Standard name
Human Ortholog
Description Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0.05 0 0 0 0 0 0.05 0 0.06 0.06 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0 0.07 0 0 0.05 0 0 0 0 0 0 0 0.06 0.12 0.12 0.07 0.12 0.08 0 0 0 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 0 0 0 0.07 0.05 0.07 0 0 0 0 0 0 0 0.08 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0.05 0.26 0.21 0.15 0.37 0.24 0.26 0.44 0.31 0.44 0.38 0 0 0 0.1 0.08 0.07 0 0 0 0 0 0
Nucleus 0.31 0.19 0.27 0.16 0.23 0.13 0.11 0.15 0.13 0.12 0.1 0.13 0.17 0.08 0.14 0.14 0.15 0.16 0.23 0.12 0.13 0.06 0.08 0.07
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.82 0.81 0.82 0.83 0.7 0.74 0.7 0.63 0.65 0.63 0.59 0.64 0.81 0.83 0.78 0.79 0.75 0.76 0.65 0.68 0.62 0.71 0.61 0.6
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.14 0.1 0.15 0.16 0.2 0.32 0.37 0.34 0.34 0.4 0.36 0.36 0.18 0.23 0.2 0.13 0.12 0.13 0.06 0.08 0.17 0.14 0.19 0.19
Vac/Vac Membrane 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0
Bud 2 0 2 3 1 2 12 10 16 14 22 18 1 0 0 0 0 0 4 2 1 2 3 2
Bud Neck 7 0 4 4 3 1 8 16 3 10 7 4 5 5 5 1 1 1 2 1 0 1 2 5
Bud Site 1 1 10 8 4 18 22 14 30 31 35 45 1 1 0 0 2 1 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0
Cytoplasm 3 12 4 12 17 9 17 26 6 19 10 12 13 33 37 16 22 15 0 5 1 0 0 0
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 3 1 0 0 0 0 1 0
Endosome 3 2 1 1 26 23 44 32 12 29 6 21 2 11 24 7 3 5 5 3 5 1 8 13
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 2 1
Mitochondria 18 9 57 63 55 156 157 186 248 235 253 274 9 4 1 23 15 13 0 1 2 0 0 1
Nucleus 133 32 60 47 83 54 73 108 72 90 57 93 37 22 42 34 27 31 107 19 29 6 20 22
Nuclear Periphery 0 4 1 0 3 1 1 1 4 1 1 2 0 0 0 1 1 1 0 0 1 0 0 1
Nucleolus 355 137 180 248 255 315 458 450 369 474 337 465 172 223 242 186 135 146 298 109 137 83 155 183
Peroxisomes 0 0 0 0 1 6 10 11 7 4 4 8 0 0 3 0 1 0 0 0 0 0 1 0
SpindlePole 60 17 32 47 74 134 241 243 194 296 206 262 39 62 63 30 22 25 28 12 36 16 48 57
Vac/Vac Membrane 2 4 0 0 4 0 6 10 2 0 0 1 1 1 3 4 5 7 7 3 1 1 4 8
Unique Cell Count 435 169 220 298 365 425 656 717 565 747 569 724 212 270 310 236 179 193 460 162 220 117 253 305
Labelled Cell Count 584 218 351 433 526 719 1049 1108 963 1203 938 1205 281 362 420 306 238 247 460 162 220 117 253 305


Nucleolus, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.7 8.9 5.6 6.4 5.9 4.5 4.4 4.4 3.7 4.0 3.7 3.8 8.2 8.0 7.5 13.7 14.5 13.1 8.2 9.7 9.3
Std Deviation (1e-4) 1.5 2.1 1.4 1.7 1.4 1.1 1.3 1.3 0.9 1.1 1.1 0.9 2.0 2.6 2.0 5.8 5.7 4.6 2.0 2.3 2.3
Intensity Change (Log2) – – – 0.2 0.08 -0.32 -0.34 -0.33 -0.61 -0.46 -0.57 -0.54 0.55 0.52 0.42 1.3 1.38 1.23 0.55 0.79 0.74

