Standard name
Human Ortholog
Description Methylthioadenosine phosphorylase (MTAP); catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Cytoplasm 0.99 1.0 0.9 0.85 0.86 0.8 0.7 0.69 0.58 0.6 0.51 0.51 0.88 0.87 0.9 0.73 0.74 0.87 0.94 0.94 0.82 0.87 0.82 0.79
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0.06 0 0 0 0 0.06 0 0.05 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.13 0.29 0.2 0.47 0.37 0.57 0.4 0 0 0 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0.05 0.18 0.18 0.15 0.15 0.14 0.1 0.12 0.07 0.15 0.12 0.19 0.09 0.33 0.2 0.1 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 1 0 0 2 0 0 0 0 0 0 0 1 0 0 0 0 0 0 2 2
Bud 0 0 0 0 0 3 0 2 10 3 6 7 1 0 0 0 0 0 2 0 1 0 2 2
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 1
Bud Site 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 2 0 4 1 0 1 2 1 0 2 4 3 5 2 0 0 0 0 0 0
Cytoplasm 303 38 114 188 250 209 285 231 164 153 136 109 189 296 370 119 75 75 296 57 125 163 280 219
Endoplasmic Reticulum 1 0 2 3 0 2 1 2 3 3 1 0 2 1 1 4 2 1 0 0 0 2 2 5
Endosome 0 0 6 6 8 2 4 6 0 3 0 2 2 9 17 10 4 3 0 0 9 1 16 9
Golgi 0 0 0 0 0 1 0 1 0 0 0 0 0 3 2 6 5 1 0 0 1 2 3 1
Mitochondria 1 0 1 0 1 35 119 67 133 95 150 86 0 0 5 0 3 2 0 0 3 1 3 2
Nucleus 1 0 4 5 2 6 14 11 12 6 11 11 2 3 1 4 0 1 8 1 2 7 10 9
Nuclear Periphery 0 0 0 0 0 0 0 1 0 0 0 1 0 0 2 0 0 0 0 0 0 0 1 1
Nucleolus 0 0 0 2 0 0 5 0 0 1 1 1 0 2 5 4 2 2 0 0 0 0 0 1
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 0 0 0 0 0
SpindlePole 0 0 0 1 2 0 0 3 1 0 0 1 2 0 5 1 4 0 0 0 1 0 6 5
Vac/Vac Membrane 1 0 6 39 53 39 60 48 28 31 18 31 25 64 36 54 20 9 0 1 3 2 6 8
Unique Cell Count 306 38 127 220 292 262 409 335 284 256 265 213 214 341 413 164 101 86 316 61 152 188 343 278
Labelled Cell Count 307 38 133 245 319 297 492 375 353 296 325 251 223 380 450 206 120 96 316 61 152 188 343 278


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.8 10.7 8.2 8.7 8.0 6.0 5.5 5.7 4.9 5.1 4.7 5.0 9.8 9.4 8.5 14.9 16.1 15.4 9.6 9.9 9.8
Std Deviation (1e-4) 1.3 2.0 1.5 1.4 1.5 1.5 1.3 1.3 1.1 1.2 1.4 1.3 1.6 1.6 1.3 3.7 3.1 3.8 1.7 1.9 1.7
Intensity Change (Log2) – – – 0.09 -0.02 -0.45 -0.56 -0.51 -0.75 -0.67 -0.81 -0.72 0.26 0.21 0.06 0.87 0.98 0.92 0.24 0.28 0.27

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP700051015WT3HU80HU120HU160051015WT3rpd3Δ_1rpd3Δ_2rpd3Δ_3051015WT1AF100AF140AF180051015
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -1.2 -1.2 -2.5 -4.5 -4.6 -6.4 -6.0 -7.4 -7.2 -0.4 -0.9 -0.1 -3.6 -3.1 -0.6
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 0 0 0 0 -0.3 0.5 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 4.0 6.7 5.2 0 7.7 0 8.1 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0.9 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 3.5 3.6 2.9 3.0 2.9 1.7 2.3 0.8 2.8 2.2 3.8 1.5 5.9 3.6 1.6

