Standard name
Human Ortholog
Description S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR); glutathione transferase involved in cell-surface biosynthesis and architecture; catalyzes glutathione (GSH)-dependent reduction of GS-trichloro-p-hydroquinone to trichloro-p-hydroquinone; expression upregulated upon exposure to genotoxic agents, such as methyl methanesulfonate, cisplatin and bleomycin; not an essential gene; similar to YGR154C; green fluorescent protein (GFP)-fusion protein localizes to cytoplasm
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0.07 0 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.11 0.05 0 0 0 0 0 0 0
Cytoplasm 0.92 0.97 0.95 0.98 0.97 0.88 0.74 0.77 0.59 0.62 0.56 0.54 0.96 0.98 0.99 0.98 0.92 0.96 0.78 0.85 0.7 0.9 0.85 0.86
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.09 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.16 0 0.05 0.05 0.05 0.2 0.39 0.27 0.55 0.47 0.55 0.53 0 0 0 0 0 0 0.09 0.06 0.14 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0.08 0.06 0.09 0 0.05 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 1 0 2 1
Bud 1 0 4 0 1 0 6 4 6 6 9 6 0 0 0 0 0 0 2 0 0 0 1 3
Bud Neck 0 0 1 5 3 0 1 1 0 0 0 2 1 0 0 0 0 0 0 0 0 0 1 0
Bud Site 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 4 1 2 0 0 0 1 2 1 0 0 1 15 7 4 1 0 1 0 0 0
Cytoplasm 220 142 56 165 226 185 197 165 110 149 92 116 92 147 161 133 135 141 196 125 66 101 150 139
Endoplasmic Reticulum 2 2 0 0 0 0 0 0 4 0 0 0 1 0 0 4 10 13 1 0 1 1 2 0
Endosome 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 2 0 7 2 0 0 3 2
Golgi 1 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0
Mitochondria 39 3 3 8 11 43 103 58 101 112 89 114 1 1 0 1 4 6 22 8 13 3 6 6
Nucleus 0 0 2 1 1 0 3 4 2 2 4 7 1 0 0 0 1 1 0 0 0 0 0 0
Nuclear Periphery 2 1 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 1 0 1 2 2 0 2 0 2 0 0 0 0 0 0 3 1 1 2 1 1
Vac/Vac Membrane 1 1 0 0 0 7 12 5 7 18 9 20 0 7 5 3 4 3 4 2 1 0 1 1
Unique Cell Count 238 147 59 168 232 211 267 215 185 239 163 214 96 150 163 136 146 147 251 147 94 112 176 163
Labelled Cell Count 266 150 67 184 245 241 325 241 231 292 205 268 96 155 167 156 164 170 251 147 94 112 176 163


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 5.0 4.3 4.7 5.2 4.3 4.1 4.6 4.0 4.5 4.2 4.6 5.2 6.6 6.9 6.7 6.4 6.4 4.5 5.7 5.9
Std Deviation (1e-4) 0.7 1.4 1.2 2.1 1.9 1.6 1.6 1.8 1.4 1.5 1.5 1.5 1.5 2.6 2.4 1.4 1.7 1.9 1.7 2.9 2.4
Intensity Change (Log2) – – – 0.11 0.28 0.01 -0.06 0.11 -0.1 0.05 -0.04 0.08 0.28 0.61 0.69 0.63 0.56 0.56 0.06 0.4 0.46