WT3RAP60RAP140RAP220RAP300RAP380RAP460RAP540RAP620RAP70005101520WT3HU80HU120HU16005101520WT3rpd3Δ_1rpd3Δ_2rpd3Δ_305101520WT1AF100AF140AF18005101520
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site -1.1 -2.6 0 0 0 0 0 0 0 -2.7 0 0 0 -2.0 -2.5
Cell Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.4 1.8 0 0.6 1.3 0 0.6 0 0 2.3 4.3 4.3 2.6 4.2 2.9
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 3.7 0 0 0 0 0 0 0 0 2.6 3.9 0 0 0
Golgi 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria -1.3 -3.2 0 0 0 0 0 0 0 -6.3 -8.1 -9.3 -4.5 -4.5 -5.2
Nucleus -3.2 -1.2 -4.6 -5.8 -4.1 -4.9 -5.5 -6.1 -5.1 -2.4 -5.6 -3.9 -3.4 -2.9 -2.7
Nuclear Periphery 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0.4 -3.2 0 0 0 0 0 0 0 -0.2 0.2 -1.1 -0.8 -1.6 -1.5
Peroxisomes 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0.4 1.7 0 0 0 0 0 0 0 1.1 2.4 1.7 -0.6 -0.7 -0.5
Vacuole 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 2.6142 3.5413 2.9284 2.6932 2.0559 2.7984 2.9878 3.4876 3.2067 2.7708 2.7499 2.7649 4.7713 5.1772 4.6414 4.7902 4.6341 4.6184
Actin 0.0148 0 0.0101 0 0.0035 0 0.015 0.0001 0.0063 0.0022 0.006 0.0026 0.001 0 0 0 0 0
Bud 0.0002 0.0001 0.0001 0.0001 0.0004 0 0.0006 0.0001 0 0.0001 0.0001 0.0001 0 0 0 0 0 0
Bud Neck 0.0012 0.0046 0.0006 0.0011 0.0072 0.0013 0.0036 0.0005 0.0005 0.0007 0.0009 0.0016 0.0005 0.0004 0.0006 0.0009 0.001 0.0005
Bud Periphery 0.0003 0.0002 0.0001 0.0002 0.0008 0.0001 0.0011 0.0001 0.0001 0.0003 0.0004 0.0002 0.0001 0 0 0 0.0001 0
Bud Site 0.0015 0.0006 0.0008 0.0006 0.0098 0.0002 0.0068 0.0005 0.0003 0.0008 0.0008 0.0003 0.0003 0.0002 0.0001 0.0001 0.0002 0.0001
Cell Periphery 0.0003 0.0004 0.0002 0.0004 0.0013 0.0001 0.0008 0.0001 0.0002 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001 0
Cytoplasm 0.0009 0 0.0007 0 0.0007 0 0.0008 0 0.0003 0.0004 0.0008 0.0041 0 0 0 0 0 0
Cytoplasmic Foci 0.0155 0.0003 0.0033 0.0004 0.0171 0.0018 0.0218 0.0007 0.0018 0.0107 0.0066 0.0028 0.0027 0.0003 0.0006 0.0003 0.0024 0.0004
Eisosomes 0.0001 0 0.0001 0 0.0003 0 0.0001 0 0.0002 0.0001 0.0001 0 0 0 0 0 0 0
Endoplasmic Reticulum 0.0009 0 0.0001 0 0.0002 0 0.0009 0 0.0001 0.0003 0.0023 0.0004 0 0 0 0 0 0
Endosome 0.0078 0.0002 0.001 0.0001 0.0068 0.0001 0.0229 0.0007 0.0002 0.0066 0.035 0.0047 0.0005 0 0.0001 0.0001 0.0002 0
Golgi 0.0034 0.0001 0.0005 0 0.0044 0.0002 0.0097 0.001 0.0003 0.0074 0.0095 0.0035 0.0004 0 0 0 0.0003 0
Lipid Particles 0.0192 0.0016 0.0019 0.0012 0.0753 0.005 0.0299 0.0059 0.0047 0.0233 0.0302 0.011 0.0104 0.0007 0.0023 0.0007 0.0131 0.0014
Mitochondria 0.0014 0.0001 0.0002 0.0001 0.0295 0.0003 0.0207 0.0023 0.0014 0.0247 0.0594 0.0066 0.0002 0 0 0 0.0002 0
None 0.0021 0 0.0031 0 0.0014 0 0.0013 0 0.0067 0.0005 0.0014 0.0021 0.0004 0 0 0 0 0
Nuclear Periphery 0.0023 0 0.0001 0 0.0011 0.0001 0.0078 0.0001 0.0002 0.0024 0.0174 0.0027 0.0001 0 0 0.0004 0.0002 0
Nucleolus 0.7479 0.8298 0.8786 0.9163 0.6864 0.8308 0.7444 0.8378 0.8735 0.7925 0.6775 0.8528 0.8559 0.8728 0.8916 0.8863 0.8772 0.8835
Nucleus 0.0999 0.1576 0.0913 0.0742 0.0669 0.0991 0.0756 0.1474 0.0989 0.1018 0.0537 0.0771 0.0856 0.1079 0.0946 0.0894 0.0594 0.0831
Peroxisomes 0.0061 0.0001 0.0005 0.0001 0.0202 0.0003 0.0199 0.0004 0.0013 0.0096 0.0059 0.0016 0.0028 0 0.0001 0 0.0009 0.0001
Punctate Nuclear 0.0716 0.0028 0.0061 0.0039 0.0622 0.0602 0.0098 0.0016 0.0023 0.0116 0.0886 0.025 0.0386 0.0172 0.0095 0.0214 0.0442 0.0305
Vacuole 0.0019 0.0014 0.0005 0.0011 0.0029 0.0003 0.0046 0.0005 0.0004 0.0018 0.0012 0.0004 0.0004 0.0002 0.0003 0.0002 0.0003 0.0001
Vacuole Periphery 0.0007 0.0001 0.0001 0.0001 0.0013 0 0.0017 0.0002 0.0002 0.0021 0.002 0.0003 0.0001 0 0 0 0.0001 0

