Standard name
Human Ortholog
Description Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BCH2 has a paralog, CHS6, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0.13 0 0.05 0 0 – 0 0 0 0 0 0 0 0.08 0 0 0 0.06 0 0.05 0.07 0.11
Bud 0.06 0.05 0.09 0.08 0.11 0.07 0.08 – 0.14 0.08 0.06 0.11 0.08 0.06 0 0.05 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0.05 0.05 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0.07 0.06 0.08 0 0.07 – 0 0 0 0 0 0.06 0 0.15 0.1 0.19 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.05 0 0 0 0 0 – 0 0 0 0 0 0 0 0.05 0 0.06 0 0 0 0 0 0
Endosome 0.11 0.1 0.16 0.13 0.14 0.08 0.06 – 0 0 0 0 0.06 0.22 0.24 0.25 0.37 0.31 0.28 0.23 0.31 0.21 0.2 0.21
Golgi 0.09 0.07 0.05 0 0 0 0 – 0 0 0 0 0 0.06 0 0.08 0.08 0 0.38 0.31 0.15 0.27 0.27 0.27
Mitochondria 0.83 0.83 0.41 0.62 0.45 0.73 0.69 – 0.88 0.87 0.9 0.81 0.79 0.55 0.61 0.16 0.17 0.15 0.09 0.2 0.22 0.21 0.18 0.11
Nucleus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0.07 0.11 0.15 0.1 0.12 0.08 – 0.05 0.05 0 0.06 0.11 0.2 0.22 0 0 0 0.18 0.11 0.22 0.19 0.23 0.23
SpindlePole 0 0 0.27 0.15 0.27 0.18 0.2 – 0.1 0.14 0.12 0.22 0 0.07 0.05 0.32 0.34 0.3 0 0 0 0 0 0
Vac/Vac Membrane 0 0.07 0.05 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0.09 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 7 10 29 4 14 3 13 – 6 5 0 7 8 1 2 17 5 2 9 22 11 13 20 33
Bud 12 15 20 15 27 24 32 – 60 37 17 29 23 16 13 11 5 7 1 4 0 0 1 3
Bud Neck 0 0 5 0 1 1 3 – 1 1 3 0 0 0 1 2 1 0 0 0 0 0 0 1
Bud Site 0 0 0 1 1 3 4 – 15 16 15 13 1 0 0 2 1 0 – – – – – –
Cell Periphery 0 2 1 1 0 1 2 – 0 0 0 0 2 2 1 1 1 1 0 0 0 0 0 0
Cytoplasm 3 7 15 11 21 14 26 – 8 13 12 8 13 16 14 32 16 32 0 0 0 0 1 0
Endoplasmic Reticulum 7 15 6 2 5 4 6 – 4 2 2 2 9 5 3 10 6 10 1 0 1 4 3 4
Endosome 22 31 34 25 37 26 23 – 7 1 0 7 19 62 83 51 57 52 63 85 98 53 62 64
Golgi 19 21 11 8 2 0 0 – 0 0 0 1 11 18 8 16 13 5 86 115 49 68 85 85
Mitochondria 172 267 89 120 115 245 263 – 375 392 259 216 234 157 208 33 26 25 21 74 69 53 56 35
Nucleus 1 1 2 2 3 4 4 – 2 1 4 6 0 0 1 6 1 1 0 1 0 1 0 0
Nuclear Periphery 1 2 0 1 1 2 2 – 2 5 0 0 2 2 4 3 0 1 0 0 0 1 1 0
Nucleolus 1 1 0 0 1 3 11 – 9 17 8 4 4 4 8 0 2 1 0 0 1 0 0 0
Peroxisomes 8 22 24 29 25 40 29 – 21 22 8 15 32 57 74 6 7 7 41 39 71 49 70 71
SpindlePole 2 8 59 29 69 61 76 – 43 64 35 58 6 20 16 67 53 50 1 7 7 5 3 6
Vac/Vac Membrane 8 21 11 2 6 6 6 – 5 5 1 5 5 5 7 13 14 12 1 12 4 2 2 3
Unique Cell Count 206 321 219 193 256 335 382 425 452 289 266 295 288 343 208 156 166 230 369 322 258 313 313
Labelled Cell Count 263 423 306 250 328 437 500 558 581 364 371 369 365 443 270 208 206 230 369 322 258 313 313


