Standard name
Human Ortholog
Description Ubiquitin-ribosomal 60S subunit protein L40B fusion protein; cleaved to yield ubiquitin and ribosomal protein L40B; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40B has a paralog, RPL40A, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0.07 0 0.05 0 0.07 0.05
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.33 0.42 0.34 0.3 – 0.91 0.89 0.88 0.65 0.59 0.6 0.53 0.46 0.43 0.52 0.74 0.71 0.79 0.29 0.38 0.41 0.52 0.45 0.54
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0.08 0.09 0.17 0 0 0 0 0 0 0 0.05 0.06
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 – 0.09 0.11 0.09 0.45 0.41 0.49 0.56 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.18 0.11 0.05 0.21 – 0 0 0 0 0.12 0.06 0.05 0.05 0.06 0 0.07 0 0 0.47 0.4 0.31 0.24 0.21 0.15
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.55 0.53 0.62 0.52 – 0 0 0 0 0 0 0 0.53 0.59 0.44 0.25 0.33 0.3 0.07 0.08 0.08 0.08 0.09 0.09
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 0 0 – 0 0 0 0 0 0 0 0 1 0 0 1 1 0 2 0 0 0 0
Bud 1 0 0 0 – 1 0 0 3 1 2 2 1 0 1 0 0 0 33 15 4 2 19 11
Bud Neck 0 0 0 0 – 2 2 2 1 0 0 2 0 0 0 0 0 0 2 2 0 0 2 0
Bud Site 0 0 0 0 – 0 0 0 1 1 1 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 3 0 0 – 1 1 1 1 0 0 0 0 0 1 2 2 0 0 0 0 0 0 0
Cytoplasm 138 154 19 24 – 150 163 165 71 67 74 58 72 124 171 166 189 202 138 149 37 49 128 122
Endoplasmic Reticulum 0 1 0 0 – 0 0 0 0 2 0 1 0 1 0 7 12 8 1 1 0 1 1 0
Endosome 15 3 0 2 – 1 0 1 1 0 0 0 13 26 56 0 1 2 6 5 3 3 15 13
Golgi 1 1 0 0 – 0 0 0 0 0 0 0 4 6 0 3 9 3 2 0 0 0 0 0
Mitochondria 0 3 0 0 – 15 20 16 50 47 61 62 0 1 2 5 0 0 1 4 0 0 1 2
Nucleus 76 40 3 17 – 4 6 4 4 14 8 6 7 17 9 16 8 7 223 159 28 22 60 33
Nuclear Periphery 0 0 0 0 – 0 0 0 0 1 0 0 0 0 0 0 0 0 2 3 1 2 3 2
Nucleolus 5 5 1 0 – 0 0 0 0 0 1 0 3 1 0 0 0 0 14 5 3 2 9 4
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 1 0 0 0 – 1 1 4 0 1 0 0 0 0 0 0 0 0 14 8 3 1 8 8
Vac/Vac Membrane 231 192 35 42 – 2 5 6 3 1 1 2 82 169 143 57 87 76 32 32 7 7 24 20
Unique Cell Count 421 364 56 80 165 183 188 110 114 124 110 155 287 327 225 266 257 479 395 92 95 284 227
Labelled Cell Count 468 403 58 85 177 198 199 135 135 148 133 182 346 383 256 309 299 479 395 92 95 284 227


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 17.2 11.3 14.9 10.7 – 4.6 4.4 4.6 3.7 3.8 3.6 3.6 15.1 12.5 10.2 26.4 33.2 33.8 15.6 17.6 17.6
Std Deviation (1e-4) 16.6 2.7 11.6 10.4 – 3.0 1.6 2.1 2.4 1.3 0.9 0.8 11.0 7.1 8.4 16.7 19.7 19.6 10.7 12.1 13.2
Intensity Change (Log2) – – – -0.47 – -1.68 -1.77 -1.69 -2.01 -1.97 -2.06 -2.04 0.02 -0.26 -0.54 0.83 1.15 1.18 0.07 0.24 0.24

