Standard name
Human Ortholog
Description S-methylmethionine-homocysteine methyltransferase; functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0.05 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0
Cytoplasm 0.98 0.98 0.96 1.0 0.99 0.97 0.91 0.91 0.85 0.87 0.78 0.81 0.98 0.99 0.99 0.98 0.97 0.97 0.7 0.78 0.7 0.8 0.78 0.83
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.08 0.06 0.07 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0.14 0.1 0.26 0.18 0.39 0.23 0 0 0 0 0 0 0.15 0.11 0.15 0.06 0.05 0.05
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 5 0 4 2
Bud 1 1 2 0 0 2 5 2 9 9 11 4 0 0 0 0 0 0 1 0 2 2 11 4
Bud Neck 3 1 11 11 18 12 8 15 7 10 1 7 3 2 3 2 2 3 1 0 1 1 1 5
Bud Site 0 1 0 0 0 0 3 1 1 1 2 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 3 1 1 2 0 0 1 2 0 0 1 0 3 4 2 12 6 4 2 0 2 0 3 2
Cytoplasm 267 158 262 275 362 308 317 292 380 395 309 224 194 318 418 222 300 214 207 133 173 106 214 268
Endoplasmic Reticulum 0 0 3 0 0 1 0 2 0 0 0 0 0 1 1 18 20 15 5 0 3 0 1 1
Endosome 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 4 3 2 3 3
Golgi 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 1 0 1 0 0 0 1
Mitochondria 8 2 3 1 1 22 47 32 118 80 156 64 0 0 1 5 7 7 43 19 36 7 13 15
Nucleus 0 0 0 1 0 0 2 5 0 0 3 2 2 0 1 1 3 2 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 1 0 0 0 0 1 0 1 0 0 0 0 0 1 0 1 0 0 0
Nucleolus 0 0 3 0 0 0 1 1 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 1 0 2 2 5 8 10 9 9 14 0 0 0 0 0 0 2 1 3 0 8 8
Vac/Vac Membrane 0 1 2 0 1 1 1 0 1 3 2 1 0 0 0 2 2 4 11 3 2 2 6 5
Unique Cell Count 273 161 274 276 365 319 347 321 449 455 398 276 197 320 421 226 309 221 297 172 248 132 277 325
Labelled Cell Count 282 167 289 290 384 349 390 360 526 507 495 316 203 326 426 263 346 252 297 172 248 132 277 325


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.2 4.2 4.5 4.3 4.4 3.3 3.2 3.9 3.0 3.2 2.9 3.3 4.6 4.7 4.7 5.6 6.1 5.5 4.6 4.8 5.3
Std Deviation (1e-4) 0.9 1.0 1.2 1.6 2.0 1.3 1.4 1.5 1.1 1.1 1.0 1.0 1.1 1.0 1.2 1.8 2.2 1.9 1.8 1.4 1.7
Intensity Change (Log2) – – – -0.08 -0.05 -0.44 -0.51 -0.19 -0.58 -0.48 -0.66 -0.45 0.03 0.06 0.07 0.31 0.43 0.29 0.02 0.08 0.23

