Standard name
Human Ortholog
Description Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.61 0.59 0.51 0.64 0.87 0.94 0.93 0.91 – 0.92 0.87 0.85 0.66 0.65 0.72 0.9 0.81 0.82 0.06 0.07 0 0.07 0.1 0.09
Endoplasmic Reticulum 0.32 0.32 0.36 0.31 0 0 0 0 – 0 0 0 0.28 0.3 0.25 0 0 0 0.53 0.49 0.67 0.59 0.53 0.37
Endosome 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0 0.05 0.07 – 0.11 0.18 0.16 0 0 0 0.08 0 0 0 0 0 0.05 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0.17 0.18 0.11 0.14 0.09 0.07 0.06 – 0 0 0.05 0.09 0.09 0 0.06 0.13 0.13 0.35 0.36 0.21 0.24 0.26 0.43
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 1 4 5 2 0 0 1 – 1 1 1 8 8 3 1 3 4 0 1 7 1 9 6
Bud 0 2 2 2 1 4 6 10 – 18 26 18 1 1 0 0 0 1 0 1 3 3 11 10
Bud Neck 0 0 0 0 0 0 0 2 – 0 0 2 1 1 5 1 0 0 0 1 1 1 6 4
Bud Site 0 0 0 0 0 0 0 0 – 1 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 4 1 0 1 2 – 2 0 6 16 16 21 1 3 1 0 0 0 0 1 0
Cytoplasm 23 93 237 270 532 672 943 972 – 979 524 845 392 392 461 65 177 163 5 15 18 24 63 61
Endoplasmic Reticulum 12 50 165 130 23 2 5 2 – 3 2 5 167 181 162 0 8 6 50 104 358 219 347 251
Endosome 0 1 13 5 17 4 4 12 – 6 2 7 1 1 2 0 5 4 0 3 9 3 6 8
Golgi 0 0 0 0 1 0 0 0 – 0 1 0 1 1 1 0 0 0 0 0 2 0 2 1
Mitochondria 1 1 1 1 2 28 53 70 – 119 110 161 0 0 0 6 7 7 2 3 9 18 25 21
Nucleus 1 0 1 0 1 1 5 2 – 1 3 5 2 2 3 1 2 3 0 0 0 0 0 0
Nuclear Periphery 0 1 3 4 0 1 3 7 – 3 2 16 0 0 0 0 0 1 0 2 4 2 3 4
Nucleolus 0 0 0 0 1 1 0 4 – 1 2 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 1 1 4 – 5 0 9 0 0 0 0 0 1 0 0 0 1 1 3
Vac/Vac Membrane 1 26 85 48 85 63 76 64 – 37 23 51 56 53 27 4 28 25 33 77 113 91 169 293
Unique Cell Count 38 157 464 422 609 714 1014 1066 1063 602 997 593 602 639 72 218 198 95 214 534 373 655 676
Labelled Cell Count 38 175 511 469 666 777 1097 1152 1176 696 1126 645 656 685 79 233 216 95 214 534 373 655 676


Endoplasmic Reticulum

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 5.5 6.7 6.7 6.9 6.1 4.4 3.8 4.1 – 3.5 3.8 3.6 8.0 8.0 7.4 5.2 6.3 7.3 9.0 8.5 7.9
Std Deviation (1e-4) 1.2 1.4 1.5 1.7 1.6 0.9 0.9 0.9 – 0.8 1.0 0.8 1.3 1.3 1.4 1.1 1.3 1.4 1.7 1.8 1.5
Intensity Change (Log2) – – – 0.05 -0.13 -0.62 -0.81 -0.71 – -0.95 -0.84 -0.91 0.24 0.24 0.14 -0.37 -0.1 0.11 0.41 0.34 0.24


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 0 0 0 0 – 0 0 0 0.7 0.7 0 0 0 0
Bud 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Cell Periphery 0 0 0 0 0 – 0 0 0 3.6 3.5 3.9 0 0 0
Cytoplasm 3.9 13.1 17.2 18.6 17.7 – 18.3 12.9 13.7 4.9 4.6 7.2 6.2 7.5 7.5
Endoplasmic Reticulum -1.5 -13.6 0 0 0 – 0 0 0 -2.6 -1.9 -3.7 -6.1 -8.9 -8.8
Endosome -1.7 0 0 0 0 – 0 0 0 -3.7 -3.7 -3.5 0 -0.4 -0.6
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 – 0 0 0 0 0 0 0 0 0
Vacuole -2.9 -1.9 -4.8 -6.2 -7.5 – -9.8 -7.8 -8.1 -4.2 -4.6 -7.7 -2.7 -1.8 -1.8

