Standard name
Human Ortholog
Description Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p; protein abundance increases in response to DNA replication stress
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Cytoplasm 0.98 0.97 0.97 0.98 0.96 0.88 0.79 0.79 0.71 0.69 0.66 0.65 0.99 0.99 0.98 0.97 0.97 – 0.88 0.9 0.78 0.74 0.79 0.78
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0.07 – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0.09 0.3 0.47 0.41 0.5 0.46 0.56 0.51 0 0 0 0.05 0 – 0 0 0.07 0.1 0.07 0.07
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 – 3 4 6 2 2 9
Bud 1 2 0 1 2 8 11 10 22 7 13 18 1 0 0 0 0 – 5 0 5 2 6 8
Bud Neck 1 5 2 0 1 4 3 5 3 4 2 7 6 2 2 0 2 – 1 0 0 2 3 4
Bud Site 0 0 0 0 0 0 0 2 1 2 3 3 0 0 0 0 0 – – – – – – –
Cell Periphery 3 1 3 3 1 0 3 1 2 1 2 2 3 5 6 7 12 – 1 2 3 6 2 3
Cytoplasm 483 339 293 259 358 352 353 469 288 293 336 346 449 565 608 361 330 – 439 302 229 201 265 354
Endoplasmic Reticulum 0 3 2 0 0 1 2 0 0 0 2 0 3 4 4 22 23 – 1 0 3 2 4 3
Endosome 1 0 1 0 1 0 1 0 4 0 1 2 1 0 2 5 2 – 2 2 3 1 5 3
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 2 – 0 2 2 2 3 3
Mitochondria 9 7 11 11 33 121 209 246 205 194 283 271 1 0 1 17 8 – 15 11 21 27 25 29
Nucleus 0 0 0 0 0 1 1 4 3 5 2 2 0 1 3 0 0 – 0 0 0 0 0 0
Nuclear Periphery 0 1 0 0 1 0 1 0 4 0 3 2 0 2 0 0 0 – 0 0 0 0 0 0
Nucleolus 2 0 1 0 0 1 0 1 2 2 1 1 0 0 0 0 0 – 1 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 2 1 0 1 1 0 0 0 0 0 – 0 0 1 0 0 1
SpindlePole 1 1 1 1 2 5 6 8 9 9 14 17 0 0 1 0 0 – 9 0 6 1 3 6
Vac/Vac Membrane 2 0 0 1 2 0 3 8 4 2 9 6 1 1 1 2 3 – 4 1 2 8 5 14
Unique Cell Count 493 348 302 263 372 400 448 594 408 422 507 531 455 571 618 374 339 498 334 295 271 336 453
Labelled Cell Count 503 360 314 276 401 493 593 756 548 519 672 678 466 580 630 415 382 498 334 295 271 336 453


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.9 3.7 3.5 3.6 3.4 3.3 2.9 3.1 2.8 2.8 2.6 2.7 5.5 5.3 5.6 5.1 5.1 4.8 5.4 5.8 5.6
Std Deviation (1e-4) 0.5 0.6 0.9 1.4 1.3 1.1 1.2 1.9 0.8 0.7 0.7 0.9 1.2 1.1 1.3 1.1 1.4 1.0 1.2 2.2 1.5
Intensity Change (Log2) – – – 0.03 -0.02 -0.07 -0.3 -0.16 -0.34 -0.31 -0.4 -0.39 0.65 0.61 0.69 0.54 0.53 0.47 0.64 0.73 0.68