WT3RAP60RAP220RAP300RAP380RAP460RAP540RAP620RAP70002040WT3HU80HU120HU16002040WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302040WT1AF100AF140AF18002040
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.5 – 8.7 8.5 8.2 3.7 3.0 3.2 2.3 1.6 1.3 2.5 5.6 5.3 6.6
Endoplasmic Reticulum 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 – 0 0 0 0 0 0 0 0 0 3.4 0 0 0
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 2.6 – 0 0 0 0 1.4 0 0 0 0 0 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.2 – -10.6 -10.5 -10.4 -8.7 -9.2 -9.6 -8.9 -1.2 -0.5 -2.6 -5.3 -4.2 -4.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 96.2876 111.3482 105.6558 81.3936 83.5292 103.4307 97.0155 112.1033 110.931 110.5896 101.398 118.7954 100.9458 114.7001 110.6947 113.7613 111.0787 110.2371
Actin 0.0102 0.0006 0.0049 0.0728 0.004 0.0034 0.0098 0.0011 0.0049 0.0003 0.0019 0.005 0.005 0.0004 0.0009 0.0001 0.0013 0.0031
Bud 0.0027 0.0007 0.0053 0.0037 0.0027 0.0034 0.0044 0.0051 0.0041 0.0036 0.0028 0.0036 0.0019 0.0005 0.0019 0.001 0.0009 0.0021
Bud Neck 0.0014 0.0007 0.0012 0.0015 0.0031 0.0046 0.0017 0.0008 0.0021 0.0016 0.0017 0.0056 0.0014 0.0007 0.0014 0.0016 0.0012 0.0023
Bud Periphery 0.0044 0.0006 0.003 0.0022 0.0023 0.0032 0.0056 0.0044 0.0075 0.0029 0.0033 0.0059 0.0028 0.0003 0.0018 0.0006 0.0006 0.0017
Bud Site 0.0019 0.0006 0.0019 0.0015 0.0006 0.0008 0.0032 0.0014 0.0075 0.0005 0.0008 0.0005 0.001 0.0004 0.0019 0.0002 0.0006 0.0003
Cell Periphery 0.0765 0.0194 0.0358 0.0062 0.0051 0.0166 0.0488 0.014 0.0375 0.0067 0.0043 0.0068 0.0369 0.0157 0.0304 0.0126 0.0028 0.0088
Cytoplasm 0.4791 0.8459 0.6222 0.4751 0.4911 0.5053 0.552 0.8819 0.6616 0.6328 0.7702 0.792 0.6333 0.9076 0.7423 0.6117 0.8009 0.7492
Cytoplasmic Foci 0.0096 0.0014 0.0103 0.0058 0.0348 0.0066 0.0172 0.0016 0.0157 0.0022 0.0206 0.0067 0.0087 0.001 0.0115 0.0022 0.0053 0.004
Eisosomes 0.0007 0 0.0017 0.0001 0.0002 0.0001 0.0008 0 0.0003 0 0.001 0.0005 0.0003 0 0.0001 0 0.0001 0
Endoplasmic Reticulum 0.0726 0.0228 0.0363 0.0191 0.0098 0.1271 0.0475 0.0113 0.0257 0.0033 0.0066 0.0353 0.0753 0.0209 0.0274 0.0227 0.026 0.0892
Endosome 0.0125 0.0043 0.0094 0.0266 0.044 0.0275 0.0191 0.0027 0.0206 0.0091 0.0147 0.018 0.0101 0.0023 0.0108 0.0148 0.0234 0.0195
Golgi 0.0041 0.001 0.0028 0.0048 0.0039 0.017 0.0034 0.0003 0.0049 0.0003 0.0049 0.0063 0.003 0.0006 0.0016 0.0003 0.002 0.0024
Lipid Particles 0.0064 0.0016 0.0109 0.0013 0.0148 0.0024 0.0074 0.0008 0.0047 0.0005 0.0105 0.0025 0.0028 0.001 0.0046 0.0005 0.0058 0.0015
Mitochondria 0.0083 0.0012 0.0122 0.0028 0.0173 0.0144 0.0129 0.0004 0.0039 0.0003 0.0155 0.0025 0.0074 0.0003 0.0026 0.0003 0.0018 0.0031
None 0.0042 0.0003 0.0074 0.0016 0.0107 0.0034 0.0088 0.0004 0.0017 0.0002 0.0314 0.002 0.0032 0.0002 0.0039 0.0002 0.0042 0.0004
Nuclear Periphery 0.0307 0.0053 0.0185 0.0245 0.0162 0.0107 0.0225 0.0029 0.006 0.0038 0.0033 0.0112 0.0185 0.0037 0.008 0.0061 0.0063 0.0105
Nucleolus 0.0058 0.0004 0.0037 0.0007 0.0057 0.0029 0.008 0.0001 0.0013 0.0004 0.003 0.0081 0.0012 0.0002 0.0016 0.0003 0.0001 0.0011
Nucleus 0.0089 0.0157 0.0111 0.0152 0.0064 0.0076 0.0101 0.0021 0.0048 0.0034 0.0028 0.0076 0.0057 0.0017 0.0038 0.0031 0.0021 0.0044
Peroxisomes 0.0006 0 0.0007 0.0059 0.0025 0.0002 0.0008 0 0.0013 0.0001 0.0011 0.0002 0.0018 0 0.0005 0 0.0003 0.0001
Punctate Nuclear 0.0016 0.0001 0.0024 0.0004 0.0352 0.0003 0.0014 0 0.0008 0 0.001 0.002 0.0005 0 0.0013 0 0.0003 0.0001
Vacuole 0.214 0.0695 0.1637 0.2634 0.1966 0.1928 0.1833 0.0632 0.161 0.2734 0.0744 0.0609 0.1538 0.0393 0.1263 0.2713 0.0951 0.0753
Vacuole Periphery 0.0438 0.0076 0.0346 0.0647 0.093 0.0497 0.0314 0.0054 0.0223 0.0547 0.024 0.0168 0.0253 0.0032 0.0154 0.0502 0.019 0.021