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration – – – – – – – – – – – – – – – – – –
Actin – – – – – – 0.0098 0.0004 0.0107 0.0003 0.0304 0.0003 0.0068 0.0013 0.0132 0.0283 0.0001 0.0001
Bud – – – – – – 0.0004 0.0001 0.0001 0.0002 0.0002 0.0001 0.0002 0.0002 0.0011 0.0004 0.0001 0
Bud Neck – – – – – – 0.0004 0.0002 0.0008 0.0004 0.0023 0.0009 0.0008 0.0002 0.0006 0.0134 0.0007 0.0005
Bud Periphery – – – – – – 0.0008 0.0001 0.0002 0.0003 0.0003 0.0003 0.0002 0.0004 0.0037 0.0006 0.0001 0.0001
Bud Site – – – – – – 0.0016 0.0011 0.0026 0.0006 0.0007 0.0002 0.003 0.0011 0.0043 0.0054 0.0001 0.0001
Cell Periphery – – – – – – 0.0011 0.0009 0.0009 0.0009 0.0009 0.0006 0.0006 0.001 0.0015 0.0007 0.0004 0.0002
Cytoplasm – – – – – – 0.1784 0.3999 0.3028 0.308 0.2953 0.3173 0.2083 0.382 0.2923 0.3024 0.2711 0.3279
Cytoplasmic Foci – – – – – – 0.026 0.0107 0.0148 0.0125 0.0376 0.0109 0.0166 0.0196 0.0162 0.0133 0.0131 0.009
Eisosomes – – – – – – 0.0002 0 0.0001 0 0.0001 0 0.0001 0.0002 0.0002 0.0004 0 0
Endoplasmic Reticulum – – – – – – 0.4457 0.3503 0.4712 0.4282 0.3015 0.4393 0.524 0.3805 0.4317 0.456 0.4565 0.4979
Endosome – – – – – – 0.0701 0.052 0.0572 0.0808 0.0691 0.0641 0.0535 0.0426 0.0589 0.0658 0.0687 0.0385
Golgi – – – – – – 0.0109 0.0009 0.0019 0.0013 0.0185 0.0058 0.0051 0.0008 0.0029 0.0033 0.0009 0.0004
Lipid Particles – – – – – – 0.0243 0.0058 0.0091 0.0057 0.0087 0.0046 0.0175 0.0048 0.009 0.0044 0.0068 0.0018
Mitochondria – – – – – – 0.0172 0.0003 0.0015 0.0006 0.002 0.0015 0.0012 0.0035 0.0041 0.0012 0.0004 0.0003
None – – – – – – 0.1095 0.1196 0.0479 0.0196 0.0575 0.0233 0.0581 0.0945 0.0685 0.0233 0.0685 0.0441
Nuclear Periphery – – – – – – 0.033 0.0186 0.0216 0.0197 0.0463 0.0289 0.048 0.018 0.0293 0.0205 0.0337 0.0317
Nucleolus – – – – – – 0.0009 0.0002 0.0006 0.0002 0.0002 0.0001 0.0009 0.0002 0.0002 0.0004 0.0001 0.0001
Nucleus – – – – – – 0.0057 0.0047 0.0117 0.0041 0.0099 0.0131 0.0168 0.0084 0.0042 0.0032 0.004 0.0086
Peroxisomes – – – – – – 0.0038 0.0001 0.0011 0.0001 0.0157 0.0001 0.0025 0.0033 0.003 0.0023 0.0001 0
Punctate Nuclear – – – – – – 0.0075 0.0012 0.0017 0.0009 0.0012 0.0005 0.0073 0.0012 0.0017 0.0017 0.0006 0.0007
Vacuole – – – – – – 0.049 0.0313 0.0377 0.1092 0.0969 0.0826 0.0256 0.0339 0.0477 0.0513 0.0658 0.0345
Vacuole Periphery – – – – – – 0.0037 0.0016 0.0036 0.0062 0.0046 0.0056 0.0028 0.0021 0.0055 0.0018 0.0082 0.0034

