ORF
Human Ortholog
Description Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0.05 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.97 0.97 0.96 0.97 0.96 0.9 0.87 0.9 0.72 0.73 0.68 0.75 0.98 0.98 1.0 0.9 0.91 0.9 0.89 0.94 0.89 0.74 0.79 0.82
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.09 0.05 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0.06 0 0.16 0.22 0.13 0.39 0.37 0.48 0.29 0 0 0 0 0 0 0 0 0 0.08 0.06 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0.07 0.05 0.08 0 0 0 0 0.05 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1
Bud 0 1 1 0 1 5 4 2 9 11 11 5 2 1 0 1 0 2 0 0 1 3 0 3
Bud Neck 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 2 2
Bud Site 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 10 17 2 5 6 10 7 9 7 10 18 1 4 1 7 7 3 0 0 1 0 0 1
Cytoplasm 115 318 363 255 358 352 463 391 296 304 239 276 298 280 399 180 146 120 107 311 334 112 242 217
Endoplasmic Reticulum 0 5 1 1 0 0 0 0 0 1 0 3 2 1 1 9 3 3 1 2 3 13 16 7
Endosome 0 0 0 1 1 3 1 1 0 1 1 3 1 1 1 3 3 2 1 2 0 0 0 3
Golgi 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 2 1 1 0 0 1 0 0 1
Mitochondria 2 4 8 17 13 64 115 55 159 152 167 107 4 2 4 5 3 5 1 5 11 11 19 11
Nucleus 0 2 0 0 1 2 8 3 0 3 0 5 1 3 0 1 2 1 1 1 5 0 0 0
Nuclear Periphery 0 0 1 0 0 0 0 0 1 0 4 0 1 0 0 0 0 0 0 0 0 0 1 0
Nucleolus 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1
SpindlePole 0 0 0 0 0 0 2 4 0 0 0 1 0 0 0 1 0 0 0 0 2 0 0 0
Vac/Vac Membrane 0 0 11 2 9 9 4 21 15 17 14 14 0 1 1 13 8 11 2 6 4 6 16 7
Unique Cell Count 118 327 377 262 374 393 532 436 410 414 349 367 303 285 401 200 160 133 121 333 375 152 308 265
Labelled Cell Count 121 343 402 278 389 442 608 485 489 498 446 432 310 293 407 222 173 148 121 333 375 152 308 265


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 6.2 6.0 6.7 5.8 6.5 5.1 5.6 5.8 4.9 4.6 4.6 4.8 5.8 5.9 5.7 9.3 9.3 8.0 5.8 5.6 5.9
Std Deviation (1e-4) 0.8 0.9 1.4 1.1 1.7 1.0 1.3 1.5 1.0 1.0 1.1 0.8 0.9 1.0 0.9 1.8 1.4 1.8 1.5 1.5 1.1
Intensity Change (Log2) – – – -0.2 -0.03 -0.39 -0.26 -0.19 -0.46 -0.52 -0.55 -0.47 -0.19 -0.19 -0.23 0.47 0.47 0.27 -0.19 -0.24 -0.18

