Standard name
Human Ortholog
Description Transmembrane nucleoporin; involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0.06 0 0.05 0 0 0 0 0 0
Cytoplasm 0.1 0 0 0.05 0.05 0.07 0.05 0 0 0 0 0 0 0.11 0.16 0.09 0.17 0.12 0 0 0 0 0 0
Endoplasmic Reticulum 0.18 0.08 0 0 0 0.26 0.05 0.06 0.07 0.05 0.09 0.09 0.2 0.17 0.27 0.06 0 0 0.27 0.14 0.09 0.05 0 0.11
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0.09 0 0 0 0 0 0 0 0.13 0.09
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.33 0.27 0.25 0 0 0 0 0 0.08
Mitochondria 0.24 0.08 0.58 0.5 0.53 0.58 0.61 0.62 0.7 0.58 0.68 0.75 0 0 0 0.11 0 0.07 0 0 0.06 0.07 0.11 0.16
Nucleus 0.09 0 0 0.07 0 0.05 0.07 0 0 0.05 0.08 0.06 0.06 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0.52 0.53 0.41 0.46 0.37 0.28 0.28 0.22 0.34 0.31 0.28 0.2 0.41 0.36 0.36 0.12 0.07 0.16 0.57 0.66 0.72 0.72 0.52 0.4
Nucleolus 0 0 0 0 0 0 0 0.07 0.05 0 0.05 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.12 0.61 0.29 0.25 0.29 0.13 0.24 0.2 0.15 0.23 0.16 0.09 0.43 0.43 0.31 0.3 0.44 0.39 0 0.08 0 0 0.07 0.07
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 0 0 1 6 1 2 2 6 1 6 1 2 3 5 4 1 4 0 4 0 2 2
Bud 1 1 3 1 1 4 9 6 7 13 9 7 1 0 0 0 1 0 2 3 1 1 2 3
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
Bud Site 0 0 0 1 1 4 5 2 1 9 6 9 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 4 0 2 3 3 1 2 3 2 4 0 7 6 4 2 3 0 0 0 0 0 0
Cytoplasm 11 3 7 11 17 27 27 22 13 20 20 23 3 17 23 6 12 7 0 1 1 1 1 3
Endoplasmic Reticulum 20 11 5 8 14 100 25 39 26 30 45 53 16 26 40 4 1 2 36 23 20 3 7 17
Endosome 1 3 6 6 14 0 13 12 4 14 2 3 2 7 13 0 2 0 2 3 5 2 22 15
Golgi 0 1 0 0 0 0 1 2 0 0 1 4 0 3 11 21 19 14 0 2 1 1 6 13
Mitochondria 27 12 125 105 166 223 312 380 282 334 355 455 2 1 2 7 3 4 2 3 15 5 19 26
Nucleus 10 4 8 15 8 18 35 25 18 30 40 35 5 4 2 0 1 0 0 3 1 0 0 1
Nuclear Periphery 58 75 89 96 117 109 144 136 134 179 143 119 34 54 52 8 5 9 77 107 177 54 88 65
Nucleolus 3 0 7 3 7 5 18 45 19 23 25 31 0 1 1 1 2 1 0 0 0 0 0 0
Peroxisomes 0 0 1 0 0 0 0 0 0 3 1 0 0 0 0 0 0 0 0 0 1 0 0 0
SpindlePole 0 0 0 0 2 2 2 1 0 3 2 2 1 1 1 0 0 0 0 0 3 1 4 2
Vac/Vac Membrane 13 86 62 53 91 52 121 123 62 133 81 54 35 65 45 19 31 22 2 13 4 3 12 11
Unique Cell Count 111 142 216 208 315 386 511 611 400 574 520 606 82 150 146 64 71 57 135 162 245 76 172 167
Labelled Cell Count 145 197 317 299 441 553 716 796 570 800 733 805 100 188 199 75 83 63 135 162 245 76 172 167


