Standard name
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.17 0.21 0.13 0 0 0 0 0 0
Bud 0 0 0 0 0 0 – 0 0 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.07 0.17 0.13 0.15 0 0 0 0 0 0
Cytoplasm 0.6 0.4 0.5 0.44 0.62 0.44 – 0.39 0.36 0.41 0.43 0.4 0.54 0.64 0.72 0.27 0.27 0.26 0.19 0.09 0.1 0.12 0.17 0.19
Endoplasmic Reticulum 0.21 0.56 0.26 0.34 0.19 0.25 – 0.21 0.22 0.17 0.17 0.14 0.45 0.37 0.24 0 0 0 0.61 0.7 0.65 0.6 0.55 0.51
Endosome 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0.19 0.13 0.17 0 0 0 0 0 0
Mitochondria 0.06 0 0.27 0.46 0.18 0.48 – 0.44 0.55 0.47 0.52 0.53 0 0 0 0.06 0.07 0.05 0.06 0.05 0.12 0.12 0.11 0.06
Nucleus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 – 0 0.05 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0.18 0.09 0.07 0 0.1 0.05 – 0.08 0.07 0.11 0.05 0.06 0 0 0 0.29 0.31 0.38 0 0 0 0 0.06 0.08
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 5 6 1 0 2 0 – 2 2 2 3 3 0 1 1 45 38 31 8 4 8 4 8 9
Bud 3 3 5 2 3 6 – 10 11 9 16 16 0 0 0 2 2 3 13 3 0 6 4 11
Bud Neck 0 0 1 0 1 0 – 0 0 0 0 0 1 0 0 0 0 0 8 2 1 1 1 3
Bud Site 1 0 2 0 0 0 – 2 0 1 0 2 0 0 0 0 0 1 – – – – – –
Cell Periphery 0 4 1 5 6 8 – 5 6 9 6 18 7 6 17 45 23 36 4 0 2 1 2 1
Cytoplasm 263 87 96 54 121 117 – 144 125 163 144 178 96 98 164 69 48 62 110 23 22 24 49 53
Endoplasmic Reticulum 91 122 49 42 38 65 – 77 76 67 57 60 80 57 54 3 8 5 349 180 148 121 161 142
Endosome 9 3 1 0 8 0 – 4 3 7 2 5 1 0 1 10 1 3 6 5 1 1 3 7
Golgi 1 0 0 0 0 0 – 0 0 0 0 0 0 0 1 48 23 40 5 2 0 2 2 4
Mitochondria 24 1 51 56 35 126 – 161 194 186 175 236 2 3 2 15 13 12 34 13 27 23 33 17
Nucleus 2 1 1 0 0 0 – 6 1 2 1 3 0 1 0 2 4 5 1 0 0 0 0 0
Nuclear Periphery 1 1 1 1 0 3 – 10 19 11 2 8 1 0 0 0 1 2 3 3 4 2 2 0
Nucleolus 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 – 1 1 1 1 1 0 0 0 2 1 2 4 0 1 0 2 1
Vac/Vac Membrane 79 20 13 0 20 14 – 29 26 43 17 27 2 1 5 75 56 88 19 8 4 7 17 21
Unique Cell Count 435 216 192 123 196 265 369 350 398 337 444 177 154 227 258 179 234 576 256 229 202 295 281
Labelled Cell Count 479 248 222 160 234 339 452 464 501 425 557 190 167 245 318 219 291 576 256 229 202 295 281


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.6 7.2 4.5 4.9 5.8 4.7 – 5.0 4.6 4.9 4.8 4.8 6.4 6.8 6.4 11.6 11.1 11.0 6.5 6.6 7.0
Std Deviation (1e-4) 1.2 1.6 1.1 1.1 2.1 1.3 – 1.7 1.5 1.4 1.7 1.6 1.4 1.6 1.5 2.7 2.5 2.4 1.7 1.8 1.9
Intensity Change (Log2) – – – 0.11 0.37 0.07 – 0.15 0.02 0.12 0.11 0.08 0.51 0.61 0.52 1.37 1.3 1.3 0.54 0.55 0.65


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 – 0 0 0 0 0 0 0 0 5.9 6.5 5.0
Bud 0 0 0 – 0.1 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 – 0 0 0 0 0 0 0 3.5 5.9 4.8 5.4
Cytoplasm -1.1 2.3 -1.2 – -2.5 -3.2 -2.1 -1.6 -2.3 0.8 2.5 4.7 -5.1 -4.6 -5.0
Endoplasmic Reticulum 0 -1.4 0 – -1.3 0 -2.5 0 0 4.0 2.3 -0.4 -8.0 -5.6 -7.2
Endosome 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 – 0 0 0 0 0 0 0 0 6.3 5.1 6.0
Mitochondria 0 -2.1 0 – 4.0 0 4.7 0 0 -7.0 -6.3 -7.9 -6.2 -4.9 -6.2
Nucleus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0
Vacuole -2.9 1.2 -0.7 – 0.5 0.3 1.6 -0.8 -0.3 -2.7 -2.9 -2.3 5.9 6.1 7.4

