Standard name
Human Ortholog
Description Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box RNA helicase Prp43p, that is involved in spliceosome disassembly
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.07 0.05 0 0.11 0.06 0.05 0.05 0.06 0.05 0 0 0.11 0.2 0.17 0.15 0.16 0.14 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.05 0.06 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.3 0 0.05 0.06 0.07 0.35 0.46 0.26 0.58 0.44 0.65 0.37 0 0 0 0.06 0 0.07 0 0 0 0 0 0
Nucleus 0.86 0.83 0.88 0.88 0.8 0.79 0.77 0.83 0.77 0.82 0.71 0.83 0.86 0.77 0.78 0.7 0.63 0.69 0.82 0.79 0.79 0.68 0.6 0.57
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.15 0 0 0.08 0 0 0 0 0 0 0 0 0.05 0.06 0.13 0.17 0.15 0.12 0.11 0.13 0.16 0.22 0.23
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2
Bud 0 0 0 0 0 1 2 6 4 7 6 1 0 1 0 0 0 0 3 4 0 2 3 8
Bud Neck 1 0 3 2 0 1 1 0 0 1 0 1 1 1 0 0 0 0 0 1 0 0 2 1
Bud Site 0 0 0 1 0 8 7 5 10 16 12 6 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0
Cytoplasm 17 21 7 8 33 22 24 22 26 17 14 15 28 68 47 35 58 31 7 5 1 6 14 7
Endoplasmic Reticulum 0 2 1 0 0 0 0 2 0 0 0 0 2 2 2 21 17 13 0 0 0 0 0 1
Endosome 0 0 1 1 5 2 1 0 1 1 0 0 1 0 3 3 8 2 3 1 1 0 2 1
Golgi 1 1 0 1 0 0 0 0 0 0 0 0 0 0 0 1 3 3 0 3 1 0 1 1
Mitochondria 141 13 7 12 22 122 232 105 265 151 232 129 5 0 1 13 15 16 3 6 3 2 12 12
Nucleus 407 244 128 163 248 277 383 331 352 282 256 289 214 259 222 161 226 159 401 244 136 104 201 175
Nuclear Periphery 0 0 1 0 0 1 2 0 5 3 2 0 0 0 0 1 0 0 0 0 0 0 0 1
Nucleolus 0 0 1 0 0 0 1 1 1 3 2 1 0 0 1 0 1 0 0 1 0 1 7 6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 4 1 4 2 3 3 3 2 6 2 2 7 3 3 0 10 0 2 5 10 8
Vac/Vac Membrane 12 43 5 6 25 13 14 8 9 4 7 7 3 16 16 30 61 34 57 34 21 23 72 70
Unique Cell Count 476 295 146 186 311 352 499 401 458 343 359 349 249 338 283 230 358 229 493 308 174 153 337 306
Labelled Cell Count 579 324 154 199 334 451 669 483 676 489 533 455 256 349 299 269 392 258 493 308 174 153 337 306


Cytoplasm, Endoplasmic Reticulum, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 5.4 5.3 5.1 5.1 4.3 4.1 4.8 3.9 4.3 3.8 4.4 5.3 5.6 5.7 6.9 7.1 6.7 5.2 5.7 6.4
Std Deviation (1e-4) 0.5 0.9 0.9 1.2 1.4 1.3 1.0 1.2 1.0 1.4 0.9 1.1 0.9 0.9 0.9 1.8 2.0 1.8 1.1 1.4 1.7
Intensity Change (Log2) – – – -0.06 -0.05 -0.3 -0.37 -0.16 -0.44 -0.3 -0.48 -0.27 -0.0 0.07 0.11 0.37 0.42 0.32 -0.05 0.09 0.27

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.2 2.1 0.6 0 0.3 0.4 0.1 -0.5 -0.2 2.2 4.3 3.5 3.1 3.5 2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 3.4 2.2 2.5
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.6 0.9 0 0 0 0 0 0 0 0 0 0 0.4 -0.3 0.9
Nucleus 0 -2.1 -2.3 -2.9 -1.4 -2.8 -1.5 -3.9 -1.4 -0.5 -2.8 -2.3 -4.0 -5.5 -4.1
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 1.9 0.1 0 0 0 0 0 0 0 0.6 1.0 3.1 4.1 3.5