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF100AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -0.2055 -1.0937 -0.9225 -0.767 -0.6404 -0.9873 -1.0838 -0.4003 -0.4691 -0.8075 -0.8936 -0.5999 -1.0535 -1.266 -0.9463 -0.4656 -1.2911 -1.2867
Actin 0.0288 0.0006 0.007 0.0242 0.0019 0.0027 0.0016 0.0001 0.0004 0.0001 0.0003 0.0006 0.02 0.0007 0.0134 0.0957 0.0064 0.0024
Bud 0.0033 0.0069 0.0055 0.0016 0.0011 0.0029 0.0042 0.0026 0.0029 0 0.0048 0.0062 0.0008 0.0035 0.0027 0.0014 0.0024 0.0002
Bud Neck 0.0153 0.0006 0.0012 0.0002 0.0002 0.0014 0.0005 0.0002 0.0011 0 0.0003 0.008 0.0009 0.0001 0.0058 0.0128 0.0003 0.0014
Bud Periphery 0.0098 0.0065 0.0033 0.008 0.002 0.0028 0.002 0.0009 0.0016 0 0.0016 0.0022 0.0015 0.0085 0.0017 0.0019 0.0045 0.0002
Bud Site 0.016 0.0225 0.0114 0.0042 0.001 0.0006 0.0087 0.0084 0.0081 0 0.0004 0.002 0.01 0.0041 0.0135 0.0018 0.0005 0.0003
Cell Periphery 0.0016 0.0003 0.0002 0.0002 0.0001 0.0001 0.0004 0.0002 0.0002 0 0.0001 0.0001 0.0002 0.0003 0.0008 0.0002 0.0001 0
Cytoplasm 0.0272 0.0121 0.0078 0.0301 0.0047 0.0177 0.0117 0.0158 0.0123 0.0147 0.0135 0.0173 0.0279 0.0564 0.0302 0.0239 0.054 0.0708
Cytoplasmic Foci 0.0323 0.0049 0.0116 0.01 0.0251 0.0103 0.0063 0.0031 0.0022 0.0022 0.0021 0.0049 0.0298 0.0047 0.0151 0.0129 0.0191 0.0028
Eisosomes 0.0009 0.0002 0.0003 0.0003 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0 0.0004 0.0001 0.0003 0.0003 0.0001 0.0002
Endoplasmic Reticulum 0.0057 0.0004 0.0004 0.004 0.0004 0.001 0.0004 0.0002 0.0003 0.0001 0.0002 0.0002 0.0032 0.0007 0.0023 0.0005 0.0009 0.0005
Endosome 0.0298 0.0004 0.0087 0.0077 0.0353 0.0059 0.0016 0.0002 0.0001 0.0004 0.0001 0.0001 0.0137 0.0008 0.0054 0.0047 0.0068 0.0019
Golgi 0.0094 0.0001 0.0019 0.0019 0.0186 0.002 0.0005 0 0.0001 0 0 0 0.0028 0.0001 0.0017 0.009 0.0022 0.001
Lipid Particles 0.0248 0.0003 0.0064 0.002 0.0483 0.0043 0.0022 0.0001 0.0002 0.0001 0.0001 0.0001 0.006 0.0003 0.0058 0.0031 0.005 0.001
Mitochondria 0.0127 0.0006 0.0025 0.0028 0.0084 0.005 0.0011 0.0003 0.0004 0.0001 0.0003 0.0002 0.0042 0.0006 0.0043 0.0015 0.001 0.001
None 0.7038 0.9302 0.9087 0.8819 0.8173 0.9236 0.9503 0.957 0.9475 0.9806 0.9537 0.9422 0.8113 0.9158 0.8694 0.8151 0.8365 0.9125
Nuclear Periphery 0.0113 0.0005 0.0026 0.0053 0.0008 0.0065 0.0005 0.0003 0.0006 0.0003 0.0008 0.0005 0.0262 0.0003 0.0065 0.0012 0.0022 0.0008
Nucleolus 0.0132 0.0011 0.0017 0.0008 0.0007 0.0006 0.0012 0.0009 0.0024 0.0001 0.0012 0.0009 0.0013 0.0003 0.0014 0.0004 0.0005 0.0002
Nucleus 0.0177 0.0043 0.003 0.0029 0.0006 0.0018 0.0016 0.0042 0.0058 0.0003 0.0127 0.0047 0.0099 0.0006 0.0053 0.0014 0.0013 0.0008
Peroxisomes 0.0147 0.0008 0.0089 0.0022 0.0294 0.001 0.0018 0.0001 0.0002 0.0001 0.0006 0.0002 0.0173 0.0002 0.0055 0.0031 0.0417 0.0006
Punctate Nuclear 0.0125 0.0062 0.0054 0.0085 0.0024 0.0083 0.0025 0.0048 0.0131 0.0007 0.0068 0.0092 0.0083 0.0011 0.0051 0.0082 0.013 0.0011
Vacuole 0.0073 0.0005 0.001 0.0008 0.0008 0.0008 0.0007 0.0003 0.0004 0.0001 0.0002 0.0002 0.0021 0.0008 0.003 0.0006 0.0011 0.0003
Vacuole Periphery 0.0018 0.0001 0.0005 0.0004 0.0008 0.0006 0.0001 0 0.0001 0 0.0001 0 0.0024 0.0001 0.0007 0.0002 0.0004 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 9.6194 7.0817 16.5154 28.7735 8.8038 12.4418 4.603 10.3558 17.298 9.6267
Translational Efficiency 1.1864 1.0297 1.1663 1.0675 0.9936 0.832 1.5201 1.0051 1.2318 0.7841