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.0 6.1 6.0 5.5 5.9 4.7 4.9 – 4.2 4.0 3.7 4.4 5.3 5.6 5.6 6.7 7.2 6.3 5.2 5.3 5.8
Std Deviation (1e-4) 0.7 0.9 1.1 1.3 1.3 1.0 1.4 – 0.7 0.8 0.7 0.9 0.8 1.1 1.2 1.2 1.6 1.2 1.1 1.0 1.5
Intensity Change (Log2) – – – -0.12 -0.04 -0.36 -0.3 – -0.54 -0.61 -0.72 -0.45 -0.18 -0.1 -0.12 0.15 0.26 0.06 -0.23 -0.19 -0.07

WT3RAP60RAP140RAP220RAP300RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -4.2 -2.9 0 -4.6 – 0 0 0 0 -4.6 -6.1 -6.4 -1.7 -3.3 -4.3
Bud -0.5 0.5 0 -0.3 – 0 0 0 0 -0.5 -1.6 -2.6 -1.5 -2.3 -1.9
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 0.6 -1.4 0 – -3.2 -2.4 -1.3 -2.0 -1.2 -0.6 -1.4 2.8 1.2 3.7
Endoplasmic Reticulum 0 -0.6 0 0 – 0 0 0 0 0.2 0 0 1.1 0 1.6
Endosome -0.7 -0.3 0 -3.8 – 0 0 0 0 -3.3 1.7 2.5 2.3 4.7 3.7
Golgi -0.4 -2.8 0 0 – 0 0 0 0 -0.7 0.6 -1.7 1.1 1.3 -1.0
Mitochondria 4.4 0.9 0 6.8 – 0 0 0 0 9.0 3.1 4.6 -5.7 -5.0 -5.4
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 1.2 -0.4 0 -1.4 – 0 0 0 0 0 2.7 3.2 -3.3 -2.2 -2.4
SpindlePole -2.9 0 0 -2.0 – 0 0 0 0 -8.4 -6.1 -7.6 1.2 1.5 0.7
Vacuole -2.3 -1.6 -2.2 -2.5 – -3.0 -3.1 -3.4 -1.9 -2.1 -2.1 -2.0 0.6 1.5 0.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.0743 0.5272 0.8401 0.3711 0.7544 0.7919 1.1756 1.7658 1.7003 1.7919 1.5725 1.5351 0.5909 1.1357 0.837 1.5795 0.0573 0.7366
Actin 0.0753 0.0112 0.0318 0.0173 0.0243 0.0165 0.043 0.0253 0.0225 0.0337 0.0703 0.0216 0.0252 0.0237 0.0566 0.0717 0.0065 0.0222
Bud 0.0011 0.0019 0.0007 0.0004 0.0005 0.0003 0.0003 0.0008 0.0062 0.0004 0 0.0003 0.0007 0.0029 0.0006 0.0075 0.0002 0.0001
Bud Neck 0.0078 0.0008 0.0027 0.0019 0.0004 0.0015 0.0008 0.0006 0.0012 0.001 0.0002 0.0011 0.0014 0.0007 0.001 0.0025 0.0014 0.0017
Bud Periphery 0.0014 0.0014 0.0009 0.0005 0.0008 0.0003 0.0003 0.0006 0.0051 0.0005 0 0.0003 0.0012 0.003 0.0006 0.0148 0.0002 0.0002
Bud Site 0.0201 0.0133 0.0022 0.0029 0.0006 0.0007 0.0011 0.0084 0.0096 0.0009 0.0001 0.0009 0.0034 0.0048 0.0014 0.0417 0.0005 0.0004
Cell Periphery 0.0005 0.0002 0.0003 0.0002 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001 0 0.0001 0.0005 0.0002 0.0001 0.0046 0.0001 0.0001
Cytoplasm 0.0091 0.0181 0.015 0.002 0.0019 0.0021 0.0033 0.0094 0.0175 0.0019 0.0007 0.0041 0.0018 0.0161 0.0048 0.0032 0.0012 0.0016
