ORF
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.05 0 0.06 0.09 0.11 0.21 0.2 0.25 0.29 – 0.21 0.26 0 0 0 0.09 0.13 0.14 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0.05 0 0 – 0 0.08 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0.05 0.19 0.14 0.12 0.1 0.07 – 0.07 0.07 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.06 0 0 0 0 0 0 0
Mitochondria 0.1 0.1 0 0.1 0 0.13 0.13 0.11 0.32 – 0.36 0.22 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0.08 0.16 0.12 0.05 0 0 0.05 0 0 – 0 0 0.07 0 0.05 0.05 0.05 0.05 0 0.05 0 0.05 0 0
Nuclear Periphery 0.16 0.07 0.05 0 0 0 0 0 0 – 0 0 0.09 0.1 0.11 0.07 0 0.07 0.13 0 0.07 0 0.06 0.06
Nucleolus 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0.05 0 0 0.05 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.81 0.81 0.86 0.8 0.69 0.62 0.54 0.58 0.41 – 0.48 0.47 0.87 0.93 0.9 0.83 0.81 0.79 0.75 0.84 0.82 0.86 0.83 0.8
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 3 0 7 2 1 – 3 6 0 0 0 1 0 1 0 1 1 0 0 0
Bud 0 1 1 1 4 6 8 10 9 – 11 9 1 0 0 0 0 0 0 0 0 0 4 6
Bud Neck 0 0 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 1 0 0 1 5 8 3 – 0 5 0 0 0 0 1 2 0 0 0 0 0 0
Cytoplasm 8 3 16 15 30 72 103 91 92 – 66 112 16 13 20 17 16 21 1 1 3 0 0 1
Endoplasmic Reticulum 1 0 1 1 6 4 27 13 11 – 12 32 2 2 3 7 1 4 0 0 2 0 4 3
Endosome 1 0 2 9 53 46 59 38 24 – 23 28 3 8 9 6 0 4 4 3 8 11 20 23
Golgi 0 2 0 0 0 1 7 2 2 – 0 2 0 3 0 8 8 5 1 0 2 0 0 4
Mitochondria 15 14 10 17 11 45 69 39 102 – 113 94 15 4 15 7 3 3 1 1 8 2 4 5
Nucleus 13 23 33 8 9 7 24 15 9 – 8 15 30 19 30 9 6 7 5 8 6 15 16 17
Nuclear Periphery 25 10 13 5 2 4 11 3 7 – 7 3 37 54 72 12 1 11 21 4 20 5 29 32
Nucleolus 3 4 0 2 6 9 16 1 4 – 9 4 3 5 6 3 2 4 1 0 0 2 3 3
Peroxisomes 0 0 0 0 0 2 0 1 0 – 0 2 0 0 1 0 0 0 0 0 0 0 1 0
SpindlePole 0 0 0 0 15 11 19 17 8 – 10 10 0 0 0 2 0 1 0 1 0 0 1 2
Vac/Vac Membrane 125 119 243 132 195 208 274 214 132 – 151 200 374 498 570 152 101 118 126 129 253 266 437 410
Unique Cell Count 154 147 282 164 281 336 512 370 322 317 424 429 537 630 183 125 149 168 155 311 309 527 515
Labelled Cell Count 191 176 320 190 334 416 629 454 404 413 523 481 606 726 224 139 181 168 155 311 309 527 515


Vacuole Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.8 7.8 7.7 6.8 7.6 6.6 6.8 7.0 6.2 – 6.1 6.4 8.7 8.9 9.0 12.5 12.5 12.5 7.3 7.6 8.4
Std Deviation (1e-4) 1.4 1.9 1.1 1.2 1.3 1.5 1.3 1.3 1.1 – 1.3 1.4 5.0 1.4 1.6 3.1 3.0 3.4 1.5 1.5 1.9
Intensity Change (Log2) – – – -0.19 -0.01 -0.22 -0.19 -0.15 -0.31 – -0.35 -0.26 0.17 0.2 0.22 0.7 0.7 0.7 -0.07 -0.02 0.12