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 2222.4903 2602.2999 3101.7345 2278.4795 2778.0491 2607.3802 2085.4894 2031.5547 2119.0942 1910.6992
Translational Efficiency 1.1523 0.9836 0.9071 1.0941 1.1557 1.0556 1.1594 1.3959 1.3206 1.4098

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1246 1108 2296 1177 1482 1758 1989 2099 2728 2866 4285 3276

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 1006.46 1673.98 3312.83 3432.95 1191.44 2032.55 3271.35 3811.39 1106.95 1893.93 3293.58 3675.42
Standard Deviation 594.41 976.80 745.23 1016.83 722.53 1176.12 774.58 886.82 673.40 1117.07 759.28 953.07
Intensity Change Log 2 — 0.733992 1.718774 1.770159 — 0.770585 1.457180 1.677611 — 0.753943 1.582878 1.720729

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.001033 0.000798 0.000166 0.000565 0.000876 0.000937 0.000220 0.000108 0.000948 0.000883 0.000191 0.000272
Bud Neck 0.011078 0.026274 0.013311 0.006024 0.007466 0.028724 0.012401 0.001407 0.009116 0.027777 0.012889 0.003066
Bud Site 0.008669 0.009271 0.002365 0.010848 0.011216 0.018063 0.002165 0.003089 0.010052 0.014664 0.002272 0.005876
Cell Periphery 0.004830 0.004731 0.000687 0.009766 0.003360 0.003484 0.000698 0.002252 0.004031 0.003966 0.000692 0.004951
Cytoplasm 0.079075 0.175228 0.243476 0.658273 0.350318 0.159792 0.218621 0.826455 0.226429 0.165759 0.231939 0.766031
Cytoplasmic Foci 0.007061 0.003809 0.002039 0.006797 0.006426 0.005284 0.002523 0.003782 0.006716 0.004714 0.002263 0.004865
Eisosomes 0.000036 0.000013 0.000003 0.000006 0.000011 0.000015 0.000003 0.000001 0.000022 0.000014 0.000003 0.000003
Endoplasmic Reticulum 0.009435 0.001829 0.000279 0.000329 0.003988 0.002796 0.000336 0.000106 0.006476 0.002422 0.000305 0.000186
Endosome 0.002386 0.001306 0.000324 0.004540 0.001218 0.002201 0.000272 0.000454 0.001751 0.001855 0.000300 0.001922
Golgi 0.015398 0.010258 0.000755 0.003318 0.010392 0.010288 0.000963 0.004440 0.012679 0.010277 0.000852 0.004037
Lipid Particles 0.003426 0.002210 0.000370 0.007277 0.001381 0.002194 0.000560 0.002816 0.002315 0.002200 0.000458 0.004418
Mitochondria 0.003426 0.002837 0.002052 0.000791 0.002557 0.006224 0.001880 0.000380 0.002954 0.004915 0.001972 0.000528
Mitotic Spindle 0.002607 0.003414 0.014181 0.017373 0.003214 0.013377 0.009457 0.003615 0.002937 0.009525 0.011988 0.008558
None 0.014515 0.015442 0.011349 0.005998 0.021299 0.014316 0.011127 0.004606 0.018200 0.014751 0.011246 0.005106
Nuclear Periphery 0.001466 0.000725 0.003209 0.000595 0.000658 0.001718 0.002010 0.000276 0.001027 0.001334 0.002652 0.000391
Nuclear Periphery Foci 0.003410 0.003284 0.001326 0.003684 0.004276 0.005038 0.001060 0.003272 0.003881 0.004360 0.001202 0.003420
Nucleolus 0.025231 0.019717 0.004018 0.000545 0.004320 0.016156 0.003087 0.000223 0.013871 0.017532 0.003586 0.000338
Nucleus 0.768701 0.664990 0.686401 0.163017 0.519163 0.635667 0.712068 0.097615 0.633138 0.647004 0.698315 0.121113
Peroxisomes 0.000694 0.000276 0.000048 0.002172 0.000164 0.000202 0.000044 0.000021 0.000406 0.000231 0.000046 0.000794
Vacuole 0.016924 0.028502 0.009263 0.091174 0.021880 0.039558 0.016089 0.040469 0.019616 0.035283 0.012432 0.058686
Vacuole Periphery 0.020600 0.025087 0.004379 0.006909 0.025817 0.033967 0.004417 0.004614 0.023434 0.030534 0.004396 0.005439

