Standard name
Human Ortholog
Description DNA binding transcriptional activator; mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.09 0.15 0.27 0.35 0.51 0.62 0.71 – 0.64 0.69 0.49 0.62 0.45 0.49 0.65 0.7 0.72 0.67 0 0.05 0.09 0.23 0.24 0.2
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0.06 0 0.07 0 0 0 0 0 0
Endosome 0 0 0 0.11 0.08 0.06 0 – 0 0 0 0 0.05 0 0 0.05 0.06 0.08 0 0.06 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.22 0.06 0 0.16 0 0.24 0.21 – 0.39 0.26 0.59 0.43 0 0 0 0.07 0 0 0 0 0.06 0.05 0.07 0.07
Nucleus 0.67 0.53 0.48 0.26 0.09 0.06 0 – 0 0 0 0 0.42 0.39 0.29 0 0 0 0.57 0.5 0.35 0.26 0.22 0.17
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0.06 0.06 0 0.05 – 0 0 0 0.05 0 0 0 0 0 0 0.06 0.06 0.06 0.1 0.07 0.08
Vac/Vac Membrane 0.14 0.29 0.23 0.14 0.27 0.08 0.08 – 0 0.05 0 0 0.19 0.16 0.14 0.3 0.27 0.34 0.21 0.19 0.32 0.22 0.3 0.34
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 2 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 1 4 1 0 0 1
Bud 0 1 0 3 0 0 3 – 6 2 7 6 0 1 0 0 0 0 7 9 6 3 5 6
Bud Neck 0 0 6 2 5 4 7 – 3 6 1 1 1 1 0 0 1 1 1 3 4 0 3 4
Bud Site 0 0 0 0 0 1 0 – 3 0 3 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 2 – 0 3 0 0 0 0 0 3 0 4 0 0 0 0 0 0
Cytoplasm 44 71 69 67 99 167 259 – 199 180 164 203 33 116 123 227 157 173 26 32 38 27 70 53
Endoplasmic Reticulum 0 4 0 2 3 0 0 – 1 1 2 2 0 2 0 19 9 17 1 0 2 0 1 2
Endosome 7 18 7 21 16 16 7 – 3 5 2 3 4 3 2 17 12 20 12 33 7 2 7 8
Golgi 1 2 1 1 0 0 0 – 0 0 0 0 0 0 1 4 2 1 2 1 1 0 0 1
Mitochondria 106 29 3 31 8 65 75 – 120 67 200 142 0 2 0 22 4 5 10 25 25 5 19 20
Nucleus 319 245 121 51 18 15 15 – 10 5 13 6 31 93 55 5 7 5 352 300 142 31 66 48
Nuclear Periphery 0 0 1 0 0 0 0 – 0 0 3 0 0 0 0 2 0 0 2 6 1 0 0 3
Nucleolus 1 2 0 0 0 0 0 – 1 0 1 1 0 0 0 0 0 0 11 15 4 3 4 2
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0
SpindlePole 5 4 4 12 12 8 19 – 8 7 8 15 1 4 1 0 3 0 37 37 23 12 19 20
Vac/Vac Membrane 66 135 59 27 53 22 29 – 12 12 12 11 14 38 26 98 58 88 132 117 131 26 87 92
Unique Cell Count 477 464 253 194 194 270 365 310 259 338 329 74 239 190 326 218 257 618 602 407 121 296 275
Labelled Cell Count 549 512 273 217 214 298 416 366 289 416 391 84 260 208 397 253 314 618 602 407 121 296 275


Cytoplasm, Nucleus

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 4.1 5.0 5.7 5.1 5.3 4.4 4.3 – 3.8 4.0 3.4 3.8 5.5 5.4 5.3 6.7 7.0 6.7 4.9 5.2 5.6
Std Deviation (1e-4) 0.6 0.9 1.2 1.2 1.3 1.3 0.9 – 0.9 0.9 1.2 1.2 1.1 0.9 1.3 2.2 2.7 2.3 0.7 1.2 1.3
Intensity Change (Log2) – – – -0.14 -0.11 -0.38 -0.41 – -0.57 -0.51 -0.74 -0.59 -0.05 -0.07 -0.1 0.24 0.31 0.24 -0.21 -0.12 -0.01


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Cytoplasm 1.7 5.1 7.9 10.7 – 8.7 9.6 5.2 8.3 2.8 4.9 7.9 10.1 9.7 9.1
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 3.9 0 4.2
Endosome 3.5 2.6 0 0 – 0 0 0 0 0 0 0 1.5 1.5 2.5
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Mitochondria 5.8 0 0 0 – 0 0 0 0 0 0 0 3.3 0 0
Nucleus -4.6 -8.7 -11.0 -12.9 – -12.5 -12.1 -12.6 -13.3 -0.9 -2.0 -4.0 -13.4 -10.9 -12.0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0
SpindlePole 2.6 2.6 0 0 – 0 0 0 0 0 0 0 0 0 0
Vacuole -2.5 1.0 -4.8 -5.4 – -6.9 -6.1 -7.3 -7.3 -0.8 -2.1 -2.5 1.8 0.8 2.7

