Standard name
Human Ortholog
Description Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0.06 0 – 0.07 0.05 0 0 0 0 0 0 0 0 0 0 0.05 0.05
Bud Neck 0 0 0 0 0 0 0.05 0.05 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0.05 0 0.05 0 0 0.07 – 0.11 0.09 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0 0 0 0.06 0.05 0 0 0 – 0 0 0 0 0.06 0.08 0.07 0.1 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0.13 0 0 0 0 0 0 0 – 0 0 0.12 0.23 0.21 0.13 0.14 0.11 0.05 0.12 0.1 0.12 0.14 0.13
Golgi 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.07 0 0 0 0 0.05 0.08 0 0.14 – 0.11 0.05 0 0 0 0.13 0 0.07 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.67 0.6 0.51 0.47 0.43 0.45 0.47 0.42 0.47 – 0.48 0.43 0.58 0.56 0.49 0.67 0.66 0.59 0.05 0.08 0 0 0 0
Peroxisomes 0.08 0.12 0 0 0 0.06 0 0 0 – 0 0 0.14 0.2 0.27 0.05 0 0.07 0 0 0 0.13 0.14 0.13
SpindlePole 0.57 0.62 0.89 0.83 0.77 0.71 0.73 0.72 0.63 – 0.7 0.75 0.59 0.57 0.5 0.38 0.48 0.48 0.74 0.63 0.74 0.55 0.49 0.5
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0.06 0.07 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 1 1 2 1 1 1 0 3 0 – 0 1 1 0 2 2 0 0 1 1 0 3 10 12
Bud 1 3 3 3 2 11 17 22 9 – 17 17 3 0 0 3 1 1 3 5 1 9 35 34
Bud Neck 1 9 9 1 5 8 18 18 12 – 10 15 7 6 3 2 5 2 0 8 3 4 18 21
Bud Site 4 9 10 10 5 14 16 6 20 – 28 31 13 4 9 3 1 9 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 7 4 7 7 15 14 14 11 3 – 4 5 16 18 35 24 21 27 0 0 0 0 0 3
Endoplasmic Reticulum 0 0 0 0 1 0 1 0 0 – 0 0 0 0 0 0 3 5 0 0 0 0 4 0
Endosome 7 52 6 4 10 9 4 12 2 – 0 3 72 93 121 40 45 31 8 54 25 31 96 80
Golgi 0 0 1 0 0 0 0 0 0 – 0 0 0 0 0 1 2 2 1 3 0 1 6 4
Mitochondria 12 14 4 3 4 16 29 12 41 – 28 17 20 4 4 39 11 20 1 6 4 4 13 12
Nucleus 2 4 7 6 8 8 14 9 8 – 5 18 8 8 6 3 5 1 2 2 2 1 1 0
Nuclear Periphery 0 0 0 0 0 2 0 0 0 – 1 0 0 0 1 0 0 1 0 0 0 0 1 0
Nucleolus 113 244 127 102 103 136 179 160 142 – 123 140 337 228 275 206 210 168 7 37 9 5 14 12
Peroxisomes 13 48 4 9 4 18 3 13 9 – 9 10 79 80 154 15 12 20 4 18 7 32 93 80
SpindlePole 96 250 221 180 185 213 277 276 190 – 179 245 343 232 284 118 154 136 124 276 197 139 334 315
Vac/Vac Membrane 0 4 0 0 3 0 0 3 2 – 0 0 7 11 14 17 21 16 0 1 1 2 6 3
Unique Cell Count 169 406 248 217 239 302 380 382 301 257 328 581 406 563 307 320 284 168 442 267 255 677 632
Labelled Cell Count 257 642 401 326 346 450 572 545 438 404 502 906 684 908 473 491 439 168 442 267 255 677 632