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.9 9.4 5.7 5.8 5.7 5.9 5.8 6.2 5.8 6.2 5.9 6.2 7.7 10.2 11.0 16.5 15.8 15.9 7.0 8.1 10.3
Std Deviation (1e-4) 2.4 2.6 1.5 1.9 1.5 1.5 1.8 1.8 1.8 1.9 1.9 2.3 1.9 3.1 3.0 4.7 5.1 3.9 1.6 2.8 7.0
Intensity Change (Log2) – – – 0.04 0.01 0.05 0.03 0.12 0.04 0.13 0.06 0.14 0.45 0.84 0.95 1.54 1.47 1.49 0.3 0.51 0.85


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.0 1.2 1.9 1.2 0.2 0 0.2 0.4 0.4 0 3.1 4.2 0 0 0
Endoplasmic Reticulum 0.9 1.3 7.3 1.6 2.3 2.3 1.8 3.1 3.2 5.2 5.1 7.1 0 0 0
Endosome 0.1 1.0 0 -0.2 0 0 -0.3 0 0 0 1.0 2.6 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.5 -1.2 0 0.8 1.1 3.2 0.1 2.7 4.8 -8.6 -11.3 -11.1 -6.6 -7.9 -6.8
Nucleus 1.6 -0.8 0.6 1.6 0.3 0.5 0.9 2.0 1.2 0 0 0 0 0 0
Nuclear Periphery 1.0 -0.9 -3.2 -3.4 -5.4 -1.9 -2.7 -3.6 -6.3 0 -1.0 -1.1 -4.2 -5.3 -3.6
Nucleolus 0 -0.7 0 0.2 2.1 0.9 0.5 0.9 1.1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -0.7 0 -4.6 -1.4 -2.6 -3.9 -1.6 -4.1 -7.2 2.3 2.9 0.4 0.2 2.3 1.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 7.5189 6.1778 6.1979 5.5929 6.1834 6.3389 9.1808 7.8834 8.3359 8.0758 7.0829 7.9877 7.752 6.1504 6.3599 4.7006 4.815 5.5758
Actin 0.0018 0.0004 0.0003 0.0006 0.0002 0.0004 0.0057 0.0174 0.0005 0.0011 0.0003 0.0002 0.001 0.0005 0.0009 0.001 0.0071 0.0003
Bud 0 0 0 0 0 0.0004 0 0.0003 0 0.0001 0 0 0 0 0 0 0 0
Bud Neck 0.0001 0.0002 0.0002 0.0001 0.0001 0.0005 0.0001 0.0003 0 0.0015 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0002 0.0001
Bud Periphery 0 0 0 0 0 0.0002 0.0001 0.0003 0.0001 0.0003 0.0001 0 0 0.0001 0.0001 0.0001 0.0002 0
Bud Site 0.0001 0.0005 0.0001 0 0 0.0001 0.0001 0.0055 0 0.0025 0 0 0.0001 0 0 0 0 0
Cell Periphery 0.0001 0.0001 0.0001 0 0 0.0001 0.0001 0.0009 0.0001 0.0006 0.0002 0 0.0001 0.0002 0.0002 0.0001 0.0005 0.0001
Cytoplasm 0.0017 0.0151 0.0069 0.001 0.0017 0.0045 0.0015 0.0008 0.0005 0.0046 0.0004 0.0017 0.0037 0.001 0.0007 0.0005 0.0006 0.0006