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 15.7284 21.6311 22.4716 16.5219 26.6671 12.092 16.9501 14.7615 11.9434 15.0516
Translational Efficiency 6.2707 3.9821 3.139 3.5926 2.7813 5.6419 2.6848 2.1137 3.0434 3.5888

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1419 1456 1332 330 2034 2062 1980 1868 3453 3518 3312 2198

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 796.42 931.20 988.79 1386.05 804.55 961.31 1127.92 1253.24 801.21 948.85 1071.97 1273.18
Standard Deviation 129.44 167.53 170.38 288.93 147.69 156.21 169.72 255.33 140.53 161.67 183.16 264.94
Intensity Change Log 2 — 0.225562 0.312135 0.799378 — 0.256820 0.487411 0.639409 — 0.241355 0.402877 0.721204

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000195 0.000224 0.000407 0.000481 0.000190 0.000189 0.000312 0.000426 0.000192 0.000204 0.000350 0.000434
Bud Neck 0.002281 0.002817 0.006180 0.017280 0.002623 0.002499 0.003718 0.011877 0.002482 0.002631 0.004708 0.012688
Bud Site 0.000761 0.000595 0.001327 0.003736 0.001056 0.000473 0.000583 0.002740 0.000935 0.000523 0.000882 0.002890
Cell Periphery 0.000047 0.000034 0.000042 0.000093 0.000106 0.000035 0.000017 0.000119 0.000082 0.000034 0.000027 0.000115
Cytoplasm 0.000670 0.000451 0.000439 0.000818 0.001592 0.000888 0.000065 0.002382 0.001213 0.000707 0.000216 0.002147
Cytoplasmic Foci 0.001277 0.000919 0.000507 0.002735 0.001254 0.001441 0.000270 0.001405 0.001263 0.001225 0.000366 0.001605
Eisosomes 0.000121 0.000099 0.000065 0.000119 0.000096 0.000092 0.000085 0.000146 0.000106 0.000095 0.000077 0.000142
Endoplasmic Reticulum 0.001445 0.001182 0.001248 0.000363 0.001572 0.000966 0.000437 0.000533 0.001520 0.001056 0.000763 0.000508
Endosome 0.000616 0.000655 0.000745 0.000385 0.001116 0.001713 0.000084 0.000968 0.000910 0.001275 0.000350 0.000881
Golgi 0.001082 0.000767 0.000966 0.000512 0.001290 0.000853 0.000274 0.000898 0.001205 0.000818 0.000552 0.000840
Lipid Particles 0.000287 0.000317 0.000127 0.000093 0.000439 0.000543 0.000033 0.000098 0.000377 0.000450 0.000071 0.000097
Mitochondria 0.001065 0.005060 0.000979 0.002676 0.001266 0.002673 0.001056 0.002446 0.001183 0.003661 0.001025 0.002480
Mitotic Spindle 0.006157 0.010043 0.033603 0.022186 0.006793 0.007250 0.011767 0.012709 0.006532 0.008406 0.020549 0.014132
None 0.001246 0.001100 0.001126 0.000739 0.004771 0.000515 0.000247 0.001269 0.003322 0.000757 0.000600 0.001190
Nuclear Periphery 0.000274 0.000230 0.000336 0.000483 0.000261 0.000263 0.000235 0.000494 0.000266 0.000249 0.000276 0.000493
Nuclear Periphery Foci 0.006140 0.004753 0.003895 0.000579 0.005295 0.003613 0.000590 0.000608 0.005642 0.004085 0.001919 0.000604
Nucleolus 0.659283 0.638968 0.630228 0.678713 0.616560 0.601846 0.701169 0.627855 0.634117 0.617210 0.672638 0.635490
Nucleus 0.303205 0.320176 0.305970 0.242040 0.346518 0.365204 0.266396 0.319629 0.328719 0.346568 0.282312 0.307980
Peroxisomes 0.011959 0.010040 0.009773 0.020374 0.005763 0.006790 0.011719 0.009030 0.008309 0.008135 0.010937 0.010734
Vacuole 0.001141 0.000911 0.001369 0.002967 0.000901 0.001176 0.000427 0.002116 0.001000 0.001067 0.000806 0.002244
Vacuole Periphery 0.000749 0.000659 0.000668 0.002627 0.000539 0.000978 0.000516 0.002251 0.000625 0.000846 0.000577 0.002308