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP7000510WT3HU80HU120HU1600510WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30510WT1AF100AF140AF1800510
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery -2.7 -2.6 -2.4 -2.3 -2.4 0 0 0 0 -3.4 -2.3 -3.9 -0.6 -0.1 -1.2
Cytoplasm 0.7 -0.4 -3.6 -4.8 -3.6 -9.1 -8.8 -9.9 -8.3 1.6 1.5 3.2 -3.1 -2.4 -2.7
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 2.8 1.1 6.7 8.5 5.6 0 0 0 0 -0.8 0 -1.3 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole -1.9 -0.4 -0.5 -2.5 1.4 0.6 0.9 0.8 0.7 0 -2.5 -3.0 2.1 1.2 2.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 3.6331 4.5265 4.1086 3.921 3.9443 4.2656 1.7862 3.1311 2.569 3.0033 2.5073 2.8468 1.5297 2.3342 1.8593 2.3134 1.5656 2.1549
Actin 0.0346 0.0073 0.0155 0.0022 0.0055 0.0019 0.0228 0.0037 0.0126 0.0538 0.0142 0.0047 0.0223 0.0019 0.0128 0.0026 0.0003 0.0013
Bud 0.0007 0.0012 0.0005 0.0004 0.0123 0.0006 0.0005 0.0028 0.0003 0.0051 0.001 0.0014 0.0007 0.0013 0.0046 0.0023 0.0059 0.0022
Bud Neck 0.0042 0.0007 0.0058 0.0005 0.0005 0.009 0.0006 0.0004 0.0003 0.0026 0.0006 0.0011 0.003 0.0003 0.007 0.0005 0.001 0.0026
Bud Periphery 0.001 0.0009 0.0006 0.0004 0.0218 0.0014 0.0006 0.0019 0.0002 0.0059 0.0016 0.0015 0.0007 0.0006 0.0031 0.0042 0.003 0.0017
Bud Site 0.0163 0.0178 0.0046 0.001 0.0026 0.0003 0.0013 0.0072 0.0036 0.0211 0.0017 0.0003 0.003 0.0116 0.0085 0.0006 0.0016 0.0005
Cell Periphery 0.0011 0.0006 0.0004 0.0001 0.0003 0.0002 0.0003 0.0004 0.0002 0.0006 0.0002 0.0001 0.0006 0.0001 0.0004 0.0001 0.0003 0.0001
Cytoplasm 0.5472 0.8291 0.6976 0.794 0.7684 0.8349 0.7813 0.8953 0.9058 0.7182 0.637 0.8884 0.6343 0.8669 0.7419 0.7938 0.8208 0.8306
Cytoplasmic Foci 0.0283 0.0088 0.0147 0.0183 0.0055 0.0104 0.021 0.005 0.0085 0.0218 0.0553 0.0208 0.048 0.0192 0.0302 0.0239 0.0312 0.0215
Eisosomes 0.0004 0.0001 0.0002 0.0001 0 0.0001 0.0002 0 0.0002 0.0004 0.0001 0 0.0001 0 0.0003 0 0 0.0001
Endoplasmic Reticulum 0.0132 0.0023 0.0039 0.0047 0.0025 0.003 0.0117 0.0028 0.0052 0.0243 0.029 0.0059 0.0146 0.0027 0.0042 0.007 0.0042 0.007
Endosome 0.0304 0.0027 0.0125 0.0387 0.016 0.0073 0.0282 0.0031 0.0083 0.0459 0.0764 0.023 0.0487 0.0055 0.0158 0.0435 0.0224 0.0265
Golgi 0.0109 0.0011 0.006 0.0065 0.001 0.0019 0.0113 0.0004 0.0013 0.0148 0.0354 0.0042 0.013 0.0009 0.006 0.0041 0.0011 0.0044
Lipid Particles 0.0114 0.0004 0.0046 0.0142 0.0002 0.0014 0.0014 0.0001 0.0006 0.0059 0.0164 0.0006 0.0082 0.0003 0.0045 0.0003 0.0074 0.0024
Mitochondria 0.0144 0.0003 0.0076 0.0359 0.0009 0.0049 0.006 0.0001 0.0009 0.0386 0.0523 0.0164 0.0164 0.0004 0.0118 0.001 0.0008 0.0098
None 0.2522 0.1206 0.2113 0.0646 0.1291 0.1107 0.0836 0.0747 0.047 0.0127 0.0566 0.022 0.1462 0.0817 0.1294 0.0972 0.0843 0.083
Nuclear Periphery 0.0091 0.0005 0.0018 0.002 0.001 0.0042 0.0078 0.0004 0.001 0.0046 0.0038 0.0024 0.0036 0.0004 0.0011 0.0018 0.0012 0.0011
Nucleolus 0.0012 0.0001 0.0002 0.0005 0.0001 0.0001 0.0004 0 0.0001 0.0004 0.0002 0.0001 0.0006 0.0001 0.0004 0.0001 0.002 0.0001
Nucleus 0.0051 0.0016 0.0013 0.0019 0.0008 0.001 0.0083 0.0006 0.0012 0.0027 0.0016 0.001 0.0093 0.0013 0.0029 0.002 0.0036 0.0012
Peroxisomes 0.0113 0.0017 0.0042 0.0068 0.0001 0.0043 0.0032 0 0.0004 0.0095 0.0097 0.0007 0.0163 0.0026 0.0085 0.0029 0.0009 0.0009
Punctate Nuclear 0.003 0.0009 0.0031 0.0005 0.0002 0.001 0.0016 0.0001 0.0006 0.0019 0.0011 0.0003 0.0055 0.0005 0.0035 0.0006 0.0031 0.0006
Vacuole 0.0031 0.001 0.0026 0.005 0.0194 0.0011 0.0056 0.001 0.0014 0.0075 0.0038 0.0034 0.0042 0.0014 0.0026 0.0103 0.0046 0.0017
Vacuole Periphery 0.0009 0.0001 0.0009 0.0015 0.0116 0.0005 0.0024 0.0001 0.0003 0.0018 0.0022 0.0016 0.0007 0.0002 0.0005 0.0013 0.0006 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.9018 13.1358 5.0213 9.9211 6.6392 5.3404 14.0865 16.4343 10.8473 10.6293
Translational Efficiency 0.5253 0.9081 1.4691 0.5197 0.6781 0.5971 0.7801 0.5286 0.6016 0.5748

