Standard name
Human Ortholog
Description Integral membrane peptide transporter; mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0.09 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0.07 0.11 0 0.06 0.05 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0.08 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.13 0.38 0.24 0.3 0.26 0.28 0.26 0.22 – 0.24 0.26 0.25 0.89 0.89 0.94 0.24 0.25 0.19 0 0.11 0 0.08 0.13 0.19
Endoplasmic Reticulum 0 0 0 0.12 0.07 0.05 0 0.05 – 0 0.05 0 0 0 0 0 0.06 0.06 0.07 0.05 0.05 0 0 0
Endosome 0.07 0.08 0.08 0.07 0 0 0 0 – 0 0 0 0 0 0 0.08 0 0.09 0 0 0 0 0.05 0.06
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0.06 0.11 0 0 0 0 0 – 0.06 0.06 0 0 0 0 0.1 0.06 0.06 0 0 0 0 0 0
Nucleus 0.14 0.12 0.18 0.12 0.1 0.12 0.18 0.18 – 0.17 0.09 0.14 0 0 0 0.24 0.25 0.23 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.64 0.38 0.53 0.37 0.59 0.55 0.55 0.6 – 0.57 0.56 0.61 0.08 0.07 0 0.47 0.46 0.59 0.72 0.62 0.76 0.67 0.62 0.55
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 3 1 1 14 6 13 8 15 – 10 7 7 5 6 2 0 0 1 2 1 5 3 3 5
Bud 1 0 2 6 1 5 6 16 – 8 9 7 1 1 1 0 0 0 17 17 11 17 17 10
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 9 11 12 0 0 0 1 4 2 0 3 5
Bud Site 1 1 0 0 2 2 0 1 – 0 0 0 1 1 1 0 0 0 – – – – – –
Cell Periphery 4 2 2 12 2 6 8 8 – 2 5 7 1 1 2 1 0 1 0 0 0 4 1 1
Cytoplasm 29 52 62 48 65 98 111 109 – 82 61 76 753 753 785 36 17 26 3 17 5 25 43 70
Endoplasmic Reticulum 5 6 7 19 17 18 17 23 – 12 11 5 5 5 5 6 4 8 17 7 14 9 11 10
Endosome 16 11 21 11 5 15 11 6 – 7 9 4 15 16 7 13 3 12 7 3 7 13 16 23
Golgi 6 1 2 1 7 2 2 2 – 5 4 4 0 0 0 5 0 2 1 0 3 0 3 4
Mitochondria 16 8 27 1 2 13 18 15 – 20 15 13 1 1 0 16 4 8 4 1 7 12 12 14
Nucleus 32 16 45 19 26 41 77 89 – 60 22 43 7 7 0 37 17 31 2 0 1 1 1 2
Nuclear Periphery 0 3 0 2 1 0 2 2 – 2 1 1 0 0 0 2 1 1 2 1 0 0 4 0
Nucleolus 4 3 2 2 2 6 19 11 – 19 8 11 0 0 0 2 3 6 0 0 0 0 0 1
Peroxisomes 0 0 2 1 1 2 8 1 – 1 0 0 0 0 0 1 1 1 1 0 0 0 0 2
SpindlePole 5 3 4 2 0 4 6 3 – 3 0 1 23 23 18 8 3 4 4 3 2 6 8 9
Vac/Vac Membrane 141 51 136 58 147 195 238 302 – 199 130 188 64 61 24 72 32 80 175 100 218 203 216 203
Unique Cell Count 221 136 255 158 248 355 433 502 347 232 310 844 848 834 153 69 135 245 162 286 305 350 370
Labelled Cell Count 263 158 313 196 284 420 531 603 430 282 367 885 886 857 199 85 181 245 162 286 305 350 370


