Standard name
Human Ortholog
Description Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.06 0 0 0.07 0.05 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0.05 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.1 0.05 0.09 0.12 0.14 0.15 0.24 0.23 0.27 0.21 0.21 0 0 0 0.05 0.06 0.09 0 0 0 0 0 0
Endoplasmic Reticulum 0 0.07 0 0 0 0.09 0.05 0.08 0.09 0 0.05 0 0.1 0.09 0 0 0.07 0.05 0 0 0 0 0 0
Endosome 0.06 0 0.12 0.13 0.17 0.09 0.09 0.17 0.09 0.21 0.08 0.07 0.09 0.11 0.16 0.2 0.22 0.28 0.34 0.35 0.39 0.43 0.4 0.42
Golgi 0.44 0.28 0.22 0.29 0.12 0.05 0 0 0 0 0 0 0.38 0.51 0.49 0.36 0.3 0.31 0.43 0.28 0.34 0.33 0.28 0.28
Mitochondria 0.27 0.16 0.62 0.52 0.42 0.62 0.65 0.31 0.53 0.37 0.63 0.68 0.14 0.11 0.06 0.14 0.12 0.11 0 0 0.07 0 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0.06 0.09 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.61 0.61 0.39 0.34 0.37 0.21 0.19 0.25 0.21 0.26 0.21 0.17 0.49 0.38 0.5 0.46 0.44 0.42 0.16 0.28 0.15 0.16 0.2 0.23
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 6 12 2 4 8 13 9 17 29 10 7 5 24 31 11 6 14 8 1 7 3 6 6 5
Bud 0 3 2 5 8 20 30 20 31 45 48 70 3 4 5 0 1 1 0 3 0 1 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 1 3 6 6 10 7 6 9 0 1 2 1 1 0 0 0 0 0 0 0
Cytoplasm 4 42 14 45 96 126 157 206 209 240 160 254 19 14 14 9 12 14 0 6 1 1 2 1
Endoplasmic Reticulum 6 29 9 19 33 76 52 65 81 32 36 50 51 48 21 7 13 8 0 4 1 2 9 4
Endosome 10 14 35 63 137 84 102 147 81 190 61 80 46 58 128 34 42 41 62 182 130 174 202 233
Golgi 75 118 67 145 95 42 31 37 23 16 10 12 188 277 389 60 56 46 80 148 113 134 138 152
Mitochondria 47 68 187 257 330 553 701 260 484 327 483 818 67 61 50 23 22 16 6 17 24 17 27 20
Nucleus 0 1 0 0 1 5 3 7 2 2 4 2 2 0 0 1 0 0 0 1 0 0 1 1
Nuclear Periphery 0 0 0 4 3 7 14 5 4 0 2 6 4 5 3 2 1 2 2 1 1 0 2 1
Nucleolus 4 10 5 5 13 26 34 21 11 10 7 18 2 5 5 11 12 14 0 0 0 0 2 0
Peroxisomes 0 0 0 0 1 2 0 0 2 0 1 3 0 2 1 0 1 0 0 0 2 1 2 0
SpindlePole 0 0 1 0 0 10 6 12 3 21 6 7 5 5 4 7 7 6 0 1 0 0 1 0
Vac/Vac Membrane 104 261 119 170 289 188 203 207 190 236 160 207 242 204 399 78 83 62 30 145 50 63 100 129
Unique Cell Count 171 427 304 497 784 887 1082 842 911 895 772 1199 489 539 795 169 187 148 185 522 330 408 500 554
Labelled Cell Count 256 558 441 717 1015 1155 1348 1010 1160 1136 991 1542 653 715 1032 239 265 218 185 522 330 408 500 554