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.3713 -0.0391 0.1858 -0.1287 0.208 -0.1821 -0.5046 0.4231 0.0482 -0.1011 -0.49 0.0601 -0.1085 0.0749 -0.0726 0.0215 0.1315 -0.0048
Actin 0.0176 0.0013 0.0118 0.0096 0.0205 0.0003 0.0017 0.0001 0.0002 0.0001 0.0004 0.0002 0.0014 0.0001 0 0 0.0003 0.0001
Bud 0.0054 0.0025 0.002 0.0003 0.0018 0.0001 0.0002 0 0 0.0001 0 0.0001 0.0006 0.0001 0 0 0 0.0007
Bud Neck 0.0095 0.0005 0.0043 0.0022 0.0015 0.0017 0.0008 0.0003 0.0002 0.0009 0.0003 0.0015 0.0005 0.0002 0.0001 0.0002 0.0021 0.0015
Bud Periphery 0.0027 0.0005 0.0031 0.0007 0.0027 0.0001 0.0004 0 0 0.0001 0 0.0001 0.0003 0 0 0 0 0.0002
Bud Site 0.0056 0.0024 0.0094 0.0024 0.0059 0.0002 0.0004 0.0002 0.0001 0.0002 0 0 0.0003 0.0003 0 0 0.0002 0.0005
Cell Periphery 0.001 0.0001 0.0002 0.0001 0.0002 0 0 0 0 0.0001 0 0 0 0 0 0 0 0
Cytoplasm 0.0356 0.0606 0.0292 0.0414 0.0047 0.0102 0.0201 0.0341 0.0217 0.0461 0.0073 0.0142 0.0152 0.0408 0.0074 0.0068 0.0061 0.0105
Cytoplasmic Foci 0.0229 0.0048 0.0063 0.0135 0.02 0.0011 0.0012 0.0003 0.0012 0.0022 0.0008 0.0047 0.0021 0.0014 0.0002 0.0001 0.0007 0.0058
Eisosomes 0.0005 0.0001 0.0001 0.0004 0.0002 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0068 0.0022 0.0014 0.0013 0.0026 0.0006 0.0005 0.0008 0.0007 0.0014 0.0001 0.0004 0.0006 0.0015 0.0001 0.0001 0.0003 0.0002
Endosome 0.0414 0.0046 0.0067 0.0418 0.054 0.0034 0.0039 0.0004 0.0013 0.005 0.0005 0.0007 0.0026 0.0017 0.0002 0.0001 0.0008 0.0003
Golgi 0.0084 0.0006 0.0041 0.0063 0.0267 0.0011 0.0013 0 0.0002 0.0001 0 0 0.0003 0 0 0 0 0
Lipid Particles 0.0288 0.0016 0.0184 0.0181 0.0324 0.0031 0.0018 0 0.0032 0.0003 0.0001 0.0001 0.0007 0.0003 0 0 0.0001 0.0001
Mitochondria 0.0188 0.0025 0.0069 0.0259 0.0447 0.0015 0.0012 0.0002 0.0004 0.0007 0.0004 0.0003 0.0044 0.0003 0.0001 0.0002 0.0004 0.0012
None 0.0868 0.0882 0.0958 0.0849 0.0374 0.0441 0.051 0.0551 0.0377 0.0702 0.0424 0.0357 0.0264 0.0704 0.0183 0.0104 0.055 0.0149
Nuclear Periphery 0.0333 0.0293 0.0275 0.0123 0.046 0.0118 0.0079 0.0146 0.0095 0.0101 0.0111 0.0085 0.0117 0.0167 0.006 0.0069 0.0208 0.0061
Nucleolus 0.0164 0.0078 0.0129 0.0086 0.0088 0.0147 0.0058 0.0049 0.0039 0.0041 0.0062 0.0072 0.0053 0.0052 0.0035 0.0042 0.0208 0.0094
Nucleus 0.5811 0.7247 0.6961 0.6751 0.627 0.8476 0.8869 0.8747 0.8917 0.8349 0.9018 0.8679 0.9134 0.8277 0.9439 0.9467 0.8274 0.9048
Peroxisomes 0.0138 0.003 0.0078 0.0088 0.0363 0.0005 0.001 0 0.0011 0.0001 0.0003 0 0.0003 0 0 0 0.0001 0
Punctate Nuclear 0.0523 0.0601 0.0512 0.0435 0.019 0.0566 0.0129 0.0137 0.0264 0.0146 0.0279 0.0579 0.0125 0.0316 0.0198 0.0242 0.0641 0.0432
Vacuole 0.0087 0.002 0.0035 0.002 0.0043 0.0009 0.0008 0.0004 0.0004 0.0078 0.0001 0.0003 0.0007 0.0013 0.0001 0.0001 0.0004 0.0003
Vacuole Periphery 0.0028 0.0006 0.001 0.001 0.0031 0.0004 0.0003 0.0001 0.0001 0.0009 0.0002 0.0002 0.0006 0.0002 0 0 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 11.9564 10.1793 15.8623 15.55 19.9311 11.3807 14.9238 18.7558 15.5921 16.4667
Translational Efficiency 1.0907 1.1715 0.6159 0.6461 0.6184 1.2674 0.9223 0.5434 0.6814 0.759

