Standard name
Human Ortholog
Description Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic homodimeric protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.06 0.21 0.2 0.16 0.17 0.12 0.06 0.1 0.07 0.1 0.08 0.11 0.17 0.1 0 0.11 0.07 0.13 0.05 0.08 0 0.06 0.08 0.09
Bud 0 0 0.05 0 0 0.06 0.05 0.06 0 0.05 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.09 0 0.09 0.05 0.08 0.05 0.1 0 0.06 0.06 0 0 0 0.06 0.09 0.05 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.06 0.07 0 0 0 0 0 0 0 0 0 0.07 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.41 0.18 0.39 0.4 0.34 0.25 0.39 0.31 0.29 0.31 0.25 0.26 0.38 0.42 0.41 0.45 0.35 0.36 0.3 0.32 0.31 0.33 0.25 0.24
Golgi 0.36 0.52 0.29 0.34 0.43 0.07 0.24 0.21 0.18 0.12 0.13 0.11 0.38 0.4 0.41 0.26 0.38 0.39 0.39 0.42 0.45 0.43 0.47 0.52
Mitochondria 0.29 0.26 0.12 0.12 0.07 0.62 0.17 0.22 0.45 0.37 0.53 0.5 0.25 0.2 0.16 0.1 0.17 0.12 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0.07 0 0 0 0.06 0.05 0.05 0.05 0.09 0.05 0 0 0 0.05 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.07 0 0 0 0 0.17 0.07 0.11 0.13 0.13 0.1
SpindlePole 0.07 0 0.07 0.11 0.13 0.05 0.13 0.12 0.08 0.16 0.07 0.12 0 0.06 0.05 0.2 0.25 0.13 0 0 0.05 0 0 0
Vac/Vac Membrane 0.09 0.07 0.12 0 0 0.05 0.1 0.09 0.05 0.06 0 0.06 0 0 0 0 0.06 0.07 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 32 8 32 50 28 19 28 19 26 27 41 48 43 17 26 16 29 5 15 2 16 33 31
Bud 2 4 2 7 9 13 14 16 9 13 22 25 9 6 6 8 2 4 0 2 0 0 1 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 1 0 0 0 0 2 1 0 0 1 4 3 0 0 0 1 0 0 – – – – – –
Cell Periphery 0 4 0 1 1 2 1 2 4 1 2 1 1 1 0 1 1 1 0 0 0 0 0 0
Cytoplasm 4 13 0 18 14 18 14 27 11 17 20 16 9 10 25 21 12 19 0 2 0 0 3 5
Endoplasmic Reticulum 4 9 3 3 3 7 11 6 4 5 3 6 18 14 5 5 9 5 0 1 0 0 1 0
Endosome 42 27 16 80 98 57 119 87 81 83 82 95 105 182 172 104 83 80 34 66 23 84 106 86
Golgi 37 77 12 68 124 16 73 58 51 32 44 41 104 173 174 60 88 87 44 86 33 110 201 192
Mitochondria 30 39 5 24 19 140 52 62 124 100 176 179 68 86 66 22 39 27 2 4 1 3 6 6
Nucleus 0 0 0 0 0 3 0 1 1 1 1 5 0 0 0 1 1 2 0 0 0 0 0 0
Nuclear Periphery 0 1 0 0 0 2 1 3 2 0 2 2 2 1 3 3 2 0 0 0 0 0 0 1
Nucleolus 2 2 3 2 2 6 19 14 14 13 30 19 4 5 11 11 9 8 0 0 0 0 0 0
Peroxisomes 2 3 0 6 2 3 7 8 4 11 15 9 14 30 13 3 4 0 19 13 8 33 55 37
SpindlePole 7 3 3 22 37 12 39 33 21 44 24 43 12 28 20 46 59 28 3 4 3 4 8 3
Vac/Vac Membrane 9 10 5 4 11 11 30 24 15 17 14 23 9 13 14 10 15 15 0 4 0 1 2 1
Unique Cell Count 102 149 41 198 289 227 302 278 278 271 334 361 276 436 421 229 234 222 114 205 75 258 425 368
Labelled Cell Count 146 224 57 267 370 320 400 369 360 364 466 508 403 592 526 322 340 305 114 205 75 258 425 368