Cytoplasmic Foci 0.0015 0.001 0.0003 0.0003 0.0002 0.0007 0.0019 0.0007 0.0002 0.0006 0.0002 0.0007 0.0024 0.0001 0.0001 0.0004 0.0006 0.0002
Eisosomes 0 0 0 0 0 0 0 0.0001 0 0.0001 0 0 0 0 0 0 0.0001 0
Endoplasmic Reticulum 0.1223 0.2087 0.1872 0.1051 0.1789 0.1579 0.2033 0.2173 0.2857 0.2455 0.2769 0.2142 0.1779 0.3243 0.2961 0.1325 0.1999 0.2547
Endosome 0.0064 0.0124 0.008 0.0049 0.0082 0.0053 0.0064 0.003 0.0039 0.0105 0.0068 0.0034 0.006 0.0036 0.0038 0.0073 0.0175 0.0035
Golgi 0.0009 0.0004 0.0004 0.0004 0.0003 0.0003 0.0009 0.0028 0.0004 0.0008 0.0012 0.0002 0.0008 0.0002 0.0005 0.0012 0.0052 0.0005
Lipid Particles 0.0023 0.0038 0.0015 0.0008 0.0026 0.0015 0.004 0.0163 0.0031 0.0034 0.0075 0.0013 0.0037 0.0016 0.0022 0.0091 0.0144 0.0027
Mitochondria 0.0008 0.0003 0.0007 0.0009 0.0006 0.001 0.0009 0.0022 0.001 0.0013 0.0007 0.0004 0.0005 0.0008 0.0006 0.0013 0.0028 0.0007
None 0.0005 0.0005 0.0003 0.0002 0.0003 0.0004 0.0005 0.0001 0.0013 0.0043 0.0002 0.0042 0.0007 0.0001 0.0002 0.0003 0.0005 0.0001
Nuclear Periphery 0.8089 0.6803 0.7148 0.8436 0.7611 0.7784 0.7333 0.69 0.6622 0.6665 0.6778 0.7456 0.7643 0.6271 0.6571 0.8026 0.7203 0.709
Nucleolus 0.0001 0.0007 0.0005 0.0001 0.0002 0.0009 0.0002 0.0001 0.0001 0.0056 0.0001 0.0004 0.0001 0.0002 0 0.0001 0.0002 0.0012
Nucleus 0.025 0.0497 0.0466 0.0179 0.0176 0.029 0.0075 0.0036 0.0043 0.017 0.0031 0.0059 0.0103 0.0128 0.0074 0.0061 0.0045 0.007
Peroxisomes 0.0008 0 0 0 0 0 0.0008 0 0.0001 0.0001 0 0 0.0021 0 0 0.0001 0.0001 0
Punctate Nuclear 0.0038 0.0035 0.003 0.004 0.0014 0.0013 0.0063 0.0079 0.0013 0.0039 0.0013 0.0037 0.0011 0.0007 0.0004 0.0013 0.0022 0.002
Vacuole 0.0035 0.0095 0.0058 0.0019 0.0041 0.0035 0.003 0.0035 0.0033 0.0061 0.003 0.0019 0.0033 0.005 0.0034 0.0035 0.0042 0.0018
Vacuole Periphery 0.0196 0.013 0.0232 0.0181 0.0224 0.0136 0.0233 0.0271 0.032 0.0237 0.0201 0.0158 0.0218 0.0213 0.0259 0.0323 0.0188 0.0154

