Standard name
Human Ortholog
Description Protein required for cytochrome c oxidase assembly; located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.99 0.98 0.95 0.89 0.82 – 0.6 0.57 0.6 0.55 0.6 0.98 0.98 0.98 0.96 0.93 0.95 0.93 0.93 0.95 0.9 0.85 0.92
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.07 0.17 0.27 – 0.52 0.58 0.58 0.58 0.58 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0.05 – 0.08 0.06 0.08 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1
Bud 0 2 2 0 3 0 – 9 5 5 4 4 0 0 0 0 0 0 1 1 0 2 4 3
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 1 0 1 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 1 0 1 2 0 – 1 3 3 6 2 2 0 1 4 1 5 0 0 0 0 0 0
Cytoplasm 326 398 344 210 142 305 – 267 220 213 176 133 499 394 508 129 98 114 322 370 344 226 272 334
Endoplasmic Reticulum 1 2 1 2 2 2 – 1 2 1 3 3 5 2 6 4 2 3 0 3 1 0 3 3
Endosome 0 0 0 0 0 0 – 1 0 3 1 0 0 0 0 0 1 1 4 5 2 0 3 3
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 1 0 0 3 1 3 1 0 1 5 1
Mitochondria 4 1 5 16 27 102 – 232 225 205 186 129 0 0 1 0 1 5 3 1 2 0 1 1
Nucleus 0 0 0 0 5 4 – 5 5 5 11 5 13 5 5 4 1 0 5 4 2 5 7 1
Nuclear Periphery 0 0 0 1 0 0 – 1 4 1 0 1 0 0 0 0 0 0 1 1 0 2 0 1
Nucleolus 0 0 0 1 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
SpindlePole 0 0 0 0 0 0 – 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 1 1
Vac/Vac Membrane 3 3 4 4 4 18 – 37 23 29 16 7 7 4 6 4 3 4 1 3 1 7 11 5
Unique Cell Count 333 402 351 221 159 373 448 385 353 320 221 511 400 519 135 105 120 347 400 364 252 322 363
Labelled Cell Count 334 407 356 235 185 431 554 488 467 403 285 526 406 527 145 110 133 347 400 364 252 322 363


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.5 12.6 6.8 7.5 4.7 4.8 – 4.3 3.9 3.9 4.0 4.1 12.2 9.9 7.8 11.2 11.0 10.1 12.6 11.1 10.1
Std Deviation (1e-4) 1.6 2.0 1.3 1.8 1.6 1.1 – 1.0 1.0 0.8 1.1 0.7 2.3 1.6 1.5 2.6 2.4 2.4 2.3 2.2 1.5
Intensity Change (Log2) – – – 0.14 -0.54 -0.51 – -0.67 -0.82 -0.79 -0.76 -0.74 0.84 0.54 0.2 0.72 0.68 0.57 0.88 0.7 0.56