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 1.0 -1.6 -3.5 -3.1 -5.1 -4.8 -5.4 -5.7 0.3 1.2 1.7 1.1 -0.6 0.3
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.621 1.3513 0.9728 0.982 0.5652 0.9184 0.2285 0.4991 0.4056 0.0035 0.9661 0.4847 0.5492 -0.2208 -0.4407 -0.5022 -0.3178 -0.6832
Actin 0.0292 0.0004 0.0033 0.0026 0.0074 0.0088 0.0252 0.0054 0.0112 0.0025 0.0493 0.012 0.0698 0.0021 0.0215 0.0229 0.0059 0.0184
Bud 0.0042 0.0015 0.0064 0.0147 0.0011 0.001 0.0008 0.0088 0.0006 0.0135 0.0004 0.0003 0.0045 0.006 0.0045 0.0005 0.0004 0.0023
Bud Neck 0.0013 0.0003 0.0009 0.0006 0.0003 0.0035 0.0044 0.0011 0.0005 0.0005 0.0004 0.0021 0.011 0.0005 0.003 0.0011 0.0009 0.003
Bud Periphery 0.003 0.0004 0.0043 0.0037 0.0017 0.0021 0.0012 0.0046 0.0011 0.0119 0.0006 0.0006 0.006 0.0037 0.0068 0.0012 0.0009 0.0052
Bud Site 0.0045 0.0057 0.0046 0.0022 0.0014 0.001 0.0033 0.0103 0.0017 0.0032 0.0008 0.0004 0.021 0.0291 0.0099 0.0035 0.0019 0.003
Cell Periphery 0.0004 0.0002 0.0002 0.0004 0 0.0001 0.0005 0.0004 0.0002 0.0003 0.0001 0.0001 0.0008 0.0007 0.0005 0.0008 0.0002 0.0003
Cytoplasm 0.2741 0.4117 0.3266 0.3982 0.3547 0.395 0.2092 0.2996 0.2261 0.2421 0.1803 0.2766 0.1632 0.2696 0.2334 0.308 0.3506 0.3467
Cytoplasmic Foci 0.0295 0.0354 0.022 0.0365 0.0381 0.0345 0.0296 0.0126 0.0213 0.0353 0.0389 0.0259 0.0589 0.0125 0.0244 0.0215 0.0258 0.0192
Eisosomes 0.0004 0.0001 0.0001 0.0003 0.0001 0.0001 0.0006 0.0001 0.0002 0.0001 0.0002 0.0003 0.0014 0.0002 0.0004 0.0018 0.0002 0.0002
Endoplasmic Reticulum 0.0037 0.0044 0.002 0.0017 0.0008 0.0017 0.0016 0.0012 0.0015 0.0022 0.0012 0.0011 0.0092 0.0013 0.0034 0.0024 0.0022 0.0023
Endosome 0.0184 0.0062 0.0178 0.0104 0.0056 0.0087 0.0094 0.0036 0.0054 0.0088 0.0122 0.0057 0.04 0.002 0.018 0.0076 0.017 0.0077
Golgi 0.0056 0.0005 0.0016 0.0026 0.0041 0.0016 0.0046 0.0006 0.0019 0.006 0.0089 0.0024 0.0117 0.0007 0.0098 0.0064 0.0019 0.0037
Lipid Particles 0.0097 0.0008 0.0014 0.0167 0.0015 0.003 0.0166 0.0011 0.0031 0.0181 0.0297 0.0039 0.0306 0.0003 0.0088 0.013 0.0077 0.0028
Mitochondria 0.0104 0.001 0.003 0.0051 0.008 0.0062 0.0184 0.0015 0.0195 0.0034 0.0031 0.0052 0.0076 0.001 0.013 0.02 0.0077 0.0026
None 0.5746 0.5184 0.5923 0.4867 0.5617 0.516 0.6272 0.6391 0.6772 0.6182 0.539 0.6392 0.4626 0.664 0.6168 0.5685 0.5028 0.5711
Nuclear Periphery 0.0035 0.002 0.0017 0.0011 0.0005 0.0012 0.0013 0.0005 0.0017 0.0022 0.0046 0.0019 0.0273 0.0004 0.0044 0.0009 0.0096 0.0015
Nucleolus 0.0018 0.0003 0.0005 0.0005 0.0002 0.0003 0.0019 0.0005 0.0006 0.001 0.0007 0.0011 0.0022 0.0004 0.0007 0.0002 0.0073 0.0003
Nucleus 0.0084 0.0042 0.0031 0.0039 0.0017 0.0016 0.0057 0.0023 0.004 0.0074 0.0013 0.0022 0.0093 0.0021 0.0033 0.0015 0.0088 0.0023
Peroxisomes 0.008 0.0018 0.0017 0.0072 0.0078 0.0077 0.0267 0.0012 0.0125 0.0056 0.0866 0.0112 0.0388 0.0006 0.0059 0.0145 0.0047 0.0025
Punctate Nuclear 0.0065 0.0026 0.0042 0.0026 0.0026 0.0043 0.0087 0.0042 0.006 0.0141 0.0409 0.0066 0.0111 0.0014 0.0074 0.0015 0.0382 0.0031
Vacuole 0.0023 0.0018 0.0021 0.0019 0.0006 0.0012 0.0024 0.0011 0.0028 0.0029 0.0006 0.0008 0.0089 0.0016 0.0029 0.0015 0.0026 0.0014
Vacuole Periphery 0.0006 0.0003 0.0005 0.0005 0.0002 0.0003 0.0008 0.0002 0.0011 0.0007 0.0004 0.0003 0.0041 0.0001 0.0013 0.0005 0.0026 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 12.3922 5.3174 4.6034 10.1091 8.9976 27.7432 14.1131 16.0268 18.1524 14.7052
Translational Efficiency 1.4314 1.3761 1.1446 0.7026 0.7226 0.9454 1.0324 0.85 0.8873 0.7947