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 53.8566 36.402 25.2691 48.8575 28.1013 60.3911 44.2266 54.4912 50.4044 61.0369
Translational Efficiency 1.0842 1.3263 1.8845 0.8312 1.8723 1.544 1.4221 1.1263 1.6745 1.2148

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1347 1236 2739 1437 1791 907 2483 1787 3138 2143 5222 3224

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 922.85 905.70 1644.53 1780.17 897.55 860.63 1449.23 1378.59 908.41 886.62 1551.67 1557.58
Standard Deviation 158.97 187.52 341.51 456.51 202.00 152.33 291.67 441.57 185.18 174.92 333.37 490.72
Intensity Change Log 2 — -0.027063 0.833507 0.947847 — -0.060599 0.691222 0.619129 — -0.043501 0.765106 0.795103

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000117 0.000325 0.000218 0.001553 0.000354 0.000208 0.000159 0.001134 0.000253 0.000275 0.000190 0.001321
Bud Neck 0.000121 0.000815 0.001474 0.006683 0.000595 0.000556 0.000568 0.002535 0.000392 0.000705 0.001043 0.004384
Bud Site 0.000161 0.000514 0.001306 0.017322 0.001691 0.000799 0.000763 0.009279 0.001034 0.000635 0.001048 0.012864
Cell Periphery 0.000134 0.000145 0.000471 0.005873 0.000365 0.000100 0.000335 0.002402 0.000266 0.000126 0.000406 0.003949
Cytoplasm 0.004037 0.014061 0.007290 0.009649 0.017227 0.014102 0.004083 0.017617 0.011565 0.014078 0.005765 0.014066
Cytoplasmic Foci 0.000690 0.007329 0.000254 0.003509 0.006212 0.007382 0.000183 0.003827 0.003841 0.007352 0.000220 0.003686
Eisosomes 0.000004 0.000012 0.000005 0.000097 0.000014 0.000013 0.000005 0.000192 0.000010 0.000012 0.000005 0.000149
Endoplasmic Reticulum 0.101565* 0.077018 0.658915* 0.637509* 0.140867* 0.050367 0.583515* 0.492503* 0.123996* 0.065738 0.623063* 0.557135*
Endosome 0.010202 0.016543 0.028220 0.047286 0.024393 0.011723 0.029757 0.042783 0.018301 0.014503 0.028951 0.044790
Golgi 0.000461 0.002467 0.000446 0.010165 0.003743 0.001991 0.000520 0.006972 0.002334 0.002266 0.000481 0.008395
Lipid Particles 0.019108 0.034019 0.007435 0.075557 0.033939 0.053510 0.006990 0.028495 0.027573 0.042269 0.007223 0.049471
Mitochondria 0.004445 0.007101 0.000738 0.000789 0.006497 0.011249 0.000581 0.001850 0.005616 0.008856 0.000664 0.001377
Mitotic Spindle 0.001227 0.004590 0.001284 0.015551 0.001827 0.008183 0.001938 0.006972 0.001570 0.006111 0.001595 0.010796
None 0.001571 0.005357 0.002070 0.001314 0.010835 0.003344 0.001693 0.006846 0.006858 0.004505 0.001891 0.004380
Nuclear Periphery 0.315847* 0.255359* 0.099207 0.018129 0.176837* 0.278848* 0.127587* 0.081054 0.236508* 0.265300* 0.112702* 0.053007
Nuclear Periphery Foci 0.531168* 0.546560* 0.186028 0.130155 0.550733* 0.527622* 0.237980* 0.274050* 0.542335* 0.538545* 0.210731* 0.209913*
Nucleolus 0.000815 0.004502 0.000018 0.000047 0.004357 0.004566 0.000020 0.000739 0.002837 0.004529 0.000019 0.000431
Nucleus 0.002702 0.012460 0.001153 0.001146 0.009886 0.011681 0.000547 0.005064 0.006802 0.012131 0.000865 0.003318
Peroxisomes 0.000159 0.000885 0.000008 0.000052 0.000558 0.001464 0.000007 0.000091 0.000387 0.001130 0.000007 0.000074
Vacuole 0.003288 0.006351 0.003142 0.015397 0.005517 0.007138 0.002430 0.013466 0.004560 0.006684 0.002804 0.014326
Vacuole Periphery 0.002178 0.003586 0.000316 0.002217 0.003553 0.005155 0.000339 0.002129 0.002963 0.004250 0.000327 0.002168