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.3174 5.5881 5.004 4.591 4.6581 4.9598 4.2369 5.4271 4.9186 3.5825 4.8257 4.9981 5.4415 6.215 6.0536 5.8532 4.1121 6.062
Actin 0.0127 0.0003 0.0036 0.0181 0.0021 0.0002 0.022 0.0008 0.0013 0.0024 0.0002 0.0124 0.0126 0.001 0.0052 0.0002 0.0318 0.0014
Bud 0.0008 0.0005 0.0011 0.0019 0.0002 0.0001 0.0045 0.0078 0.0069 0.0004 0.0001 0.0004 0.0007 0.0004 0.0003 0.0001 0.0017 0.0002
Bud Neck 0.002 0.0006 0.001 0.0008 0.0014 0.0017 0.0016 0.0006 0.0011 0.0015 0.0012 0.0035 0.0012 0.0005 0.0005 0.0006 0.0068 0.002
Bud Periphery 0.0008 0.0001 0.0004 0.0029 0.0002 0 0.0015 0.0033 0.0014 0.0002 0 0.0004 0.0007 0.0001 0.0003 0 0.002 0.0001
Bud Site 0.0011 0.0012 0.0017 0.0016 0.0004 0.0001 0.0064 0.0057 0.001 0.0005 0.0001 0.0007 0.002 0.0021 0.0007 0.0001 0.0023 0.0002
Cell Periphery 0.0001 0 0.0001 0 0 0 0.0002 0.0001 0.0001 0 0 0 0.0001 0 0.0001 0 0.0003 0
Cytoplasm 0.3514 0.4841 0.3845 0.219 0.3481 0.3396 0.4498 0.6184 0.4273 0.3818 0.5588 0.5504 0.4527 0.6525 0.4014 0.5197 0.2987 0.4289
Cytoplasmic Foci 0.0183 0.0018 0.0078 0.0141 0.0077 0.0018 0.0364 0.005 0.0123 0.0246 0.0075 0.0069 0.0136 0.0043 0.0059 0.0011 0.046 0.0047
Eisosomes 0.0002 0 0 0 0 0 0.0003 0 0 0 0 0.0001 0.0003 0 0.0001 0 0.0009 0
Endoplasmic Reticulum 0.0087 0.0028 0.0046 0.0021 0.0044 0.002 0.0051 0.0028 0.0042 0.0026 0.0022 0.0046 0.0053 0.0026 0.0021 0.0011 0.0203 0.0028
Endosome 0.0436 0.0031 0.0113 0.013 0.0221 0.0037 0.0357 0.0038 0.01 0.0206 0.0041 0.0094 0.0188 0.0034 0.0039 0.0008 0.078 0.0069
Golgi 0.0052 0.0001 0.0026 0.003 0.0033 0.0001 0.0072 0.0003 0.0007 0.0069 0.0002 0.0019 0.0038 0.0005 0.0014 0 0.0204 0.0011
Lipid Particles 0.0124 0 0.0027 0.0019 0.0145 0 0.0163 0.0001 0.0005 0.0737 0 0.001 0.0065 0.0002 0.0039 0 0.0633 0.0024
Mitochondria 0.0055 0.0005 0.0037 0.0038 0.0076 0.0004 0.0066 0.0074 0.0012 0.0021 0.0003 0.0133 0.0085 0.0093 0.012 0.0003 0.0339 0.0016
None 0.0137 0.0037 0.0077 0.0022 0.0103 0.0044 0.0341 0.0148 0.0143 0.0063 0.0092 0.0035 0.0141 0.0049 0.0091 0.0009 0.0133 0.0011
Nuclear Periphery 0.031 0.0197 0.0195 0.0138 0.0487 0.0159 0.032 0.0145 0.0272 0.015 0.0109 0.0204 0.0253 0.0137 0.0155 0.0114 0.0706 0.0187
Nucleolus 0.0012 0.0005 0.0011 0.0008 0.0016 0.0005 0.0013 0.0005 0.0005 0.0008 0.0003 0.0005 0.0015 0.0003 0.0003 0.0002 0.0023 0.0004
Nucleus 0.4558 0.4705 0.5268 0.6668 0.4673 0.6186 0.3107 0.2987 0.4777 0.4179 0.3973 0.3601 0.4094 0.296 0.5268 0.4606 0.2535 0.5149
Peroxisomes 0.0087 0.0001 0.0015 0.0178 0.0065 0.0001 0.0141 0.0002 0.001 0.0293 0.0001 0.0014 0.0087 0.0007 0.0054 0 0.0241 0.0017
Punctate Nuclear 0.0201 0.0073 0.0146 0.0041 0.045 0.0083 0.0095 0.0128 0.0079 0.0115 0.0067 0.0055 0.0069 0.0056 0.0035 0.0019 0.0148 0.0088
Vacuole 0.0049 0.0027 0.0029 0.0107 0.0043 0.002 0.0031 0.0019 0.0021 0.0015 0.0006 0.0026 0.0058 0.0015 0.0012 0.0008 0.0095 0.0016
Vacuole Periphery 0.0019 0.0005 0.0008 0.0016 0.0041 0.0004 0.0016 0.0004 0.0013 0.0006 0.0002 0.0008 0.0015 0.0004 0.0004 0.0002 0.0056 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 94.1267 60.311 56.3026 63.6434 65.605 47.853 53.1119 49.7875 45.5668 72.5471
Translational Efficiency 0.9182 1.3455 1.2034 0.9147 1.0918 1.4382 1.4176 1.0662 1.2503 1.1427