SpindlePole

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 8.8 9.0 7.4 6.8 8.0 6.6 6.1 6.9 5.7 – 5.5 5.9 8.2 8.5 8.5 16.2 15.2 15.0 7.5 7.4 7.6
Std Deviation (1e-4) 1.7 1.8 1.1 1.4 2.0 1.6 1.4 1.3 1.1 – 1.6 1.4 1.7 2.3 2.3 5.6 4.3 4.5 1.5 1.6 1.8
Intensity Change (Log2) – – – -0.12 0.11 -0.17 -0.27 -0.1 -0.38 – -0.42 -0.32 0.16 0.21 0.21 1.13 1.04 1.02 0.03 -0.0 0.04

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Bud 0 0 1.8 2.3 2.9 1.4 – 3.1 2.6 0 0 0 0 0 0
Bud Neck 0 -1.0 -0.7 0.7 0.7 0.2 – 0.2 0.6 0 -1.8 0 0 -1.6 -2.4
Bud Site 0.3 -1.2 0.3 0.1 -1.9 1.3 – 2.9 2.5 -1.4 -2.6 -2.1 -2.4 0 -0.5
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Cytoplasm 0.3 1.8 1.1 0.6 0 0 – -1.0 -1.1 -0.1 1.0 2.0 2.5 2.0 3.1
Endoplasmic Reticulum 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Endosome 0 1.1 0.4 0 0.5 0 – 0 0 4.5 7.1 6.9 4.5 4.8 3.8
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Mitochondria 0 0 2.3 3.3 1.2 5.1 – 4.3 2.3 1.4 0 0 4.9 1.3 3.0
Nucleus 0 0.3 -0.1 0.6 -0.4 -0.1 – -0.6 1.6 0 -0.7 0 0 -1.0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0
Nucleolus -0.9 -1.8 -1.4 -1.0 -2.3 -0.9 – -0.8 -2.0 1.8 1.2 -0.6 3.8 3.5 1.8
Peroxisomes 1.7 0 2.6 0 1.4 1.1 – 1.3 1.1 5.3 6.7 8.5 2.1 1.5 3.0
SpindlePole -1.9 -3.5 -5.3 -4.9 -5.1 -7.0 – -5.4 -4.4 -8.5 -8.6 -10.5 -12.2 -10.2 -10.1
Vacuole 0 0 0 0 0 0 – 0 0 0 0 0 3.8 4.1 3.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.2098 6.5261 6.3919 6.5112 4.9229 6.1168 6.838 6.9533 7.0456 6.9056 6.6293 6.5318 6.0149 5.8792 6.0341 6.5386 6.2193 5.9871
Actin 0.0158 0.0009 0.0001 0.0001 0.0001 0.0002 0.0009 0.0003 0.0045 0.0048 0.0014 0.0006 0.0071 0.0001 0.0063 0.0027 0.0033 0.0001
Bud 0.0002 0.0005 0.0001 0 0 0 0.0002 0.0002 0.0002 0.0015 0.0003 0 0.0001 0.0001 0.0001 0.0001 0.0001 0
Bud Neck 0.0076 0.0013 0.0003 0.0021 0.0002 0.0002 0.0005 0.0009 0.0003 0.0009 0.0002 0.0002 0.005 0.0005 0.0006 0.0009 0.0019 0.0017
Bud Periphery 0.0004 0.0006 0.0002 0 0 0 0.0002 0.0001 0.0003 0.0011 0.0005 0.0001 0.0002 0.0001 0.0002 0.0002 0.0003 0
Bud Site 0.0035 0.0155 0.001 0.0001 0.0001 0.0001 0.0023 0.0073 0.0012 0.0013 0.0025 0.0001 0.0014 0.0009 0.0005 0.0012 0.0004 0.0001
Cell Periphery 0.0006 0.0002 0 0 0 0 0 0 0 0.0002 0.0001 0 0.0001 0 0 0.0001 0.0001 0
Cytoplasm 0.0023 0.0018 0.0005 0.0001 0.0001 0 0.0016 0.0001 0.0002 0.0032 0.0001 0.0001 0.0017 0.0001 0.0001 0.0019 0.0002 0.0001