Cell Periphery, Vacuole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 11.6 8.5 8.1 12.0 13.5 13.5 16.3 17.5 – 22.6 24.3 25.8 5.2 5.2 5.2 10.4 11.1 12.4 7.6 6.9 6.9
Std Deviation (1e-4) 8.0 7.3 4.6 7.4 8.8 9.5 11.0 10.6 – 13.6 14.8 14.9 1.0 1.0 1.5 7.5 9.2 8.0 5.8 2.7 3.5
Intensity Change (Log2) – – – 0.58 0.74 0.75 1.02 1.12 – 1.49 1.6 1.68 -0.62 -0.62 -0.63 0.37 0.46 0.62 -0.08 -0.21 -0.23


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 4.5 0 2.7 0 2.3 – 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 2.1 – 0 2.3 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 3.7 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 0.5 0.9 0.4 -0.8 – -0.2 0.5 0.1 20.7 20.6 23.5 -0.2 0.1 -1.1
Endoplasmic Reticulum 3.8 2.2 1.4 0.8 1.2 – 0.5 1.2 -0.9 0 0 0 0 0 1.6
Endosome -0.5 -3.1 -2.1 -3.4 -4.9 – -3.6 -2.0 -4.0 -5.1 -4.9 -6.5 0.1 -1.1 0.2
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria -3.9 -4.7 -3.4 -3.3 -4.3 – -2.2 -1.6 -2.9 -9.3 -9.3 -9.5 0 -1.2 -1.5
Nucleus -1.5 -2.3 -2.1 0 0 – -0.1 -2.6 -1.2 -11.1 -11.1 -12.4 1.6 1.3 1.3
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 2.7 0 – 3.1 0 2.2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 1.0 1.0 0.6 0 0 0
Vacuole -3.3 1.3 0.4 0.4 1.8 – 1.0 0.6 1.7 -16.6 -16.9 -19.9 -1.2 -1.0 1.1