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1938 368 2671 1492 1877 1678 145 1352 3815 2046 2816 2844

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 957.56 996.44 1294.52 1413.20 965.87 1079.01 1456.30 1447.23 961.65 1064.16 1302.85 1429.38
Standard Deviation 143.62 198.53 193.49 232.85 147.60 176.64 196.56 243.17 145.65 183.53 196.92 238.42
Intensity Change Log 2 — 0.057420 0.434982 0.561531 — 0.159807 0.592407 0.583393 — 0.109743 0.516180 0.572551

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000204 0.001082 0.000224 0.001040 0.000245 0.000467 0.001130 0.009038 0.000224 0.000577 0.000270 0.004842
Bud Neck 0.003626 0.004767 0.002591 0.004490 0.002592 0.003981 0.004605 0.007673 0.003117 0.004122 0.002694 0.006003
Bud Site 0.004661 0.017547 0.002052 0.012587 0.003408 0.012561 0.008333 0.040394 0.004044 0.013457 0.002376 0.025806
Cell Periphery 0.000076 0.000140 0.000058 0.000176 0.000082 0.000092 0.000262 0.000128 0.000079 0.000101 0.000068 0.000153
Cytoplasm 0.672374 0.673369 0.487510 0.513769 0.680494 0.702634 0.403649 0.384217 0.676369 0.697370 0.483192 0.452182
Cytoplasmic Foci 0.108047 0.066585 0.001406 0.014197 0.051280 0.058524 0.012081 0.048007 0.080117 0.059974 0.001955 0.030270
Eisosomes 0.000026 0.000029 0.000004 0.000012 0.000017 0.000018 0.000033 0.000015 0.000022 0.000020 0.000006 0.000013
Endoplasmic Reticulum 0.002641 0.002539 0.000659 0.000847 0.002975 0.001620 0.003986 0.000446 0.002805 0.001785 0.000830 0.000656
Endosome 0.004642 0.009841 0.000193 0.007457 0.002401 0.005470 0.003462 0.014287 0.003540 0.006256 0.000362 0.010704
Golgi 0.002103 0.001772 0.000047 0.007226 0.000655 0.001827 0.000365 0.029410 0.001390 0.001817 0.000063 0.017772
Lipid Particles 0.002060 0.001836 0.000231 0.001379 0.001051 0.001014 0.002699 0.002315 0.001563 0.001162 0.000358 0.001824
Mitochondria 0.002156 0.000501 0.000753 0.004363 0.002268 0.001518 0.000513 0.004836 0.002211 0.001335 0.000741 0.004588
Mitotic Spindle 0.002060 0.006862 0.007599 0.147076 0.004230 0.011009 0.032134 0.301437 0.003127 0.010263 0.008862 0.220457
None 0.003294 0.008813 0.009072 0.006995 0.003629 0.004093 0.005150 0.005800 0.003459 0.004942 0.008870 0.006427
Nuclear Periphery 0.000353 0.000306 0.000915 0.000839 0.000462 0.000430 0.002094 0.000614 0.000406 0.000408 0.000975 0.000732
Nuclear Periphery Foci 0.002012 0.004980 0.000370 0.005107 0.002784 0.002778 0.006931 0.003573 0.002392 0.003174 0.000708 0.004378
Nucleolus 0.000493 0.001823 0.000120 0.000556 0.000401 0.000431 0.000264 0.000632 0.000448 0.000682 0.000128 0.000592
Nucleus 0.140238 0.126859 0.472008 0.221696 0.209543 0.130606 0.341236 0.101888 0.174336 0.129932 0.465274 0.164741
Peroxisomes 0.001245 0.003120 0.000020 0.000553 0.000634 0.001593 0.000293 0.004434 0.000944 0.001868 0.000034 0.002398
Vacuole 0.046685 0.065179 0.014093 0.045147 0.030397 0.058663 0.170522 0.035489 0.038671 0.059835 0.022147 0.040555
Vacuole Periphery 0.001004 0.002049 0.000075 0.004488 0.000454 0.000672 0.000258 0.005369 0.000734 0.000919 0.000085 0.004907