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration -1.3145 -0.7381 -1.0702 -0.7593 -0.8597 -1.0636 -0.2203 0.0104 0.2864 -0.1208 -0.4756 0.32 -0.0594 -0.1595 -0.5688 -0.388 -0.3417 -0.4833
Actin 0.0355 0.001 0.0131 0.0495 0.0804 0.0019 0.0125 0.0003 0.0075 0.001 0.0066 0.0108 0.0234 0.0004 0.018 0.01 0.0115 0.0039
Bud 0.0006 0.0012 0.0004 0.0005 0.0021 0.0001 0.0001 0.0001 0.0002 0.0001 0.0001 0.0002 0.0003 0.0067 0.0005 0.0002 0.0002 0.0005
Bud Neck 0.0036 0.0004 0.0009 0.0009 0.0013 0.002 0.0012 0.0037 0.0024 0.0188 0.0014 0.0059 0.0016 0.0004 0.0024 0.0015 0.0009 0.004
Bud Periphery 0.001 0.0041 0.0008 0.0011 0.0039 0.0001 0.0001 0.0001 0.0004 0.0001 0.0001 0.0004 0.0005 0.001 0.0007 0.0002 0.0002 0.0003
Bud Site 0.0103 0.0111 0.0023 0.0057 0.0026 0.0007 0.0012 0.0139 0.0026 0.0039 0.0003 0.0006 0.0014 0.0047 0.0023 0.0005 0.0005 0.0004
Cell Periphery 0.0006 0.0003 0.0002 0.0008 0.0003 0.0001 0.0003 0.0001 0.0014 0 0.0001 0.0001 0.0002 0.0001 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.1666 0.1946 0.176 0.1178 0.0348 0.1763 0.1178 0.1149 0.091 0.0685 0.0828 0.1262 0.1539 0.1958 0.1873 0.2052 0.1594 0.2241
Cytoplasmic Foci 0.0233 0.0113 0.0295 0.0441 0.0474 0.0196 0.0161 0.0051 0.0129 0.0108 0.0109 0.0071 0.0173 0.0148 0.0089 0.0323 0.0071 0.0152
Eisosomes 0.0005 0.0003 0.0003 0.0031 0.0005 0.0002 0.0003 0.0001 0.001 0.0001 0.0002 0.0002 0.0005 0.0001 0.0002 0.0001 0.0001 0.0001
Endoplasmic Reticulum 0.0055 0.0091 0.0076 0.005 0.002 0.0029 0.0043 0.0019 0.006 0.0019 0.0035 0.0049 0.0107 0.0044 0.0027 0.0062 0.0051 0.0042
Endosome 0.0208 0.009 0.0277 0.018 0.0931 0.0151 0.0072 0.002 0.0049 0.0037 0.0168 0.0069 0.0112 0.0039 0.0032 0.0169 0.0173 0.0081
Golgi 0.0046 0.0011 0.0111 0.0095 0.0643 0.009 0.0013 0.0001 0.0013 0.0003 0.002 0.0021 0.0021 0.0002 0.0006 0.0034 0.0024 0.0006
Lipid Particles 0.0104 0.0098 0.0154 0.0648 0.0534 0.0151 0.0033 0.0006 0.0035 0.0015 0.0067 0.005 0.0059 0.0007 0.0013 0.0049 0.0029 0.0008
Mitochondria 0.0346 0.0025 0.0178 0.0838 0.0999 0.0159 0.001 0.0005 0.0014 0.0004 0.001 0.0076 0.0022 0.001 0.001 0.0011 0.0016 0.0013
None 0.5504 0.5725 0.4015 0.414 0.3955 0.5003 0.4163 0.4903 0.4716 0.4423 0.4723 0.3942 0.338 0.5476 0.3869 0.2414 0.5165 0.3088
Nuclear Periphery 0.009 0.016 0.0252 0.0206 0.0047 0.0089 0.0192 0.0103 0.0164 0.0183 0.0269 0.0145 0.039 0.0116 0.0113 0.0377 0.0335 0.0224
Nucleolus 0.0068 0.002 0.0049 0.0022 0.0029 0.0027 0.0058 0.0053 0.007 0.0064 0.0059 0.0068 0.0031 0.0022 0.0038 0.0027 0.0027 0.0062
Nucleus 0.0861 0.1247 0.1964 0.0827 0.0397 0.1478 0.3003 0.2732 0.2642 0.2815 0.2723 0.3153 0.3203 0.1461 0.3178 0.3397 0.2009 0.3126
Peroxisomes 0.0034 0.0025 0.006 0.0333 0.0252 0.0042 0.0025 0.0004 0.0028 0.0003 0.0014 0.0029 0.0068 0.0004 0.0038 0.0011 0.0006 0.0009
Punctate Nuclear 0.0195 0.0176 0.0574 0.036 0.0409 0.0746 0.0869 0.0755 0.0993 0.1391 0.087 0.0854 0.0556 0.0552 0.0449 0.0923 0.0336 0.0819
Vacuole 0.0059 0.0063 0.0039 0.0034 0.0025 0.0018 0.0017 0.0015 0.0016 0.0006 0.0013 0.0021 0.0041 0.0024 0.0017 0.0018 0.0018 0.0025
Vacuole Periphery 0.001 0.0027 0.0015 0.0032 0.0024 0.0006 0.0004 0.0002 0.0007 0.0003 0.0007 0.0006 0.0019 0.0004 0.0004 0.0007 0.0011 0.0009