Early Golgi, Endosome, Late Golgi, Punctate Nuclear

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.3 13.3 8.4 8.6 7.9 6.8 6.2 6.9 6.6 6.2 6.2 5.8 11.0 11.2 11.5 11.8 11.7 11.3 12.8 12.5 12.8
Std Deviation (1e-4) 2.2 3.1 1.7 1.6 1.6 1.5 1.3 1.4 1.4 1.4 1.3 1.2 1.8 1.9 1.7 3.4 3.1 3.6 2.1 2.4 2.3
Intensity Change (Log2) – – – 0.04 -0.09 -0.3 -0.43 -0.28 -0.34 -0.44 -0.43 -0.53 0.4 0.42 0.46 0.5 0.49 0.44 0.62 0.58 0.62


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 1.6 2.4 0 0 0 3.3 3.7 0 0 4.1 0
Bud 0 0 1.8 2.2 1.9 2.5 3.4 3.9 3.8 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 2.3 3.8 4.5 4.6 7.5 7.2 8.2 6.5 6.7 -0.5 -1.6 -2.7 0.3 0.9 2.0
Endoplasmic Reticulum 0.6 1.0 3.3 1.4 2.9 3.4 0.5 1.3 1.0 3.9 3.3 -0.3 0.7 2.1 1.3
Endosome 0.5 2.4 -1.0 -1.1 2.4 -1.3 3.7 -1.9 -2.8 -1.0 -0.3 1.9 2.5 3.2 4.3
Golgi 2.2 -4.1 -9.0 -11.5 -9.2 -11.2 -12.0 -11.9 -14.7 4.8 8.3 8.1 3.2 2.0 2.1
Mitochondria -2.7 -5.8 0.3 1.1 -9.4 -2.5 -7.6 0.3 2.2 -14.0 -15.4 -19.9 -10.0 -10.8 -10.2
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 1.2 1.4 0.9 0 0 0 0 0 0 0 2.8 2.8 3.9
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 2.3 0 0 0 0 0 0 0 0
Vacuole -1.4 -0.7 -6.2 -7.4 -4.8 -6.3 -4.2 -6.2 -8.3 2.8 -0.4 3.3 1.5 1.1 0.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.8622 8.6133 7.2731 6.6654 6.1511 7.5843 6.2442 8.4721 7.6147 7.8563 6.6407 7.6419 4.4448 7.0867 6.5445 5.1833 4.3183 6.0751
Actin 0.0062 0.0031 0.0054 0.0039 0.0006 0.0017 0.0094 0.0001 0.0048 0.001 0.0037 0.0009 0.0065 0.0001 0.0032 0.0001 0.0485 0.0003
Bud 0.0073 0.0048 0.0085 0.0015 0.0002 0.0046 0.0003 0.0001 0.0001 0.0003 0.0002 0 0.0001 0.0001 0.0001 0 0.0006 0
Bud Neck 0.0018 0.0003 0.0015 0.0036 0.0002 0.0004 0.0003 0.0001 0.0002 0.0014 0.0001 0.0001 0.0003 0.0001 0.0002 0.0001 0.0015 0.0001
Bud Periphery 0.0013 0.0013 0.0029 0.0012 0.0002 0.0009 0.0005 0.0001 0.0001 0.0004 0.0002 0 0.0001 0.0001 0.0001 0 0.0009 0
Bud Site 0.0037 0.0075 0.0092 0.0021 0.0011 0.0005 0.0017 0.0001 0.0007 0.0271 0.0003 0.0001 0.0002 0.0001 0.0009 0 0.0045 0
Cell Periphery 0.0003 0.0005 0.0011 0.0009 0.0001 0.0002 0.0002 0.0001 0 0.0008 0.0001 0 0.0001 0 0.0001 0 0.0003 0.0001