WT3RAP60RAP140RAP220RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -2.0 -4.3 -7.2 – -12.7 -13.1 -12.3 -13.3 -11.8 -0.3 0.5 -0.1 -1.5 -2.4 -1.7
Endoplasmic Reticulum 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 3.6 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 – 0 0 0 3.5 0 3.0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 0 2.9 – 4.5 3.5 4.4 2.9 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 6.8873 8.9029 8.6504 7.5174 7.5111 8.2233 5.4718 7.2407 6.548 5.6343 6.2623 6.248 8.422 9.8896 9.5578 8.707 9.2043 9.1506
Actin 0.0065 0.0008 0.0071 0.0012 0.0312 0.0006 0.0169 0.0024 0.0218 0.0036 0.0402 0.0102 0.0008 0.0004 0.0003 0.0005 0.0008 0.0006
Bud 0.0078 0.0015 0.0063 0.0071 0.0001 0.0042 0.0011 0.0002 0.0025 0.0014 0.0037 0.0003 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001
Bud Neck 0.0049 0.0006 0.0015 0.0018 0.0014 0.0053 0.0057 0.0002 0.0029 0.0038 0.0026 0.0012 0.0009 0.0006 0.0016 0.001 0.0008 0.0026
Bud Periphery 0.001 0.0004 0.0017 0.0042 0.0002 0.0011 0.0015 0 0.003 0.002 0.0046 0.0002 0.0001 0 0 0 0 0
Bud Site 0.002 0.0047 0.0025 0.0012 0.0003 0.0034 0.0035 0.0005 0.0027 0.0117 0.0161 0.0002 0.0005 0.0007 0.0029 0.0002 0.0001 0.0001
Cell Periphery 0.0001 0 0.0001 0.0003 0.0001 0 0.0003 0 0.0002 0.0003 0.0004 0 0 0 0 0 0 0
Cytoplasm 0.8609 0.9366 0.8894 0.8509 0.83 0.8582 0.8148 0.9624 0.8471 0.7822 0.7216 0.8654 0.8766 0.9263 0.8997 0.851 0.845 0.8844
Cytoplasmic Foci 0.0072 0.0017 0.0028 0.011 0.002 0.0039 0.0118 0.0029 0.0108 0.0216 0.022 0.0061 0.007 0.0025 0.0022 0.0029 0.0033 0.003
Eisosomes 0.0001 0 0 0 0.0013 0 0.0001 0 0.0001 0.0001 0.0002 0 0 0 0 0 0.0001 0
Endoplasmic Reticulum 0.0061 0.0016 0.0018 0.0038 0.0029 0.0023 0.0073 0.0013 0.0032 0.0047 0.007 0.0035 0.0041 0.0019 0.0016 0.0028 0.0026 0.0033
Endosome 0.009 0.0007 0.0011 0.0011 0.0021 0.0016 0.0288 0.001 0.0166 0.0457 0.0536 0.0113 0.0049 0.0018 0.0011 0.0018 0.0024 0.0017
Golgi 0.0008 0.0001 0.0002 0.0001 0.0019 0.0001 0.0066 0.0002 0.0068 0.008 0.0197 0.0044 0.0007 0.0001 0.0001 0.0001 0.0002 0.0001
Lipid Particles 0.0004 0 0 0.0001 0.0012 0 0.0064 0 0.0023 0.0079 0.0081 0.0009 0.0005 0 0 0 0.0019 0
Mitochondria 0.002 0.0001 0.0008 0.0003 0.0005 0.0003 0.0084 0.0002 0.0029 0.0034 0.0099 0.0036 0.0005 0.0002 0.0002 0.0003 0.0359 0.0002
None 0.0108 0.0029 0.0039 0.0276 0.006 0.0035 0.0168 0.0041 0.0025 0.0098 0.007 0.0025 0.0142 0.0087 0.0033 0.0064 0.0069 0.0036
Nuclear Periphery 0.0113 0.0026 0.0063 0.0061 0.0089 0.0048 0.0109 0.0019 0.0104 0.0075 0.018 0.0067 0.0053 0.0032 0.0031 0.0055 0.0055 0.0051
Nucleolus 0.0005 0.0001 0.0003 0.0005 0.0002 0.0001 0.0004 0 0.0002 0.0027 0.0011 0.0002 0.0004 0.0002 0.0001 0.0002 0.0001 0.0001
Nucleus 0.0602 0.0433 0.0695 0.0692 0.1053 0.106 0.0419 0.0209 0.0539 0.0524 0.0385 0.0734 0.0754 0.0482 0.081 0.1226 0.0828 0.091
Peroxisomes 0.0005 0.0001 0.0002 0.0002 0.0008 0.0001 0.0057 0.0004 0.0023 0.0019 0.0049 0.0004 0.0009 0.0001 0.0001 0.0001 0.0047 0.0002
Punctate Nuclear 0.0044 0.0016 0.0033 0.0095 0.0026 0.0036 0.005 0.0008 0.0035 0.0205 0.0121 0.0081 0.0056 0.0041 0.0022 0.0034 0.0059 0.0034
Vacuole 0.0028 0.0006 0.0008 0.0034 0.0007 0.0007 0.0038 0.0004 0.0035 0.0075 0.0051 0.001 0.0013 0.0008 0.0004 0.001 0.0008 0.0006
Vacuole Periphery 0.0008 0.0001 0.0003 0.0003 0.0003 0.0001 0.0023 0.0001 0.0007 0.0011 0.004 0.0004 0.0002 0.0001 0.0001 0.0002 0.0002 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 33.4365 36.5325 32.0375 27.8702 33.7181 37.1311 26.8639 32.8631 39.6323 26.8623
Translational Efficiency 1.1325 1.1303 1.3004 1.6162 1.2991 1.0625 1.2362 1.5451 1.1915 1.3475