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.25 -8.66 -3.20 -3.04 -1.65 0.12 -2.06 -10.92 -11.83 -1.87 -0.75 -4.87 -8.87 -8.58 -2.12
Bud Neck -1.48 -11.07 -9.79 -9.54 -7.39 0.42 -4.80 -14.13 -14.50 -12.35 -0.72 -11.06 -17.03 -16.99 -13.26
Bud Site 0.66 -3.88 -3.94 -4.07 -3.16 2.58 1.66 -3.19 -4.39 -4.03 2.48 -1.07 -4.61 -5.52 -4.37
Cell Periphery 1.34 0.14 -3.57 -4.50 -3.92 3.72 4.71 -0.67 -5.59 -7.01 3.95 4.52 -2.32 -6.58 -7.17
Cytoplasm 0.55 0.60 -1.21 -1.36 -1.37 1.22 2.78 -1.05 -2.22 -3.58 1.34 2.77 -1.89 -2.87 -3.72
Cytoplasmic Foci 0.68 1.84 -2.12 -2.52 -3.11 0.12 3.83 -0.22 -0.31 -3.30 0.51 4.11 -1.05 -1.45 -4.04
Eisosomes 2.77 7.74 0.06 -2.03 -5.44 1.10 3.43 -4.96 -5.42 -6.33 2.90 8.23 -3.90 -5.46 -7.84
Endoplasmic Reticulum 2.50 0.26 6.80 4.79 6.67 6.16 10.63 10.91 5.70 -1.55 6.41 8.83 13.73 8.27 4.34
Endosome -0.17 -0.48 0.79 0.83 0.93 -1.29 4.75 0.46 1.52 -2.82 -1.27 3.01 0.13 1.10 -1.80
Golgi 1.30 0.03 2.04 1.39 5.31 1.53 3.32 1.17 -0.07 -1.69 1.93 3.01 1.28 -0.06 -0.74
Lipid Particles -0.06 1.75 1.16 0.80 -0.27 -0.29 2.21 1.86 3.02 -2.35 -0.29 2.61 2.36 3.15 -0.95
Mitochondria -2.49 0.32 -5.80 1.17 -6.47 -1.65 0.77 -4.18 0.14 -6.10 -2.98 0.82 -6.15 1.21 -7.91
Mitotic Spindle -2.16 -10.16 -3.28 -2.64 1.84 -0.40 -3.31 -3.46 -3.03 -0.46 -1.72 -9.96 -4.79 -3.61 3.42
None 0.51 0.54 1.41 0.39 0.56 5.59 5.65 4.49 -4.09 -3.78 5.46 5.60 4.40 -2.42 -2.75
Nuclear Periphery 0.61 -1.49 -3.05 -3.84 -2.55 -0.07 0.34 -4.71 -4.56 -5.01 0.39 -0.76 -5.23 -5.82 -5.20
Nuclear Periphery Foci 1.36 1.98 6.41 4.80 6.30 2.52 8.88 9.52 5.05 -0.06 2.70 7.18 11.02 6.98 4.77
Nucleolus 2.82 4.88 1.19 -0.06 -1.03 2.22 -12.58 -0.26 -2.05 9.97 3.44 -6.91 1.78 -0.63 6.60
Nucleus -2.45 0.12 2.91 4.07 2.81 -3.05 12.38 2.82 5.40 -7.67 -3.86 9.89 2.03 4.83 -5.26
Peroxisomes 2.69 2.10 -4.92 -6.14 -5.90 -1.69 -11.20 -6.19 -4.45 5.17 0.62 -6.55 -4.69 -5.53 0.75
Vacuole 0.54 -0.85 -3.30 -3.84 -2.68 -0.84 0.25 -4.24 -2.73 -3.34 -0.26 -0.43 -4.74 -4.52 -3.72
Vacuole Periphery 0.31 0.16 -3.10 -3.51 -3.47 -1.63 0.06 -7.28 -4.08 -8.61 -1.12 0.18 -7.39 -6.04 -8.86
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Essential protein required for maturation of 18S rRNA; required for survival upon exposure to K1 killer toxin
Localization
Cell Percentages nucleolus (89%)
Cell Cycle Regulation No
Subcompartmental Group nucleolus-2

Fyv7

Fyv7


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Fyv7-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available