Standard name
Human Ortholog
Description High-affinity S-methylmethionine permease; required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Cytoplasm 0.97 0.94 0.97 0.95 0.96 0.88 0.82 0.8 – 0.68 0.65 0.63 1.0 0.99 1.0 – – 0.93 0.84 0.81 0.68 0.74 0.76 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0.05 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Mitochondria 0 0.12 0 0.11 0.05 0.27 0.33 0.32 – 0.53 0.54 0.6 0 0 0 – – 0 0.05 0 0.17 0.12 0.11 0.06
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0.09 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 2 3 10 3 7 7
Bud 0 1 0 2 1 2 10 12 – 7 16 13 0 0 0 – – 2 1 2 5 3 8 10
Bud Neck 1 1 0 2 2 3 2 12 – 1 1 4 6 6 2 – – 1 0 1 5 0 2 3
Bud Site 0 0 0 0 0 0 1 0 – 2 0 4 0 0 0 – – 0 – – – – – –
Cell Periphery 1 0 3 4 2 0 1 1 – 1 2 2 3 3 2 – – 1 0 1 3 3 6 8
Cytoplasm 209 165 311 275 342 358 381 731 – 353 324 376 330 330 323 – – 170 190 156 214 202 368 369
Endoplasmic Reticulum 1 2 1 0 0 1 0 0 – 0 0 0 2 1 0 – – 10 1 0 5 5 3 3
Endosome 1 0 1 0 1 0 2 4 – 0 0 0 0 0 0 – – 1 3 1 1 3 4 2
Golgi 2 1 0 0 0 0 0 0 – 0 0 0 0 0 0 – – 0 3 0 0 2 1 1
Mitochondria 6 22 12 31 19 108 153 290 – 273 270 361 0 0 0 – – 8 11 8 52 31 51 28
Nucleus 0 1 1 2 3 0 2 9 – 2 2 2 2 2 1 – – 1 0 0 0 0 1 0
Nuclear Periphery 0 0 0 0 1 0 0 0 – 0 0 0 0 0 0 – – 0 0 0 0 2 0 0
Nucleolus 1 0 0 0 0 0 1 1 – 2 0 0 0 0 0 – – 0 0 0 0 0 0 1
Peroxisomes 0 0 0 0 1 0 1 0 – 0 0 0 0 0 0 – – 0 1 0 0 0 0 0
SpindlePole 0 0 1 2 1 4 9 22 – 9 15 13 0 0 0 – – 0 1 2 3 2 11 10
Vac/Vac Membrane 0 1 1 1 3 3 3 1 – 3 3 4 1 1 0 – – 17 5 6 3 5 6 8
Unique Cell Count 215 176 322 290 355 405 464 918 518 496 601 331 332 323 183 227 192 314 274 487 469
Labelled Cell Count 222 194 331 319 376 479 566 1083 653 633 779 344 343 328 211 227 192 314 274 487 469


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 3.8 3.6 3.6 3.6 3.0 2.7 3.0 – 2.4 2.5 2.4 5.2 5.2 5.3 4.2 4.7 5.4 5.2 5.1 5.1
Std Deviation (1e-4) 0.7 0.8 1.6 1.6 1.7 1.7 1.3 1.1 – 1.1 0.9 0.9 1.1 1.1 1.4 0.9 1.0 1.3 2.0 1.5 1.5
Intensity Change (Log2) – – – -0.0 0.02 -0.25 -0.41 -0.28 – -0.6 -0.54 -0.6 0.51 0.51 0.56 0.21 0.39 0.59 0.52 0.51 0.51

WT3RAP60RAP140RAP220RAP300RAP380RAP540RAP620RAP7000246WT3HU80HU120HU1600246WT3rpd3Δ_1rpd3Δ_2rpd3Δ_30246WT1AF100AF140AF1800246
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – 0
Bud Neck – – – – – – – – – – – – – – 0
Bud Site – – – – – – – – – – – – – – 0
Cell Periphery – – – – – – – – – – – – – – 0
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – 0
Endosome – – – – – – – – – – – – – – 0
Golgi – – – – – – – – – – – – – – 0
Mitochondria – – – – – – – – – – – – – – 0
Nuclear Periphery – – – – – – – – – – – – – – 0
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – 0
Peroxisomes – – – – – – – – – – – – – – 0
SpindlePole – – – – – – – – – – – – – – 0
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – 0
Cytoplasm – – – – – – – – – – – – – – 0
Nucleus – – – – – – – – – – – – – – 0
Vacuole – – – – – – – – – – – – – – 5.2