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
36 378 2458 664 1338 2419 121 1387 1374 2797 2579 2051

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1040.48 699.47 868.63 870.60 671.99 728.03 951.97 900.23 681.64 724.17 872.54 890.64
Standard Deviation 259.26 118.94 114.95 123.85 84.60 94.57 117.29 145.39 110.43 98.70 116.41 139.48
Intensity Change Log 2 — -0.572915 -0.260436 -0.257167 — 0.115558 0.502476 0.421854 — -0.262588 0.088335 0.048347

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003662 0.000966 0.000119 0.008494 0.000350 0.000469 0.000299 0.002910 0.000437 0.000537 0.000128 0.004717
Bud Neck 0.009970 0.056054 0.003866 0.008985 0.016759 0.042744 0.001663 0.013081 0.016581 0.044543 0.003762 0.011755
Bud Site 0.132403 0.042429 0.007254 0.057926 0.005158 0.019031 0.004550 0.061549 0.008492 0.022193 0.007127 0.060376
Cell Periphery 0.000599 0.000321 0.000083 0.000191 0.000129 0.000150 0.000238 0.000478 0.000141 0.000173 0.000090 0.000385
Cytoplasm 0.291029 0.277771 0.466342 0.437672 0.482124 0.419785 0.335976 0.408386 0.477117 0.400593 0.460226 0.417867
Cytoplasmic Foci 0.189387 0.302323 0.005406 0.057430 0.245891 0.255161 0.050248 0.085062 0.244411 0.261534 0.007510 0.076116
Eisosomes 0.000092 0.000205 0.000016 0.000082 0.000161 0.000153 0.000136 0.000058 0.000159 0.000160 0.000022 0.000066
Endoplasmic Reticulum 0.015813 0.001230 0.001562 0.004090 0.001096 0.000522 0.003321 0.001586 0.001482 0.000617 0.001645 0.002397
Endosome 0.045672 0.058753 0.000908 0.009926 0.012530 0.022863 0.006672 0.026107 0.013398 0.027713 0.001179 0.020869
Golgi 0.025247 0.012489 0.000042 0.001627 0.003201 0.008011 0.000100 0.010996 0.003779 0.008616 0.000045 0.007963
Lipid Particles 0.006974 0.013942 0.000513 0.003232 0.009069 0.006613 0.004423 0.002391 0.009014 0.007604 0.000696 0.002663
Mitochondria 0.011213 0.020817 0.000813 0.002683 0.007431 0.013724 0.000356 0.005584 0.007530 0.014682 0.000791 0.004645
Mitotic Spindle 0.040610 0.005936 0.003042 0.027800 0.001823 0.010373 0.000371 0.081764 0.002839 0.009774 0.002916 0.064294
None 0.002704 0.006406 0.004765 0.004210 0.002597 0.002710 0.002445 0.002513 0.002599 0.003210 0.004657 0.003062
Nuclear Periphery 0.001773 0.000780 0.001755 0.001231 0.000387 0.000305 0.001608 0.001173 0.000424 0.000369 0.001748 0.001192
Nuclear Periphery Foci 0.040942 0.000986 0.000472 0.003431 0.000327 0.000223 0.002308 0.002358 0.001391 0.000327 0.000558 0.002705
Nucleolus 0.017868 0.004647 0.000333 0.000651 0.000759 0.001321 0.000902 0.000783 0.001207 0.001771 0.000360 0.000740
Nucleus 0.064086 0.066375 0.471614 0.179458 0.157529 0.101286 0.418196 0.088296 0.155081 0.096568 0.469108 0.117809
Peroxisomes 0.005696 0.045222 0.000090 0.008642 0.006620 0.016686 0.000498 0.015708 0.006595 0.020542 0.000109 0.013420
Vacuole 0.076956 0.078247 0.030871 0.181451 0.044628 0.075626 0.165444 0.180384 0.045475 0.075981 0.037185 0.180729
Vacuole Periphery 0.017303 0.004100 0.000133 0.000788 0.001430 0.002243 0.000247 0.008834 0.001846 0.002494 0.000139 0.006229