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
811 1632 1393 1095 1177 1996 1436 2484 1988 3628 2829 3579

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 737.24 827.40 1079.92 1056.65 667.82 802.61 911.06 1149.55 696.14 813.76 994.21 1121.13
Standard Deviation 83.10 114.06 136.11 133.76 115.93 100.58 127.51 163.27 109.26 107.56 156.53 160.65
Intensity Change Log 2 — 0.166451 0.550718 0.519291 — 0.265240 0.448087 0.783538 — 0.214249 0.502847 0.650932

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000184 0.000200 0.000360 0.001057 0.000171 0.000451 0.000069 0.001010 0.000177 0.000338 0.000212 0.001024
Bud Neck 0.015321 0.007498 0.003538 0.003383 0.005903 0.016997 0.003127 0.004405 0.009745 0.012724 0.003329 0.004092
Bud Site 0.008732 0.013911 0.013340 0.022623 0.008049 0.025195 0.005689 0.036453 0.008328 0.020119 0.009457 0.032222
Cell Periphery 0.000150 0.000060 0.000151 0.000123 0.000156 0.000090 0.000166 0.000069 0.000153 0.000077 0.000159 0.000085
Cytoplasm 0.534634 0.630721 0.606242 0.669565 0.568791 0.538071 0.532828 0.769257 0.554857 0.579748 0.568977 0.738756
Cytoplasmic Foci 0.264804 0.163003 0.020963 0.067359 0.205308 0.232341 0.054153 0.034325 0.229579 0.201150 0.037810 0.044432
Eisosomes 0.000164 0.000033 0.000030 0.000020 0.000085 0.000088 0.000086 0.000012 0.000117 0.000063 0.000059 0.000014
Endoplasmic Reticulum 0.001640 0.001122 0.003271 0.000762 0.001812 0.001044 0.001083 0.000227 0.001741 0.001079 0.002161 0.000391
Endosome 0.021947 0.017439 0.004325 0.010695 0.014603 0.023222 0.005915 0.004871 0.017599 0.020621 0.005132 0.006653
Golgi 0.004334 0.003472 0.000149 0.003619 0.003576 0.009557 0.000154 0.007704 0.003886 0.006820 0.000152 0.006454
Lipid Particles 0.006137 0.001851 0.001914 0.001245 0.007311 0.003146 0.002204 0.000725 0.006832 0.002564 0.002061 0.000884
Mitochondria 0.004397 0.002141 0.000483 0.001398 0.003783 0.005147 0.000263 0.002684 0.004034 0.003795 0.000371 0.002291
Mitotic Spindle 0.001483 0.007606 0.016327 0.031312 0.001372 0.004699 0.004936 0.044542 0.001417 0.006007 0.010545 0.040495
None 0.001563 0.001134 0.004087 0.001693 0.018078 0.000633 0.006773 0.002082 0.011341 0.000858 0.005450 0.001963
Nuclear Periphery 0.000158 0.000230 0.001763 0.000303 0.000538 0.000149 0.000701 0.000133 0.000383 0.000185 0.001224 0.000185
Nuclear Periphery Foci 0.000380 0.000579 0.004634 0.003311 0.001084 0.000293 0.001024 0.000707 0.000797 0.000422 0.002801 0.001504
Nucleolus 0.000331 0.000511 0.000292 0.000150 0.001747 0.000450 0.000492 0.000187 0.001170 0.000477 0.000393 0.000176
Nucleus 0.039831 0.037880 0.201447 0.025615 0.088831 0.034026 0.163842 0.028855 0.068841 0.035760 0.182359 0.027864
Peroxisomes 0.002531 0.002513 0.000232 0.002688 0.002056 0.006338 0.000746 0.004063 0.002250 0.004618 0.000493 0.003642
Vacuole 0.089454 0.104694 0.116174 0.151048 0.063963 0.094948 0.215187 0.054560 0.074362 0.099332 0.166433 0.084081
Vacuole Periphery 0.001824 0.003403 0.000279 0.002031 0.002783 0.003114 0.000562 0.003128 0.002392 0.003244 0.000423 0.002792