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.9554 1.0819 1.1317 0.5978 1.0069 1.1556 1.9214 2.777 2.3032 1.6896 2.1144 2.6397 0.7644 1.5514 1.2101 1.1903 1.2512 1.3504
Actin 0.0114 0.0006 0.0221 0.002 0.0177 0.0114 0.0079 0.0005 0.0022 0.0009 0.0006 0.0041 0.011 0.0008 0.0047 0.0003 0.0245 0.0042
Bud 0.0024 0.0045 0.0032 0.0016 0.001 0.002 0.0021 0.0007 0.0034 0.0002 0.0038 0.0002 0.0003 0.001 0.001 0.0002 0.0006 0.0002
Bud Neck 0.0018 0.0007 0.0093 0.0004 0.0012 0.0078 0.0006 0.0002 0.0008 0.0001 0.0003 0.0005 0.0031 0.0002 0.0011 0.0004 0.0014 0.0009
Bud Periphery 0.0078 0.0027 0.0044 0.0021 0.0007 0.0029 0.0039 0.0005 0.0054 0.0004 0.0046 0.0003 0.0004 0.0008 0.002 0.0001 0.0006 0.0004
Bud Site 0.0069 0.0154 0.0126 0.0003 0.0039 0.0026 0.0038 0.0052 0.0033 0.0001 0.0007 0.0001 0.0025 0.003 0.0071 0.0009 0.0008 0.0002
Cell Periphery 0.0002 0.0003 0.0003 0.0001 0.0001 0.0002 0.0002 0.0002 0.0001 0.0001 0.0001 0 0.0001 0.0001 0.0002 0.0001 0.0001 0
Cytoplasm 0.2355 0.2823 0.2383 0.2918 0.2112 0.2682 0.2361 0.3449 0.2134 0.0945 0.3731 0.2911 0.3178 0.5338 0.3752 0.5241 0.4583 0.4875
Cytoplasmic Foci 0.0264 0.0085 0.0162 0.0088 0.023 0.0139 0.0116 0.0059 0.0154 0.0095 0.0055 0.0069 0.0117 0.0088 0.0067 0.0047 0.0321 0.01
Eisosomes 0.0002 0.0001 0.0003 0.0001 0.0001 0.0001 0.0003 0.0001 0.0002 0.0002 0 0.0001 0.0001 0 0.0001 0 0.0001 0.0001
Endoplasmic Reticulum 0.0029 0.0012 0.0015 0.0014 0.0011 0.002 0.0026 0.0009 0.0025 0.0009 0.0006 0.0008 0.0024 0.0016 0.0015 0.0021 0.0021 0.0015
Endosome 0.012 0.0016 0.0055 0.0024 0.0161 0.0044 0.006 0.0018 0.001 0.0032 0.0008 0.0016 0.0089 0.0019 0.0021 0.0029 0.012 0.0039
Golgi 0.0022 0.0002 0.0022 0.0005 0.0085 0.002 0.0013 0.0001 0.0002 0.0001 0.0001 0.0001 0.0018 0.0005 0.0004 0.0001 0.0046 0.0006
Lipid Particles 0.0043 0.0002 0.0022 0.0004 0.0307 0.0011 0.0011 0.0002 0.0002 0.0004 0.0001 0.0002 0.0025 0.0038 0.0004 0.0001 0.0032 0.0003
Mitochondria 0.0032 0.0004 0.0015 0.0013 0.0045 0.0015 0.0008 0.0003 0.0005 0.0002 0.0004 0.0002 0.0008 0.0004 0.0007 0.0005 0.0019 0.0006
None 0.6551 0.6694 0.6633 0.6304 0.6298 0.668 0.6983 0.6218 0.7399 0.8847 0.6048 0.6783 0.6159 0.4339 0.5874 0.4515 0.4259 0.4826
Nuclear Periphery 0.0041 0.0009 0.0017 0.0038 0.0076 0.0022 0.0085 0.0017 0.0009 0.0006 0.0004 0.0007 0.0046 0.0006 0.0012 0.0013 0.0073 0.0016
Nucleolus 0.0017 0.0008 0.0009 0.0016 0.0048 0.0004 0.0009 0.0005 0.0005 0.0002 0.0003 0.0002 0.0008 0.0002 0.0005 0.0004 0.0005 0.0001
Nucleus 0.0069 0.0048 0.0034 0.0126 0.0041 0.0022 0.0082 0.0026 0.0019 0.0008 0.0016 0.0016 0.0027 0.003 0.004 0.0046 0.0073 0.0025
Peroxisomes 0.0051 0.0002 0.0039 0.0268 0.0113 0.0032 0.0006 0.0003 0.0009 0.0002 0.0003 0.0004 0.0021 0.0027 0.0004 0.0001 0.0088 0.0007
Punctate Nuclear 0.007 0.0036 0.0061 0.0104 0.021 0.003 0.0037 0.0108 0.0066 0.0011 0.001 0.0123 0.0091 0.0019 0.0021 0.0046 0.0063 0.0016
Vacuole 0.0023 0.0014 0.001 0.0008 0.0009 0.0008 0.0012 0.0007 0.0005 0.0013 0.0008 0.0004 0.0011 0.0009 0.0012 0.0008 0.001 0.0005
Vacuole Periphery 0.0005 0.0002 0.0002 0.0003 0.0009 0.0002 0.0004 0.0001 0.0001 0.0002 0.0001 0.0001 0.0003 0.0001 0.0002 0.0003 0.0004 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 16.5039 11.2408 7.2985 11.4382 9.1706 20.4221 18.469 22.054 21.7727 15.2088
Translational Efficiency 1.1649 1.0491 1.2666 0.7243 0.6856 1.357 1.1866 0.9417 0.8241 0.7655