Cytoplasmic Foci 0.1247 0.2222 0.1842 0.1397 0.1651 0.1652 0.1695 0.2076 0.2012 0.1471 0.1602 0.139 0.1971 0.2004 0.1268 0.1446 0.1429 0.1393
Eisosomes 0.0007 0.0001 0.0004 0.0004 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0 0.0001 0.0002 0.0001 0.0001 0.001 0.0001 0.0001
Endoplasmic Reticulum 0.0054 0.0009 0.0014 0.0019 0.003 0.0007 0.0013 0.0008 0.0003 0.0003 0.0003 0.0004 0.001 0.0022 0.0005 0.0022 0.0005 0.0004
Endosome 0.1968 0.2315 0.2641 0.3348 0.2194 0.1984 0.2218 0.2257 0.1778 0.1908 0.1841 0.1477 0.1954 0.2333 0.1264 0.1438 0.2237 0.1765
Golgi 0.1737 0.2269 0.2316 0.2134 0.2413 0.3341 0.2128 0.2643 0.2628 0.2481 0.2817 0.289 0.1711 0.2565 0.3016 0.2275 0.32 0.3446
Lipid Particles 0.1409 0.0783 0.0693 0.0998 0.1035 0.0497 0.0651 0.0181 0.0288 0.0208 0.111 0.0847 0.153 0.0643 0.0784 0.0762 0.1772 0.092
Mitochondria 0.0486 0.037 0.0361 0.0552 0.0927 0.0428 0.0201 0.0223 0.0361 0.0179 0.0029 0.0569 0.0188 0.0305 0.0444 0.1145 0.0222 0.0326
None 0.0051 0.0202 0.0051 0.0023 0.0012 0.0006 0.0007 0.0068 0.0007 0.0002 0.0001 0.0002 0.0004 0.013 0.0073 0.0017 0.0002 0.0002
Nuclear Periphery 0.0248 0.0006 0.0009 0.0025 0.0194 0.0038 0.0024 0.0002 0.0002 0.0002 0 0.0001 0.0004 0.0017 0.0016 0.0028 0.0002 0.0001
Nucleolus 0.0015 0.0003 0.0003 0.0006 0.0002 0.0002 0.0001 0.0001 0.0003 0.0001 0 0.0001 0.0003 0.0006 0.0002 0.0016 0.0001 0.0001
Nucleus 0.0227 0.0004 0.0003 0.0007 0.0015 0.0005 0.0003 0.0002 0.0003 0.0001 0 0.0001 0.0004 0.0006 0.0006 0.0025 0.0001 0
Peroxisomes 0.1221 0.1271 0.1466 0.1122 0.1168 0.1754 0.2514 0.205 0.2216 0.3336 0.1867 0.2499 0.2161 0.1407 0.2401 0.1137 0.0984 0.185
Punctate Nuclear 0.0092 0.0014 0.0012 0.0029 0.0015 0.0042 0.001 0.001 0.0043 0.0005 0.0002 0.0005 0.0011 0.001 0.0052 0.0016 0.0004 0.0005
Vacuole 0.0048 0.0046 0.0029 0.0045 0.0018 0.0013 0.003 0.0014 0.0022 0.0011 0.0006 0.0017 0.0085 0.0024 0.0008 0.0158 0.0022 0.0011
Vacuole Periphery 0.0037 0.0015 0.0022 0.0038 0.0038 0.0014 0.0019 0.001 0.0012 0.0008 0.0009 0.0013 0.0021 0.0014 0.0008 0.0046 0.0017 0.0014

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 13.4444 10.7308 12.7404 13.5669 6.848 9.118 13.7794 15.0853 11.544 14.0657
Translational Efficiency 0.4679 0.5026 0.4325 0.4958 0.7767 0.6458 0.5867 0.4545 0.561 0.5013

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2056 89 385 1484 1071 1933 2296 2678 3127 2022 2681 4162