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 2.7 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 1.4 2.2 5.6 5.5 6.5 7.3 – 5.4 7.0 -1.2 -2.4 -1.8 1.5 2.5 3.0
Endoplasmic Reticulum 0 0 0 3.6 2.8 2.7 – 2.9 4.4 0 0 0 0 0 0
Endosome 0 7.3 6.0 5.5 5.0 4.1 – 4.0 3.8 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 2.9 0.2 4.3 4.5 3.4 8.9 – 9.7 6.8 0 0 -1.0 0.2 0 0
Nucleus -2.4 -3.8 -4.8 -3.7 -3.7 -4.3 – -4.4 -4.2 -2.2 -4.6 -3.8 -2.5 -2.2 -2.4
Nuclear Periphery -0.8 -2.9 -2.6 -1.9 -3.1 -1.7 – -1.6 -3.4 2.0 2.7 3.3 0.9 0 1.2
Nucleolus 0 0 0 3.0 0 0 – 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
SpindlePole 0 3.9 3.1 3.3 3.6 0 – 0 0 0 0 0 0 0 0
Vacuole -1.6 -4.8 -6.8 -9.2 -7.8 -11.4 – -9.9 -10.5 0.4 3.0 1.9 -0.9 -1.4 -1.9

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.8362 3.7443 3.3398 2.8605 3.2647 3.0245 2.3198 2.6133 2.2779 2.1973 1.9469 2.1996 3.7329 3.2058 3.6895 3.2604 2.9808 3.2226
Actin 0.0369 0.0003 0.0009 0.0049 0 0.0012 0.0044 0 0.0012 0.001 0.0016 0.0031 0.0002 0 0.0001 0 0 0.0001
Bud 0.0005 0.0002 0.0004 0.0003 0.0001 0.0002 0.0005 0.0002 0.0011 0.0007 0.0002 0.0002 0.0003 0.0023 0.0011 0.0003 0.0003 0.0011
Bud Neck 0.0008 0.0007 0.0003 0.0004 0.0001 0.0003 0.0012 0.0002 0.0005 0.0002 0.0003 0.0003 0.0006 0.0012 0.0013 0.0002 0.0005 0.0008
Bud Periphery 0.0013 0.0006 0.0011 0.0007 0.0003 0.0007 0.001 0.0005 0.0009 0.0004 0.0007 0.0007 0.0011 0.0033 0.0023 0.0017 0.0009 0.0017
Bud Site 0.0028 0.0011 0.0006 0.0013 0.0001 0.0002 0.0029 0.0002 0.0027 0.0005 0.0013 0.0002 0.0008 0.0042 0.0029 0.0001 0.0003 0.0005
Cell Periphery 0.0022 0.0014 0.001 0.0005 0.0004 0.0009 0.0014 0.0005 0.0005 0.0002 0.0005 0.0004 0.0021 0.0013 0.0021 0.0051 0.0007 0.0012
Cytoplasm 0.0056 0.0058 0.0045 0.003 0.0037 0.0012 0.0059 0.0092 0.0022 0.0039 0.0007 0.0014 0.0028 0.0084 0.0095 0.0006 0.0042 0.0059
Cytoplasmic Foci 0.0103 0.0054 0.0064 0.0125 0.0065 0.0011 0.0219 0.0013 0.0078 0.05 0.002 0.0044 0.0061 0.0044 0.014 0.0012 0.0231 0.0112
Eisosomes 0.0002 0 0.0001 0.0006 0 0 0.0001 0 0.0001 0 0.0003 0 0.0001 0 0.0001 0 0 0
Endoplasmic Reticulum 0.0054 0.0073 0.0035 0.0023 0.0027 0.0059 0.0037 0.0042 0.0015 0.0006 0.0016 0.0018 0.0018 0.0041 0.0033 0.0009 0.0016 0.002
Endosome 0.1247 0.1105 0.1511 0.1506 0.2301 0.1123 0.1728 0.0912 0.131 0.1376 0.0973 0.1134 0.1114 0.1305 0.1611 0.1644 0.2032 0.1123