Cytoplasmic Foci 0.0891 0.01 0.0274 0.0252 0.0874 0.0206 0.068 0.0359 0.0116 0.0387 0.0565 0.0129 0.0375 0.0049 0.0065 0.0135 0.0376 0.0104
Eisosomes 0.0002 0.0001 0 0 0 0 0 0 0 0 0.0001 0 0.0001 0 0.0001 0.0001 0.0001 0
Endoplasmic Reticulum 0.0008 0.0006 0.0009 0 0 0 0.0011 0 0.0001 0.0002 0.0006 0.0001 0.0009 0 0.0002 0.0029 0.0005 0
Endosome 0.0095 0.0053 0.0032 0.0004 0.0028 0.0003 0.0151 0.0014 0.0043 0.0063 0.0025 0.0016 0.0026 0.0001 0.0033 0.0197 0.0018 0.0019
Golgi 0.0047 0.0006 0.0006 0.0008 0.0048 0.0009 0.0081 0.0012 0.0038 0.0014 0.0033 0.0024 0.0032 0.0003 0.0021 0.0032 0.0026 0.0009
Lipid Particles 0.0492 0.0055 0.0137 0.0089 0.2385 0.0177 0.0425 0.013 0.014 0.0346 0.092 0.0147 0.0306 0.0023 0.0079 0.0184 0.0557 0.01
Mitochondria 0.0008 0.0005 0.0006 0 0.0002 0 0.0022 0.0001 0.0086 0.0133 0.0077 0.0031 0.0024 0.0003 0.0007 0.0021 0.0096 0.0037
None 0.0061 0.0014 0.0002 0.0001 0.0001 0 0.0008 0.0001 0.0003 0.0005 0.0003 0.0001 0.0038 0.0001 0.0002 0.0061 0.0004 0
Nuclear Periphery 0.0013 0.0106 0.0048 0.0008 0.0031 0.0005 0.0023 0.0009 0.0005 0.006 0.0025 0.0007 0.0022 0.001 0.0016 0.0096 0.0134 0.0008
Nucleolus 0.0112 0.118 0.0735 0.0276 0.015 0.014 0.0489 0.0659 0.0966 0.0213 0.0116 0.0251 0.0482 0.0872 0.0857 0.0226 0.0161 0.0389
Nucleus 0.0014 0.1626 0.0228 0.0028 0.0008 0.0019 0.0084 0.0245 0.014 0.0128 0.0017 0.0033 0.0102 0.0613 0.0242 0.0122 0.0129 0.0091
Peroxisomes 0.0149 0.0006 0.0012 0.0011 0.0053 0.0187 0.0057 0.0076 0.0033 0.0052 0.0028 0.0013 0.0072 0.0008 0.0016 0.0037 0.0139 0.0013
Punctate Nuclear 0.7802 0.6588 0.8465 0.9299 0.6407 0.9249 0.7903 0.8405 0.8357 0.8445 0.8122 0.9335 0.8352 0.8398 0.8577 0.8754 0.8279 0.9205
Vacuole 0.0003 0.0034 0.0017 0 0.0003 0 0.0004 0.0001 0.0004 0.0014 0.0006 0.0001 0.0003 0.0001 0.0002 0.0021 0.0004 0.0002
Vacuole Periphery 0.0002 0.0013 0.0008 0 0.0002 0 0.0003 0 0.0002 0.0008 0.0004 0.0002 0.0002 0.0001 0.0002 0.0011 0.0008 0.0001

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.9617 35.8749 10.7032 13.5855 36.7443 27.2907 31.2248 22.3366 17.2587 28.4844
Translational Efficiency 1.6346 1.2993 1.3948 1.1032 0.8986 1.0965 1.0841 0.95 1.0207 1.0676

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
2334 1394 1263 1459 1268 635 182 1392 3602 2029 1445 2851