Late Golgi

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.2 9.8 8.7 9.2 10.3 6.8 9.0 8.6 8.5 8.5 8.1 8.2 9.4 9.7 9.9 9.4 10.1 10.5 8.5 8.7 8.8
Std Deviation (1e-4) 1.3 1.2 1.1 1.6 1.5 1.6 1.4 1.5 1.4 1.4 1.5 1.5 1.4 1.7 1.5 1.9 1.8 1.9 1.3 1.5 1.6
Intensity Change (Log2) – – – 0.08 0.25 -0.35 0.04 -0.01 -0.04 -0.03 -0.11 -0.09 0.11 0.15 0.18 0.11 0.21 0.26 -0.04 0.0 0.01

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -0.5 -0.3 -1.2 0 0 0 0 0 0 -0.3 0 0 -1.5 0 -1.1
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0.2 -0.6 -1.8 0 -1.0 -1.3 -1.1 -2.0 -1.7 -0.1 0.3 0.2 0.8 -0.4 -0.4
Golgi 0.6 1.7 0 -0.7 -1.2 -1.6 -3.0 -2.7 -3.2 1.0 1.3 1.5 -0.4 1.0 1.2
Mitochondria 0 0 5.9 0.8 1.5 3.9 3.1 4.9 4.6 1.8 1.2 0.6 0 0.7 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1.0 0 0 1.5 0 0 0 0 0 2.0 2.5 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.5841 4.3468 4.0773 3.9603 2.8757 4.253 4.8283 6.3106 5.9713 5.1459 5.0164 5.8103 6.8514 8.1972 7.1917 7.7715 6.9614 7.7931
Actin 0.0739 0.0205 0.02 0.0255 0.0196 0.037 0.0504 0.0131 0.0084 0.0306 0.0019 0.046 0.0635 0.0473 0.0257 0.0227 0.0111 0.0532
Bud 0.0006 0.0002 0.0003 0.0014 0.0001 0.0002 0.0004 0.0002 0.0002 0.0015 0.0002 0.0004 0.0004 0.0005 0.0002 0.0001 0.0007 0.0003
Bud Neck 0.0047 0.0004 0.0007 0.0013 0.0003 0.001 0.0022 0.0004 0.0005 0.0034 0.0006 0.0011 0.0006 0.0011 0.0013 0.0004 0.0009 0.0017
Bud Periphery 0.0008 0.0001 0.0002 0.0019 0.0001 0.0001 0.0004 0.0001 0.0002 0.0019 0.0001 0.001 0.0004 0.0005 0.0002 0.0001 0.001 0.0003
Bud Site 0.0086 0.001 0.0126 0.0071 0.0001 0.0003 0.0015 0.0012 0.0004 0.0049 0.0005 0.0006 0.002 0.0103 0.0015 0.0004 0.0035 0.0008
Cell Periphery 0.0002 0 0.0001 0.0003 0 0.0001 0.0002 0 0.0001 0.0003 0 0.0001 0.0001 0.0005 0.0001 0 0.0002 0.0001
Cytoplasm 0.0081 0.0097 0.0013 0.0024 0.0009 0.0017 0.007 0.0021 0.0016 0.0094 0.0024 0.0019 0.0031 0.0023 0.0145 0.0025 0.0059 0.0032
Cytoplasmic Foci 0.2069 0.236 0.2192 0.223 0.2017 0.1553 0.1899 0.2403 0.1658 0.2149 0.2305 0.1634 0.1763 0.224 0.1948 0.1886 0.1767 0.1474
Eisosomes 0.0006 0 0 0.0002 0 0 0.0003 0 0.0001 0.0002 0 0.0001 0.0002 0.0002 0.0003 0.0003 0.0001 0.0001
Endoplasmic Reticulum 0.0043 0.0006 0.0002 0.0029 0.0003 0.0005 0.0036 0.0002 0.0005 0.0029 0.0003 0.0011 0.0025 0.0004 0.0016 0.0003 0.0082 0.0013