Golgi 0.0136 0.0025 0.0057 0.0202 0.0029 0.0101 0.0128 0.0011 0.0115 0.007 0.0043 0.005 0.003 0.0027 0.004 0.0025 0.0046 0.0026
Lipid Particles 0.0115 0.0055 0.0215 0.0343 0.0063 0.0058 0.0121 0.0007 0.0036 0.0045 0.0137 0.007 0.0147 0.0033 0.0155 0.0186 0.0047 0.0174
Mitochondria 0.0324 0.0092 0.0454 0.0184 0.0051 0.0417 0.0174 0.0081 0.0347 0.0263 0.0424 0.0152 0.0598 0.0049 0.0462 0.0191 0.0243 0.0174
None 0.0162 0.0075 0.037 0.0865 0.0004 0.0003 0.0012 0.0004 0.0004 0.0004 0.001 0.0006 0.0046 0.0091 0.0222 0.0001 0.0012 0.0094
Nuclear Periphery 0.0198 0.0244 0.0133 0.0076 0.0076 0.0285 0.0175 0.0167 0.0169 0.0028 0.0085 0.0158 0.0064 0.0138 0.012 0.0045 0.0054 0.0364
Nucleolus 0.004 0.0032 0.0025 0.0018 0.0003 0.0006 0.0025 0.0005 0.0019 0.0023 0.0019 0.0008 0.0183 0.0264 0.0164 0.0015 0.0041 0.0183
Nucleus 0.0074 0.0046 0.0102 0.0016 0.0009 0.0028 0.0029 0.0022 0.0065 0.0011 0.0012 0.0019 0.0387 0.0197 0.0215 0.0017 0.0039 0.0187
Peroxisomes 0.019 0.0004 0.005 0.0067 0.0002 0.0004 0.0029 0.0001 0.0014 0.0015 0.0052 0.0004 0.0032 0.0005 0.0015 0.0011 0.0012 0.0016
Punctate Nuclear 0.0034 0.0003 0.0009 0.001 0.0001 0 0.0017 0 0.0001 0.0077 0.001 0.0004 0.0004 0.0008 0.0026 0 0.0001 0.0029
Vacuole 0.4465 0.479 0.3788 0.4095 0.3933 0.3552 0.4275 0.4721 0.4035 0.3948 0.39 0.3478 0.4237 0.4602 0.389 0.3922 0.4178 0.341
Vacuole Periphery 0.2355 0.3303 0.3099 0.2352 0.3391 0.4305 0.2856 0.3907 0.3701 0.3563 0.4241 0.4791 0.2999 0.2988 0.2711 0.3844 0.2979 0.3975

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 6.1797 5.3338 7.0677 12.7695 7.1835 8.5191 10.4008 10.3998 13.7751 12.7793
Translational Efficiency 0.8241 0.6689 0.8946 0.463 0.6662 0.7291 0.6493 0.4944 0.5695 0.6087

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✔
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1748 1504 139 1213 1501 1925 169 102 3249 3429 308 1315

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 756.03 943.60 1463.79 956.25 897.69 965.22 1165.74 1190.89 821.48 955.74 1300.25 974.45
Standard Deviation 102.16 159.18 184.96 136.69 127.70 149.96 133.62 235.15 134.67 154.45 217.33 159.57
Intensity Change Log 2 — 0.319732 0.953193 0.338944 — 0.104640 0.376957 0.407751 — 0.206966 0.669090 0.376701