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
330 1459 711 1189 1202 1921 19 757 1532 3380 730 1946

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 713.07 1030.44 1085.52 1093.51 965.50 953.17 485.27 1093.52 911.13 986.52 1069.90 1093.51
Standard Deviation 101.20 178.07 190.81 180.39 151.30 158.37 98.48 163.21 175.89 171.48 211.77 173.91
Intensity Change Log 2 — 0.531145 0.606271 0.616851 — -0.018543 -0.992489 0.179631 — 0.240896 -0.095742 0.381740

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000167 0.000531 0.000296 0.004213 0.000226 0.000421 0.003218 0.002215 0.000213 0.000469 0.000372 0.003436
Bud Neck 0.006518 0.000983 0.002076 0.011682 0.000871 0.001316 0.015065 0.004662 0.002088 0.001172 0.002414 0.008951
Bud Site 0.013990 0.004088 0.007423 0.036884 0.003027 0.004402 0.050537 0.039094 0.005389 0.004266 0.008545 0.037744
Cell Periphery 0.000269 0.000061 0.000336 0.000152 0.000131 0.000095 0.017626 0.000206 0.000161 0.000081 0.000786 0.000173
Cytoplasm 0.667222 0.795933 0.443847 0.510819 0.770218 0.744434 0.023877 0.484093 0.748032 0.766664 0.432916 0.500422
Cytoplasmic Foci 0.172385 0.028165 0.018635 0.009882 0.045642 0.033356 0.006076 0.027689 0.072943 0.031115 0.018308 0.016809
Eisosomes 0.000064 0.000011 0.000076 0.000021 0.000017 0.000017 0.000738 0.000032 0.000027 0.000014 0.000093 0.000025
Endoplasmic Reticulum 0.002123 0.000693 0.002725 0.002280 0.002204 0.001339 0.018194 0.002365 0.002187 0.001060 0.003127 0.002313
Endosome 0.005791 0.001931 0.003301 0.008620 0.002264 0.002668 0.000593 0.020686 0.003024 0.002350 0.003230 0.013314
Golgi 0.002274 0.000688 0.000131 0.003515 0.000338 0.001545 0.000297 0.016948 0.000755 0.001175 0.000136 0.008740
Lipid Particles 0.003432 0.000455 0.001855 0.001027 0.000948 0.001089 0.012687 0.001526 0.001483 0.000816 0.002137 0.001221
Mitochondria 0.002427 0.001680 0.000323 0.005188 0.000160 0.000845 0.002371 0.032494 0.000649 0.001206 0.000376 0.015810
Mitotic Spindle 0.000341 0.001590 0.001510 0.088330 0.000528 0.001418 0.000170 0.082451 0.000488 0.001492 0.001475 0.086043
None 0.009056 0.007696 0.015379 0.009883 0.004057 0.010743 0.225213 0.009682 0.005134 0.009428 0.020841 0.009805
Nuclear Periphery 0.000248 0.000191 0.000886 0.001581 0.000287 0.000267 0.000354 0.000970 0.000279 0.000234 0.000872 0.001344
Nuclear Periphery Foci 0.000741 0.003049 0.003824 0.004415 0.006282 0.003309 0.011217 0.005184 0.005088 0.003197 0.004017 0.004715
Nucleolus 0.000872 0.000349 0.001097 0.000373 0.000196 0.000507 0.023792 0.000208 0.000342 0.000439 0.001688 0.000309
Nucleus 0.080859 0.120082 0.401125 0.196656 0.126477 0.161459 0.575267 0.114865 0.116651 0.143598 0.405658 0.164839
Peroxisomes 0.001474 0.000391 0.000377 0.000621 0.000212 0.000900 0.000789 0.012756 0.000484 0.000680 0.000388 0.005342
Vacuole 0.028271 0.031187 0.094562 0.097202 0.035709 0.029508 0.011758 0.129374 0.034107 0.030233 0.092406 0.109717
Vacuole Periphery 0.001476 0.000247 0.000215 0.006656 0.000205 0.000362 0.000162 0.012500 0.000478 0.000312 0.000214 0.008929

