Standard name
Human Ortholog
Description Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.94 0.96 0.99 0.99 0.98 0.96 0.93 0.92 0.87 0.85 0.75 0.86 0.99 0.99 0.99 0.95 0.89 0.95 0.73 0.83 0.7 0.69 0.69 0.73
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.05 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.09 0.05 0 0 0 0.06 0.07 0.1 0.24 0.28 0.33 0.21 0 0 0 0 0 0 0.12 0.07 0.17 0.18 0.19 0.11
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 2 1 1 3 3
Bud 0 2 0 0 1 0 4 1 2 7 8 2 1 0 2 0 0 0 0 2 0 1 2 5
Bud Neck 0 3 6 5 12 7 21 13 10 9 5 15 0 0 0 2 2 0 1 0 0 0 3 7
Bud Site 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 7 7 2 1 4 0 2 1 1 2 1 2 0 3 2 1 1 2 6 1 7 4
Cytoplasm 134 218 217 268 294 310 400 345 311 352 208 291 356 371 385 158 143 106 111 177 136 94 230 271
Endoplasmic Reticulum 3 3 0 0 0 0 1 0 0 0 0 0 1 1 0 19 8 6 1 0 1 0 2 5
Endosome 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 3 1 2 3 1 1 0 1 1
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 1 2 0 0 0 0 0
Mitochondria 13 12 0 1 3 18 28 37 84 117 92 71 3 3 0 3 5 3 18 14 33 24 63 42
Nucleus 0 0 1 1 0 1 1 1 2 0 3 2 0 1 0 1 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 3 0 0 0 0 1 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 2 6 6 11 4 7 6 11 0 0 1 1 2 1 1 1 1 0 3 2
Vac/Vac Membrane 0 0 0 0 1 1 0 0 1 2 1 1 1 0 1 1 4 3 3 4 1 7 10 23
Unique Cell Count 143 226 220 271 300 322 429 375 356 415 277 340 359 373 387 166 160 112 152 214 195 138 335 372
Labelled Cell Count 150 239 232 283 315 344 465 409 416 496 328 395 364 378 390 194 169 124 152 214 195 138 335 372


Ambiguous

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.5 2.9 4.3 4.1 4.5 3.4 3.7 3.8 3.0 3.0 2.9 3.3 3.7 3.7 3.7 5.1 5.5 5.4 3.4 3.4 3.9
Std Deviation (1e-4) 0.7 0.5 1.1 1.7 1.7 1.5 1.6 1.3 1.1 1.1 1.4 1.0 1.1 0.9 1.0 1.2 1.4 1.6 1.0 1.0 1.6
Intensity Change (Log2) – – – -0.07 0.06 -0.33 -0.22 -0.17 -0.52 -0.53 -0.55 -0.37 -0.22 -0.2 -0.22 0.25 0.37 0.33 -0.35 -0.32 -0.14