Cytoplasm 0.0051 0.0097 0.0127 0.0066 0.0009 0.0112 0.0052 0.0017 0.0018 0.0014 0.003 0.0008 0.0018 0.0012 0.0012 0.0006 0.0013 0.0005
Cytoplasmic Foci 0.0689 0.0703 0.0969 0.1043 0.0501 0.0684 0.0451 0.0355 0.0374 0.0302 0.043 0.0278 0.0274 0.031 0.0239 0.0213 0.0304 0.0213
Eisosomes 0.0001 0 0.0002 0.0002 0 0 0.0001 0 0 0 0.0001 0 0.001 0 0.0002 0 0.0007 0
Endoplasmic Reticulum 0.0021 0.0012 0.0012 0.0014 0.0006 0.0011 0.0015 0.0016 0.0011 0.0009 0.0053 0.0012 0.002 0.0008 0.0011 0.0007 0.0036 0.0011
Endosome 0.4886 0.5051 0.4413 0.4409 0.5527 0.4721 0.4907 0.5359 0.4918 0.5268 0.4498 0.3997 0.4544 0.5082 0.4347 0.5581 0.4853 0.3683
Golgi 0.2924 0.3115 0.3115 0.2659 0.3013 0.359 0.3176 0.3647 0.3823 0.3393 0.3654 0.4997 0.3547 0.3821 0.4379 0.3235 0.3102 0.506
Lipid Particles 0.0202 0.0051 0.0094 0.0227 0.0288 0.0113 0.0265 0.0032 0.0084 0.0035 0.0282 0.011 0.023 0.0127 0.0146 0.0124 0.0267 0.0228
Mitochondria 0.0375 0.0169 0.026 0.0655 0.0129 0.0236 0.0509 0.017 0.0197 0.0057 0.0266 0.0156 0.0275 0.0123 0.0087 0.0035 0.0216 0.0176
None 0.0015 0.0053 0.0049 0.0042 0.0001 0.001 0.0005 0 0.0002 0.0001 0.0034 0 0.0104 0 0.001 0 0.0012 0
Nuclear Periphery 0.002 0.0006 0.002 0.0015 0.0004 0.0005 0.0014 0.0006 0.0012 0.0005 0.0046 0.0023 0.0045 0.0005 0.0014 0.0007 0.0077 0.0043
Nucleolus 0.0036 0.0005 0.0068 0.0102 0.0003 0.0014 0.0002 0 0.0001 0.0003 0.0002 0 0.0007 0 0.0001 0 0.0009 0
Nucleus 0.0033 0.0017 0.0053 0.002 0.0001 0.0011 0.0007 0.0001 0.0001 0.0003 0.0017 0.0001 0.0012 0.0001 0.0001 0.0001 0.0016 0.0001
Peroxisomes 0.0203 0.0049 0.0075 0.0137 0.0116 0.0051 0.0038 0.0003 0.0062 0.0006 0.0175 0.002 0.0088 0.0004 0.0007 0.0005 0.0114 0.0016
Punctate Nuclear 0.0017 0.0001 0.0009 0.0015 0.0001 0.0002 0.0003 0 0.0007 0.0001 0.0008 0.0001 0.0012 0 0.0003 0 0.0026 0.0001
Vacuole 0.0133 0.0245 0.0229 0.0259 0.0252 0.0133 0.0169 0.0137 0.0183 0.0258 0.0137 0.0108 0.031 0.0211 0.0263 0.0333 0.0183 0.0152
Vacuole Periphery 0.0185 0.0251 0.0218 0.0202 0.0126 0.0225 0.0262 0.0252 0.0246 0.0333 0.0318 0.0277 0.0429 0.0289 0.0432 0.0451 0.0202 0.0405