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.2053 2.6698 2.2548 2.4825 2.0476 2.5568 2.5992 2.235 2.6879 1.7503 2.3712 1.7933 3.5466 3.5868 3.4065 3.353 3.0762 3.3758
Actin 0.0091 0.0024 0.0138 0.0018 0.011 0.0009 0.0338 0.0035 0.0101 0.0024 0.0155 0.0013 0.0272 0.0005 0.0098 0.0011 0.0009 0.0015
Bud 0.0002 0.0002 0.0008 0.0001 0.0003 0 0.0014 0.0022 0.0012 0.0003 0.0363 0.0001 0.0002 0.0001 0.0001 0.0014 0 0
Bud Neck 0.0002 0.0008 0.0015 0.0003 0.0006 0.0005 0.003 0.0003 0.0009 0.0167 0.0028 0.0076 0.0011 0.0002 0.0008 0.0006 0.0005 0.0018
Bud Periphery 0.0003 0.0011 0.0014 0.0002 0.0008 0.0001 0.0012 0.0006 0.0013 0.0004 0.0189 0.0002 0.0004 0.0001 0.0003 0.0007 0 0.0001
Bud Site 0.0006 0.0044 0.0109 0.0001 0.0011 0.0001 0.0079 0.009 0.0152 0.0051 0.0045 0.0001 0.0009 0.0105 0.0008 0.0003 0 0.0001
Cell Periphery 0.0008 0.0024 0.0014 0.0008 0.0003 0.0004 0.0012 0.0023 0.002 0.0004 0.0012 0.0006 0.001 0.0027 0.0019 0.0018 0.0003 0.0004
Cytoplasm 0.1307 0.2514 0.1685 0.1097 0.0965 0.1912 0.1434 0.2406 0.1867 0.1742 0.1835 0.2486 0.14 0.2631 0.2546 0.2175 0.2016 0.2488
Cytoplasmic Foci 0.0128 0.006 0.0156 0.0169 0.0137 0.0056 0.0225 0.01 0.0303 0.0111 0.0205 0.0067 0.0056 0.0052 0.0136 0.0055 0.0031 0.0083
Eisosomes 0.0002 0.0002 0.0002 0.0001 0.001 0 0.0009 0.0001 0.0005 0.0001 0.0005 0 0.0006 0.0001 0.0002 0.0001 0.0001 0
Endoplasmic Reticulum 0.6161 0.5797 0.6313 0.6916 0.5517 0.6614 0.5166 0.5562 0.5768 0.6566 0.3115 0.6391 0.661 0.5624 0.5636 0.6368 0.6387 0.6083
Endosome 0.0348 0.0167 0.0218 0.0262 0.0274 0.0167 0.0483 0.0251 0.0223 0.0213 0.0659 0.0108 0.0195 0.0152 0.0214 0.0126 0.0114 0.0155
Golgi 0.0041 0.0012 0.0049 0.0078 0.0084 0.0014 0.0096 0.0031 0.0052 0.0049 0.0218 0.0005 0.0065 0.0008 0.0034 0.0012 0.0016 0.0007
Lipid Particles 0.0218 0.0058 0.016 0.0632 0.0192 0.0063 0.032 0.0104 0.0168 0.0074 0.0044 0.0032 0.0147 0.0074 0.0086 0.0084 0.0065 0.0044
Mitochondria 0.0085 0.0098 0.0058 0.0343 0.0436 0.0019 0.0123 0.008 0.0162 0.0011 0.0189 0.0005 0.0028 0.0003 0.0011 0.001 0.0003 0.0006
None 0.093 0.0884 0.0674 0.0195 0.1188 0.0771 0.078 0.0816 0.0555 0.0628 0.1218 0.0466 0.0708 0.0813 0.0928 0.0607 0.1113 0.0808
Nuclear Periphery 0.0359 0.0154 0.0193 0.0144 0.0482 0.0249 0.0392 0.0281 0.026 0.0169 0.0541 0.0196 0.0285 0.0341 0.0107 0.0221 0.0174 0.0156
Nucleolus 0.0003 0.0002 0.0009 0.0001 0.0022 0.0001 0.0076 0.0005 0.0015 0.0005 0.0025 0.0002 0.0003 0.0001 0.0001 0.001 0.0001 0.0002
Nucleus 0.0073 0.004 0.0065 0.0014 0.0047 0.0034 0.012 0.0071 0.0038 0.007 0.0809 0.0042 0.005 0.0046 0.003 0.0171 0.0023 0.0042
Peroxisomes 0.0095 0.0001 0.0024 0.0044 0.0323 0.0016 0.0075 0.0004 0.013 0.0016 0.0032 0.0001 0.0052 0.0001 0.0049 0.0001 0.0001 0.0001
Punctate Nuclear 0.004 0.0017 0.0034 0.0006 0.0096 0.0014 0.01 0.002 0.0055 0.004 0.0055 0.0035 0.002 0.0016 0.0015 0.0024 0.0006 0.0035
Vacuole 0.0072 0.0071 0.0053 0.0054 0.0055 0.0041 0.0078 0.0082 0.0072 0.0047 0.0171 0.0059 0.0053 0.0084 0.0063 0.0061 0.0029 0.0044
Vacuole Periphery 0.0025 0.0009 0.001 0.0012 0.0028 0.0009 0.0037 0.0009 0.002 0.0007 0.0086 0.0008 0.0012 0.001 0.0005 0.0012 0.0005 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 69.2466 38.562 18.0724 24.2729 36.7956 27.2295 38.477 24.9306 27.8346 59.8695
Translational Efficiency 1.3555 1.7145 1.6216 1.4436 1.7225 3.8556 1.6531 1.7187 1.5816 1.454