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.4698 0.8039 0.8093 0.5409 0.4842 0.662 1.9595 2.6279 1.9954 2.5897 0.8254 2.2226 0.9874 1.4161 1.2868 1.79 2.263 1.3517
Actin 0.0158 0.0011 0.001 0.0005 0.0006 0.0076 0.0012 0.0002 0.0013 0.0296 0.0003 0.017 0.0282 0.0005 0.0152 0.0002 0.028 0.0007
Bud 0.0186 0.0332 0.026 0.0507 0.0044 0.004 0.0002 0.0002 0 0 0.0004 0 0.0001 0 0.0014 0 0.0008 0
Bud Neck 0.0005 0.0005 0.0024 0.0006 0.0006 0.0013 0.0049 0.0001 0.0003 0.0001 0 0.0001 0.0001 0 0.0003 0.0001 0.0002 0.0001
Bud Periphery 0.0093 0.0063 0.0088 0.02 0.0018 0.0021 0.0001 0.0002 0.0001 0 0.0005 0.0001 0.0002 0 0.0012 0.0001 0.0007 0
Bud Site 0.0049 0.0353 0.0269 0.0112 0.0015 0.0006 0.005 0.01 0.0002 0.0002 0.0004 0 0.0004 0.0001 0.0076 0.0004 0.001 0
Cell Periphery 0.0008 0.0008 0.0008 0.0015 0.0002 0.0002 0.0002 0.0002 0.0001 0 0 0 0.0001 0.0001 0.0001 0.0001 0.0001 0
Cytoplasm 0.0574 0.0469 0.0524 0.0434 0.0592 0.0635 0.0179 0.1097 0.1226 0.0269 0.0383 0.0895 0.0723 0.0972 0.1043 0.1175 0.0849 0.08
Cytoplasmic Foci 0.0118 0.0061 0.0173 0.0037 0.0181 0.0173 0.0816 0.003 0.0032 0.0236 0.0025 0.0025 0.0093 0.0028 0.0074 0.0024 0.0082 0.0131
Eisosomes 0.0004 0.0004 0.0002 0.0002 0.0001 0.0003 0.0001 0.0003 0.0003 0.0002 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.003 0.0011 0.0021 0.0011 0.004 0.001 0.0001 0.0022 0.0014 0.0004 0.0004 0.0008 0.0066 0.0008 0.0034 0.0029 0.0009 0.0007
Endosome 0.0057 0.0008 0.0088 0.0001 0.0013 0.001 0.0039 0.0007 0.0064 0.0006 0.0003 0.0009 0.0254 0.0029 0.006 0.0014 0.0121 0.0009
Golgi 0.0013 0.0002 0.0006 0.0001 0.0002 0.0005 0.0051 0.0001 0.0003 0.0014 0.0001 0.0004 0.0147 0.0059 0.0013 0.0001 0.0621 0.001
Lipid Particles 0.0013 0.0004 0.001 0.0002 0.0008 0.0006 0.0039 0.0004 0.0005 0.0026 0.0002 0.0003 0.0059 0.0009 0.0022 0.0002 0.0004 0.0056
Mitochondria 0.002 0.0009 0.0013 0.0005 0.0008 0.0027 0.0005 0.0002 0.0008 0.0002 0.0003 0.0001 0.0019 0.0144 0.0009 0.0003 0.0201 0.0004
None 0.8417 0.8412 0.8079 0.8236 0.8767 0.8463 0.8122 0.8706 0.8401 0.893 0.9542 0.8869 0.8032 0.8722 0.838 0.8641 0.7786 0.8936
Nuclear Periphery 0.0067 0.001 0.003 0.0017 0.0012 0.0024 0.0001 0.0004 0.0174 0.0001 0.0002 0.0001 0.0227 0.0002 0.001 0.0032 0.0002 0.0002
Nucleolus 0.0013 0.002 0.0031 0.0025 0.0022 0.0029 0.0015 0.0001 0.0002 0 0.0002 0 0.0001 0 0.0001 0.0001 0 0
Nucleus 0.0088 0.0102 0.0119 0.0198 0.0063 0.0191 0.0011 0.0005 0.0021 0.0001 0.0003 0.0001 0.0016 0.0001 0.0006 0.0053 0.0002 0.0001
Peroxisomes 0.0017 0.0003 0.0005 0.0001 0.0005 0.0004 0.0564 0.0001 0.0002 0.0199 0.0002 0.0005 0.0019 0.0012 0.0072 0.0001 0.0006 0.003
Punctate Nuclear 0.0037 0.0105 0.0217 0.0152 0.0181 0.0251 0.0034 0.0005 0.001 0.0006 0.0009 0.0002 0.0007 0.0001 0.0005 0.0005 0.0001 0.0004
Vacuole 0.0024 0.0008 0.0019 0.0031 0.0011 0.0007 0.0008 0.0005 0.0006 0.0001 0.0002 0.0003 0.0017 0.0003 0.0008 0.0009 0.0004 0.0001
Vacuole Periphery 0.001 0.0001 0.0004 0.0003 0.0002 0.0002 0 0 0.001 0 0 0 0.0026 0.0001 0.0002 0.0002 0.0002 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 28.026 10.697 42.6126 50.5558 14.2898 13.8479 11.385 17.2892 34.7957 16.3733
Translational Efficiency 0.5796 0.8604 0.6586 0.5682 0.6321 0.9269 0.6516 0.6875 0.5832 0.5713