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
107 1086 388 1274 1456 1720 503 1453 1563 2806 891 2727

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 714.66 720.52 884.66 798.99 671.35 749.41 920.93 888.38 674.31 738.23 905.14 846.62
Standard Deviation 83.47 102.66 98.41 127.22 78.77 96.69 109.49 112.17 79.85 100.04 106.34 127.50
Intensity Change Log 2 — 0.011781 0.307866 0.160920 — 0.158690 0.456026 0.404112 — 0.084810 0.381533 0.283839

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000192 0.000290 0.000462 0.000811 0.000054 0.000303 0.000533 0.000433 0.000064 0.000298 0.000502 0.000609
Bud Neck 0.007244 0.004550 0.005158 0.009807 0.001576 0.012573 0.003020 0.012955 0.001964 0.009468 0.003951 0.011485
Bud Site 0.001003 0.002719 0.001237 0.007872 0.001005 0.003882 0.001225 0.003864 0.001005 0.003432 0.001230 0.005737
Cell Periphery 0.000141 0.000138 0.000069 0.000214 0.000118 0.000173 0.000087 0.000110 0.000120 0.000159 0.000079 0.000159
Cytoplasm 0.111411 0.063829 0.010518 0.051610 0.058918 0.082874 0.016358 0.025107 0.062511 0.075503 0.013815 0.037488
Cytoplasmic Foci 0.034765 0.010144 0.000193 0.001211 0.008187 0.012200 0.000602 0.000936 0.010006 0.011404 0.000424 0.001065
Eisosomes 0.000061 0.000028 0.000026 0.000025 0.000018 0.000030 0.000035 0.000021 0.000021 0.000029 0.000031 0.000023
Endoplasmic Reticulum 0.001910 0.003692 0.005903 0.008053 0.001193 0.003992 0.006411 0.006757 0.001242 0.003876 0.006190 0.007362
Endosome 0.001115 0.000985 0.000305 0.001432 0.000418 0.002580 0.000561 0.001648 0.000466 0.001963 0.000449 0.001547
Golgi 0.000892 0.000441 0.000038 0.001584 0.000112 0.001059 0.000053 0.000517 0.000166 0.000820 0.000046 0.001016
Lipid Particles 0.006323 0.001638 0.000309 0.000409 0.001530 0.003146 0.000606 0.000250 0.001858 0.002563 0.000476 0.000324
Mitochondria 0.002773 0.002428 0.000626 0.002212 0.002917 0.008479 0.000930 0.003785 0.002907 0.006137 0.000798 0.003050
Mitotic Spindle 0.001662 0.002496 0.000459 0.010077 0.000689 0.007165 0.000697 0.017725 0.000755 0.005358 0.000593 0.014152
None 0.012786 0.012785 0.002230 0.009340 0.007644 0.006198 0.009459 0.003478 0.007996 0.008748 0.006311 0.006216
Nuclear Periphery 0.000733 0.001045 0.000749 0.001678 0.001033 0.003219 0.000862 0.002074 0.001012 0.002377 0.000813 0.001889
Nuclear Periphery Foci 0.000290 0.000670 0.000123 0.000857 0.000211 0.000553 0.000356 0.000560 0.000216 0.000598 0.000254 0.000699
Nucleolus 0.005134 0.006405 0.001664 0.001946 0.002808 0.004744 0.002789 0.001079 0.002967 0.005386 0.002299 0.001484
Nucleus 0.798960 0.879146 0.966036 0.878323 0.909074 0.833730 0.946555 0.906896 0.901536 0.851308 0.955039 0.893547
Peroxisomes 0.007930 0.001776 0.000096 0.000251 0.000827 0.004319 0.000249 0.000158 0.001313 0.003335 0.000182 0.000201
Vacuole 0.004480 0.004375 0.003724 0.011621 0.001486 0.008165 0.008500 0.010037 0.001691 0.006698 0.006420 0.010777
Vacuole Periphery 0.000194 0.000420 0.000074 0.000668 0.000183 0.000616 0.000114 0.001610 0.000184 0.000540 0.000097 0.001170