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 722.65 901.49 1021.64 911.72 675.22 811.06 933.20 960.84 706.41 815.04 945.90 943.33
Standard Deviation 78.52 124.91 108.66 109.15 94.41 106.70 103.11 116.58 87.25 109.16 108.46 116.39
Intensity Change Log 2 — 0.319014 0.499518 0.335294 — 0.264451 0.466829 0.508939 — 0.292916 0.483820 0.421782

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.002760 0.015757 0.033913 0.034148 0.001906 0.002689 0.010578 0.012637 0.002468 0.003264 0.013929 0.020307
Bud Neck 0.002397 0.000727 0.003526 0.004477 0.002033 0.000625 0.001983 0.003612 0.002272 0.000630 0.002205 0.003920
Bud Site 0.002904 0.013187 0.022115 0.037860 0.003379 0.002010 0.009715 0.022732 0.003066 0.002502 0.011496 0.028126
Cell Periphery 0.000076 0.000137 0.000115 0.000077 0.000125 0.000053 0.000038 0.000047 0.000093 0.000057 0.000049 0.000058
Cytoplasm 0.004848 0.003122 0.006451 0.031618 0.005013 0.002634 0.008703 0.025633 0.004904 0.002655 0.008379 0.027767
Cytoplasmic Foci 0.201798 0.280224 0.310951 0.325777 0.195490 0.201859 0.360262 0.297539 0.199637 0.205308 0.353180 0.307608
Eisosomes 0.000173 0.000103 0.000099 0.000102 0.000143 0.000087 0.000062 0.000058 0.000163 0.000088 0.000067 0.000074
Endoplasmic Reticulum 0.000162 0.000279 0.003650 0.000804 0.000183 0.000132 0.000667 0.000286 0.000169 0.000138 0.001095 0.000471
Endosome 0.118865 0.171930 0.142270 0.147901 0.151817 0.183067 0.197943 0.172846 0.130151 0.182577 0.189948 0.163952
Golgi 0.489914 0.374939 0.097932 0.130087 0.450442 0.497778 0.175299 0.177196 0.476395 0.492371 0.164189 0.160399
Lipid Particles 0.022597 0.007509 0.026414 0.006226 0.032914 0.013292 0.012044 0.003523 0.026130 0.013037 0.014107 0.004487
Mitochondria 0.078826 0.030446 0.003881 0.006838 0.085265 0.051453 0.014785 0.027698 0.081032 0.050528 0.013219 0.020260
Mitotic Spindle 0.004592 0.021852 0.217125 0.079018 0.006275 0.005205 0.112305 0.131566 0.005168 0.005938 0.127357 0.112830
None 0.000121 0.000019 0.000052 0.000043 0.000232 0.000067 0.000066 0.000079 0.000159 0.000065 0.000064 0.000066
Nuclear Periphery 0.000027 0.000019 0.000348 0.000227 0.000053 0.000054 0.000185 0.000184 0.000036 0.000053 0.000208 0.000199
Nuclear Periphery Foci 0.000144 0.000115 0.005898 0.000935 0.000221 0.000195 0.001295 0.000394 0.000171 0.000191 0.001956 0.000587
Nucleolus 0.000192 0.000046 0.000238 0.000132 0.000463 0.000071 0.000385 0.000194 0.000285 0.000070 0.000364 0.000172
Nucleus 0.000120 0.000064 0.002639 0.001484 0.000610 0.000148 0.000640 0.001139 0.000288 0.000145 0.000927 0.001262
Peroxisomes 0.065493 0.073280 0.095014 0.145291 0.058503 0.032352 0.068330 0.077735 0.063099 0.034153 0.072162 0.101823
Vacuole 0.002104 0.003204 0.025969 0.044939 0.002043 0.003474 0.022689 0.040859 0.002083 0.003462 0.023160 0.042314
Vacuole Periphery 0.001888 0.003044 0.001401 0.002016 0.002893 0.002754 0.002027 0.004042 0.002232 0.002767 0.001937 0.003320