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.91 -2.30 -6.16 -5.36 -5.58 2.18 1.10 -4.11 -4.76 -4.44 -0.32 -0.00 -7.07 -6.99 -6.99
Bud Neck -2.51 -6.72 -10.38 -8.82 -7.82 0.06 -0.58 -7.83 -6.82 -7.34 -1.81 -5.96 -12.66 -10.64 -9.84
Bud Site -3.35 -4.01 -8.63 -8.47 -7.90 1.55 1.13 -5.82 -6.28 -6.16 1.40 -1.03 -10.32 -10.61 -9.97
Cell Periphery -0.46 -8.37 -6.68 -6.66 -6.23 6.46 0.09 -7.02 -7.95 -6.80 5.50 -3.25 -8.88 -9.22 -8.42
Cytoplasm -5.12 -3.92 -4.87 1.43 -2.37 0.91 7.66 -0.51 -1.36 -8.57 -1.69 5.07 -2.45 -0.37 -8.07
Cytoplasmic Foci -5.91 2.95 -6.91 3.14 -8.20 -1.00 8.38 2.81 2.95 -7.96 -3.90 8.62 0.25 4.24 -11.21
Eisosomes -5.35 -1.40 -6.37 -5.82 -6.28 0.34 4.37 -1.37 -1.38 -1.44 -2.18 3.74 -1.97 -1.93 -2.03
Endoplasmic Reticulum 3.72 -66.63* -47.32* -51.53* 2.82 13.85 -48.84* -32.45 -43.68* 8.00 12.23 -80.30 -54.34 -64.98* 8.67
Endosome -4.18 -16.82 -20.41 -14.45 -10.24 7.05 -3.54 -9.26 -15.42 -7.14 3.04 -10.87 -19.17 -20.51 -12.16
Golgi -4.38 0.07 -7.76 -5.74 -7.79 2.11 5.05 -3.27 -5.29 -8.39 0.12 5.07 -7.69 -7.80 -11.32
Lipid Particles -4.67 6.38 -12.15 -8.14 -15.43 -4.25 12.38 1.72 5.35 -9.97 -5.38 13.79 -8.31 -2.34 -18.07
Mitochondria -2.52 4.40 4.30 8.88 -0.36 -2.89 8.14 5.79 6.14 -3.98 -3.56 9.00 7.25 9.65 -3.71
Mitotic Spindle -3.97 -0.33 -7.30 -5.58 -7.24 -3.50 -0.43 -4.81 0.21 -4.19 -5.05 -0.42 -8.72 -4.05 -8.38
None -4.19 -1.43 0.58 4.26 1.65 4.97 6.62 2.22 -2.39 -3.98 2.18 6.18 2.39 0.39 -3.36
Nuclear Periphery 6.57 29.70* 43.92* 35.10* 23.55 -10.95 8.09 16.27 22.94* 9.29 -4.30 25.87 39.63 38.71* 18.77
Nuclear Periphery Foci -1.27 38.44* 41.38* 41.46* 7.36 1.93 34.15* 26.60* 20.58* -3.82 0.56 51.61 45.37 40.82* 0.12
Nucleolus -4.75 3.41 3.20 5.95 -1.62 -0.17 6.52 5.36 4.10 -4.68 -2.35 7.13 5.99 6.97 -4.85
Nucleus -5.07 1.66 1.25 5.81 -0.53 -0.97 7.15 3.01 3.54 -5.29 -3.67 7.07 3.33 6.31 -4.90
Peroxisomes -3.32 6.76 4.53 3.81 -6.15 -1.73 6.21 5.20 2.67 -4.28 -2.85 7.29 5.94 4.16 -5.84
Vacuole -3.49 -0.62 -10.55 -7.65 -10.61 -1.23 4.91 -6.70 -4.34 -9.51 -2.80 3.33 -11.79 -8.36 -13.99
Vacuole Periphery -3.07 7.40 -0.15 2.55 -5.34 -1.45 8.64 3.15 2.80 -7.55 -2.35 11.05 2.42 3.83 -8.96
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Transmembrane nucleoporin; involved in nuclear pore complex (NPC) distribution, assembly or stabilization; highly conserved across species, orthologous to human TMEM33 and paralogous to Per33p; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages nuclear periphery (65%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Pom33

Pom33


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Pom33-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available