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 0.29 -1.41 -2.15 -5.80 -1.38 -4.79 -9.87 -11.43 -4.41 1.24 -5.88 -11.31 -12.87 -7.11 -0.31
Bud Neck 0.56 -0.17 -1.62 -6.76 -3.69 -8.93 -6.13 -12.63 -2.00 -9.06 -8.79 -6.16 -14.75 -4.80 -8.83
Bud Site -1.24 -1.04 -4.70 -3.24 -2.62 -3.17 -0.79 -3.72 -0.58 -3.84 -3.03 -1.35 -5.51 -2.93 -4.19
Cell Periphery 0.61 2.62 -0.99 -2.23 -5.24 -2.41 1.41 1.36 3.64 -0.02 -2.21 2.12 -1.11 1.45 -4.07
Cytoplasm 2.53 5.54 3.58 3.67 -9.52 -5.03 10.87 9.32 14.38 -3.39 -3.14 13.60 7.67 12.78 -9.13
Cytoplasmic Foci 2.57 3.77 3.69 6.50 -2.81 -2.77 7.03 7.28 10.49 0.78 -1.28 8.06 7.88 12.13 -1.05
Eisosomes 3.10 2.69 2.74 -1.94 -0.09 -5.88 -7.43 -6.91 0.66 4.22 -4.58 -6.67 -6.03 -0.64 3.30
Endoplasmic Reticulum -3.56 -7.68 -12.83 -12.05 -3.36 -8.48 -13.02 -16.89 -8.40 0.38 -11.31 -16.69 -24.97 -13.72 -1.75
Endosome 0.18 1.60 -0.11 -0.58 -4.17 -5.41 -2.75 -2.00 3.17 -1.06 -5.90 -1.23 -3.32 2.90 -2.85
Golgi 0.64 1.25 0.17 -0.60 -1.47 -2.98 1.95 -1.20 2.46 -1.79 -3.03 2.04 -1.30 0.85 -1.79
Lipid Particles 2.85 3.63 3.59 6.95 -0.93 -3.19 3.48 5.27 6.29 3.82 -1.85 5.30 6.10 7.77 2.45
Mitochondria 0.58 1.86 0.80 0.54 -5.26 -3.78 1.84 0.07 4.57 -2.72 -2.76 2.09 0.38 4.74 -4.25
Mitotic Spindle 0.26 0.95 -3.40 -4.46 -5.27 -4.37 -0.52 -5.62 -2.56 -5.49 -4.44 -0.29 -7.68 -4.56 -7.61
None -0.07 1.76 0.93 3.36 -5.71 1.08 0.30 3.41 2.55 1.56 -0.62 1.95 2.33 3.85 -0.33
Nuclear Periphery -2.63 -1.49 -10.19 -9.50 -9.28 -7.24 -1.20 -10.69 -0.43 -10.25 -7.07 -0.56 -13.65 -2.69 -13.68
Nuclear Periphery Foci -1.19 1.35 -1.91 -0.82 -3.64 -2.18 -2.88 -2.48 0.00 -0.67 -3.13 -1.66 -3.95 -0.67 -3.11
Nucleolus -0.55 1.82 1.73 4.85 -0.49 -2.77 1.05 3.90 6.61 3.38 -3.68 2.13 3.58 7.92 2.20
Nucleus -3.10 -6.18 -2.80 0.96 12.09 10.17 -4.30 2.38 -7.94 6.45 8.02 -7.79 3.29 -5.52 12.71
Peroxisomes 1.55 1.94 1.92 4.62 -2.24 -4.99 2.89 3.46 6.32 1.33 -3.37 3.26 3.30 7.51 0.25
Vacuole -0.20 -0.96 -7.99 -8.22 -6.43 -8.91 -6.04 -10.38 -6.45 -2.60 -9.09 -6.60 -14.48 -9.94 -5.57
Vacuole Periphery -3.18 2.89 -1.45 -0.11 -2.16 -4.30 1.19 -1.39 -0.21 -1.57 -4.78 1.65 -1.83 -0.16 -2.25
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box RNA helicase Prp43p, that is involved in spliceosome disassembly
Localization
Cell Percentages nucleus (94%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Ntr2

Ntr2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ntr2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available