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.49 -7.78 -2.49 -2.42 -0.97 -3.85 2.90 -4.63 -0.80 -5.94 -3.77 -4.47 -4.96 -2.70 -3.69
Bud Neck 5.31 8.17 8.34 5.17 0.83 -10.40 5.10 3.19 12.96 -2.33 -3.41 9.38 8.59 13.54 -1.16
Bud Site -3.70 -0.78 -5.95 -3.05 -4.31 -9.46 1.59 -6.41 2.93 -8.00 -9.90 0.37 -8.48 0.46 -8.19
Cell Periphery 11.55 0.00 4.74 -4.78 4.54 5.11 1.28 9.51 4.04 10.01 9.47 1.03 11.44 1.28 11.88
Cytoplasm -8.12 4.43 -3.34 4.45 -8.14 2.85 5.13 -9.58 -14.28 -15.88 -3.22 7.10 -10.53 -8.33 -19.16
Cytoplasmic Foci 12.69 35.89 28.45 21.19 -14.70 -3.54 26.59 29.37 40.67 5.73 5.42 43.58 41.06 45.54 -5.28
Eisosomes 13.77 13.65 15.23 5.74 7.37 -0.35 2.02 18.49 14.67 15.22 10.04 12.43 22.43 16.02 17.56
Endoplasmic Reticulum 1.87 -7.37 4.40 3.58 15.18 2.46 3.02 6.59 4.19 8.63 3.11 -3.73 8.12 5.89 17.73
Endosome 2.41 10.63 8.93 8.93 -2.30 -5.65 8.89 11.94 17.61 4.80 -2.30 14.05 14.90 20.03 2.54
Golgi 1.74 9.46 4.49 3.40 -2.11 -7.48 8.48 1.50 7.32 -3.19 -5.65 12.46 3.14 7.22 -3.69
Lipid Particles 6.25 6.05 6.15 -0.25 0.68 6.12 8.31 9.55 5.77 2.66 8.75 10.34 11.46 5.34 3.28
Mitochondria 1.55 2.62 2.67 3.42 0.49 -1.11 3.72 2.86 5.27 -2.32 0.30 4.43 3.83 5.96 -1.75
Mitotic Spindle -3.30 -7.79 -7.93 -5.99 -2.75 -3.12 -4.31 -13.50 -11.99 -9.38 -4.54 -8.81 -15.61 -13.10 -8.87
None 0.72 -3.53 -0.30 -2.73 8.00 6.10 4.03 5.46 -14.52 2.77 6.09 3.61 5.28 -11.41 4.21
Nuclear Periphery -1.82 -27.67 -9.51 -5.37 23.06 4.38 -2.29 -0.77 -12.80 2.56 3.49 -18.30 -3.50 -12.55 19.39
Nuclear Periphery Foci -2.37 -15.74 -9.63 -8.94 2.12 6.27 -0.95 -1.45 -7.86 -0.52 4.46 -12.73 -8.05 -11.40 4.18
Nucleolus -1.65 0.19 1.56 2.42 1.71 4.21 4.37 4.55 0.44 0.85 3.74 4.42 4.59 1.56 0.86
Nucleus 0.41 -33.62 1.99 1.59 35.03 12.31 -8.67 8.61 -8.51 19.56 11.30 -27.21 7.98 -6.47 37.42
Peroxisomes 0.18 10.82 2.09 2.05 -5.08 -7.27 4.33 -0.37 7.10 -4.92 -6.65 8.83 0.68 6.98 -7.33
Vacuole -3.44 -12.67 -18.61 -17.19 -7.42 -7.83 -25.82 -20.65 -14.74 10.75 -8.13 -27.90 -26.61 -21.40 4.08
Vacuole Periphery -3.17 9.14 3.26 4.95 -1.58 -0.54 4.59 3.10 4.37 -1.31 -2.02 6.74 3.89 6.16 -1.97
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene
Localization
Cell Percentages cytoplasm (88%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YLL032C

YLL032C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Yll032c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available