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.17 -0.90 -5.88 1.27 -4.63 -3.38 -8.22 -2.25 -1.94 -0.50 -5.11 -1.70 -3.00 -1.95 -2.71
Bud Neck -1.41 0.62 -7.23 -3.09 -7.86 -2.62 -5.81 -9.46 -7.81 -1.03 -2.55 -1.08 -11.81 -8.65 -10.26
Bud Site -5.42 4.59 -8.88 1.05 -10.74 -6.60 -6.73 -12.98 -7.48 -8.81 -7.99 2.75 -15.63 -5.59 -16.50
Cell Periphery -4.29 1.54 -7.80 -1.95 -8.19 -1.34 -9.40 -7.46 -5.00 7.11 -3.39 -1.07 -10.35 -6.12 -9.27
Cytoplasm 1.55 34.40 28.89 14.71 1.47 -0.16 25.00 31.50 29.92 -7.22 0.14 43.88 42.67 35.70 3.24
Cytoplasmic Foci 5.77 31.07 19.67 5.88 -11.62 -2.07 18.61 0.96 2.65 -12.80 6.49 37.59 15.43 7.53 -19.12
Eisosomes -1.41 15.16 9.03 4.57 -7.51 -1.73 -9.40 2.85 5.30 10.69 -0.35 12.58 8.39 7.22 -5.30
Endoplasmic Reticulum -0.14 6.77 7.63 4.48 2.92 3.53 -4.15 8.09 9.42 9.01 3.61 7.62 11.03 9.37 9.40
Endosome -2.41 11.02 3.18 3.45 -6.47 -5.30 -3.44 -3.75 0.25 -0.91 -4.42 12.17 -0.87 3.28 -9.10
Golgi 0.94 5.22 0.65 -0.19 -3.11 -2.42 2.33 -3.13 -2.43 -3.32 -0.57 6.35 -2.59 -2.21 -4.37
Lipid Particles 0.21 6.99 -6.34 -5.20 -14.43 -0.24 -8.04 -10.32 -10.22 0.21 2.06 7.04 -11.64 -13.77 -17.81
Mitochondria 3.03 2.23 1.15 -2.39 -1.23 1.00 1.94 1.12 0.21 -0.86 1.68 2.76 1.58 -0.21 -1.26
Mitotic Spindle -1.85 -5.58 -20.41 -19.05 -19.31 -3.03 -2.14 -26.06 -25.19 -20.85 -4.08 -5.12 -32.69 -30.92 -31.23
None -1.84 -17.21 -9.19 0.02 2.76 -0.38 -0.44 -6.65 -4.60 -3.59 -1.68 -18.68 -11.17 -4.14 3.34
Nuclear Periphery -0.36 -22.73 -18.41 -17.93 -4.28 -0.58 -10.40 -13.30 -14.15 7.39 -1.92 -24.50 -22.55 -21.74 -0.25
Nuclear Periphery Foci -3.86 9.43 -8.30 -2.63 -10.23 -0.75 -4.45 -5.19 -4.77 1.56 -3.51 7.64 -9.67 -6.83 -12.84
Nucleolus -2.39 4.15 -4.57 0.89 -7.88 -0.29 0.24 -3.92 -5.57 -6.30 -1.72 3.47 -5.96 -3.88 -11.35
Nucleus 0.51 -62.64 -11.54 -7.65 40.80 12.23 -6.44 13.21 2.01 10.19 7.94 -59.64 0.45 -6.62 54.86
Peroxisomes -2.41 7.42 4.26 3.38 -7.96 -3.43 2.68 -4.54 -1.83 -6.17 -3.49 8.50 -1.90 1.91 -8.38
Vacuole -5.11 4.88 -15.73 -5.51 -18.58 -11.98 -12.81 -16.80 -7.75 8.82 -11.55 -3.91 -23.03 -10.86 -17.90
Vacuole Periphery -1.26 4.70 0.01 1.17 -2.86 -1.38 1.55 -1.68 -1.23 -2.22 -0.62 5.58 -1.17 -0.78 -3.92
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Methylthioadenosine phosphorylase (MTAP); catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression
Localization
Cell Percentages cytoplasm (96%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Meu1

Meu1


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Meu1-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available