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1794 1195 525 1015 1545 2101 313 1227 3339 3296 838 2242

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 710.24 806.76 1152.04 1141.96 673.59 811.58 1099.49 1121.71 693.28 809.83 1132.41 1130.88
Standard Deviation 106.42 114.32 181.30 212.71 120.69 111.31 160.65 196.70 114.71 112.43 175.72 204.36
Intensity Change Log 2 — 0.183833 0.697812 0.685134 — 0.268863 0.706892 0.735757 — 0.225848 0.702239 0.709997

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000186 0.000565 0.000674 0.007059 0.000202 0.000293 0.000893 0.004098 0.000194 0.000391 0.000756 0.005439
Bud Neck 0.004381 0.008229 0.001964 0.008535 0.006361 0.011817 0.002086 0.005905 0.005297 0.010516 0.002010 0.007096
Bud Site 0.002518 0.006031 0.004118 0.030057 0.002518 0.009690 0.004478 0.024863 0.002518 0.008363 0.004253 0.027215
Cell Periphery 0.000484 0.000395 0.000604 0.002667 0.000377 0.000421 0.000992 0.004053 0.000434 0.000412 0.000749 0.003426
Cytoplasm 0.373676* 0.306554* 0.103309* 0.097524 0.281026* 0.326951* 0.080271 0.101213* 0.330806* 0.319556* 0.094704 0.099543
Cytoplasmic Foci 0.131203 0.176405 0.009608 0.018127 0.144525 0.141561 0.018151 0.015683 0.137367 0.154194 0.012799 0.016790
Eisosomes 0.000273 0.000361 0.000068 0.000477 0.000405 0.000395 0.000318 0.000592 0.000334 0.000383 0.000161 0.000540
Endoplasmic Reticulum 0.201375* 0.225910* 0.595926* 0.583866* 0.232163* 0.194626* 0.624474* 0.672170* 0.215621* 0.205968* 0.606589* 0.632193*
Endosome 0.012759 0.021532 0.009268 0.017131 0.016046 0.023216 0.011752 0.016179 0.014280 0.022606 0.010196 0.016610
Golgi 0.006230 0.008776 0.000455 0.006115 0.007523 0.008029 0.000916 0.005349 0.006828 0.008300 0.000628 0.005696
Lipid Particles 0.078412 0.067069 0.007149 0.029869 0.098563 0.078580 0.017279 0.029947 0.087736 0.074407 0.010933 0.029912
Mitochondria 0.006135 0.007890 0.000438 0.003274 0.006863 0.011452 0.000402 0.003202 0.006472 0.010160 0.000425 0.003235
Mitotic Spindle 0.000626 0.003901 0.000366 0.010485 0.000373 0.004732 0.000150 0.005096 0.000509 0.004431 0.000285 0.007535
None 0.008928 0.003553 0.000431 0.001401 0.012256 0.003901 0.000217 0.001473 0.010468 0.003775 0.000351 0.001441
Nuclear Periphery 0.012668 0.009157 0.057858 0.006591 0.021557 0.014362 0.045580 0.003414 0.016781 0.012475 0.053272 0.004852
Nuclear Periphery Foci 0.007317 0.009211 0.086853 0.056338 0.012765 0.006547 0.077776 0.027676 0.009838 0.007513 0.083463 0.040652
Nucleolus 0.001313 0.001188 0.000176 0.000148 0.002253 0.001436 0.000188 0.000185 0.001748 0.001346 0.000180 0.000168
Nucleus 0.106742 0.067628 0.067402 0.021939 0.099598 0.081439 0.030032 0.018948 0.103437 0.076432 0.053444 0.020302
Peroxisomes 0.002534 0.006821 0.000163 0.000844 0.004389 0.005534 0.000505 0.001041 0.003392 0.006001 0.000291 0.000952
Vacuole 0.040465 0.065926 0.052818 0.095483 0.048040 0.071480 0.083196 0.056890 0.043970 0.069466 0.064165 0.074362
Vacuole Periphery 0.001777 0.002896 0.000349 0.002069 0.002197 0.003538 0.000346 0.002022 0.001971 0.003305 0.000348 0.002043