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
262 778 2638 1395 2004 2138 680 1300 2266 2916 3318 2695

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 661.66 620.61 764.35 720.64 617.45 655.66 806.95 736.88 622.56 646.31 773.08 728.47
Standard Deviation 68.66 99.61 92.91 116.08 69.27 86.69 98.34 107.65 70.63 91.64 95.61 112.38
Intensity Change Log 2 — -0.092403 0.208143 0.123189 — 0.086626 0.386157 0.255107 — -0.003207 0.296818 0.188375

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000140 0.000456 0.000098 0.000943 0.000099 0.000413 0.000165 0.000451 0.000104 0.000424 0.000112 0.000706
Bud Neck 0.023092 0.045783 0.006406 0.011224 0.016662 0.050657 0.002418 0.007566 0.017405 0.049356 0.005589 0.009459
Bud Site 0.003172 0.022044 0.008816 0.053694 0.003390 0.019277 0.004324 0.025014 0.003365 0.020015 0.007896 0.039859
Cell Periphery 0.000181 0.000167 0.000109 0.000536 0.000125 0.000154 0.000187 0.000158 0.000132 0.000158 0.000125 0.000354
Cytoplasm 0.381186 0.371467 0.354056 0.472088 0.467509 0.353241 0.332838 0.523358 0.457528 0.358104 0.349708 0.496819
Cytoplasmic Foci 0.302864 0.280428 0.004410 0.027266 0.225308 0.261174 0.021179 0.021843 0.234275 0.266311 0.007846 0.024650
Eisosomes 0.000250 0.000158 0.000016 0.000064 0.000182 0.000168 0.000068 0.000039 0.000190 0.000165 0.000026 0.000052
Endoplasmic Reticulum 0.000762 0.001017 0.001152 0.002142 0.000793 0.000782 0.002370 0.001190 0.000790 0.000845 0.001401 0.001683
Endosome 0.014099 0.032433 0.000699 0.005132 0.006366 0.029577 0.002904 0.003441 0.007260 0.030339 0.001151 0.004316
Golgi 0.001419 0.008884 0.000046 0.003771 0.002529 0.008143 0.000081 0.003900 0.002400 0.008341 0.000054 0.003834
Lipid Particles 0.012698 0.011248 0.000400 0.001448 0.009850 0.009384 0.002260 0.000995 0.010180 0.009882 0.000781 0.001229
Mitochondria 0.011122 0.016207 0.000827 0.003281 0.005763 0.024746 0.000564 0.001854 0.006382 0.022468 0.000773 0.002593
Mitotic Spindle 0.000126 0.004059 0.003968 0.020800 0.001065 0.010054 0.004206 0.017165 0.000957 0.008455 0.004017 0.019046
None 0.001769 0.009481 0.004710 0.003692 0.002504 0.003230 0.010807 0.009578 0.002419 0.004898 0.005960 0.006531
Nuclear Periphery 0.000799 0.000470 0.001663 0.001527 0.000430 0.000496 0.001681 0.001123 0.000472 0.000489 0.001667 0.001332
Nuclear Periphery Foci 0.000500 0.000538 0.000165 0.001574 0.000182 0.000353 0.001109 0.000541 0.000219 0.000402 0.000359 0.001076
Nucleolus 0.001252 0.002849 0.000367 0.000475 0.000889 0.002384 0.001226 0.000565 0.000931 0.002508 0.000543 0.000518
Nucleus 0.190639 0.099311 0.594916 0.291121 0.222799 0.118836 0.553345 0.301770 0.219081 0.113627 0.586396 0.296258
Peroxisomes 0.012084 0.024913 0.000138 0.000673 0.006196 0.025246 0.000361 0.002026 0.006877 0.025157 0.000184 0.001326
Vacuole 0.040687 0.064414 0.016840 0.094340 0.026763 0.078798 0.057619 0.075940 0.028373 0.074960 0.025198 0.085465
Vacuole Periphery 0.001159 0.003672 0.000198 0.004209 0.000596 0.002887 0.000286 0.001482 0.000661 0.003097 0.000216 0.002894