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
94 658 1522 1587 206 1807 2288 1706 300 2465 3810 3293

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 926.80 753.44 750.86 795.67 651.09 718.04 784.44 801.90 737.48 727.49 771.03 798.90
Standard Deviation 140.10 97.84 84.61 114.75 69.87 90.31 95.40 100.72 160.80 93.70 92.72 107.75
Intensity Change Log 2 — -0.298765 -0.303714 -0.220088 — 0.141207 0.268806 0.300565 — -0.100729 -0.039476 0.017883

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.003488 0.000349 0.000049 0.001057 0.000400 0.000335 0.000173 0.000421 0.001367 0.000338 0.000123 0.000728
Bud Neck 0.014557 0.032244 0.009900 0.008875 0.032095 0.048498 0.017384 0.007788 0.026600 0.044159 0.014394 0.008312
Bud Site 0.041263 0.009543 0.008641 0.033986 0.002977 0.014774 0.026359 0.035665 0.014973 0.013377 0.019281 0.034856
Cell Periphery 0.000481 0.000310 0.000102 0.000232 0.000239 0.000189 0.000148 0.000272 0.000315 0.000221 0.000129 0.000253
Cytoplasm 0.227964 0.371373 0.481420 0.469785 0.327811 0.382793 0.527500 0.496352 0.296526 0.379745 0.509093 0.483548
Cytoplasmic Foci 0.075006 0.268815 0.012423 0.022052 0.354571 0.270544 0.007042 0.022142 0.266974 0.270082 0.009192 0.022099
Eisosomes 0.000155 0.000176 0.000022 0.000050 0.000582 0.000267 0.000023 0.000045 0.000448 0.000243 0.000022 0.000047
Endoplasmic Reticulum 0.002724 0.000829 0.000578 0.001881 0.007636 0.000520 0.000767 0.001842 0.006097 0.000602 0.000691 0.001861
Endosome 0.028486 0.028147 0.001684 0.006585 0.032646 0.028964 0.002074 0.008232 0.031342 0.028746 0.001918 0.007438
Golgi 0.004303 0.002761 0.000134 0.005039 0.005205 0.006205 0.000359 0.004767 0.004922 0.005285 0.000269 0.004899
Lipid Particles 0.004244 0.010311 0.000536 0.001482 0.043299 0.011801 0.000538 0.000969 0.031061 0.011403 0.000538 0.001216
Mitochondria 0.001580 0.004874 0.001300 0.002941 0.007639 0.014578 0.002088 0.004932 0.005740 0.011988 0.001773 0.003972
Mitotic Spindle 0.013069 0.004757 0.009132 0.042030 0.000186 0.005953 0.018247 0.021093 0.004223 0.005634 0.014606 0.031183
None 0.001182 0.006158 0.005493 0.004643 0.000622 0.002375 0.008083 0.008887 0.000798 0.003385 0.007049 0.006841
Nuclear Periphery 0.000841 0.000829 0.001590 0.001597 0.000723 0.000416 0.001615 0.001173 0.000760 0.000526 0.001605 0.001378
Nuclear Periphery Foci 0.001482 0.000458 0.000106 0.000897 0.000598 0.000190 0.000152 0.000431 0.000875 0.000261 0.000133 0.000655
Nucleolus 0.000549 0.002096 0.000555 0.000514 0.000621 0.001556 0.000943 0.000749 0.000598 0.001700 0.000788 0.000636
Nucleus 0.211861 0.130299 0.435520 0.288494 0.090978 0.107046 0.347089 0.287675 0.128854 0.113253 0.382415 0.288070
Peroxisomes 0.003162 0.021275 0.000631 0.001018 0.019800 0.017127 0.000330 0.001158 0.014587 0.018235 0.000450 0.001090
Vacuole 0.361346 0.102506 0.029627 0.103482 0.070258 0.082619 0.037794 0.092276 0.161466 0.087928 0.034531 0.097677
Vacuole Periphery 0.002257 0.001892 0.000557 0.003362 0.001113 0.003250 0.001291 0.003132 0.001471 0.002888 0.000998 0.003243