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 31.0128 31.1282 20.933 28.3511 14.1086 21.7514 28.5231 38.8342 28.0677 34.7694
Translational Efficiency 1.0529 0.9083 1.1853 0.8607 1.8084 1.6523 1.2422 0.633 1.1036 0.9753

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
87 1509 172 1054 1629 794 505 2406 1716 2303 677 3460

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1037.10 980.62 1540.09 1176.23 1049.80 1071.57 1345.93 1189.56 1049.16 1011.98 1395.26 1185.50
Standard Deviation 143.18 184.47 188.56 180.93 164.43 128.16 188.11 176.71 163.44 172.71 206.33 178.12
Intensity Change Log 2 — -0.080789 0.570460 0.181615 — 0.029612 0.358489 0.180314 — -0.024197 0.467720 0.180961

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000656 0.002022 0.002417 0.001145 0.000294 0.000164 0.003557 0.000737 0.000313 0.001381 0.003267 0.000861
Bud Neck 0.000675 0.000274 0.004873 0.000711 0.000647 0.000254 0.000748 0.000332 0.000648 0.000267 0.001796 0.000447
Bud Site 0.003386 0.002270 0.003416 0.007377 0.002071 0.001071 0.002136 0.002783 0.002137 0.001857 0.002461 0.004183
Cell Periphery 0.000878 0.000110 0.000356 0.000120 0.000272 0.000178 0.000194 0.000090 0.000303 0.000133 0.000235 0.000099
Cytoplasm 0.000637 0.000733 0.000247 0.003045 0.000598 0.000344 0.000400 0.001748 0.000600 0.000599 0.000361 0.002143
Cytoplasmic Foci 0.067362 0.116446 0.051250 0.118791 0.069069 0.067530 0.057120 0.081144 0.068982 0.099581 0.055628 0.092613
Eisosomes 0.000037 0.000042 0.000030 0.000021 0.000021 0.000018 0.000037 0.000012 0.000021 0.000034 0.000036 0.000015
Endoplasmic Reticulum 0.005470 0.000571 0.001159 0.000676 0.000699 0.000888 0.000783 0.000311 0.000941 0.000680 0.000878 0.000422
Endosome 0.257820* 0.258275* 0.161700 0.250604* 0.196635 0.231985* 0.160934 0.306167* 0.199738 0.249211* 0.161129 0.289241*
Golgi 0.284714* 0.556503* 0.178769* 0.430616* 0.534843* 0.344820* 0.515361* 0.393518* 0.522161* 0.483521* 0.429846* 0.404819*
Lipid Particles 0.000833 0.012443 0.013299 0.003835 0.001522 0.002589 0.007455 0.002949 0.001487 0.009046 0.008940 0.003219
Mitochondria 0.034574 0.013772 0.008279 0.008972 0.024771 0.041163 0.010098 0.018088 0.025268 0.023216 0.009636 0.015311
Mitotic Spindle 0.004447 0.000419 0.002942 0.016461 0.000752 0.001158 0.001228 0.006643 0.000940 0.000674 0.001664 0.009633
None 0.000057 0.000038 0.000066 0.000036 0.000052 0.000063 0.000058 0.000088 0.000052 0.000047 0.000060 0.000072
Nuclear Periphery 0.000211 0.000062 0.005921 0.000379 0.000175 0.000768 0.000739 0.000581 0.000177 0.000305 0.002056 0.000520
Nuclear Periphery Foci 0.000655 0.000478 0.016013 0.002049 0.000489 0.002366 0.002168 0.003195 0.000498 0.001129 0.005686 0.002846
Nucleolus 0.000053 0.000025 0.000242 0.000038 0.000022 0.000093 0.000068 0.000072 0.000024 0.000048 0.000113 0.000062
Nucleus 0.000098 0.000027 0.000148 0.000049 0.000265 0.000077 0.000023 0.000057 0.000257 0.000044 0.000054 0.000054
Peroxisomes 0.002508 0.002082 0.003862 0.003630 0.000436 0.001670 0.001461 0.000928 0.000541 0.001940 0.002071 0.001752
Vacuole 0.139840 0.016241 0.349069* 0.100924 0.068010 0.133097 0.153230 0.108225 0.071652 0.056529 0.202985* 0.106001
Vacuole Periphery 0.195089* 0.017166 0.195944* 0.050519 0.098356 0.169705* 0.082200 0.072331 0.103260* 0.069757 0.111098* 0.065687