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.48 0.52 -1.83 -0.70 -1.91 -6.43 -4.24 -3.50 0.91 -1.10 -8.36 -2.97 -2.69 -0.50 -2.38
Bud Neck -3.76 3.41 2.88 9.29 -1.80 -13.87 11.44 7.39 18.85 -3.48 -14.52 9.08 7.34 20.60 -1.99
Bud Site -7.96 -3.27 -8.32 -3.11 -6.98 -10.36 -0.84 -5.85 1.06 -4.86 -12.82 -3.90 -10.16 -2.43 -7.90
Cell Periphery 0.79 4.43 -1.52 -1.67 -2.21 -3.34 -5.06 -0.15 2.66 4.43 -3.29 1.50 -1.92 -1.48 -2.11
Cytoplasm 0.64 3.65 -1.54 -2.99 -9.19 13.92 16.84 4.01 -7.65 -12.06 13.56 20.55 5.31 -7.99 -14.61
Cytoplasmic Foci 1.49 22.21 20.72 31.85 -12.80 -5.31 41.65 42.50 48.93 0.05 -5.25 50.19 46.53 58.03 -13.25
Eisosomes 3.62 9.87 7.62 7.76 -8.71 1.19 9.98 14.64 13.79 7.33 2.35 18.88 14.91 14.48 -8.38
Endoplasmic Reticulum -0.64 -2.59 -4.92 -6.02 -5.11 0.06 -12.36 -9.73 -8.54 5.78 -0.42 -10.65 -11.94 -10.70 -2.89
Endosome -5.29 5.51 4.23 11.72 -5.65 -16.91 7.25 8.23 19.96 1.70 -18.59 13.82 7.97 22.69 -6.04
Golgi -6.42 3.99 -0.65 4.92 -2.37 -7.82 7.76 0.74 5.90 -2.16 -9.47 8.33 0.73 7.86 -3.22
Lipid Particles 0.61 5.28 4.82 8.12 -12.49 0.54 12.65 15.58 14.34 7.40 0.40 16.56 15.74 16.18 -6.66
Mitochondria -0.86 1.87 1.60 6.59 -1.86 -10.45 6.40 5.34 14.33 -2.10 -9.92 5.90 4.54 15.23 -2.31
Mitotic Spindle -2.95 -5.17 -7.31 -4.52 -5.15 -5.99 -2.24 -5.40 -0.78 -2.57 -6.41 -4.32 -8.67 -3.20 -5.88
None -3.68 -5.81 -3.28 2.99 3.54 -1.61 -5.68 -4.76 -3.54 1.26 -3.69 -7.18 -4.99 0.10 0.62
Nuclear Periphery 0.89 -3.67 -3.95 -13.28 -1.20 -1.00 -16.21 -18.24 -14.60 2.30 -0.27 -24.98 -19.48 -18.94 0.19
Nuclear Periphery Foci -0.25 1.40 -3.04 -3.49 -4.96 -2.76 -9.10 -5.62 -3.50 3.29 -3.44 -5.77 -6.84 -5.02 -4.63
Nucleolus -4.12 3.68 3.52 7.29 -0.65 -5.00 -1.06 2.82 6.19 3.76 -6.52 3.94 4.40 8.62 0.71
Nucleus 7.14 -34.25 -10.02 -24.80 32.92 18.41 -28.57 -15.07 -28.48 15.76 20.62 -59.71 -17.98 -37.78 37.56
Peroxisomes -4.36 5.66 5.52 11.58 -2.38 -12.71 11.56 6.92 16.01 -1.23 -14.26 13.02 10.67 20.27 -1.89
Vacuole -5.22 4.31 -18.41 -14.46 -23.48 -19.09 -11.94 -20.73 -10.48 -4.97 -20.51 -6.37 -30.50 -17.32 -25.91
Vacuole Periphery -3.69 2.26 -1.22 1.31 -2.52 -9.90 4.42 -0.50 5.10 -1.54 -10.83 6.94 -1.91 2.93 -2.94
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description S-methylmethionine-homocysteine methyltransferase; functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
Localization
Cell Percentages cytoplasm (13%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Mht1

Mht1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Mht1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available