Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.15 0.09 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.1 0 0.05 0 0.05 0
Bud 0.06 0.06 0.19 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0.22 0.49 0.38 0.45 0.26 0.19 – 0.12 0.15 0.21 0.2 0.14 0.49 0.63 0.5 0.6 0.34 0.71 0.12 0.23 0.38 0.23 0.2 0.19
Cytoplasm 0.7 0.59 0.51 0.47 0.53 0.67 – 0.66 0.75 0.69 0.75 0.68 0.57 0.59 0.57 0.59 0.85 0.67 0.29 0.46 0.19 0.32 0.29 0.34
Endoplasmic Reticulum 0.25 0.18 0.11 0.31 0.39 0.29 – 0.3 0.19 0.19 0.15 0.24 0.19 0.15 0.17 0 0.06 0 0.39 0.22 0.3 0.28 0.3 0.28
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.09 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 4 5 25 17 6 1 – 8 8 5 11 4 7 2 2 0 0 0 10 7 11 2 12 6
Bud 5 11 32 4 6 4 – 4 4 4 6 4 7 6 2 1 0 0 2 1 2 3 5 7
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 5 7 4 4 2
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 20 95 65 81 58 45 – 45 33 53 55 39 92 124 100 41 18 17 11 51 77 23 46 41
Cytoplasm 62 113 87 85 118 158 – 254 161 171 208 189 107 116 115 40 45 16 29 102 39 33 69 74
Endoplasmic Reticulum 22 34 19 56 87 68 – 117 40 47 42 67 35 29 33 0 3 1 39 48 62 29 70 60
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 1
Golgi 0 0 0 0 0 0 – 0 0 2 0 1 0 0 0 0 0 0 0 0 0 1 5 4
Mitochondria 0 1 1 2 0 2 – 2 6 9 13 7 1 0 0 0 1 0 1 0 1 0 2 1
Nucleus 0 0 0 0 0 0 – 0 0 0 1 1 0 0 2 0 0 0 0 0 0 1 3 1
Nuclear Periphery 0 0 0 1 0 1 – 0 1 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0
Nucleolus 0 0 0 0 3 0 – 0 0 1 1 0 0 0 0 1 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 1 0 2 1 – 3 0 3 0 0 0 1 3 2 5 1 0 0 1 1 6 3
Unique Cell Count 89 193 170 182 223 236 386 215 247 279 276 187 197 200 68 53 24 102 221 206 103 237 215
Labelled Cell Count 113 259 230 246 280 280 433 253 295 337 312 249 278 257 85 73 35 102 221 206 103 237 215


Mitochondria

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 24.4 30.2 19.9 26.0 28.5 29.2 – 27.9 27.3 25.9 24.6 24.7 35.6 40.8 42.6 58.8 56.0 57.2 34.6 34.8 34.9
Std Deviation (1e-4) 7.4 5.8 10.3 6.1 6.4 6.5 – 6.4 6.6 8.2 6.5 7.9 10.9 12.9 14.2 29.9 31.5 26.6 18.3 18.8 17.3
Intensity Change (Log2) – – – 0.39 0.52 0.56 – 0.49 0.46 0.38 0.31 0.31 0.84 1.04 1.1 1.56 1.49 1.52 0.8 0.81 0.81