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 1.2126 0.7537 0.6105 0.055 1.3948 0.6388 2.0735 1.8242 1.8525 1.301 1.7377 2.1266 2.5389 2.6803 2.0178 1.54 1.3019 1.8253
Actin 0.0436 0.0028 0.0161 0.0249 0.0078 0.0031 0.0396 0.0005 0.0153 0.001 0.0297 0.0153 0.0889 0.0001 0.0063 0.0003 0 0.0075
Bud 0.0016 0.0069 0.0019 0.0013 0.0003 0.0008 0.0029 0.0078 0.0026 0.0004 0.0016 0.0002 0.0019 0.0025 0.0005 0.0013 0.0001 0.0003
Bud Neck 0.0129 0.0016 0.0062 0.0015 0.0004 0.0006 0.0097 0.0015 0.0042 0.0001 0.0003 0.0104 0.002 0.0011 0.0009 0 0.0004 0.0038
Bud Periphery 0.0054 0.007 0.0052 0.0021 0.0003 0.0026 0.0057 0.0096 0.0052 0.0038 0.0069 0.0006 0.0084 0.0041 0.0007 0.0098 0.0001 0.001
Bud Site 0.0088 0.0147 0.0068 0.0112 0.0028 0.0002 0.0262 0.0121 0.0134 0.0003 0.0002 0.0002 0.0042 0.0055 0.0035 0.0003 0.0012 0.0003
Cell Periphery 0.0167 0.0055 0.0133 0.0007 0.0005 0.0004 0.0096 0.0022 0.0088 0.0012 0.0004 0.0009 0.0211 0.0149 0.0044 0.0018 0.0002 0.0017
Cytoplasm 0.0756 0.1144 0.0756 0.0772 0.1641 0.0499 0.0894 0.1367 0.0713 0.0652 0.1088 0.1462 0.1066 0.1545 0.1249 0.0395 0.1533 0.2636
Cytoplasmic Foci 0.061 0.0164 0.0196 0.0206 0.0556 0.0202 0.0429 0.0181 0.0312 0.007 0.0249 0.0232 0.0063 0.0119 0.0247 0.0195 0.0366 0.0247
Eisosomes 0.0005 0.0002 0.0005 0.0005 0 0.0001 0.0003 0.0002 0.0003 0.0001 0.0002 0.0001 0.0004 0.0002 0.0002 0.0005 0 0
Endoplasmic Reticulum 0.0099 0.0065 0.0029 0.0101 0.0043 0.0012 0.0247 0.0019 0.0126 0.0022 0.0017 0.0019 0.0307 0.0035 0.0015 0.0087 0.001 0.0125
Endosome 0.076 0.0344 0.0504 0.0835 0.1077 0.0765 0.0452 0.018 0.0138 0.0248 0.1345 0.0387 0.0187 0.0132 0.0232 0.0632 0.0606 0.0666
Golgi 0.0096 0.0011 0.0053 0.0082 0.006 0.0026 0.0166 0.0016 0.0043 0.0011 0.01 0.002 0.011 0.0005 0.001 0.0086 0.001 0.0047
Lipid Particles 0.0232 0.0014 0.0113 0.019 0.0452 0.0133 0.0252 0.0037 0.0156 0.0111 0.0086 0.0087 0.005 0.0166 0.0033 0.0064 0.003 0.0188
Mitochondria 0.0067 0.0011 0.0063 0.006 0.0006 0.0036 0.0051 0.001 0.0017 0.0017 0.0023 0.0011 0.0066 0.0007 0.0005 0.2068 0.0005 0.001
None 0.5307 0.6701 0.7215 0.5704 0.3365 0.7313 0.569 0.7035 0.7796 0.7746 0.5451 0.6732 0.5335 0.666 0.7643 0.5862 0.666 0.5399
Nuclear Periphery 0.0175 0.0034 0.0038 0.0066 0.0037 0.0033 0.0028 0.0007 0.0013 0.0009 0.0018 0.0006 0.014 0.0013 0.0009 0.0035 0.0005 0.0014
Nucleolus 0.0016 0.0024 0.0014 0.0031 0.0022 0.0011 0.0009 0.0011 0.0006 0.0002 0.0003 0.0012 0.0101 0.0019 0.0009 0.0007 0.0002 0.0002
Nucleus 0.0105 0.0088 0.0058 0.0045 0.0047 0.0017 0.002 0.0043 0.0012 0.0007 0.0009 0.0012 0.0255 0.0025 0.0009 0.0012 0.0004 0.0007
Peroxisomes 0.0233 0.0005 0.0041 0.0037 0.0136 0.0076 0.0162 0.0137 0.0094 0.0576 0.0016 0.0027 0.0089 0.0003 0.0028 0.0016 0.0002 0.0028
Punctate Nuclear 0.0187 0.0025 0.0037 0.005 0.0143 0.0022 0.0017 0.0033 0.0023 0.0004 0.0004 0.0005 0.0009 0.0011 0.0017 0.0002 0.0002 0.0004
Vacuole 0.0372 0.0937 0.0355 0.1306 0.2163 0.0653 0.0617 0.0572 0.0049 0.0432 0.1065 0.0661 0.0879 0.0916 0.032 0.0266 0.0722 0.044
Vacuole Periphery 0.009 0.0046 0.0028 0.0093 0.0131 0.0123 0.0026 0.0012 0.0005 0.0026 0.0134 0.0049 0.0072 0.0062 0.0011 0.0133 0.0022 0.004

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 90.1175 122.8874 163.7327 238.6338 212.2946 61.0628 99.6772 122.0647 136.9668 149.0274
Translational Efficiency 1.2803 1.2977 1.4619 1.3287 1.3629 1.5117 1.1825 1.1999 1.3388 1.1755

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✔
Translational Efficiency ✔

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
128 173 255 89 109 1850 1730 1624 237 2023 1985 1713

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1030.69 796.28 874.61 961.30 704.70 819.65 865.42 847.95 880.76 817.65 866.60 853.84
Standard Deviation 200.56 232.51 109.16 150.24 91.94 182.38 177.25 222.24 228.05 187.30 170.06 220.52
Intensity Change Log 2 — -0.372263 -0.236899 -0.100552 — 0.217999 0.296391 0.266970 — -0.102895 0.003852 0.060132