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.8117 -1.5839 -1.3033 -1.7877 -1.0889 -1.5057 -0.7762 -0.959 -1.0055 -1.1806 -0.7373 -0.9556 -2.0994 -1.8156 -1.782 -2.1542 -1.5063 -1.8582
Actin 0.0871 0.0019 0.0366 0.0507 0.0919 0.0087 0.0257 0.0015 0.001 0.0007 0.0087 0.0014 0.0133 0 0.0288 0 0.0652 0.0007
Bud 0.0023 0.0044 0.0006 0.0002 0.0006 0.0005 0.0007 0.0016 0.0007 0.0001 0.0002 0.0003 0.0001 0 0.0033 0 0.0017 0.0007
Bud Neck 0.0065 0.0002 0.0094 0.0009 0.0042 0.0034 0.0025 0.0002 0.0002 0.0001 0.0001 0.0007 0.0004 0 0.0011 0 0.0004 0.0249
Bud Periphery 0.0041 0.0041 0.0013 0.0005 0.0009 0.0024 0.001 0.0017 0.0012 0.0001 0.0004 0.0007 0.0002 0 0.0061 0 0.0044 0.0025
Bud Site 0.0058 0.0111 0.0045 0.0008 0.0029 0.0011 0.0142 0.0048 0.0007 0.0002 0.0003 0.0002 0.003 0 0.0228 0 0.0012 0.0005
Cell Periphery 0.0004 0.0003 0.0003 0.0001 0.0004 0.0003 0.0003 0.0005 0.0047 0 0.0001 0.0001 0.0001 0 0.0007 0 0.0002 0.0007
Cytoplasm 0.015 0.0159 0.0094 0.01 0.0164 0.0359 0.031 0.0483 0.047 0.0612 0.0366 0.0963 0.0141 0.0578 0.0333 0.0143 0.012 0.0825
Cytoplasmic Foci 0.0448 0.0117 0.0293 0.0063 0.0074 0.0137 0.0152 0.008 0.0099 0.0369 0.0078 0.0132 0.0034 0.0139 0.0138 0.0008 0.0025 0.0012
Eisosomes 0.0031 0.0012 0.0005 0.001 0.002 0.0007 0.0009 0.0002 0.0002 0.0001 0.0003 0.0001 0.0005 0.0001 0.0003 0 0.0004 0.0001
Endoplasmic Reticulum 0.0041 0.0006 0.0028 0.0005 0.0062 0.0015 0.0039 0.0009 0.0013 0.0003 0.0037 0.0016 0.0005 0.0002 0.0004 0.0001 0.0015 0.0004
Endosome 0.0235 0.0002 0.0093 0.0045 0.019 0.0044 0.0203 0.0036 0.0188 0.0136 0.0435 0.0081 0.0009 0.0047 0.0032 0 0.0095 0.0001
Golgi 0.007 0.0001 0.0044 0.0065 0.0061 0.0014 0.0051 0.001 0.0014 0.0094 0.0201 0.0038 0.0006 0.0012 0.0008 0 0.013 0
Lipid Particles 0.0152 0.0014 0.0112 0.0235 0.0154 0.0032 0.0136 0.0013 0.0009 0.007 0.0322 0.0064 0.0007 0.0019 0.0016 0 0.0024 0
Mitochondria 0.0083 0.0013 0.0052 0.0095 0.0535 0.0005 0.0361 0.0011 0.0015 0.0021 0.0204 0.0124 0.0002 0 0.0005 0 0.0051 0.0001
None 0.7029 0.9424 0.8166 0.8539 0.6838 0.907 0.7841 0.9148 0.8945 0.8504 0.8159 0.8467 0.9603 0.9165 0.8751 0.9841 0.8763 0.8841
Nuclear Periphery 0.0189 0.0003 0.0136 0.0008 0.0271 0.0034 0.0144 0.0003 0.0019 0.0002 0.0026 0.0007 0.0003 0.0001 0.0005 0.0001 0.0013 0.0001
Nucleolus 0.0021 0.0004 0.0005 0.0003 0.0026 0.0011 0.0011 0.0003 0.0002 0.0002 0.0005 0.0001 0.0002 0 0.0003 0 0.0001 0.0001
Nucleus 0.0066 0.0007 0.0027 0.0004 0.0318 0.0022 0.0052 0.0007 0.0013 0.0004 0.0005 0.0004 0.0002 0.0001 0.0004 0.0001 0.0002 0.0008
Peroxisomes 0.0232 0.0006 0.0266 0.0268 0.0129 0.0006 0.0155 0.0073 0.0014 0.0137 0.0017 0.003 0.0003 0.0031 0.0021 0 0.0011 0
Punctate Nuclear 0.0166 0.001 0.0126 0.0021 0.0099 0.007 0.0056 0.0006 0.0012 0.0029 0.0007 0.0006 0.0005 0.0001 0.0042 0.0001 0.0004 0.0001
Vacuole 0.0013 0.0003 0.0008 0.0003 0.0029 0.0006 0.0019 0.0014 0.0071 0.0004 0.0017 0.0029 0.0002 0.0001 0.0004 0 0.0005 0.0003
Vacuole Periphery 0.0011 0 0.0017 0.0004 0.0022 0.0002 0.0017 0.0001 0.0028 0.0002 0.002 0.0004 0 0 0.0001 0 0.0005 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression – – – – – – – – – –
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression –
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1654 847 502 1017 1622 1816 1150 1438 3276 2663 1652 2455

