.002370 0.008558 0.000205 0.002209
Lipid Particles 0.004700 0.003297 0.000617 0.001091 0.008029 0.003770 0.001017 0.000387 0.006908 0.003493 0.000770 0.000596
Mitochondria 0.006961 0.005242 0.001385 0.004757 0.002760 0.008592 0.000228 0.000999 0.004175 0.006636 0.000945 0.002117
Mitotic Spindle 0.000808 0.003406 0.008867 0.033046 0.000160 0.010734 0.003110 0.011818 0.000378 0.006455 0.006677 0.018133
None 0.001098 0.001340 0.004705 0.002874 0.000960 0.000581 0.003132 0.003829 0.001006 0.001024 0.004106 0.003545
Nuclear Periphery 0.000578 0.000173 0.001317 0.000745 0.000187 0.000090 0.000632 0.000310 0.000319 0.000138 0.001056 0.000440
Nuclear Periphery Foci 0.000641 0.000529 0.000714 0.003135 0.000359 0.000308 0.002226 0.000518 0.000454 0.000437 0.001289 0.001297
Nucleolus 0.001205 0.000713 0.000202 0.000254 0.000608 0.000466 0.000147 0.000176 0.000809 0.000610 0.000181 0.000199
Nucleus 0.069510 0.035116 0.327284* 0.064871 0.042838 0.024204 0.137907* 0.109299 0.051822 0.030576 0.255245* 0.096083
Peroxisomes 0.001893 0.008193 0.000302 0.002157 0.004474 0.016131 0.000412 0.000327 0.003605 0.011496 0.000344 0.000871
Vacuole 0.066401 0.101073 0.051037 0.196660 0.099412 0.088077 0.148053 0.094755 0.088293 0.095665 0.087942 0.125069
Vacuole Periphery 0.001674 0.002196 0.000143 0.004425 0.001555 0.002375 0.001607 0.000224 0.001595 0.002271 0.000700 0.001474

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.72 -5.94 -3.11 -2.55 -2.72 -2.34 -3.32 -1.76 1.54 -0.84 -2.97 -5.48 -3.47 -0.21 -2.66
Bud Neck -1.06 2.79 3.03 12.59 1.43 -5.30 6.22 5.22 13.21 -4.68 -3.79 6.34 6.01 17.43 -1.31
Bud Site -10.83 -3.35 -6.06 -0.64 -4.61 -9.90 2.33 -2.17 8.22 -4.44 -13.33 -0.49 -5.90 5.96 -5.39
Cell Periphery 6.07 6.49 5.24 -2.20 -3.52 -1.91 3.65 5.64 5.61 3.31 3.29 7.69 7.69 4.51 0.99
Cytoplasm 1.76 4.27 5.96 6.71 3.29 2.57 -6.93 -11.49 -19.17 -5.60 0.87 -1.78 -6.41 -10.78 -7.22
Cytoplasmic Foci 1.20 19.34 17.63 37.46 -11.31 1.72 28.69 29.35 41.84 3.95 3.81 34.78 33.86 56.59 -7.75
Eisosomes 7.10 10.14 8.92 6.59 -8.49 0.29 6.14 6.77 16.31 9.08 4.26 9.67 9.64 18.55 -0.42
Endoplasmic Reticulum 0.39 -9.73 -2.59 -2.89 1.55 -0.46 -12.06 -3.13 -0.87 11.38 -0.21 -17.06 -3.19 -3.13 8.07
Endosome -2.85 6.17 5.22 14.21 -3.57 -3.02 9.40 10.02 20.02 7.42 -2.67 11.27 11.29 25.03 0.50
Golgi -9.38 5.97 -1.21 5.46 -2.24 -7.81 6.51 6.71 12.76 0.48 -10.33 7.39 4.61 14.03 -2.17
Lipid Particles 1.91 5.91 5.29 6.19 -4.79 2.56 4.20 4.55 9.94 8.53 3.02 5.36 5.52 11.60 3.96
Mitochondria 0.34 1.19 1.10 3.17 -0.55 -3.59 2.44 2.08 6.36 -1.43 -1.24 1.91 1.85 7.09 -0.30
Mitotic Spindle -2.32 -5.37 -5.16 -4.21 -2.30 -4.75 -4.86 -6.29 0.88 -2.08 -5.58 -7.48 -8.05 -2.60 -2.18
None -0.70 -11.65 -4.17 -3.82 7.57 1.45 -5.94 -9.49 -17.08 -2.43 -0.06 -13.19 -10.48 -12.59 3.55
Nuclear Periphery 1.04 -4.23 -1.24 -9.85 11.17 3.70 -19.14 -15.30 -23.41 6.16 1.36 -10.55 -3.93 -18.24 17.19
Nuclear Periphery Foci 0.35 -1.57 -3.99 -5.47 -3.86 0.34 -12.18 -4.95 -2.56 10.63 0.07 -9.30 -4.92 -5.37 4.22
Nucleolus 0.73 1.50 1.59 3.10 1.77 1.30 4.76 4.55 5.10 -1.23 0.77 2.63 2.75 4.17 1.50
Nucleus 5.01 -36.24 -4.79 -15.83 38.78 5.27 -20.95 -21.85 -33.14 4.27 6.30 -45.51 -19.82 -35.34 32.66
Peroxisomes -9.44 6.26 3.35 11.32 -2.13 -8.54 7.41 7.69 12.81 0.82 -10.64 8.72 8.36 17.44 -1.18
Vacuole -5.69 -3.77 -26.20 -24.88 -25.95 1.58 -13.44 -11.81 -18.02 3.59 -1.60 -9.15 -23.43 -27.76 -17.19
Vacuole Periphery -0.66 2.15 0.53 1.63 -2.01 -2.80 1.35 7.22 10.37 1.00 -2.01 3.51 3.64 7.47 -0.33
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative serine/threonine protein kinase with unknown cellular role; KKQ8 has a paralog, HAL5, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (56%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Kkq8

Kkq8


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Kkq8-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available