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000015 0.000025 0.000305 0.000256 0.000044 0.000066 0.000175 0.000026 0.000028 0.000048 0.000234 0.000238
Bud Neck 0.002077 0.000882 0.015243 0.007362 0.000629 0.000549 0.020376 0.003106 0.001408 0.000695 0.018060 0.007032
Bud Site 0.009768 0.004619 0.004108 0.018183 0.003108 0.002511 0.009036 0.007660 0.006691 0.003436 0.006812 0.017367
Cell Periphery 0.000223 0.000194 0.000085 0.000131 0.000102 0.000176 0.000104 0.000048 0.000167 0.000184 0.000095 0.000124
Cytoplasm 0.021031 0.008515 0.000393 0.013449 0.006749 0.001789 0.002263 0.011816 0.014433 0.004739 0.001419 0.013322
Cytoplasmic Foci 0.012278 0.003474 0.002367 0.009270 0.005874 0.003559 0.001913 0.011289 0.009320 0.003522 0.002118 0.009427
Eisosomes 0.000008 0.000005 0.000032 0.000014 0.000004 0.000005 0.000044 0.000004 0.000006 0.000005 0.000039 0.000013
Endoplasmic Reticulum 0.002568 0.001550 0.001678 0.003211 0.001702 0.001365 0.003763 0.000744 0.002168 0.001446 0.002822 0.003020
Endosome 0.039603 0.013830 0.008060 0.053471 0.019057 0.013349 0.031456 0.024074 0.030111 0.013560 0.020898 0.051190
Golgi 0.004457 0.001928 0.003686 0.006569 0.002153 0.003071 0.001972 0.004712 0.003393 0.002569 0.002746 0.006425
Lipid Particles 0.000587 0.000490 0.000479 0.001153 0.000390 0.000764 0.000951 0.000359 0.000496 0.000644 0.000738 0.001092
Mitochondria 0.013588 0.003093 0.003404 0.005794 0.003058 0.007836 0.002190 0.000192 0.008723 0.005756 0.002738 0.005359
Mitotic Spindle 0.000282 0.000325 0.008345 0.008401 0.000154 0.000155 0.001209 0.001262 0.000223 0.000229 0.004429 0.007847
None 0.000848 0.000259 0.000168 0.000710 0.000130 0.000101 0.000217 0.000042 0.000517 0.000170 0.000195 0.000658
Nuclear Periphery 0.000198 0.001362 0.025652 0.002854 0.000574 0.000715 0.005317 0.000704 0.000372 0.000999 0.014494 0.002687
Nuclear Periphery Foci 0.000098 0.000337 0.009944 0.003247 0.000288 0.000260 0.002684 0.001295 0.000186 0.000294 0.005961 0.003096
Nucleolus 0.000471 0.000691 0.048506 0.004706 0.000573 0.000546 0.047160 0.000920 0.000518 0.000610 0.047768 0.004413
Nucleus 0.002664 0.002060 0.036716 0.011276 0.002466 0.000944 0.068223 0.001968 0.002573 0.001433 0.054004 0.010554
Peroxisomes 0.000409 0.000287 0.002043 0.000887 0.000224 0.000452 0.002459 0.000416 0.000324 0.000379 0.002271 0.000851
Vacuole 0.371727* 0.324642* 0.294484* 0.698921* 0.371949* 0.320813* 0.530149* 0.695510* 0.371829* 0.322493* 0.423794* 0.698656*
Vacuole Periphery 0.517098* 0.631432* 0.534303* 0.150135* 0.580771* 0.640974* 0.268338* 0.233854* 0.546514* 0.636789* 0.388367* 0.156629*