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 616.45 675.42 857.22 749.86 648.60 716.78 766.42 762.92 632.37 703.62 794.01 757.51
Standard Deviation 59.59 88.26 86.27 103.45 67.32 91.32 81.68 118.96 65.54 92.38 93.00 112.98
Intensity Change Log 2 — 0.131801 0.475682 0.282637 — 0.144201 0.240806 0.234203 — 0.138172 0.360037 0.258008

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000087 0.000327 0.000587 0.000260 0.000207 0.000250 0.000190 0.000186 0.000146 0.000274 0.000311 0.000217
Bud Neck 0.034616 0.045641 0.002499 0.004717 0.027243 0.049794 0.002726 0.005697 0.030966 0.048473 0.002657 0.005291
Bud Site 0.004855 0.012170 0.002601 0.014966 0.004190 0.016004 0.003447 0.028068 0.004526 0.014784 0.003190 0.022640
Cell Periphery 0.000257 0.000163 0.000129 0.000306 0.000183 0.000199 0.000216 0.001754 0.000220 0.000188 0.000189 0.001154
Cytoplasm 0.446900* 0.313158* 0.134042* 0.457609* 0.391973* 0.365956* 0.383542* 0.464384* 0.419705* 0.349163* 0.307726* 0.461577*
Cytoplasmic Foci 0.247560* 0.327201* 0.008601 0.034655 0.313149* 0.267006* 0.021483 0.019783 0.280034* 0.286151* 0.017569 0.025944
Eisosomes 0.000372 0.000206 0.000066 0.000090 0.000271 0.000212 0.000069 0.000043 0.000322 0.000210 0.000068 0.000062
Endoplasmic Reticulum 0.001035 0.000427 0.005442 0.000771 0.001509 0.000532 0.000544 0.001520 0.001270 0.000498 0.002032 0.001210
Endosome 0.015040 0.034291 0.002518 0.002972 0.015921 0.027790 0.001300 0.002411 0.015476 0.029858 0.001671 0.002644
Golgi 0.003816 0.007936 0.000080 0.000567 0.005120 0.006709 0.000120 0.001181 0.004462 0.007099 0.000108 0.000927
Lipid Particles 0.015925 0.014613 0.002838 0.001961 0.017835 0.011440 0.001208 0.001119 0.016871 0.012449 0.001703 0.001468
Mitochondria 0.008149 0.025894 0.000509 0.000699 0.011892 0.015827 0.000971 0.001990 0.010002 0.019029 0.000831 0.001455
Mitotic Spindle 0.000458 0.007315 0.004131 0.004837 0.001761 0.006923 0.002179 0.012418 0.001103 0.007048 0.002772 0.009277
None 0.003581 0.004169 0.008659 0.020151 0.003139 0.002272 0.010832 0.005036 0.003362 0.002876 0.010172 0.011297
Nuclear Periphery 0.000532 0.000468 0.002519 0.000808 0.000677 0.000717 0.000895 0.001391 0.000604 0.000638 0.001388 0.001150
Nuclear Periphery Foci 0.000189 0.000393 0.000966 0.000509 0.000313 0.000300 0.000200 0.000540 0.000250 0.000330 0.000433 0.000527
Nucleolus 0.001384 0.002498 0.001306 0.000682 0.001318 0.002011 0.000818 0.000429 0.001352 0.002166 0.000967 0.000534
Nucleus 0.154907* 0.104632 0.774691* 0.391199* 0.152218* 0.121404 0.538540* 0.387198* 0.153576* 0.116069 0.610300* 0.388855*
Peroxisomes 0.006407 0.033170 0.002755 0.000989 0.011756 0.019228 0.001308 0.000397 0.009056 0.023662 0.001748 0.000642
Vacuole 0.052564 0.062657 0.044851 0.061074 0.038095 0.082740 0.029261 0.064017 0.045400 0.076352 0.033998 0.062798
Vacuole Periphery 0.001366 0.002672 0.000208 0.000179 0.001230 0.002688 0.000149 0.000439 0.001299 0.002683 0.000167 0.000332