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 21.7377 24.8732 19.0337 20.4277 21.9834 26.0708 19.2549 15.9132 15.9209 23.1137
Translational Efficiency 0.4922 0.2627 0.4319 0.3895 0.3867 0.3669 0.3024 0.3303 0.3382 0.3094

Hit Data

Dataset Hit
Protein Concentration –
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
79 334 1716 1025 1940 598 1992 1147 2019 932 3708 2172

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 947.63 954.70 974.32 920.14 738.23 900.25 993.04 977.39 746.42 919.76 984.38 950.37
Standard Deviation 131.05 173.92 145.01 131.59 107.35 139.19 147.94 144.57 115.73 154.76 146.89 141.52
Intensity Change Log 2 — 0.010724 0.040072 -0.042470 — 0.286255 0.427781 0.404864 — 0.137896 0.222776 0.170638

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000241 0.000350 0.000336 0.003857 0.000502 0.000195 0.001248 0.002016 0.000492 0.000251 0.000826 0.002885
Bud Neck 0.007025 0.002840 0.004363 0.007892 0.010655 0.005144 0.006758 0.005244 0.010513 0.004318 0.005650 0.006494
Bud Site 0.032005 0.004017 0.004790 0.026388 0.007419 0.005012 0.007825 0.015777 0.008381 0.004655 0.006421 0.020785
Cell Periphery 0.000313 0.000456 0.000599 0.001335 0.001361 0.000695 0.001253 0.000870 0.001320 0.000610 0.000951 0.001090
Cytoplasm 0.210768* 0.215617* 0.218646* 0.247630* 0.238522* 0.103570* 0.136661* 0.197607* 0.237436* 0.143724* 0.174602* 0.221213*
Cytoplasmic Foci 0.093491 0.072531 0.027154 0.054773 0.082090 0.049336 0.011132 0.044070 0.082536 0.057648 0.018547 0.049121
Eisosomes 0.000131 0.000076 0.000123 0.000475 0.000650 0.000200 0.000539 0.000338 0.000630 0.000156 0.000346 0.000403
Endoplasmic Reticulum 0.090332 0.336240* 0.492458* 0.242758* 0.353035* 0.516398* 0.663679* 0.433970* 0.342756* 0.451835* 0.584441* 0.343735*
Endosome 0.027797 0.036757 0.011551 0.016047 0.035770 0.039695 0.009193 0.016871 0.035458 0.038642 0.010284 0.016482
Golgi 0.000878 0.002060 0.000791 0.004810 0.010099 0.005613 0.001594 0.001950 0.009738 0.004340 0.001222 0.003299
Lipid Particles 0.010024 0.032180 0.017917 0.027374 0.055313 0.032175 0.017006 0.029046 0.053541 0.032177 0.017428 0.028257
Mitochondria 0.016450 0.000509 0.000970 0.001032 0.007718 0.002311 0.003325 0.000737 0.008060 0.001665 0.002235 0.000876
Mitotic Spindle 0.007292 0.000849 0.001532 0.005828 0.001602 0.000166 0.000642 0.002493 0.001825 0.000410 0.001054 0.004067
None 0.000143 0.000657 0.002367 0.002489 0.003116 0.000519 0.002739 0.000919 0.003000 0.000568 0.002567 0.001660
Nuclear Periphery 0.003657 0.005080 0.025247 0.005423 0.003144 0.006486 0.013104 0.007715 0.003164 0.005982 0.018724 0.006634
Nuclear Periphery Foci 0.009541 0.030856 0.041006 0.036909 0.003556 0.006309 0.017063 0.042457 0.003791 0.015106 0.028144 0.039839
Nucleolus 0.000395 0.000460 0.000583 0.000439 0.000811 0.000456 0.000255 0.000231 0.000795 0.000457 0.000407 0.000330
Nucleus 0.074538 0.019587 0.092167 0.060130 0.032308 0.009787 0.040449 0.035064 0.033961 0.013299 0.064383 0.046893
Peroxisomes 0.003152 0.002003 0.000609 0.002203 0.002855 0.001769 0.000861 0.001004 0.002867 0.001853 0.000744 0.001570
Vacuole 0.409202* 0.234651* 0.056167 0.250708* 0.145010 0.207313* 0.063808 0.160261 0.155347 0.217110* 0.060272 0.202944*
Vacuole Periphery 0.002627 0.002224 0.000623 0.001499 0.004462 0.006852 0.000866 0.001360 0.004391 0.005193 0.000754 0.001425