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP700020406080WT3HU80HU120HU160020406080WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3020406080WT1AF100AF140AF180020406080
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -1.6 -4.4 -5.8 – -5.8 -3.8 -4.9 -4.1 -5.5 -3.6 -5.0 -5.1 -3.3 -3.0 0
Bud -5.1 -5.4 -6.0 – -7.9 -5.7 -6.1 -6.2 -6.5 -4.6 -4.9 -5.9 -3.5 -3.4 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 1.2 -2.6 -4.3 – -7.2 -5.1 -3.7 -4.3 -5.8 2.1 4.7 2.3 3.1 -0.6 3.0
Cytoplasm -0.8 0.3 3.2 – 3.3 4.8 3.7 5.1 3.7 1.1 1.5 1.2 1.1 4.4 1.4
Endoplasmic Reticulum 4.5 6.2 4.3 – 4.8 2.0 2.2 1.2 3.4 2.0 1.0 1.5 -2.9 -1.2 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 – 0 0 0 2.4 0 0 0 0 0 0 0
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 24.1915 27.2059 24.6365 24.6791 21.883 26.2416 24.1319 27.9316 24.1575 27.1053 22.6325 25.8192 26.3112 27.6178 26.0298 21.5911 26.5773 27.1041
Actin 0.046 0.0148 0.0374 0.0455 0.0652 0.0374 0.0338 0.0268 0.0534 0.014 0.0366 0.0296 0.0365 0.0203 0.0633 0.1057 0.0287 0.0583
Bud 0.0075 0.0009 0.0156 0.0105 0.0028 0.0017 0.0026 0.002 0.0152 0.0048 0.0045 0.0009 0.0035 0.0013 0.0176 0.0046 0.0012 0.0011
Bud Neck 0.0072 0.007 0.019 0.0157 0.0397 0.1173 0.0115 0.0061 0.0097 0.0291 0.0285 0.1324 0.0099 0.0063 0.0115 0.0105 0.0168 0.1399
Bud Periphery 0.0213 0.0022 0.0518 0.0433 0.0088 0.0121 0.0098 0.0056 0.0601 0.0462 0.0274 0.0079 0.0134 0.0026 0.0654 0.0309 0.0119 0.0097
Bud Site 0.0175 0.0988 0.0188 0.0087 0.0242 0.0014 0.012 0.0798 0.0284 0.0017 0.0023 0.0017 0.0146 0.1152 0.027 0.0087 0.0012 0.0011
Cell Periphery 0.1493 0.2263 0.2445 0.238 0.1241 0.1547 0.1905 0.281 0.2992 0.3255 0.2575 0.1759 0.1788 0.2338 0.2547 0.2146 0.1822 0.1109
Cytoplasm 0.4566 0.4727 0.3999 0.2363 0.4271 0.3823 0.3502 0.3813 0.3328 0.295 0.2958 0.2995 0.3884 0.4724 0.3692 0.2453 0.3352 0.3051
Cytoplasmic Foci 0.0054 0.0015 0.0073 0.0038 0.0451 0.0103 0.0151 0.0024 0.0059 0.0006 0.0023 0.0027 0.0081 0.0018 0.0037 0.0063 0.0176 0.0053
Eisosomes 0.0017 0.0014 0.001 0.001 0.0009 0.0015 0.0042 0.0018 0.0019 0.001 0.005 0.0017 0.0014 0.0014 0.002 0.0017 0.0025 0.0014
Endoplasmic Reticulum 0.2042 0.1387 0.1344 0.2821 0.1858 0.2431 0.2688 0.1659 0.1258 0.238 0.2656 0.3056 0.2634 0.117 0.1456 0.2075 0.3376 0.3285
Endosome 0.0105 0.0006 0.011 0.0165 0.0095 0.0028 0.0165 0.0013 0.0021 0.0004 0.0124 0.0016 0.0073 0.0008 0.0034 0.0147 0.0045 0.0077
Golgi 0.01 0.0031 0.0081 0.0253 0.011 0.0105 0.0122 0.0049 0.0048 0.0014 0.0164 0.0059 0.0078 0.0043 0.0043 0.013 0.0106 0.0115
Lipid Particles 0.0148 0.017 0.0142 0.0338 0.0238 0.0109 0.0259 0.0234 0.0172 0.0106 0.0179 0.0173 0.0151 0.0112 0.0132 0.0439 0.0165 0.0074
Mitochondria 0.0129 0.0001 0.0134 0.0116 0.0087 0.002 0.0075 0.0005 0.0125 0.0001 0.0053 0.0033 0.0125 0.0002 0.0014 0.0562 0.0006 0.0007
None 0.0036 0.0003 0.0006 0.0004 0.0014 0.0006 0.003 0.0002 0.0026 0.0002 0.0004 0.0003 0.009 0.0002 0.0015 0.0019 0.0209 0.0006
Nuclear Periphery 0.0116 0.0063 0.0075 0.0065 0.0033 0.004 0.0111 0.0057 0.0066 0.0053 0.0051 0.0046 0.0089 0.0051 0.0066 0.0083 0.0043 0.0048
Nucleolus 0.0007 0.0002 0.0004 0.0003 0.0002 0.0003 0.0009 0.0002 0.0011 0.0001 0.0002 0.0002 0.0003 0.0001 0.0001 0.0013 0.0002 0.0001
Nucleus 0.0023 0.001 0.0019 0.0015 0.0011 0.0012 0.0029 0.0009 0.002 0.001 0.001 0.0013 0.0018 0.001 0.0015 0.002 0.0007 0.0012
Peroxisomes 0.0013 0.0001 0.001 0.0005 0.0101 0.0003 0.002 0.0001 0.0051 0 0.0002 0.0002 0.0027 0.0001 0.0007 0.0063 0.0013 0.0003
Punctate Nuclear 0.0006 0.0002 0.0004 0.0003 0.0019 0.0003 0.0023 0.0002 0.0004 0.0001 0.0002 0.0002 0.0035 0.0002 0.0006 0.0035 0.0024 0.0008
Vacuole 0.0137 0.0069 0.0108 0.0168 0.005 0.0051 0.016 0.0096 0.0125 0.0243 0.0133 0.0067 0.012 0.0045 0.0065 0.0102 0.0026 0.0033
Vacuole Periphery 0.0013 0.0002 0.0008 0.0016 0.0004 0.0004 0.0012 0.0002 0.0006 0.0007 0.0021 0.0004 0.0011 0.0001 0.0004 0.0029 0.0003 0.0004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 14.5533 7.0962 10.5314 26.1497 22.2997 37.0242 26.3083 34.7056 42.1303 38.6863
Translational Efficiency 2.6529 4.7676 3.4738 1.3144 1.5965 1.5426 2.1698 1.8704 1.4715 1.7445