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.42 -1.33 -1.17 1.83 0.97 1.84 -2.83 -1.14 -1.49 2.33 -3.81 -3.22 -1.98 1.32 2.51
Bud Neck 2.04 -4.63 -0.27 -5.03 4.66 1.01 -0.25 0.78 -1.44 3.22 1.03 -2.58 0.51 -3.44 5.26
Bud Site 1.24 -0.03 -3.13 -4.58 -3.17 3.23 -0.18 -1.73 -4.84 -1.55 0.75 -0.82 -4.36 -5.07 -3.64
Cell Periphery 2.10 1.40 2.07 -0.63 3.33 1.00 0.84 1.97 3.64 6.37 1.89 0.74 2.27 2.76 6.22
Cytoplasm -0.48 2.73 -4.15 -3.98 -4.74 2.26 1.66 -3.73 -4.60 -4.40 -0.03 2.23 -5.53 -5.43 -6.42
Cytoplasmic Foci -5.04 1.43 -5.02 -0.42 -8.85 0.39 2.73 -4.08 -3.39 -5.39 -10.25 3.47 -8.43 2.30 -9.53
Eisosomes -0.56 0.75 1.96 5.91 1.44 1.01 -3.46 4.85 3.49 5.28 -4.82 -3.48 3.88 8.18 5.29
Endoplasmic Reticulum 1.62 1.42 1.58 -0.89 1.89 -0.83 -0.61 4.15 2.67 4.11 1.36 0.31 2.87 2.82 4.19
Endosome -0.02 4.08 0.37 0.99 -6.31 -4.39 4.33 -17.09 -8.80 -16.87 -8.40 5.21 -15.68 -6.88 -17.49
Golgi -9.11 3.19 -4.71 11.51 -13.60 16.34 1.33 15.76 -4.30 8.51 4.37 6.72 14.14 10.56 2.01
Lipid Particles -8.63 -4.73 -3.53 5.57 3.44 -1.87 -4.82 -2.83 -0.64 3.65 -8.03 -6.45 -3.58 6.14 4.92
Mitochondria 2.37 2.93 2.93 2.38 -0.25 -3.86 5.47 2.81 5.77 -3.50 0.81 6.43 4.59 4.08 -3.11
Mitotic Spindle 1.11 0.41 -2.80 -6.39 -5.25 -0.75 -0.98 -6.11 -5.72 -5.79 0.62 -1.47 -8.19 -9.00 -7.82
None 1.49 -0.58 1.70 0.38 3.40 -2.14 -1.05 -0.85 -0.59 -0.70 1.13 -1.48 -0.68 -0.86 -0.41
Nuclear Periphery 3.20 -5.19 -2.41 -5.70 5.03 -2.20 -6.39 -6.82 0.67 1.55 -1.33 -6.27 -7.19 -2.15 5.09
Nuclear Periphery Foci 0.94 -3.57 -2.86 -3.29 3.21 -1.80 -6.84 -5.31 -0.73 -1.87 -1.70 -4.58 -6.11 -3.31 2.36
Nucleolus 1.29 -3.34 0.61 -1.32 3.75 -1.56 -0.97 -2.69 0.35 -0.14 -1.40 -2.32 -2.81 -0.78 1.20
Nucleus 1.88 -0.93 0.83 -2.07 1.92 0.81 1.04 0.88 0.51 -2.21 0.96 0.92 0.89 -1.04 -0.41
Peroxisomes 0.47 -0.88 -1.11 -2.41 0.16 -2.14 -2.94 -4.04 1.26 1.49 -4.70 -3.62 -6.10 0.54 0.72
Vacuole 7.74 -9.19 2.26 -17.99 14.56 -10.74 -9.32 -9.69 3.93 4.82 4.13 -14.88 -9.18 -14.48 11.00
Vacuole Periphery 7.38 -0.03 5.97 -10.46 10.50 -9.21 2.57 6.03 13.59 1.79 7.08 -1.18 9.05 1.22 7.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Integral membrane protein; localized to late Golgi vesicles along with the v-SNARE Tlg2p; required for asymmetric localization of Kar9p during mitosis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
Localization
Cell Percentages Golgi (13%), vacuole (4%), mixed (40%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Tvp38

Tvp38


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Tvp38-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available