Endosome 0.2007 0.1764 0.1541 0.1635 0.1936 0.122 0.2158 0.2365 0.21 0.3414 0.206 0.1726 0.1653 0.1961 0.1717 0.1897 0.2374 0.1629
Golgi 0.3077 0.377 0.4299 0.3683 0.4472 0.5044 0.2949 0.3956 0.4938 0.269 0.3934 0.4559 0.2909 0.36 0.3743 0.4044 0.3571 0.4136
Lipid Particles 0.054 0.0248 0.0164 0.0151 0.0312 0.0431 0.0478 0.0449 0.0231 0.0189 0.0077 0.0339 0.0545 0.0251 0.0262 0.0184 0.0939 0.046
Mitochondria 0.011 0.0072 0.0077 0.0176 0.0012 0.014 0.0134 0.0037 0.0287 0.0045 0.0035 0.0124 0.017 0.0112 0.0138 0.0072 0.0172 0.0112
None 0.0013 0.0002 0.0001 0.0005 0.0001 0.0001 0.0028 0.0001 0.0129 0.0559 0.0001 0.0003 0.0031 0.0003 0.0065 0.023 0.0034 0.0001
Nuclear Periphery 0.0065 0.0004 0 0.002 0.0001 0.0009 0.0185 0.0001 0.0011 0.0028 0.0001 0.0153 0.0071 0.0002 0.0011 0.0001 0.0269 0.0004
Nucleolus 0.0008 0.0001 0 0.0003 0 0.0001 0.0013 0.0001 0.0003 0.0005 0.0001 0.0006 0.0003 0.0002 0.0001 0 0.0013 0.0004
Nucleus 0.003 0.0002 0 0.001 0 0.0003 0.0114 0.0001 0.0002 0.0012 0.0001 0.0071 0.0009 0.0002 0.0007 0 0.0098 0.0002
Peroxisomes 0.0999 0.1418 0.136 0.1604 0.1006 0.1115 0.1226 0.0573 0.0483 0.0244 0.1488 0.0788 0.2056 0.1053 0.1623 0.1394 0.0283 0.1514
Punctate Nuclear 0.0029 0.001 0.0003 0.0008 0.0021 0.0059 0.0109 0.0012 0.0008 0.0048 0.0003 0.0027 0.004 0.0121 0.0016 0.0007 0.007 0.0008
Vacuole 0.0017 0.0016 0.0004 0.0028 0.0003 0.0006 0.0027 0.0013 0.0016 0.0045 0.0023 0.0021 0.0011 0.0014 0.0007 0.0007 0.0055 0.003
Vacuole Periphery 0.0018 0.0007 0.0005 0.0018 0.0006 0.0008 0.0022 0.0015 0.0013 0.0023 0.001 0.0025 0.0012 0.0009 0.0008 0.0008 0.0038 0.0016

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 35.0739 32.2013 40.2438 35.769 39.3295 43.5812 40.6984 47.4196 53.7313 41.1242
Translational Efficiency 1.7698 2.1904 1.3397 1.5131 1.5541 1.3958 1.5319 1.3456 1.0132 1.6929

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1466 171 635 1546 2187 1853 1249 984 3653 2024 1884 2530

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 911.19 989.28 1215.41 1140.53 877.40 1028.57 1104.34 1196.66 890.96 1025.25 1141.78 1162.36
Standard Deviation 130.54 162.83 146.52 152.99 110.61 141.53 140.49 173.36 120.16 143.86 151.92 163.53
Intensity Change Log 2 — 0.118627 0.415619 0.323881 — 0.229333 0.331878 0.447707 — 0.173996 0.375147 0.385952