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 5.1005 9.6257 7.5186 7.7645 7.3478 11.3281 8.9641 11.7546 9.1135 8.828
Translational Efficiency 0.4711 0.2941 0.3659 0.3483 0.4043 0.3032 0.4548 0.2713 0.3503 0.4419

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1671 1360 341 1545 1863 2130 1585 165 3534 3490 1926 1710

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 545.51 660.09 922.57 752.07 668.67 694.68 792.32 812.90 610.44 681.20 815.38 757.94
Standard Deviation 64.63 91.61 95.75 101.61 75.48 91.05 85.09 93.84 93.59 92.82 100.27 102.48
Intensity Change Log 2 — 0.275057 0.758053 0.463261 — 0.055054 0.244789 0.281783 — 0.158066 0.498134 0.366153

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000078 0.000339 0.000696 0.000551 0.000068 0.000186 0.000240 0.000311 0.000073 0.000246 0.000321 0.000528
Bud Neck 0.011284 0.012802 0.003928 0.020748 0.003553 0.013365 0.012759 0.004079 0.007208 0.013146 0.011196 0.019140
Bud Site 0.005811 0.003854 0.001040 0.023624 0.000996 0.006573 0.004608 0.002506 0.003273 0.005513 0.003976 0.021586
Cell Periphery 0.000443 0.000149 0.000094 0.000213 0.000083 0.000139 0.000079 0.000117 0.000253 0.000143 0.000082 0.000204
Cytoplasm 0.400240* 0.226574* 0.022458 0.248876* 0.240915* 0.216282* 0.105000* 0.221157* 0.316249* 0.220293* 0.090386 0.246201*
Cytoplasmic Foci 0.111493 0.058741 0.002231 0.004934 0.035931 0.043941 0.000833 0.004355 0.071659 0.049708 0.001080 0.004878
Eisosomes 0.000209 0.000059 0.000060 0.000031 0.000031 0.000045 0.000015 0.000036 0.000115 0.000051 0.000023 0.000031
Endoplasmic Reticulum 0.001346 0.002640 0.009964 0.003055 0.001147 0.001997 0.002859 0.005051 0.001241 0.002247 0.004117 0.003247
Endosome 0.003003 0.004867 0.001010 0.003219 0.001334 0.005297 0.000479 0.001256 0.002123 0.005129 0.000573 0.003029
Golgi 0.001044 0.001598 0.000065 0.001474 0.000538 0.001487 0.000041 0.000055 0.000778 0.001530 0.000045 0.001337
Lipid Particles 0.013196 0.010830 0.001623 0.000983 0.003875 0.006741 0.000332 0.001001 0.008283 0.008334 0.000561 0.000985
Mitochondria 0.004342 0.009871 0.000682 0.004863 0.002198 0.011375 0.001476 0.000508 0.003212 0.010789 0.001336 0.004443
Mitotic Spindle 0.000696 0.008675 0.000158 0.036297 0.001922 0.007851 0.004169 0.001876 0.001342 0.008172 0.003459 0.032976
None 0.021138 0.023155 0.002875 0.008957 0.009654 0.014702 0.005068 0.010208 0.015084 0.017996 0.004680 0.009077
Nuclear Periphery 0.001065 0.002656 0.001740 0.002857 0.001630 0.003329 0.001989 0.001852 0.001363 0.003067 0.001945 0.002760
Nuclear Periphery Foci 0.000597 0.003029 0.000770 0.000806 0.000675 0.000893 0.000351 0.000851 0.000638 0.001725 0.000425 0.000810
Nucleolus 0.002889 0.010451 0.002984 0.001461 0.005553 0.009927 0.000877 0.000450 0.004294 0.010131 0.001250 0.001364
Nucleus 0.409289* 0.597528* 0.929048* 0.600390* 0.684083* 0.636907* 0.851426* 0.698172* 0.554150* 0.621562* 0.865169* 0.609825*
Peroxisomes 0.002964 0.007046 0.000299 0.000896 0.001414 0.005407 0.000102 0.000153 0.002147 0.006046 0.000137 0.000824
Vacuole 0.008361 0.013386 0.018115 0.034050 0.004166 0.012225 0.007000 0.045918 0.006150 0.012678 0.008968 0.035196
Vacuole Periphery 0.000510 0.001749 0.000160 0.001715 0.000234 0.001331 0.000298 0.000089 0.000365 0.001494 0.000274 0.001558