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1485 911 263 1300 395 1563 1330 1497 1880 2474 1593 2797

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1705.04 2061.95 3717.47 3940.60 2446.48 1915.90 2963.40 3740.99 1860.82 1969.68 3087.89 3833.77
Standard Deviation 393.56 501.51 604.33 946.99 563.49 362.84 520.40 965.28 529.43 425.15 603.97 961.99
Intensity Change Log 2 — 0.274204 1.124516 1.208610 — -0.352685 0.276546 0.612713 — -0.061651 0.686396 0.887765

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003661 0.007882 0.003914 0.007006 0.003601 0.006613 0.008059 0.006283 0.003648 0.007080 0.007374 0.006619
Bud Neck 0.006837 0.011782 0.012772 0.008880 0.005472 0.009750 0.010755 0.007517 0.006550 0.010498 0.011088 0.008150
Bud Site 0.086598 0.082567 0.015838 0.081072 0.035460 0.073547 0.042160 0.053235 0.075853 0.076868 0.037814 0.066174
Cell Periphery 0.278213 0.441667 0.631549 0.527715 0.485550 0.451025 0.640584 0.625088 0.321776 0.447579 0.639092 0.579831
Cytoplasm 0.149173 0.072442 0.002735 0.104810 0.008770 0.078354 0.044967 0.084303 0.119673 0.076177 0.037995 0.093834
Cytoplasmic Foci 0.045747 0.013089 0.000818 0.005008 0.005739 0.013538 0.002015 0.002733 0.037341 0.013373 0.001817 0.003790
Eisosomes 0.000520 0.001438 0.004182 0.001181 0.000795 0.001466 0.002861 0.001299 0.000578 0.001456 0.003079 0.001244
Endoplasmic Reticulum 0.170808 0.153079 0.027822 0.008752 0.224003 0.186362 0.036619 0.015328 0.181985 0.174106 0.035166 0.012272
Endosome 0.018862 0.010558 0.003689 0.002332 0.010103 0.009503 0.002855 0.003219 0.017022 0.009891 0.002992 0.002807
Golgi 0.035395 0.017085 0.016612 0.006094 0.058172 0.010136 0.004143 0.005518 0.040181 0.012695 0.006202 0.005786
Lipid Particles 0.129459 0.128154 0.103917 0.134459 0.075880 0.106192 0.111273 0.103628 0.118201 0.114279 0.110058 0.117958
Mitochondria 0.002168 0.002131 0.000221 0.000649 0.002369 0.003357 0.000835 0.001291 0.002210 0.002906 0.000734 0.000992
Mitotic Spindle 0.001622 0.002352 0.001110 0.002599 0.001886 0.001652 0.001492 0.001493 0.001678 0.001910 0.001429 0.002007
None 0.001258 0.000341 0.000109 0.000303 0.000279 0.000273 0.000219 0.000276 0.001052 0.000298 0.000201 0.000288
Nuclear Periphery 0.001286 0.002664 0.004809 0.002817 0.002834 0.002383 0.004361 0.003086 0.001611 0.002486 0.004435 0.002961
Nuclear Periphery Foci 0.007819 0.004864 0.002968 0.002423 0.003645 0.002248 0.001891 0.002866 0.006942 0.003211 0.002069 0.002660
Nucleolus 0.000146 0.000108 0.000059 0.000099 0.000103 0.000116 0.000098 0.000112 0.000137 0.000113 0.000091 0.000106
Nucleus 0.001776 0.001639 0.001137 0.004131 0.002542 0.001408 0.002447 0.002671 0.001937 0.001493 0.002231 0.003349
Peroxisomes 0.008859 0.008620 0.000119 0.000968 0.000588 0.013107 0.002909 0.001845 0.007122 0.011455 0.002449 0.001437
Vacuole 0.033491 0.030519 0.154612 0.094217 0.036684 0.022084 0.076022 0.073102 0.034162 0.025190 0.088997 0.082916
Vacuole Periphery 0.016302 0.007020 0.011008 0.004486 0.035524 0.006885 0.003435 0.005108 0.020340 0.006935 0.004685 0.004819