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.008710 0.021163 0.025853 0.062481 0.003541 0.006230 0.038451 0.041338 0.005616 0.007491 0.034205 0.054258
Bud Neck 0.000404 0.000739 0.001316 0.000717 0.000156 0.000440 0.000650 0.001955 0.000255 0.000465 0.000875 0.001198
Bud Site 0.002734 0.003657 0.010879 0.011908 0.000824 0.001301 0.009540 0.027065 0.001591 0.001500 0.009992 0.017803
Cell Periphery 0.000060 0.000060 0.000065 0.000076 0.000023 0.000043 0.000067 0.000080 0.000038 0.000045 0.000067 0.000078
Cytoplasm 0.001875 0.001532 0.002382 0.005634 0.001238 0.001009 0.002695 0.012362 0.001494 0.001053 0.002590 0.008251
Cytoplasmic Foci 0.353594 0.381597 0.418881 0.341461 0.351561 0.408227 0.415984 0.338343 0.352377 0.405977 0.416961 0.340248
Eisosomes 0.000063 0.000061 0.000056 0.000095 0.000041 0.000038 0.000083 0.000061 0.000050 0.000040 0.000074 0.000082
Endoplasmic Reticulum 0.000398 0.000358 0.001499 0.000684 0.000090 0.000162 0.000836 0.000601 0.000213 0.000178 0.001060 0.000652
Endosome 0.191107 0.216812 0.169451 0.212744 0.156970 0.215199 0.201921 0.191531 0.170670 0.215335 0.190977 0.204494
Golgi 0.338774 0.245320 0.202425 0.259351 0.421473 0.269443 0.229852 0.140648 0.388285 0.267405 0.220608 0.213184
Lipid Particles 0.023408 0.035195 0.015929 0.009719 0.014152 0.023528 0.016949 0.010154 0.017866 0.024514 0.016605 0.009888
Mitochondria 0.009280 0.002007 0.000873 0.001779 0.009138 0.004265 0.000840 0.002344 0.009195 0.004074 0.000851 0.001999
Mitotic Spindle 0.006641 0.013523 0.111098 0.023575 0.006554 0.011498 0.028093 0.110289 0.006589 0.011669 0.056070 0.057301
None 0.000023 0.000017 0.000013 0.000010 0.000018 0.000011 0.000011 0.000016 0.000020 0.000011 0.000012 0.000013
Nuclear Periphery 0.000038 0.000034 0.000242 0.000051 0.000011 0.000024 0.000060 0.000104 0.000022 0.000025 0.000121 0.000071
Nuclear Periphery Foci 0.000311 0.000489 0.003559 0.000648 0.000127 0.000333 0.001486 0.001043 0.000201 0.000346 0.002185 0.000802
Nucleolus 0.000102 0.000069 0.000014 0.000006 0.000054 0.000012 0.000006 0.000027 0.000073 0.000017 0.000009 0.000014
Nucleus 0.000093 0.000128 0.000063 0.000029 0.000055 0.000027 0.000020 0.000231 0.000070 0.000036 0.000035 0.000108
Peroxisomes 0.058421 0.068093 0.017349 0.057421 0.032191 0.055969 0.043854 0.099960 0.042717 0.056993 0.034921 0.073966
Vacuole 0.002638 0.004136 0.016500 0.009771 0.001130 0.001514 0.007601 0.020092 0.001736 0.001735 0.010601 0.013785
Vacuole Periphery 0.001325 0.005009 0.001552 0.001839 0.000653 0.000729 0.000999 0.001756 0.000923 0.001090 0.001186 0.001807