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.95 8.82 4.93 3.97 -0.77 -1.31 7.36 12.95 14.56 12.59 0.21 11.65 12.29 13.14 4.34
Bud Neck -9.80 -18.15 -4.50 5.38 11.65 -14.89 -19.46 2.70 16.44 20.76 -17.59 -26.85 -1.15 16.12 25.03
Bud Site -0.99 2.81 -1.83 -0.53 -5.34 -3.43 3.41 4.55 9.35 3.42 -3.72 4.41 3.18 7.47 -1.75
Cell Periphery 0.41 5.00 0.84 0.33 -4.40 0.32 7.02 3.15 2.76 -4.49 0.66 7.74 2.62 1.83 -6.17
Cytoplasm -9.71 -12.95 -42.83 -30.38 -36.06 20.26 22.05 -41.35 -77.26 -86.84 9.74 11.05 -58.17 -75.28 -85.75
Cytoplasmic Foci 2.62 1.55 -3.49 -7.58 -6.53 2.19 0.14 -0.14 -2.52 -0.29 3.32 1.41 -2.36 -6.90 -4.57
Eisosomes 10.01 13.28 12.69 5.93 -0.62 -4.96 2.65 12.99 18.86 14.42 6.52 13.15 16.72 18.65 10.33
Endoplasmic Reticulum 10.84 13.17 13.39 12.14 3.22 5.01 16.68 18.59 19.44 9.62 11.60 18.02 18.86 22.94 10.54
Endosome 3.05 7.96 0.64 -1.05 -2.45 -4.66 8.79 6.20 8.40 -0.28 -0.18 10.76 2.88 2.82 -2.44
Golgi 2.58 7.38 6.82 5.24 -4.53 0.79 7.82 5.27 5.54 -7.63 2.58 10.56 8.42 7.54 -8.77
Lipid Particles 2.08 4.71 -3.00 -6.10 -10.21 -1.80 1.73 -5.75 -3.90 -8.56 0.87 5.06 -5.07 -6.95 -13.47
Mitochondria 0.87 0.72 4.88 5.02 20.09 -5.59 -1.15 5.18 10.74 17.30 -4.10 -0.26 7.20 11.83 23.72
Mitotic Spindle -1.32 -10.73 -7.62 -6.69 -0.96 -5.49 -7.58 -3.34 2.73 4.63 -5.64 -12.87 -7.98 -2.30 3.28
None 0.10 1.65 4.87 5.66 11.01 4.02 6.07 9.85 8.01 13.57 3.10 5.66 10.82 9.84 18.20
Nuclear Periphery 3.82 -11.74 -2.65 -7.95 10.22 -8.90 -18.80 -0.75 8.32 18.30 -3.57 -20.37 -1.58 2.44 20.29
Nuclear Periphery Foci -0.21 2.36 -1.09 -0.87 -4.24 -0.53 4.56 -0.02 0.51 -4.65 -0.73 4.96 -0.76 0.00 -6.01
Nucleolus 0.62 0.78 11.71 8.98 14.51 -9.28 -10.88 5.85 12.54 14.73 -4.57 -6.15 13.06 15.34 21.16
Nucleus 7.47 6.99 42.84 32.67 47.32 -9.53 -16.87 37.22 51.61 78.38 -1.85 -8.17 56.14 60.83 92.46
Peroxisomes 2.77 3.38 -0.12 -0.99 -1.16 -2.11 -3.16 8.73 9.34 10.82 2.33 2.61 0.72 -0.17 -0.27
Vacuole -3.53 3.18 -18.08 -15.01 -19.57 -4.96 1.81 -9.40 -3.96 -11.08 -6.33 3.73 -19.50 -13.11 -22.26
Vacuole Periphery -0.49 6.87 6.55 6.53 -0.74 -1.16 8.65 8.06 10.13 -2.38 -1.37 11.03 10.36 12.02 -2.31
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Ubiquitin-ribosomal 60S subunit protein L40B fusion protein; cleaved to yield ubiquitin and ribosomal protein L40B; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; homologous to mammalian ribosomal protein L40, no bacterial homolog; RPL40B has a paralog, RPL40A, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (39%), nucleus (36%), mixed (24%)
Cell Cycle Regulation Yes
nucleus - S/G2 (0.00026)
Subcompartmental Group N/A

Rpl40b

Rpl40b


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Rpl40b-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
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Images are not yet available