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003911 0.003959 0.004915 0.019614 0.000089 0.001394 0.013344 0.008745 0.002153 0.001613 0.012261 0.009310
Bud Neck 0.034393 0.067678 0.010584 0.040087 0.036717 0.082831 0.046605 0.040109 0.035462 0.081535 0.041978 0.040107
Bud Site 0.087876 0.060300 0.032889 0.154650* 0.009896 0.085031 0.145110* 0.096713 0.052012 0.082916 0.130693* 0.099723
Cell Periphery 0.037670 0.028616 0.005378 0.050995 0.003416 0.040473 0.046410 0.021229 0.021916 0.039459 0.041139 0.022776
Cytoplasm 0.127440* 0.247939* 0.283517* 0.187720* 0.219137* 0.187907* 0.391758* 0.396685* 0.169613* 0.193041* 0.377853* 0.385828*
Cytoplasmic Foci 0.052245 0.213793* 0.040091 0.025273 0.194265* 0.073468 0.019724 0.031257 0.117562 0.085468 0.022340 0.030946
Eisosomes 0.000279 0.000805 0.000568 0.005139 0.000351 0.000663 0.002849 0.002085 0.000312 0.000675 0.002556 0.002243
Endoplasmic Reticulum 0.021444 0.006266 0.014237 0.023015 0.005253 0.009395 0.008615 0.003486 0.013998 0.009127 0.009337 0.004500
Endosome 0.060433 0.030281 0.009294 0.007063 0.052772 0.041735 0.003799 0.008269 0.056910 0.040756 0.004505 0.008207
Golgi 0.017605 0.003105 0.000550 0.001961 0.000890 0.005265 0.000443 0.002317 0.009918 0.005080 0.000456 0.002298
Lipid Particles 0.003425 0.004838 0.006275 0.005480 0.012222 0.004786 0.003124 0.004073 0.007471 0.004790 0.003529 0.004146
Mitochondria 0.006435 0.003766 0.000305 0.000163 0.004876 0.007801 0.000669 0.004136 0.005718 0.007456 0.000622 0.003930
Mitotic Spindle 0.005347 0.000996 0.000140 0.009306 0.000101 0.002297 0.002963 0.007398 0.002934 0.002186 0.002601 0.007497
None 0.000058 0.000589 0.003428 0.000833 0.000896 0.001424 0.001648 0.004286 0.000444 0.001353 0.001876 0.004107
Nuclear Periphery 0.002831 0.000239 0.001437 0.000377 0.000670 0.000293 0.000539 0.000387 0.001837 0.000289 0.000654 0.000386
Nuclear Periphery Foci 0.003183 0.004713 0.005310 0.003101 0.000295 0.000355 0.000990 0.000685 0.001855 0.000728 0.001545 0.000810
Nucleolus 0.000376 0.000919 0.001096 0.000098 0.001648 0.000882 0.000189 0.000572 0.000961 0.000885 0.000306 0.000548
Nucleus 0.009575 0.040828 0.425089* 0.054072 0.100826 0.029612 0.168667* 0.133835* 0.051543 0.030571 0.201608* 0.129690
Peroxisomes 0.003408 0.018871 0.000784 0.005772 0.004482 0.006591 0.001458 0.002304 0.003902 0.007642 0.001372 0.002484
Vacuole 0.507018* 0.257215* 0.153794 0.405141* 0.347132* 0.410683* 0.140504 0.230065* 0.433484* 0.397559* 0.142211 0.239161*
Vacuole Periphery 0.015047 0.004283 0.000320 0.000141 0.004066 0.007114 0.000592 0.001366 0.009996 0.006872 0.000557 0.001302

