Standard name
Human Ortholog
Description Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.06 0.21 0.1 0.13 0.07 0 0 – 0 0 0 0 0.15 0.06 0 0.1 0 0 0.1 0.16 0.1 0.09 0.11 0.11
Bud 0 0.06 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.23 0.24 0.46 0.4 0.66 0.75 0.8 – 0.61 0.62 0.36 0.46 0.17 0.26 0.36 0.21 0.15 0.17 0.06 0 0.12 0.12 0.13 0.12
Endoplasmic Reticulum 0.41 0.34 0.27 0.22 0.11 0.07 0 – 0 0 0 0.05 0.4 0.17 0.11 0.05 0 0.05 0.15 0.18 0.14 0.09 0.1 0.12
Endosome 0.2 0.25 0.17 0.29 0.15 0.14 0.08 – 0.05 0 0 0 0.29 0.52 0.49 0.44 0.57 0.63 0.35 0.29 0.2 0.25 0.22 0.25
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0.07 0 0.07 0.15 0.05 0 0.06 0.07
Mitochondria 0.17 0 0 0 0 0 0.12 – 0.3 0.31 0.67 0.48 0 0 0 0.07 0.06 0 0.14 0.08 0.22 0.19 0.21 0.15
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.09 0 0 0.09 0.05 0 0 – 0 0 0 0 0.17 0.14 0.08 0.17 0.15 0.17 0 0 0 0.05 0 0
Vac/Vac Membrane 0 0.09 0.07 0 0 0 0 – 0 0 0 0 0 0 0 0.11 0.12 0.15 0.05 0 0.08 0.06 0.06 0.05
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 9 37 7 15 11 1 0 – 0 1 1 1 22 11 2 18 7 6 21 37 13 17 21 29
Bud 4 11 0 1 2 0 1 – 2 4 6 4 3 3 0 1 1 0 1 4 0 2 2 6
Bud Neck 0 0 1 0 0 0 0 – 1 4 0 1 0 0 1 1 0 0 3 3 1 5 1 6
Bud Site 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 2 2 1 1 2 0 2 – 1 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0
Cytoplasm 37 41 32 48 109 77 126 – 94 119 81 105 26 50 47 37 24 26 13 9 15 22 25 30
Endoplasmic Reticulum 65 59 19 26 18 7 3 – 4 2 6 11 60 33 14 9 6 8 32 42 18 16 20 31
Endosome 31 43 12 34 24 14 13 – 7 7 6 4 44 100 64 77 89 95 75 69 26 46 43 65
Golgi 0 3 0 0 1 0 0 – 0 1 0 0 2 1 0 9 11 4 14 35 6 6 11 19
Mitochondria 27 4 0 5 1 3 19 – 46 60 149 108 0 1 1 13 10 3 31 19 29 35 40 39
Nucleus 0 0 1 2 1 3 1 – 0 1 2 7 2 1 1 1 0 0 0 0 0 1 0 2
Nuclear Periphery 1 0 0 0 0 0 0 – 0 0 1 1 0 0 0 1 0 0 0 1 0 1 2 1
Nucleolus 0 0 0 1 0 0 0 – 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0
Peroxisomes 2 1 1 0 1 1 1 – 0 0 0 0 1 5 1 0 0 1 7 2 0 5 5 5
SpindlePole 14 5 1 11 8 1 2 – 3 8 3 8 26 27 10 29 23 25 6 2 2 10 6 6
Vac/Vac Membrane 0 15 5 3 6 4 5 – 5 6 6 6 1 7 5 19 19 23 10 7 11 11 11 13
Unique Cell Count 158 174 70 119 165 103 158 153 191 223 226 150 191 131 174 156 150 217 239 131 188 198 263
Labelled Cell Count 192 221 80 147 184 111 173 163 213 261 257 187 239 147 217 190 192 217 239 131 188 198 263


Lipid Particles

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.3 8.2 7.5 7.6 7.3 6.2 5.8 – 4.7 5.1 4.4 4.6 8.3 8.2 7.2 8.5 9.5 8.5 7.4 7.3 8.0
Std Deviation (1e-4) 0.7 1.1 1.2 1.8 1.6 2.3 1.8 – 1.1 1.7 1.6 1.5 1.4 1.7 1.3 1.4 2.0 1.7 1.1 1.2 1.6
Intensity Change (Log2) – – – 0.03 -0.04 -0.26 -0.37 – -0.66 -0.54 -0.77 -0.7 0.16 0.13 -0.06 0.18 0.34 0.19 -0.01 -0.03 0.09