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -3.21 -2.61 -5.35 -5.05 -4.89 -1.77 -2.13 -7.48 -7.30 -5.38 -3.54 -3.36 -8.17 -7.87 -7.05
Bud Neck -3.43 4.02 -3.71 -0.68 -5.61 -4.78 4.46 -0.35 4.39 -4.74 -6.54 6.17 -3.21 2.72 -7.62
Bud Site -3.64 -1.71 -8.95 -7.76 -7.95 -5.33 -1.59 -8.98 -5.75 -7.34 -6.31 -2.32 -12.66 -9.31 -10.85
Cell Periphery 1.58 -1.03 -4.01 -4.20 -3.66 -1.12 -1.67 -6.67 -6.60 -4.54 0.66 -2.03 -7.68 -7.76 -6.29
Cytoplasm 6.97 27.35 32.57 21.65 0.01 -5.39 18.50 20.54 27.99 -2.73 1.75 31.90 37.76 35.74 -1.59
Cytoplasmic Foci -6.82 31.65 28.81 27.18 -4.46 0.51 24.54 28.67 31.83 1.15 -4.09 40.37 40.73 41.72 -2.26
Eisosomes -1.84 9.13 -2.16 -1.06 -4.46 0.15 0.52 -1.94 -1.81 -1.48 -1.09 2.72 -3.04 -2.00 -4.24
Endoplasmic Reticulum -1.99 -22.16 -22.41 -19.06 2.57 3.53 -16.89 -29.02 -34.14* -1.17 1.31 -27.67 -36.94 -37.94 0.26
Endosome -5.50 3.35 -3.01 2.42 -5.53 -5.42 2.79 0.03 4.29 -2.16 -8.20 4.79 -2.11 4.96 -5.59
Golgi -2.96 10.85 0.61 2.46 -4.33 -0.64 11.42 2.82 3.34 -5.92 -2.53 15.82 2.14 3.92 -7.12
Lipid Particles 2.89 24.43 13.37 10.04 -10.26 4.51 19.77 15.88 13.20 -4.21 4.49 31.67 20.57 16.72 -10.53
Mitochondria -1.38 6.81 2.38 3.50 -2.48 -4.07 9.72 3.33 6.42 -2.86 -4.25 11.13 3.93 7.37 -3.78
Mitotic Spindle -2.32 0.71 -5.13 -3.11 -5.24 -4.07 0.88 -4.11 -0.56 -4.33 -4.62 0.92 -6.55 -2.74 -6.72
None 4.00 7.48 5.43 2.05 -1.00 4.80 7.29 6.26 3.17 -2.90 6.24 10.32 8.40 3.65 -2.35
Nuclear Periphery 2.32 -8.79 4.45 2.01 10.14 3.59 -3.86 10.33 8.99 7.17 3.41 -9.16 10.96 8.28 12.58
Nuclear Periphery Foci -1.68 -14.35 -13.07 -12.25 4.56 5.03 -10.60 -6.62 -9.82 7.62 2.90 -17.66 -14.57 -15.70 9.10
Nucleolus 0.28 8.75 8.65 3.27 0.10 2.43 6.96 6.92 6.81 -0.15 1.78 10.09 9.99 7.21 -0.13
Nucleus 9.60 4.83 23.13 11.99 6.97 4.40 12.53 18.92 19.46 1.66 9.39 9.43 29.90 22.88 7.12
Peroxisomes -5.11 12.76 8.12 7.25 -6.19 -1.86 9.51 7.36 8.56 -2.20 -5.55 14.61 9.94 11.39 -4.77
Vacuole -7.24 -4.02 -12.94 -8.73 -8.26 -7.36 -4.91 -5.69 -0.96 1.85 -10.99 -6.16 -13.61 -7.21 -4.32
Vacuole Periphery -3.87 8.10 -0.24 2.05 -3.56 -4.40 12.07 0.62 3.16 -3.53 -6.01 13.67 0.22 3.86 -4.98
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene
Localization
Cell Percentages ER (71%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Ema19

Ema19


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ema19-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available