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 769.39 1000.34 1252.98 1219.23 848.65 944.59 1225.09 1089.14 797.29 982.89 1249.47 1155.71
Standard Deviation 107.46 157.33 198.99 208.86 129.59 389.08 155.34 210.67 121.77 255.05 194.26 219.59
Intensity Change Log 2 — 0.378703 0.703576 0.664183 — 0.154519 0.529646 0.359948 — 0.265471 0.614970 0.512627

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000369 0.000741 0.000204 0.000751 0.000781 0.000733 0.000417 0.000992 0.000514 0.000739 0.000231 0.000869
Bud Neck 0.002038 0.002565 0.002502 0.005260 0.003257 0.003251 0.001882 0.003342 0.002467 0.002780 0.002424 0.004323
Bud Site 0.001943 0.002673 0.002541 0.011240 0.003838 0.003867 0.001690 0.004128 0.002610 0.003047 0.002434 0.007768
Cell Periphery 0.000124 0.000080 0.000040 0.000070 0.000198 0.000165 0.000029 0.000066 0.000150 0.000106 0.000039 0.000068
Cytoplasm 0.002016 0.001742 0.002595 0.004933 0.006500 0.003223 0.000455 0.001642 0.003594 0.002205 0.002326 0.003326
Cytoplasmic Foci 0.020586 0.013882 0.005381 0.014260 0.033750 0.018045 0.002271 0.011937 0.025220 0.015185 0.004989 0.013126
Eisosomes 0.000183 0.000112 0.000009 0.000019 0.000198 0.000118 0.000017 0.000044 0.000188 0.000114 0.000010 0.000031
Endoplasmic Reticulum 0.001705 0.001664 0.000384 0.000517 0.002754 0.002042 0.000833 0.000490 0.002074 0.001782 0.000441 0.000504
Endosome 0.002692 0.003261 0.000704 0.002408 0.004850 0.003585 0.000477 0.002127 0.003452 0.003362 0.000675 0.002271
Golgi 0.004979 0.003222 0.000428 0.001800 0.007536 0.006015 0.000467 0.001645 0.005879 0.004096 0.000433 0.001724
Lipid Particles 0.038917 0.011017 0.001264 0.001184 0.030314 0.014699 0.001006 0.002455 0.035888 0.012169 0.001231 0.001805
Mitochondria 0.001129 0.000635 0.000196 0.001848 0.001430 0.002077 0.000235 0.001419 0.001235 0.001086 0.000201 0.001639
Mitotic Spindle 0.780547 0.818957 0.959280 0.893975 0.666250 0.790729 0.936720 0.862545 0.740311 0.810123 0.956439 0.878629
None 0.002019 0.000547 0.000147 0.000434 0.002880 0.000944 0.000118 0.001218 0.002322 0.000671 0.000143 0.000817
Nuclear Periphery 0.000660 0.000607 0.000378 0.000602 0.000856 0.000612 0.000305 0.000523 0.000729 0.000608 0.000368 0.000563
Nuclear Periphery Foci 0.054225 0.047276 0.002707 0.003488 0.085130 0.052790 0.003431 0.008319 0.065104 0.049001 0.002798 0.005847
Nucleolus 0.043730 0.049054 0.010795 0.027141 0.079912 0.050893 0.022872 0.061624 0.056467 0.049630 0.012316 0.043977
Nucleus 0.010014 0.013607 0.005516 0.014451 0.027573 0.016800 0.019214 0.014555 0.016195 0.014606 0.007241 0.014502
Peroxisomes 0.031323 0.026640 0.003248 0.008004 0.040122 0.026234 0.005794 0.019509 0.034420 0.026513 0.003568 0.013621
Vacuole 0.000706 0.001465 0.001583 0.004871 0.001585 0.001650 0.001674 0.001182 0.001016 0.001523 0.001594 0.003070
Vacuole Periphery 0.000095 0.000253 0.000099 0.002745 0.000285 0.001529 0.000093 0.000240 0.000162 0.000653 0.000098 0.001522