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.51 -2.06 -4.16 -3.96 -3.98 1.80 -2.63 -3.13 -3.97 -1.21 1.41 -1.88 -4.73 -5.57 -3.81
Bud Neck 0.83 0.38 -0.53 -5.05 -3.20 4.11 2.90 5.03 -0.25 1.42 5.54 4.42 4.16 -2.64 -0.91
Bud Site 1.83 1.76 0.16 -7.23 -6.86 1.28 -0.45 -3.76 -4.07 -3.31 2.35 1.25 -6.08 -7.60 -7.29
Cell Periphery -1.97 -4.22 -6.78 -5.22 -4.28 4.44 0.62 3.62 -1.23 3.02 5.24 2.57 2.56 -4.22 -0.09
Cytoplasm -0.57 -0.77 -1.87 -2.12 -2.98 15.96 14.71 3.71 -10.44 -7.83 11.05 9.53 1.39 -9.65 -7.60
Cytoplasmic Foci 1.37 5.79 3.49 3.39 -8.34 6.83 24.83 10.34 1.01 -13.39 5.78 22.86 10.90 2.66 -15.38
Eisosomes 2.58 -0.12 -6.75 -8.07 -6.71 6.12 0.65 3.93 -1.93 1.18 7.31 2.64 3.87 -4.90 -0.20
Endoplasmic Reticulum -7.80 -14.58 -4.12 6.45 21.60 -9.09 -25.09 -2.54 6.42 18.01 -7.08 -22.12 4.20 10.30 27.01
Endosome -1.51 1.59 1.29 7.89 -2.06 -1.27 18.48 11.87 7.84 -6.17 -1.34 18.36 13.93 10.84 -6.07
Golgi -1.54 -0.19 -2.58 -1.24 -2.67 3.78 14.02 13.20 3.63 -0.71 5.92 14.86 9.24 1.89 -2.74
Lipid Particles -5.40 -3.91 -5.56 2.08 -2.76 6.63 16.08 10.01 1.24 -5.68 7.04 16.49 11.69 2.46 -6.09
Mitochondria 1.01 0.97 0.98 -2.65 0.32 5.51 4.95 8.96 2.57 5.41 6.49 6.23 8.02 2.11 5.26
Mitotic Spindle 0.88 0.70 0.11 -2.90 -2.14 2.14 1.35 -0.81 -2.45 -1.90 1.95 0.73 -1.88 -3.92 -2.86
None -1.54 -3.52 -1.81 -1.27 0.34 4.87 0.61 3.75 -0.95 2.38 5.08 0.72 2.25 -1.56 1.57
Nuclear Periphery -1.37 -9.79 -1.48 -0.05 10.10 -2.01 -8.28 -4.58 -0.49 3.96 -2.50 -13.77 -5.08 -0.28 10.25
Nuclear Periphery Foci -4.83 -9.23 -6.63 -0.50 2.83 -3.51 -10.23 -14.90 -13.37 -8.63 -7.75 -19.90 -19.32 -10.10 -4.42
Nucleolus -0.83 -1.60 -0.33 0.39 1.18 0.61 8.33 7.95 1.41 -0.08 1.16 4.24 5.38 1.35 1.09
Nucleus 2.96 -1.37 0.26 -12.74 5.85 14.76 -4.46 -2.39 -13.23 1.98 12.58 -13.18 -7.64 -18.65 5.73
Peroxisomes 0.34 1.25 0.49 0.17 -2.65 2.26 10.08 9.51 2.04 -1.10 2.01 11.43 5.23 1.07 -2.85
Vacuole 5.69 10.94 3.91 -4.59 -27.49 -5.45 12.93 -5.86 0.96 -15.31 -6.40 17.45 -12.55 -3.22 -29.72
Vacuole Periphery -0.04 1.04 0.63 2.40 -1.68 -2.38 14.04 4.75 4.78 -0.56 -1.20 16.09 7.43 5.35 -1.19
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor
Localization
Cell Percentages ER (65%)
Cell Cycle Regulation No
Subcompartmental Group ER-3

Zrt2

Zrt2


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Zrt2-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available