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1521 1570 320 1590 1567 1753 2096 1160 3088 3323 2416 2750

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 515.91 616.61 794.55 791.85 608.56 671.40 754.89 762.67 562.93 645.51 760.14 779.54
Standard Deviation 55.94 83.06 90.20 119.57 85.31 83.74 96.80 120.70 85.91 87.79 96.89 120.91
Intensity Change Log 2 — 0.257239 0.623019 0.618108 — 0.141773 0.310867 0.325659 — 0.195899 0.462502 0.467224

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000160 0.000278 0.000268 0.000896 0.000510 0.000302 0.000102 0.001584 0.000338 0.000291 0.000124 0.001186
Bud Neck 0.027698 0.031128 0.002150 0.015063 0.012741 0.057783 0.006606 0.007149 0.020108 0.045189 0.006016 0.011725
Bud Site 0.006082 0.010247 0.002514 0.076057 0.006084 0.025081 0.014906 0.030574 0.006083 0.018072 0.013264 0.056871
Cell Periphery 0.000555 0.000111 0.000164 0.000312 0.002493 0.000210 0.000111 0.000213 0.001538 0.000163 0.000118 0.000270
Cytoplasm 0.386397 0.431759 0.218895 0.406252 0.484646 0.346862 0.523434 0.494151 0.436253 0.386973 0.483097 0.443330
Cytoplasmic Foci 0.283195 0.218665 0.021415 0.016002 0.218788 0.258049 0.011278 0.035515 0.250512 0.239442 0.012621 0.024233
Eisosomes 0.000826 0.000115 0.000070 0.000046 0.000200 0.000203 0.000024 0.000063 0.000508 0.000162 0.000030 0.000053
Endoplasmic Reticulum 0.001811 0.000614 0.003497 0.004362 0.000943 0.000872 0.000653 0.001251 0.001371 0.000750 0.001030 0.003050
Endosome 0.007940 0.021601 0.003188 0.006437 0.010648 0.030850 0.001233 0.009993 0.009314 0.026480 0.001492 0.007937
Golgi 0.008044 0.002661 0.000100 0.006804 0.001484 0.009991 0.000152 0.004519 0.004715 0.006528 0.000145 0.005840
Lipid Particles 0.033709 0.010578 0.003118 0.001193 0.013896 0.012692 0.000567 0.001615 0.023655 0.011693 0.000905 0.001371
Mitochondria 0.042543 0.011492 0.000413 0.004592 0.003799 0.033528 0.001164 0.004254 0.022883 0.023117 0.001064 0.004449
Mitotic Spindle 0.000528 0.002191 0.000968 0.072949 0.000081 0.008021 0.017227 0.026444 0.000301 0.005266 0.015073 0.053332
None 0.011209 0.007363 0.006602 0.005854 0.007250 0.003465 0.006046 0.003972 0.009200 0.005307 0.006119 0.005060
Nuclear Periphery 0.000780 0.000696 0.001778 0.001738 0.000795 0.000548 0.001076 0.000927 0.000787 0.000618 0.001169 0.001396
Nuclear Periphery Foci 0.000278 0.000329 0.001103 0.000929 0.000373 0.000296 0.000210 0.000727 0.000326 0.000312 0.000329 0.000844
Nucleolus 0.002003 0.002746 0.001578 0.000829 0.002399 0.002130 0.000459 0.000487 0.002204 0.002421 0.000608 0.000685
Nucleus 0.155546 0.156485 0.685815 0.288249 0.187001 0.107803 0.380361 0.267430 0.171508 0.130803 0.420818 0.279467
Peroxisomes 0.014204 0.012803 0.000396 0.002933 0.004740 0.015987 0.000177 0.001611 0.009401 0.014483 0.000206 0.002375
Vacuole 0.014685 0.075887 0.045740 0.084336 0.040095 0.081178 0.033716 0.101942 0.027579 0.078678 0.035309 0.091763
Vacuole Periphery 0.001807 0.002253 0.000228 0.004169 0.001036 0.004149 0.000498 0.005579 0.001416 0.003253 0.000462 0.004764