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -2.00 -3.66 -3.65 -3.46 0.95 -0.59 -3.29 0.93 1.15 3.93 -0.99 -4.85 -3.41 -2.95 0.39
Bud Neck 3.73 -5.01 -8.35 -10.47 2.83 0.21 -6.84 -3.52 -3.63 5.76 3.40 -8.40 -9.78 -11.05 5.05
Bud Site 4.24 3.51 -3.57 -5.79 -5.47 0.72 -2.92 -1.49 -1.65 0.40 4.53 -0.45 -5.06 -6.60 -4.22
Cell Periphery 0.67 5.31 3.41 1.71 -2.30 -3.89 -0.11 3.81 6.88 2.83 -0.75 4.08 2.35 2.76 -1.44
Cytoplasm 4.87 10.48 1.92 -3.32 -9.92 3.72 2.30 -1.89 -3.69 -3.17 6.75 9.08 -0.79 -6.68 -8.67
Cytoplasmic Foci 8.93 8.76 2.28 -5.15 -5.46 2.03 3.94 -1.69 -2.45 -3.01 7.63 9.69 -0.10 -5.65 -7.05
Eisosomes 3.81 -4.28 -4.96 -7.85 3.27 -1.32 -7.90 -0.70 0.51 7.71 1.80 -8.53 -7.09 -7.85 6.52
Endoplasmic Reticulum 2.64 1.33 -1.26 -4.01 -2.38 1.65 -3.61 3.25 2.22 4.99 3.23 -1.83 -2.16 -4.44 -0.12
Endosome 10.72 11.51 -3.91 -13.44 -14.07 3.04 -3.01 -1.42 -3.07 1.36 10.65 3.30 -7.32 -14.46 -8.67
Golgi 4.37 0.62 -1.86 -4.38 -1.85 -1.15 0.33 -1.73 -1.03 -1.93 1.60 1.04 -3.08 -3.83 -3.45
Lipid Particles 0.34 0.23 -1.70 -1.69 -1.80 -1.25 -2.40 -0.11 1.18 2.28 -0.79 -1.86 -1.99 -1.24 -0.99
Mitochondria 7.27 7.02 4.39 -2.09 -1.81 -3.52 1.17 4.86 6.25 4.17 2.78 6.95 2.60 0.39 -2.24
Mitotic Spindle -0.48 -1.91 -5.20 -5.16 0.05 -0.07 -2.37 -2.12 -2.11 -0.11 -0.22 -2.17 -5.29 -5.28 -1.33
None 4.22 5.28 0.50 -1.85 -2.27 1.08 -1.71 3.09 2.98 3.74 4.66 4.35 -0.63 -2.21 -2.11
Nuclear Periphery -2.61 -3.73 -5.01 -2.27 3.31 -0.42 -2.70 -0.78 -0.24 2.53 -2.33 -4.31 -4.73 -3.14 3.53
Nuclear Periphery Foci -3.40 -3.54 -3.56 -3.27 2.34 0.14 -1.89 -2.00 -2.03 0.95 -1.47 -3.99 -3.58 -3.43 1.84
Nucleolus -1.66 -5.24 -6.95 -6.52 4.75 0.01 -6.77 -1.72 -1.54 6.71 -0.83 -8.42 -6.92 -6.67 7.64
Nucleus 0.90 -3.48 -6.60 -7.29 2.54 2.01 -6.79 0.46 -2.06 6.84 2.30 -7.35 -6.74 -7.89 6.00
Peroxisomes 1.00 -2.92 -2.22 -2.83 2.14 -0.91 -3.68 -1.83 0.27 3.34 -0.49 -4.65 -2.79 -1.79 3.24
Vacuole 5.82 4.28 -36.83 -41.18 -22.28 6.43 -8.61 -14.87 -17.38 -6.13 8.75 -3.70 -42.11 -49.24 -17.80
Vacuole Periphery -11.77 -0.19 44.53* 58.14* 14.47 -6.70 16.43 15.84 18.78 1.38 -13.67 9.44 57.98 74.69* 13.16
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; predicted to be palmitoylated
Localization
Cell Percentages vacuolar membrane (81%)
Cell Cycle Regulation No
Subcompartmental Group vac memb-2

YLR001C

YLR001C


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ylr001c-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available