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -7.28 -9.74 -7.86 -2.14 4.69 -4.08 -6.71 -7.95 -6.42 -4.66 -7.85 -10.34 -9.45 -5.30 -1.51
Bud Neck -0.83 4.94 -3.88 -2.64 -8.06 -8.56 -6.56 -4.38 3.66 2.80 -6.00 -3.60 -7.01 -2.33 -3.02
Bud Site 1.67 3.65 -4.75 -6.25 -7.45 -4.97 -4.04 -5.49 0.69 -1.21 -2.61 -0.75 -6.59 -5.16 -6.12
Cell Periphery 7.70 8.59 7.29 -0.23 -2.23 -4.28 -0.16 -4.20 -0.46 -4.83 5.60 8.59 4.43 -0.67 -4.59
Cytoplasm 19.60 55.40 24.62 3.11 -26.35 3.04 21.72 5.67 4.33 -3.42 16.32 43.96 17.98 4.20 -17.74
Cytoplasmic Foci 10.02 28.64 29.44 16.49 -1.28 -2.68 17.63 14.02 17.07 -4.61 7.15 33.44 31.62 24.79 -8.03
Eisosomes 7.47 6.60 8.69 5.55 5.29 -5.57 4.65 -8.42 -6.22 -9.98 6.63 9.10 7.22 2.13 -6.98
Endoplasmic Reticulum -5.24 -12.86 -12.15 -8.62 8.55 -3.58 -11.35 -9.25 -8.59 -6.18 -5.93 -16.01 -16.83 -13.70 0.66
Endosome -2.53 2.03 1.03 4.33 -1.84 -6.52 3.84 -2.36 4.91 -5.81 -5.94 4.12 -0.11 6.28 -5.28
Golgi -2.15 7.55 1.22 2.49 -1.58 -2.22 1.89 1.69 4.45 -3.77 -2.86 4.77 0.66 2.64 -1.71
Lipid Particles 1.53 12.50 13.38 9.12 2.80 -4.65 9.22 5.02 9.81 -7.23 -0.28 16.11 14.76 14.08 -5.18
Mitochondria -5.10 7.45 1.65 6.09 -4.49 -7.91 2.18 4.24 9.58 3.64 -9.15 6.02 0.56 8.64 -3.23
Mitotic Spindle -5.26 0.16 -7.52 -3.84 -7.61 -4.06 -2.83 -1.89 -0.03 -0.47 -6.60 -3.34 -7.42 -4.37 -5.40
None -0.55 9.44 7.55 8.45 -4.80 -3.07 6.86 1.17 3.30 -2.24 -1.67 10.96 7.91 9.25 -4.24
Nuclear Periphery -4.98 -6.27 -14.92 -4.97 -8.39 -7.16 -6.77 -7.07 -1.76 -1.94 -8.89 -9.19 -14.74 -6.09 -6.45
Nuclear Periphery Foci -4.58 -2.67 -2.43 2.92 -0.68 0.34 1.17 -2.71 -3.36 -4.02 -4.17 -0.31 -2.09 1.21 -1.98
Nucleolus -8.82 -0.12 4.04 10.20 2.63 -3.23 6.77 7.74 12.10 3.02 -8.18 6.92 7.70 14.99 1.50
Nucleus -15.98 -52.35 -21.96 -3.65 26.32 5.15 -20.20 2.84 0.77 10.16 -8.35 -45.11 -8.90 -1.90 26.48
Peroxisomes -5.61 8.01 6.90 9.43 -0.95 -6.30 7.37 6.84 9.15 -2.81 -8.13 11.25 7.68 12.24 -2.42
Vacuole -4.56 -6.70 -17.77 -15.66 -9.77 -8.29 -8.01 -9.08 -8.65 -8.47 -8.73 -9.25 -20.17 -18.23 -16.58
Vacuole Periphery -2.51 5.70 -1.40 1.63 -2.92 -6.40 0.21 3.64 7.06 0.80 -5.29 1.78 -1.97 2.41 -2.56
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description DNA binding transcriptional activator; mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain
Localization
Cell Percentages nucleus (56%)
Cell Cycle Regulation No
Subcompartmental Group nucleus-3

Cha4

Cha4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Cha4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available