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0.5 -0.9 0 0 – 0 0 0 0 1.0 0 0 0.1 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.7 2.9 3.9 5.1 – 2.2 2.4 -1.4 0.1 -4.5 -3.0 -1.4 -3.8 -4.9 -4.5
Endoplasmic Reticulum -0.8 -3.1 -3.7 -6.0 – 0 -6.9 0 0 1.9 -1.8 -3.0 -4.9 -5.2 -4.6
Endosome 1.8 -0.5 -0.6 -2.0 – 0 -3.7 0 0 1.9 5.1 4.4 4.0 5.6 6.4
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 3.0 – 0 5.3 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 3.3 2.9 0 3.3 3.0 3.3
Vacuole 0 0 0 0 – 0 0 0 0 0 0 0 0.9 1.1 1.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.3255 3.5745 2.8705 2.5065 2.5836 3.3056 2.7665 3.9676 3.6213 3.3332 3.1562 3.5994 3.9006 5.3202 4.4827 4.4032 4.1636 4.5308
Actin 0.0234 0.0021 0.0384 0.029 0.003 0.0342 0.0088 0.0093 0.0097 0.0093 0.0106 0.0047 0.0035 0.0033 0.0033 0.0018 0.001 0.0009
Bud 0.0004 0.0001 0.0007 0.0009 0.0003 0.0002 0.0003 0.0002 0.0004 0.0004 0.0004 0.0001 0.0001 0.0002 0.0001 0.0003 0 0.0001
Bud Neck 0.0023 0.0014 0.0026 0.0016 0.0007 0.0012 0.0009 0.001 0.0046 0.0028 0.0009 0.0008 0.0003 0.0006 0.0007 0.0004 0.0003 0.0004
Bud Periphery 0.0006 0.0001 0.0006 0.001 0.0006 0.0002 0.0005 0.0002 0.0003 0.0005 0.0005 0.0003 0.0001 0.0002 0.0001 0.001 0 0.0001
Bud Site 0.0054 0.0031 0.016 0.0044 0.0005 0.0006 0.0047 0.0095 0.0045 0.0023 0.0013 0.0003 0.0003 0.008 0.0016 0.0002 0.0002 0.0002
Cell Periphery 0.0006 0.0003 0.0005 0.0004 0.0003 0.0003 0.0003 0.0008 0.0004 0.0002 0.0002 0.0002 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001
Cytoplasm 0.0067 0.0767 0.0219 0.0056 0.0023 0.0045 0.0062 0.013 0.0214 0.0069 0.0016 0.0051 0.0063 0.0114 0.0131 0.0375 0.0032 0.0054
Cytoplasmic Foci 0.1634 0.1561 0.179 0.1022 0.0993 0.0972 0.1343 0.1458 0.1555 0.1875 0.1183 0.1222 0.1179 0.1175 0.1346 0.1107 0.1483 0.1058
Eisosomes 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0001 0 0 0 0 0
Endoplasmic Reticulum 0.0142 0.0197 0.008 0.0776 0.0067 0.0243 0.0041 0.0168 0.0127 0.0019 0.0013 0.0089 0.0129 0.0179 0.0083 0.0109 0.0017 0.0117
Endosome 0.1989 0.2562 0.1911 0.3465 0.2639 0.1983 0.2011 0.2085 0.2106 0.2277 0.1823 0.1931 0.2889 0.2603 0.3017 0.3019 0.2803 0.2291
Golgi 0.0998 0.0971 0.1319 0.1263 0.1916 0.1256 0.0918 0.083 0.1057 0.1392 0.1218 0.1096 0.0885 0.1117 0.1411 0.1649 0.1846 0.1024
Lipid Particles 0.4004 0.3238 0.3437 0.2343 0.1768 0.4779 0.4712 0.4609 0.423 0.3217 0.4503 0.5085 0.4446 0.4356 0.3573 0.3129 0.3111 0.5094
Mitochondria 0.0144 0.0026 0.0196 0.0402 0.1326 0.0025 0.0126 0.0134 0.0048 0.0313 0.0528 0.0059 0.0049 0.0031 0.0034 0.0036 0.0017 0.0037
None 0.0062 0.016 0.0011 0.0002 0.0006 0.0002 0.0162 0.0017 0.0086 0.0003 0.0002 0.0012 0.0005 0.0007 0.0002 0.0016 0.0001 0.0003
Nuclear Periphery 0.0063 0.0038 0.0013 0.003 0.0215 0.0086 0.0052 0.0014 0.0019 0.0006 0.001 0.0056 0.0083 0.0076 0.0052 0.0089 0.0005 0.0033
Nucleolus 0.0006 0.0011 0.0001 0.0002 0.0002 0.0001 0.0005 0.0004 0.0004 0.0005 0.0002 0.0001 0.0002 0.0005 0.0001 0.0001 0.0001 0.0002
Nucleus 0.0009 0.0019 0.0002 0.0003 0.0013 0.0002 0.0009 0.0005 0.0006 0.0002 0.0002 0.0002 0.0005 0.0006 0.0007 0.0008 0.0001 0.0003
Peroxisomes 0.0363 0.0254 0.0359 0.01 0.0668 0.0127 0.0258 0.0211 0.0247 0.0598 0.0504 0.0261 0.0125 0.0096 0.0173 0.0143 0.061 0.0174
Punctate Nuclear 0.0056 0.0065 0.0018 0.0007 0.0008 0.0015 0.0085 0.0019 0.0021 0.0018 0.001 0.0019 0.0025 0.0017 0.0039 0.0017 0.0008 0.0021
Vacuole 0.0082 0.0043 0.0044 0.0116 0.0116 0.007 0.0037 0.0096 0.0065 0.0033 0.0025 0.0034 0.0051 0.0073 0.0054 0.0151 0.0035 0.0053
Vacuole Periphery 0.0053 0.0014 0.0013 0.0039 0.0185 0.0028 0.0023 0.0009 0.0015 0.0018 0.0022 0.0016 0.0017 0.0019 0.0015 0.0114 0.0013 0.0017