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.33 -4.45 -12.77 -6.25 -6.46 -2.94 -11.29 -9.60 -8.77 -0.24 -1.86 -11.68 -16.40 -15.39 -5.09
Bud Neck -1.19 -6.21 -4.24 -0.05 3.87 -1.51 -8.01 -11.59 -7.61 -8.73 -1.21 -9.46 -12.61 -5.08 -4.50
Bud Site -0.91 -5.85 -8.96 -6.28 -0.22 -2.20 -8.11 -13.79 -13.56 -8.59 0.32 -9.82 -16.76 -16.90 -6.47
Cell Periphery 0.07 -1.08 -2.76 -1.77 -1.67 -1.17 -7.99 -10.89 -2.36 -2.10 -0.43 -6.73 -11.26 -2.22 -2.33
Cytoplasm 0.55 -1.51 -5.23 -6.10 -4.10 0.55 -3.69 -8.76 -8.99 -8.03 1.28 -3.71 -10.40 -11.27 -9.14
Cytoplasmic Foci -1.79 -6.09 1.92 2.65 7.39 -9.23 -9.13 3.43 10.33 10.36 -9.92 -10.98 3.57 12.06 12.97
Eisosomes 0.24 1.39 -6.65 -4.17 -7.39 1.37 -8.86 -4.47 -5.59 4.17 4.27 -6.83 -9.78 -13.18 -1.65
Endoplasmic Reticulum 0.30 -3.33 -2.25 -2.41 2.47 -1.54 -3.92 -3.17 -2.65 0.84 0.63 -4.99 -4.69 -4.90 2.18
Endosome -1.84 3.32 -3.55 0.36 -6.50 -11.19 -8.54 -4.24 4.60 2.63 -9.45 -4.72 -7.32 2.82 -2.22
Golgi 6.07 15.31 10.83 -0.78 -6.37 24.09 28.07 40.89 20.12 13.24 22.20 30.78 33.41 10.28 1.88
Lipid Particles -1.35 2.68 5.59 2.96 3.91 -3.82 -1.44 1.88 5.59 3.46 -2.84 0.67 5.48 6.75 5.15
Mitochondria 4.55 7.07 6.12 0.20 -2.05 4.55 8.73 6.19 2.61 -2.24 5.86 11.25 9.02 3.70 -3.17
Mitotic Spindle -1.32 -11.86 -6.79 -1.99 9.47 -2.98 -7.33 -15.08 -14.25 -11.45 -3.32 -13.51 -15.94 -13.63 -1.10
None 0.80 2.26 3.64 0.99 2.03 1.79 1.69 -0.75 -3.50 -3.38 2.85 2.67 1.75 -1.93 -1.64
Nuclear Periphery 0.17 -6.25 -0.86 -1.33 6.52 -1.69 -7.03 -10.33 -8.03 -5.30 -0.29 -7.91 -7.18 -6.84 3.25
Nuclear Periphery Foci -1.08 -4.84 -2.63 -1.06 4.21 -2.06 -2.35 -6.65 -5.01 0.63 -1.56 -4.13 -6.74 -4.37 2.68
Nucleolus 0.39 1.53 1.72 1.08 2.19 1.01 1.15 0.27 -5.30 -7.24 1.67 1.90 1.59 -0.57 -3.79
Nucleus -0.39 -0.61 1.39 1.10 1.37 0.74 0.91 -1.83 -1.88 -1.89 1.12 0.09 -1.68 -1.85 -1.70
Peroxisomes -0.80 10.49 0.21 0.88 -10.31 -6.54 -3.10 -11.16 -6.45 -8.31 -4.09 2.70 -8.51 -3.65 -10.07
Vacuole -1.01 -8.22 -8.07 -3.73 3.41 -1.85 -9.21 -10.56 -10.43 -8.06 -0.03 -11.86 -13.30 -13.29 -5.30
Vacuole Periphery -0.96 -0.72 -0.99 0.82 -0.52 -0.67 -2.09 -1.83 -1.68 -1.17 -0.48 -1.66 -2.28 -1.39 -1.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Core component of transport protein particle (TRAPP) complexes I-III; TRAPP complexes are related multimeric guanine nucleotide-exchange factors for the GTPase Ypt1, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII); hydrophilic homodimeric protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles
Localization
Cell Percentages Golgi (17%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Bet3

Bet3


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Bet3-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available