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.07 -0.55 -5.87 0.64 -3.59 -3.23 -4.00 -2.44 0.27 1.62 -7.09 -5.28 -5.62 0.46 0.86
Bud Neck -3.98 -3.85 -3.33 1.65 2.05 -3.95 -4.72 -1.97 2.36 3.37 -5.61 -6.04 -3.22 2.64 3.37
Bud Site 0.57 15.31 0.21 -0.34 -12.56 -6.45 -1.39 -3.22 3.72 -2.38 -0.27 8.96 1.60 1.94 -7.57
Cell Periphery -13.00 -23.77 -19.73 -5.51 7.17 2.11 -9.44 -8.28 -15.79 1.52 -13.75 -33.33 -27.01 -14.67 7.21
Cytoplasm 10.02 26.08 5.15 -4.41 -18.07 -18.28 -10.13 -15.80 -1.09 -7.14 7.92 15.27 4.15 -4.04 -12.69
Cytoplasmic Foci 11.87 18.75 16.15 4.89 -6.50 -5.83 3.48 2.65 10.73 -1.49 11.52 18.11 16.82 10.79 -4.53
Eisosomes -8.53 -4.75 -7.94 2.11 3.89 -4.07 -6.06 -2.37 0.92 4.46 -11.42 -8.57 -6.59 1.91 6.06
Endoplasmic Reticulum 2.07 21.43 28.34 21.30 5.26 2.80 15.17 17.11 29.34 7.81 1.17 26.39 32.47 36.41 10.29
Endosome 7.79 15.79 17.94 12.70 2.96 0.85 11.41 8.16 9.59 -0.64 9.19 19.22 18.01 15.98 0.43
Golgi 7.60 7.20 14.07 6.94 5.51 11.55 13.08 12.51 4.36 -1.49 14.49 18.55 18.35 8.00 0.52
Lipid Particles 0.22 2.36 -0.71 -0.83 -2.70 -3.65 -4.11 -3.20 0.35 1.10 0.77 1.31 -0.02 -0.81 -1.36
Mitochondria 0.10 14.16 9.58 5.68 -4.93 -1.15 1.95 1.32 5.23 -2.50 -2.27 7.24 5.42 7.31 -2.34
Mitotic Spindle -1.66 5.17 -2.19 -0.85 -2.91 1.12 2.58 1.79 0.59 -0.45 -1.26 3.40 -1.83 -0.92 -2.60
None 3.12 4.02 3.28 0.44 -7.38 0.14 1.81 -0.08 -0.23 -2.17 3.31 3.76 3.33 0.06 -4.28
Nuclear Periphery -2.27 -11.94 -10.11 -0.17 6.49 1.91 -5.90 -1.01 -4.09 6.44 -3.59 -18.30 -11.47 -1.79 9.16
Nuclear Periphery Foci 2.02 5.56 6.02 2.06 1.41 5.52 6.97 0.91 -0.85 -1.30 4.68 7.25 5.29 0.83 -1.56
Nucleolus 1.58 5.15 2.02 0.26 -3.21 -1.47 0.70 -1.04 0.45 -2.06 1.61 3.46 1.97 0.52 -2.26
Nucleus 0.10 2.32 -6.82 -6.42 -9.81 0.71 0.16 -0.03 -6.00 -1.46 1.03 -0.46 -3.44 -9.23 -6.49
Peroxisomes 0.22 11.17 10.02 8.33 -7.47 -15.50 -7.78 -6.99 13.77 3.26 -4.98 7.01 9.03 16.22 3.93
Vacuole 1.08 -16.89 -18.87 -18.83 7.82 4.19 -9.75 -8.98 -20.14 0.85 5.14 -20.16 -21.23 -28.12 1.82
Vacuole Periphery 8.04 3.00 12.05 3.49 4.27 8.56 9.71 9.09 2.33 -2.98 12.07 14.66 14.39 4.04 -0.31
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages ER (37%), cytoplasm (6%), mixed (56%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Mrpl38

Mrpl38


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mrpl38-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available