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 27.3147 21.2748 22.245 27.091 22.7916 21.6234 23.222 28.2119 32.9837 29.0437
Translational Efficiency 1.2277 1.412 1.147 1.2542 1.2645 1.3958 1.3748 1.1087 1.0358 1.1431

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1471 2301 220 916 117 2189 1092 2773 1588 4490 1312 3689

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 712.15 859.14 1175.71 1127.52 847.00 840.42 1168.23 1258.89 722.09 850.01 1169.48 1226.27
Standard Deviation 77.27 119.79 127.14 173.19 93.24 110.42 136.35 168.41 86.10 115.69 134.88 178.85
Intensity Change Log 2 — 0.270712 0.723279 0.662900 — -0.011251 0.463890 0.571718 — 0.124402 0.588176 0.614082

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002376 0.017340 0.106418* 0.070760 0.011262 0.006613 0.060716 0.094766 0.003031 0.012110 0.068380 0.088805
Bud Neck 0.008846 0.001699 0.008166 0.005539 0.003979 0.001867 0.001641 0.003368 0.008487 0.001781 0.002735 0.003907
Bud Site 0.002410 0.006299 0.021683 0.037248 0.005154 0.002493 0.010963 0.019094 0.002612 0.004444 0.012760 0.023601
Cell Periphery 0.000383 0.000122 0.001458 0.002153 0.000981 0.000102 0.000377 0.000875 0.000427 0.000112 0.000558 0.001192
Cytoplasm 0.103642* 0.013565 0.003166 0.024099 0.073057 0.014524 0.011131 0.023800 0.101388* 0.014033 0.009795 0.023874
Cytoplasmic Foci 0.337106* 0.213809* 0.055343 0.189552* 0.237792* 0.247552* 0.161139 0.166486 0.329789* 0.230260* 0.143399 0.172213
Eisosomes 0.001714 0.000439 0.000576 0.001063 0.001440 0.000344 0.000639 0.002182 0.001694 0.000393 0.000628 0.001904
Endoplasmic Reticulum 0.009391 0.005500 0.135338* 0.047387 0.027021 0.005348 0.063839 0.016240 0.010690 0.005426 0.075828 0.023974
Endosome 0.068180 0.129921 0.201699* 0.226036* 0.122553 0.171570 0.180087 0.186169 0.072186 0.150226 0.183711 0.196068
Golgi 0.117623* 0.282778* 0.036244 0.110821* 0.140649* 0.269828* 0.139489* 0.245827* 0.119320* 0.276465* 0.122177* 0.212304*
Lipid Particles 0.244761* 0.277434* 0.369421* 0.162958* 0.286368* 0.217708* 0.317645* 0.182317* 0.247827* 0.248316* 0.326327* 0.177510*
Mitochondria 0.021077 0.011390 0.000101 0.001562 0.003909 0.015006 0.000346 0.006975 0.019813 0.013153 0.000305 0.005631
Mitotic Spindle 0.000952 0.006359 0.005526 0.037240 0.000715 0.008722 0.012966 0.007910 0.000934 0.007511 0.011718 0.015193
None 0.001451 0.000326 0.000005 0.000132 0.000197 0.000198 0.000041 0.000073 0.001359 0.000264 0.000035 0.000088
Nuclear Periphery 0.000916 0.000129 0.000423 0.000511 0.000906 0.000286 0.000233 0.000113 0.000915 0.000206 0.000265 0.000212
Nuclear Periphery Foci 0.001662 0.002631 0.027188 0.011977 0.006470 0.002710 0.015886 0.002185 0.002016 0.002669 0.017781 0.004617
Nucleolus 0.001324 0.000238 0.000008 0.000191 0.000551 0.000173 0.000048 0.000028 0.001267 0.000206 0.000041 0.000069
Nucleus 0.011219 0.000916 0.000123 0.001209 0.006881 0.000551 0.000346 0.000375 0.010900 0.000738 0.000309 0.000582
Peroxisomes 0.046811 0.020879 0.004263 0.010249 0.044375 0.017620 0.005725 0.016011 0.046632 0.019290 0.005480 0.014580
Vacuole 0.015626 0.005993 0.022065 0.055044 0.021728 0.012423 0.015881 0.021978 0.016075 0.009128 0.016918 0.030188
Vacuole Periphery 0.002530 0.002232 0.000787 0.004267 0.004012 0.004362 0.000863 0.003229 0.002639 0.003270 0.000851 0.003487