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.15 -0.05 -2.40 -2.05 -2.41 -4.37 -10.24 -8.50 -6.48 2.99 0.43 -7.26 -5.36 -6.62 2.26
Bud Neck -2.67 2.96 0.26 2.76 -2.30 -4.91 -0.39 0.38 11.98 2.17 -7.50 -0.49 0.05 12.21 1.07
Bud Site 1.14 3.54 -0.63 -1.49 -3.08 -12.60 -15.67 -11.11 0.78 5.41 -3.81 -6.21 -3.49 0.32 3.93
Cell Periphery 0.29 2.31 0.12 -0.17 -2.24 -9.28 -8.55 -4.35 6.35 5.57 -2.81 -1.99 0.23 6.08 4.66
Cytoplasm -4.29 -5.60 -1.31 2.24 2.95 1.51 -7.51 -7.76 -21.97 -0.54 -1.22 -12.83 -13.31 -20.80 -1.04
Cytoplasmic Foci -8.41 1.55 2.70 10.17 1.95 5.97 8.70 8.20 12.03 -5.16 2.64 8.43 7.73 14.79 -4.08
Eisosomes -1.74 -1.60 -2.18 -1.74 -2.03 -2.13 -6.46 -5.30 -4.32 1.97 -3.71 -7.04 -6.43 -4.63 1.15
Endoplasmic Reticulum 1.41 0.58 0.05 -1.64 -0.65 -1.30 -0.88 0.64 5.60 5.13 0.70 0.79 1.83 4.59 5.02
Endosome 2.24 4.70 5.06 6.47 2.42 0.98 4.58 4.26 17.53 -3.82 1.61 6.94 6.54 18.27 -3.05
Golgi 1.42 1.75 1.66 1.19 -0.84 -5.29 1.68 -1.58 3.81 -2.92 0.74 1.81 1.49 3.89 -2.98
Lipid Particles -1.42 -3.10 -1.57 -0.19 1.34 3.05 3.77 3.54 1.89 -0.69 1.94 2.96 2.78 1.89 -0.22
Mitochondria 0.45 1.38 1.42 2.38 2.11 -0.76 1.11 0.40 3.55 -3.09 -0.82 1.72 0.73 3.64 -3.11
Mitotic Spindle 1.78 2.11 0.04 -1.25 -1.48 -3.74 -3.54 -4.75 -2.87 -2.00 0.69 0.23 -1.62 -3.06 -2.38
None -3.45 -6.00 -2.41 -0.44 4.13 -1.02 -1.52 -2.73 -2.34 -2.14 -2.78 -4.85 -3.50 -2.39 -1.87
Nuclear Periphery 1.12 0.34 0.75 -3.87 4.06 2.16 -0.70 0.86 -2.80 5.08 1.26 0.69 1.01 -3.35 7.60
Nuclear Periphery Foci -0.39 -3.01 -0.53 0.27 3.32 -0.69 -6.84 -4.49 -5.07 2.70 1.86 0.09 1.90 -0.55 5.82
Nucleolus -2.00 -4.21 1.08 2.46 5.79 1.21 2.31 1.83 2.28 -1.88 0.12 2.09 1.47 2.60 -1.07
Nucleus -3.08 -21.59 -4.54 -2.99 13.28 5.12 -6.46 -3.08 -23.38 7.02 3.28 -18.40 -10.18 -23.39 11.45
Peroxisomes -4.13 2.66 -0.16 3.34 -1.00 -1.48 2.41 1.82 5.30 -1.16 -3.84 3.08 1.81 6.33 -1.48
Vacuole 7.35 10.62 0.94 -5.63 -8.24 -1.93 5.40 2.37 13.60 -11.82 1.95 11.93 7.08 11.68 -13.14
Vacuole Periphery 1.86 2.83 2.87 2.56 5.35 -2.57 3.45 2.76 7.94 -1.30 0.76 3.39 3.14 8.16 -1.34
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Integral membrane peptide transporter; mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
Localization
Cell Percentages vacuole (12%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Ptr2

Ptr2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ptr2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available