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin 1.41 1.65 1.21 -1.47 -3.48 0.53 2.11 1.04 0.65 -2.24 1.49 2.02 1.24 -1.06 -3.87
Bud Neck -4.08 -0.08 0.30 8.12 1.36 -2.23 2.40 3.57 16.11 6.40 -3.52 2.35 3.45 17.87 5.94
Bud Site 2.16 2.40 0.74 -5.05 -6.11 -7.71 -8.09 -7.40 -1.77 -0.43 -0.84 -1.01 -3.06 -3.79 -3.44
Cell Periphery 0.49 2.50 1.85 0.90 -5.41 1.55 4.01 1.65 0.64 -1.22 1.18 4.19 2.60 1.18 -2.86
Cytoplasm -5.89 -8.87 -6.68 -1.00 5.40 -3.21 -6.64 -4.75 -2.89 3.33 -5.91 -10.21 -7.18 -2.32 6.29
Cytoplasmic Foci -17.07 5.99 5.50 29.09 -3.33 5.30 23.32 22.52 47.76 -9.70 -0.47 19.32 18.67 56.23 -10.01
Eisosomes -0.92 8.76 6.35 8.80 -17.31 4.15 7.60 7.24 10.05 -15.19 3.82 8.19 7.60 11.62 -22.80
Endoplasmic Reticulum 4.74 4.95 0.56 -11.36 -13.82 2.26 2.03 1.81 -4.24 -2.01 2.58 2.37 1.78 -9.28 -6.83
Endosome -1.52 3.83 3.35 8.88 -3.54 0.88 7.05 6.36 17.73 -4.71 0.05 7.97 7.20 19.98 -5.83
Golgi -0.15 1.79 0.24 0.64 -2.45 -0.90 5.20 2.70 4.69 -2.72 -1.02 5.36 2.43 4.68 -3.62
Lipid Particles -4.18 5.73 4.23 6.60 -9.03 4.70 6.42 6.35 14.86 -7.33 4.15 6.49 6.35 15.88 -11.47
Mitochondria -4.77 -0.35 -0.90 4.49 -0.89 -1.92 1.72 1.46 8.70 -1.03 -2.54 1.71 1.45 10.08 -1.25
Mitotic Spindle 0.41 -0.17 -3.17 -6.85 -5.88 -4.82 -8.59 -7.83 -4.20 -0.89 -1.52 -4.10 -7.55 -8.01 -4.96
None -2.46 -4.59 -5.12 1.05 1.38 -4.32 -8.13 -5.96 -3.70 0.50 -4.18 -9.46 -8.23 -2.08 1.33
Nuclear Periphery 1.21 -5.74 -8.43 -9.27 -4.18 2.64 -11.75 -9.85 -20.60 3.72 3.05 -13.06 -13.34 -21.43 -0.30
Nuclear Periphery Foci 4.02 5.50 2.17 -4.94 -11.03 3.58 3.62 0.83 -6.28 -6.22 5.40 6.37 1.38 -9.49 -12.41
Nucleolus -5.43 -1.60 -0.96 5.26 0.90 -6.32 -1.46 -0.60 5.06 0.63 -8.41 -1.81 -0.64 7.89 1.11
Nucleus 2.31 -9.77 -4.92 -22.26 13.64 -1.89 -33.58 -24.07 -31.84 10.24 0.93 -27.93 -18.44 -40.43 16.54
Peroxisomes -7.18 2.60 2.72 8.02 -0.11 0.59 4.60 4.49 13.12 -2.72 -1.23 4.71 4.61 15.38 -1.87
Vacuole 9.71 12.09 7.48 -8.76 -23.97 -1.58 1.78 -10.88 -14.02 -19.03 6.24 9.00 0.63 -18.04 -29.86
Vacuole Periphery -0.55 1.71 -0.01 0.71 -2.42 -4.67 0.79 -0.69 3.17 -1.15 -4.26 1.85 -0.61 3.35 -2.20
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description High-affinity S-methylmethionine permease; required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p
Localization
Cell Percentages ER (10%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Mmp1

Mmp1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mmp1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available