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -9.25 -7.24 -11.32 -8.49 2.39 0.86 -6.90 -12.80 -22.71* -5.56 -8.71 -13.85 -26.40 -22.89 -3.52
Bud Neck 9.65 0.45 3.19 -5.73 1.74 2.39 2.59 0.51 -3.80 -4.40 9.97 8.04 6.16 -6.41 -3.03
Bud Site -4.00 -4.98 -10.93 -9.39 -3.26 1.57 -2.81 -7.15 -14.39 -4.95 -3.21 -7.95 -17.62 -15.29 -6.56
Cell Periphery 5.59 -2.82 -5.03 -5.83 -1.29 3.10 2.11 0.36 -9.68 -5.85 6.60 -1.61 -6.64 -10.27 -4.99
Cytoplasm 21.28 23.64 14.58 -4.09 -7.12 4.47 4.65 3.68 -5.52 -6.38 21.89 22.28 18.34 -7.28 -8.38
Cytoplasmic Foci 18.60 32.36 18.83 3.87 -15.43 -0.43 4.64 4.41 17.94 -1.08 16.71 27.62 26.65 16.64 -6.06
Eisosomes 7.04 5.88 2.82 -3.78 -2.69 2.07 1.50 -1.32 -11.04 -8.40 7.60 5.81 -0.92 -11.48 -8.63
Endoplasmic Reticulum 3.01 -8.45 -7.93 -8.95 5.72 1.99 -3.24 0.96 -8.22 10.36 3.74 -13.88 -6.72 -12.18 11.01
Endosome -15.25 -11.60 -20.99 -12.35 -1.60 -3.53 -3.98 -4.56 -2.77 -1.04 -21.62 -21.13 -30.03 -11.37 -2.14
Golgi -26.40* 14.23 1.49 25.95 -11.59 -8.03 0.10 -6.49 4.08 -17.34 -30.36* -0.44 -17.45 13.62 -17.02
Lipid Particles -3.70 -6.16 8.42 11.98 10.07 2.48 -1.12 3.81 4.78 14.14 -0.07 -7.85 9.58 12.35 17.23
Mitochondria 5.08 12.80 11.68 9.91 -4.48 -7.06 3.07 -2.20 6.09 -8.50 3.92 12.78 8.69 8.20 -8.97
Mitotic Spindle -7.09 -2.86 -8.56 -7.27 -7.11 -7.83 -6.18 -7.94 0.40 2.26 -9.73 -6.39 -11.02 -5.73 -1.85
None 3.14 4.11 3.69 1.94 -3.69 0.03 1.46 1.19 1.35 -1.87 3.32 4.05 3.89 2.72 -3.45
Nuclear Periphery 3.98 2.27 1.74 -3.57 -0.72 1.32 1.41 1.69 3.01 3.14 3.79 3.40 3.70 -0.39 1.21
Nuclear Periphery Foci -2.48 -5.06 -6.95 -6.24 2.74 1.98 -3.91 2.21 0.71 8.26 -1.86 -9.86 -5.50 -4.04 7.85
Nucleolus 3.14 3.88 3.19 0.16 -3.98 1.24 1.65 1.75 5.19 0.67 3.34 3.84 3.76 3.43 -0.85
Nucleus 13.80 15.24 12.65 -1.64 -4.99 3.28 3.30 3.31 0.64 0.08 14.62 14.98 14.61 0.25 -1.81
Peroxisomes 9.99 18.27 15.13 6.76 -5.60 4.76 6.97 5.11 1.23 -9.17 11.94 18.73 14.40 4.34 -9.98
Vacuole 7.40 -1.98 -10.03 -12.68 -7.01 2.12 1.12 -0.49 -6.75 -3.59 5.40 -0.88 -8.85 -14.89 -7.47
Vacuole Periphery 1.02 6.46 -2.19 -2.52 -4.43 -0.19 1.61 0.39 2.05 -6.86 -1.98 7.91 -2.20 -0.48 -8.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function
Localization
Cell Percentages ER (30%)
Cell Cycle Regulation No
Subcompartmental Group ER-2

Coy1

Coy1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Coy1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available