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.36 -7.78 -1.98 -1.18 -1.37 -1.35 -1.58 -3.24 -1.65 1.33 -1.79 -4.55 -2.55 -1.64 -1.44
Bud Neck 4.45 2.92 0.38 -7.60 -4.60 -1.41 -2.14 -9.24 -5.97 1.80 2.86 -2.72 -5.81 -8.77 -3.51
Bud Site 3.59 2.28 0.12 -5.40 -2.92 -1.52 -1.91 -5.88 -4.82 1.51 1.47 -1.36 -5.87 -7.05 -2.64
Cell Periphery 7.34 -0.67 4.72 -8.86 8.94 3.24 -2.04 -0.26 -2.88 2.04 7.78 -2.39 2.45 -6.92 2.51
Cytoplasm -8.16 17.13 17.65 42.49 -1.22 3.65 52.12 32.94 31.26 -22.84 -1.95 33.04 43.70 51.82 -1.86
Cytoplasmic Foci 15.60 17.37 18.26 12.69 6.06 4.35 11.86 13.83 11.45 -2.32 13.07 18.90 21.52 17.91 4.44
Eisosomes 8.85 -0.97 6.26 -7.88 9.77 0.05 -1.73 -10.35 -9.80 1.69 6.63 -4.93 -2.10 -12.00 4.66
Endoplasmic Reticulum 2.91 -3.10 0.58 -7.25 6.78 4.63 -2.99 3.89 -0.72 3.14 6.49 -5.77 2.80 -5.17 8.00
Endosome 6.50 3.93 5.63 -0.51 2.95 -1.23 6.01 -1.71 -1.06 -3.98 2.44 -1.24 0.89 -0.76 1.68
Golgi 3.18 4.43 3.10 -0.01 -1.89 -2.53 0.19 -2.08 -0.60 -2.08 -1.26 4.95 -1.18 -0.15 -2.85
Lipid Particles 7.71 3.64 4.66 -14.63 2.28 -0.76 -0.95 -4.41 -2.43 0.89 4.23 -2.11 -1.28 -6.40 1.69
Mitochondria 1.00 5.60 1.70 -0.04 -2.76 -2.85 -2.65 -2.51 -2.07 -0.98 -1.06 2.42 -2.79 -1.83 -3.15
Mitotic Spindle -1.96 -3.06 -9.21 -8.76 -8.41 -1.56 1.56 -7.30 -7.01 -7.40 -2.28 -2.80 -11.70 -11.22 -10.57
None 0.95 -0.73 0.49 -1.21 1.78 -5.76 -2.50 -4.27 2.41 2.46 -4.58 -3.81 -3.98 1.48 2.90
Nuclear Periphery 0.49 -14.78 -19.43 -22.48 -6.95 0.47 -0.56 -15.76 -16.48 -10.82 0.92 -16.19 -24.61 -27.00 -6.43
Nuclear Periphery Foci -6.99 -7.56 -6.52 2.21 4.44 4.93 -0.77 5.21 0.45 1.29 3.76 -0.18 5.41 2.26 4.20
Nucleolus 1.69 0.17 1.75 -0.16 4.08 -3.73 -1.59 -2.49 2.87 1.58 -1.11 -2.63 0.24 1.66 2.71
Nucleus -6.91 -28.62 -21.21 -18.95 12.72 -6.92 -4.81 -6.71 -1.92 4.26 -7.30 -28.07 -19.44 -15.16 16.75
Peroxisomes 6.15 6.47 7.78 2.17 1.35 -2.50 -1.33 -1.73 -0.83 -1.07 -1.37 1.84 -0.98 -0.24 -1.39
Vacuole -3.02 -14.37 -25.91 -25.75 -9.76 2.15 3.99 -26.94 -27.77 -25.52 0.02 -14.24 -36.96 -37.75 -14.55
Vacuole Periphery 6.74 7.01 0.76 -1.73 -1.79 -2.73 0.63 -2.22 -1.97 -2.28 3.14 5.11 -2.06 -2.52 -2.78
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Protein required for cytochrome c oxidase assembly; located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase; contains twin cysteine-x9-cysteine motifs
Localization
Cell Percentages cytoplasm (99%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Cox19

Cox19


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cox19-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available