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 2.29 3.00 -0.66 -2.51 -3.04 -0.72 -0.61 -4.51 -4.55 -4.29 -0.61 1.68 -4.37 -4.34 -4.98
Bud Neck -7.84 2.42 0.29 8.53 -5.15 -11.08 9.46 2.72 14.73 -9.47 -12.39 8.57 3.48 17.52 -9.09
Bud Site 2.03 2.87 2.11 0.49 -7.22 -9.69 0.39 -12.18 -7.33 -11.49 -7.16 1.43 -11.57 -6.95 -13.37
Cell Periphery 1.62 3.14 2.60 2.56 -7.64 -1.64 -4.98 -0.88 -0.73 -0.16 -2.14 5.13 -0.90 -0.57 -1.40
Cytoplasm 0.12 -2.58 -1.34 -4.17 4.96 6.75 8.57 10.22 4.90 -3.72 8.45 7.86 11.54 4.25 4.83
Cytoplasmic Foci -3.19 5.19 3.99 21.00 -12.58 -1.15 24.46 26.70 34.43 -4.34 -2.26 39.91 29.01 41.51 -22.84
Eisosomes -3.51 4.13 0.15 4.23 -11.55 0.48 0.59 5.66 12.56 6.65 0.01 7.69 5.11 12.02 -15.10
Endoplasmic Reticulum 2.18 2.01 1.62 -8.47 -6.21 2.87 -5.65 -2.99 -11.50 4.98 3.20 -3.77 -4.31 -13.98 -1.20
Endosome -1.01 4.13 3.53 9.45 -7.17 -6.87 4.61 -2.57 3.67 -6.88 -8.86 11.52 -0.17 9.31 -13.84
Golgi 1.28 2.57 2.49 5.38 -3.42 -5.74 7.04 -1.75 2.19 -4.83 -5.68 7.39 -0.02 4.83 -5.22
Lipid Particles -2.30 3.76 2.14 4.42 -6.99 2.60 4.31 8.21 7.13 3.12 1.52 10.70 7.99 8.05 -10.16
Mitochondria -1.48 1.77 1.63 6.75 -1.18 -3.69 5.48 2.94 7.94 -3.53 -4.34 5.36 3.63 10.35 -3.23
Mitotic Spindle 1.80 1.88 0.87 -4.72 -5.58 -5.15 1.62 -12.89 -10.83 -13.30 -4.43 -1.38 -13.57 -11.28 -13.38
None -1.45 -1.59 -0.61 1.12 0.94 -0.18 0.99 -0.08 0.10 -1.08 -0.89 -3.80 -0.55 0.39 3.05
Nuclear Periphery 1.41 -1.03 -0.39 -4.34 2.93 2.20 -8.42 -12.89 -14.04 2.73 0.95 -27.97 -16.42 -16.59 6.67
Nuclear Periphery Foci 2.31 2.33 2.16 -4.82 -6.15 2.57 -6.50 -4.81 -5.07 1.40 2.18 1.25 -2.09 -7.60 -6.03
Nucleolus 1.32 1.80 1.76 3.24 -3.11 -4.30 -0.00 -2.07 1.05 -1.88 -1.80 2.88 0.65 3.67 -5.27
Nucleus -0.10 -18.36 -5.16 -11.92 30.16 10.44 -9.60 6.97 -2.16 11.34 11.18 -46.82 2.75 -8.50 50.87
Peroxisomes -7.55 3.91 -0.47 7.42 -5.00 -8.44 9.74 -3.02 3.88 -8.61 -10.88 10.61 -2.51 7.74 -10.22
Vacuole 0.29 1.41 -9.38 -18.01 -21.87 -10.35 -9.19 -30.02 -25.48 -1.54 -10.60 -6.42 -36.90 -31.72 -32.34
Vacuole Periphery 3.06 4.00 3.91 6.50 -4.60 -3.11 6.27 -2.90 -2.06 -4.24 -2.24 7.62 -1.71 -0.79 -4.51
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR); glutathione transferase involved in cell-surface biosynthesis and architecture; catalyzes glutathione (GSH)-dependent reduction of GS-trichloro-p-hydroquinone to trichloro-p-hydroquinone; expression upregulated upon exposure to genotoxic agents, such as methyl methanesulfonate, cisplatin and bleomycin; not an essential gene; similar to YGR154C; green fluorescent protein (GFP)-fusion protein localizes to cytoplasm
Localization
Cell Percentages cytoplasm (31%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Ecm4

Ecm4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ecm4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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