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.29 -6.30 -10.94 -1.61 0.10 -1.42 -7.82 -9.10 -8.22 -1.17 -1.18 -9.56 -13.79 -12.13 -3.50
Bud Neck 4.14 -2.39 -5.38 -10.20 -1.37 3.92 -0.49 -5.60 -11.38 -6.44 5.80 -0.74 -7.18 -15.09 -7.50
Bud Site -1.38 -5.87 -14.84 -3.44 -4.01 1.43 -5.96 -13.06 -16.21 -9.34 0.90 -10.06 -20.63 -20.81 -12.21
Cell Periphery -1.05 -3.75 -0.48 0.98 4.00 4.95 6.40 5.70 0.92 -3.75 3.84 5.48 4.34 -0.45 -2.81
Cytoplasm 1.35 -1.43 -12.70 -12.50 -9.46 2.68 -4.69 -15.07 -17.45 -11.67 3.71 -5.63 -20.10 -21.79 -15.02
Cytoplasmic Foci -4.85 -8.50 -18.63 -1.95 -0.99 -1.14 -26.96 -16.06 -17.83 12.63 -1.40 -31.89 -24.68 -21.56 10.58
Eisosomes 2.32 3.27 3.44 -0.01 0.24 4.84 7.77 8.22 4.97 1.21 5.15 6.91 6.50 2.43 -1.68
Endoplasmic Reticulum -1.04 -5.29 -5.04 -4.02 4.12 1.88 -5.12 -4.87 -6.46 3.27 0.74 -7.12 -6.03 -7.12 3.98
Endosome -3.74 -2.59 -4.03 2.23 -0.17 -4.97 -7.03 -2.14 3.72 6.32 -11.20 -13.25 -6.90 5.91 7.51
Golgi 4.60 47.83 52.80 10.43 -3.44 -5.05 32.45 33.06 51.17 1.15 -2.34 56.10 60.78 57.52 2.62
Lipid Particles 4.33 -1.64 8.44 0.15 7.70 6.15 6.79 10.04 6.64 9.01 6.49 6.57 13.68 5.90 10.58
Mitochondria 4.67 20.56 20.14 2.44 -2.17 5.78 13.53 11.04 7.63 -6.15 7.59 22.18 20.04 10.47 -4.36
Mitotic Spindle -2.27 -14.30 -16.34 -6.85 8.62 0.71 -22.56 -27.87 -28.99 -3.80 -0.77 -27.17 -32.86 -32.31 1.81
None 5.49 2.23 3.53 -4.41 0.75 2.45 2.13 1.88 -1.79 -0.78 3.29 2.34 2.60 -1.32 -0.32
Nuclear Periphery 0.77 -5.98 -2.71 -2.81 1.20 -0.04 -6.41 -6.22 -4.94 -1.19 -0.54 -9.84 -6.05 -4.54 -0.47
Nuclear Periphery Foci 0.65 -4.92 -4.26 -4.36 4.15 0.47 -4.37 -3.44 -3.32 3.42 -0.34 -6.54 -5.62 -4.99 4.71
Nucleolus 1.44 -1.26 0.09 -3.86 1.65 3.23 -0.19 1.32 -6.11 1.35 2.76 -1.35 0.35 -6.84 1.78
Nucleus 1.37 -3.26 -5.11 -5.22 1.28 2.43 -0.90 -4.12 -5.38 -3.57 1.41 -4.13 -6.77 -7.10 -2.94
Peroxisomes -0.52 -3.02 -12.11 -4.30 -4.48 6.53 -2.06 -3.79 -12.22 -1.80 9.48 -2.31 -9.95 -18.92 -6.69
Vacuole -1.21 -6.91 -16.88 -16.20 -5.46 -3.64 -14.46 -22.28 -21.52 -8.87 -3.74 -15.98 -27.86 -26.90 -11.17
Vacuole Periphery -1.03 1.91 -0.05 0.97 -1.20 0.34 2.30 -2.06 -2.99 -5.28 -2.18 1.49 -3.23 -1.28 -4.46
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Member of the ChAPs (Chs5p-Arf1p-binding proteins) family; part of the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BCH2 has a paralog, CHS6, that arose from the whole genome duplication
Localization
Cell Percentages —
Cell Cycle Regulation No
Subcompartmental Group N/A

Bch2

Bch2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bch2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available