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -6.21 -3.53 -2.92 0.99 2.19 -0.82 0.26 -0.11 1.07 -0.34 -3.94 -2.17 -2.58 1.21 1.03
Bud Neck -2.62 14.48 13.68 12.11 -1.10 -7.24 12.44 11.14 17.82 -3.79 -7.06 19.02 17.61 21.57 -3.68
Bud Site -5.36 2.50 -2.91 0.14 -3.73 -7.26 0.83 -5.25 -0.51 -5.35 -8.64 1.81 -5.95 -0.17 -6.40
Cell Periphery 5.42 7.82 1.15 -2.34 -3.13 -0.58 -0.51 -1.02 -1.00 -1.00 2.21 2.70 -0.97 -1.05 -1.07
Cytoplasm 12.49 34.53 4.44 -7.11 -25.01 2.86 3.33 1.42 -1.25 -1.90 10.31 16.85 4.55 -5.02 -11.82
Cytoplasmic Foci -8.43 46.27 40.60 36.98 -9.37 5.82 48.82 49.86 45.40 2.04 -0.97 65.29 64.08 57.58 -3.27
Eisosomes 6.33 11.43 11.65 11.13 0.72 3.92 14.72 17.67 15.99 2.22 7.30 17.03 18.39 18.77 1.68
Endoplasmic Reticulum 3.36 -13.59 -3.21 -10.83 12.81 3.00 2.08 -2.68 -13.71 -11.23 4.16 -7.17 -4.24 -17.12 4.84
Endosome -7.82 12.78 12.42 13.58 1.53 -6.87 13.66 12.71 18.66 -3.23 -10.50 19.43 18.09 22.91 -1.22
Golgi -3.30 5.67 5.02 7.35 -1.39 -1.85 9.49 6.93 8.06 -1.30 -3.70 10.30 8.14 10.99 -1.69
Lipid Particles 0.61 11.38 13.12 7.00 4.61 4.55 14.06 14.08 13.08 0.11 3.96 18.72 19.34 13.87 3.27
Mitochondria -5.48 6.32 6.12 8.54 -0.42 -1.99 7.34 6.95 10.73 -0.58 -5.58 9.38 9.09 13.77 -0.54
Mitotic Spindle -3.54 -1.78 -3.76 0.13 -1.36 -3.41 -0.66 -4.53 -1.28 -3.99 -5.15 -1.98 -6.07 -0.90 -4.02
None -0.49 -1.03 -4.78 -4.27 -2.76 1.52 -3.89 -1.58 -5.02 3.38 1.08 -3.88 -4.99 -5.72 0.04
Nuclear Periphery 0.34 -15.11 -6.42 -10.67 12.14 -0.28 -4.98 -12.41 -7.92 -9.21 -0.35 -12.40 -13.23 -9.72 -1.35
Nuclear Periphery Foci -2.21 -9.63 -4.83 -2.48 3.37 0.08 1.27 -5.26 -4.56 -6.14 -1.48 -7.32 -7.36 -5.10 -2.42
Nucleolus -3.66 0.93 5.30 7.02 4.32 -1.96 2.91 4.76 6.33 2.77 -3.47 3.42 7.12 8.77 4.36
Nucleus 7.45 -52.76 -26.68 -29.50 25.59 5.57 -41.98 -30.88 -35.37 12.15 8.98 -59.63 -40.96 -46.06 22.34
Peroxisomes -10.04 3.51 9.74 12.49 0.77 -4.78 8.82 11.25 16.15 1.17 -11.24 9.43 14.73 20.04 1.32
Vacuole -3.05 -3.77 -10.85 -8.27 -5.65 -13.14 -2.17 -18.18 -9.37 -15.59 -11.95 -2.98 -20.65 -11.91 -16.36
Vacuole Periphery -4.21 8.68 9.30 9.16 2.80 -5.63 10.38 7.95 9.60 -1.61 -6.78 13.05 11.73 12.87 -1.08
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein required for fatty acid uptake; protein abundance increases in cortical patches in response to oleate exposure; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; FAT3 has a paralog, YLR413W, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (10%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Fat3

Fat3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fat3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available