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.43 -3.85 -6.25 -4.32 -2.86 0.67 1.35 -0.71 -1.11 -1.44 0.26 1.26 -1.46 -1.82 -2.40
Bud Neck -1.24 12.55 8.90 9.89 -6.46 -15.59 5.42 5.51 18.02 0.40 -12.55 12.05 10.03 20.06 -3.07
Bud Site -2.90 2.24 -8.93 -7.73 -9.97 -7.49 -2.69 -5.20 0.97 -3.39 -7.99 -2.72 -10.27 -4.72 -7.86
Cell Periphery 11.73 9.57 9.29 -4.29 -0.37 2.26 2.38 2.30 1.96 -4.36 2.69 2.81 2.67 -0.99 -5.62
Cytoplasm -4.34 14.21 5.55 9.37 -10.28 14.87 2.26 5.72 -6.83 3.92 7.55 1.09 9.00 1.86 6.96
Cytoplasmic Foci 8.24 44.46 49.72 39.09 3.44 -5.09 41.20 35.92 40.85 -10.89 2.08 63.07 60.59 57.10 -6.75
Eisosomes 13.41 13.85 14.59 12.84 5.00 -0.10 6.38 4.73 11.03 -10.53 11.34 15.78 14.90 15.06 -11.13
Endoplasmic Reticulum 4.09 -6.39 -3.36 -6.19 2.28 0.29 -1.03 -4.54 -5.27 -5.74 3.29 -1.70 -4.73 -7.21 -4.19
Endosome -8.63 5.44 6.22 12.28 0.92 -11.92 10.98 3.50 14.13 -5.13 -14.73 14.03 6.77 19.51 -6.38
Golgi 8.64 13.48 5.57 0.34 -2.61 -8.57 8.23 -1.17 6.01 -2.92 -2.88 14.90 3.55 5.20 -3.79
Lipid Particles 12.18 17.48 19.02 10.81 6.12 0.92 12.98 11.98 14.03 -8.20 10.36 22.58 22.16 17.67 -5.11
Mitochondria 10.20 14.62 13.75 7.57 -4.77 -11.92 4.89 1.67 12.44 -2.65 0.01 14.69 13.37 14.29 -4.28
Mitotic Spindle -2.84 -0.80 -11.09 -10.48 -10.81 -5.24 -7.57 -6.66 -3.75 -1.52 -5.88 -7.48 -12.92 -10.30 -6.14
None 2.52 3.08 4.18 1.82 0.02 2.89 1.27 3.09 0.13 5.00 3.87 3.73 4.97 1.21 2.47
Nuclear Periphery 0.37 -6.84 -10.99 -19.71 -6.05 2.42 -8.28 -6.35 -10.18 1.93 1.48 -8.38 -13.51 -22.36 -6.33
Nuclear Periphery Foci -0.92 -6.95 -7.67 -9.34 3.33 0.91 1.99 -3.81 -3.79 -5.27 0.24 -2.28 -8.35 -7.88 -7.08
Nucleolus -2.19 1.39 4.64 7.58 3.24 0.52 3.61 3.67 8.50 0.50 -0.79 5.13 5.37 11.00 0.95
Nucleus -0.24 -31.50 -24.11 -23.48 17.96 13.78 -30.98 -12.40 -22.48 13.08 9.46 -42.09 -26.11 -33.32 15.70
Peroxisomes 0.78 15.38 13.85 11.28 -2.35 -9.53 7.38 5.57 14.61 -3.47 -5.80 16.76 14.21 18.30 -4.37
Vacuole -20.64 -8.42 -28.77 -16.28 -9.17 -11.67 -5.26 -19.57 -13.02 -16.82 -22.11 -12.49 -33.84 -20.78 -23.90
Vacuole Periphery -1.54 11.86 0.47 1.10 -2.39 -7.40 2.44 -2.18 1.17 -3.00 -7.24 6.01 -1.48 1.97 -3.66
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p; protein abundance increases in response to DNA replication stress
Localization
Cell Percentages cytoplasm (18%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Gtt2

Gtt2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Gtt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available