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.40 -0.52 -2.52 -0.28 -1.81 0.33 -0.15 -0.82 -0.92 -0.58 -1.17 0.24 -2.36 -0.76 -2.16
Bud Neck -2.61 -5.01 -9.18 -7.99 -4.67 0.00 -0.56 -3.23 -2.61 -1.41 -1.87 -4.45 -9.75 -8.24 -3.79
Bud Site -2.79 -5.05 -9.07 -7.93 -6.36 0.17 0.63 -2.71 -2.28 -2.59 -1.84 -3.93 -9.64 -8.20 -6.00
Cell Periphery 3.28 4.57 2.69 -0.41 -2.34 1.28 7.60 6.69 2.55 -1.96 3.24 7.57 6.34 1.99 -2.48
Cytoplasm 0.50 -1.76 -4.17 -4.27 -2.23 2.10 4.69 3.39 0.92 -2.62 2.15 0.22 -1.36 -3.18 -1.24
Cytoplasmic Foci 3.09 8.19 1.47 -1.21 -5.46 4.46 11.45 6.73 1.56 -6.05 5.38 12.23 5.50 0.20 -6.46
Eisosomes 5.76 17.51 16.79 14.05 -2.56 4.02 13.19 11.37 6.46 -2.43 7.10 22.55 19.36 13.57 -5.01
Endoplasmic Reticulum -0.32 7.54 5.95 5.54 -0.09 2.55 1.53 13.46 7.90 1.73 1.48 8.67 12.21 9.13 0.62
Endosome -0.72 3.68 0.56 1.12 -3.14 1.75 6.26 3.96 2.22 -1.64 0.24 6.85 2.89 2.00 -3.15
Golgi 4.55 15.91 8.10 4.62 -2.66 1.83 13.31 10.58 6.27 -2.76 4.67 20.66 13.26 7.93 -4.01
Lipid Particles 10.21 14.96 15.10 7.38 0.27 4.15 10.53 10.05 6.38 -1.69 10.95 18.11 17.93 9.41 -1.14
Mitochondria 1.62 3.29 -1.49 -2.40 -3.08 -0.56 2.89 -0.15 0.42 -2.12 0.63 4.49 -1.28 -1.60 -3.81
Mitotic Spindle -2.87 -20.20 -9.46 -5.71 8.93 -7.04 -11.81 -14.94 -4.93 2.83 -6.88 -26.86 -16.19 -7.25 11.27
None 3.98 4.77 3.57 -1.06 -3.55 4.99 7.51 3.13 -0.28 -2.00 6.00 7.63 4.14 -0.86 -2.67
Nuclear Periphery 1.12 1.92 -1.93 -2.68 -3.20 3.40 3.52 2.74 -0.45 -1.57 2.86 3.50 0.11 -2.29 -3.04
Nuclear Periphery Foci 1.51 18.90 19.11 13.32 0.29 3.80 16.72 16.81 9.48 -1.27 3.76 25.57 24.88 15.97 -1.88
Nucleolus -2.08 9.69 1.59 3.27 -6.49 3.78 4.75 1.86 -2.22 -3.61 1.05 13.33 1.15 0.04 -11.01
Nucleus -3.39 -0.86 -5.70 -3.20 -4.41 3.06 -0.51 2.90 -0.62 1.39 -0.15 0.86 -3.42 -2.98 -3.27
Peroxisomes 0.97 16.14 12.49 9.88 -3.19 3.41 10.75 6.91 2.50 -5.44 2.82 20.62 12.75 8.33 -8.88
Vacuole -4.76 -3.87 -5.01 -3.67 -1.42 -0.42 -1.42 -0.96 -0.47 1.33 -4.15 -3.74 -5.33 -3.56 0.32
Vacuole Periphery -3.09 -4.09 -2.89 -2.66 -2.79 -0.95 1.57 -0.08 0.94 -1.37 -1.26 -0.61 -2.95 -1.39 -2.91
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p
Localization
Cell Percentages spindle pole (26%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Stu2

Stu2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Stu2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available