Standard name
Human Ortholog
Description Spermine synthase; required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
DOWNLOAD

Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Bud Site 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – – – – – – –
Cell Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Cytoplasm 0.98 0.96 1.0 1.0 0.98 0.93 0.82 – 0.78 0.67 0.62 0.63 0.99 0.99 1.0 – – – 0.97 0.92 0.98 0.96 0.95 0.94
Endoplasmic Reticulum 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Endosome 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Mitochondria 0 0 0 0 0 0.07 0.1 – 0.3 0.4 0.5 0.37 0 0 0 – – – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0.05 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0.13 – 0.06 0.06 0.1 0.08 0 0 0 – – – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 1 0 0 – 0 0 0 0 0 0 0 – – – 2 0 0 0 0 0
Bud 0 8 1 0 0 0 1 – 1 2 1 1 0 0 0 – – – 0 0 0 0 1 0
Bud Neck 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 1
Bud Site 0 0 0 0 0 0 0 – 0 1 0 0 0 0 0 – – – – – – – – –
Cell Periphery 1 2 4 0 1 1 1 – 2 2 3 1 2 3 2 – – – 0 0 0 0 0 0
Cytoplasm 235 305 235 87 161 117 135 – 129 99 96 148 353 443 467 – – – 224 318 232 272 413 435
Endoplasmic Reticulum 4 1 0 0 0 0 0 – 0 0 0 1 0 0 0 – – – 0 0 0 0 2 2
Endosome 0 0 0 0 0 0 0 – 1 0 0 0 1 0 0 – – – 1 4 0 0 2 4
Golgi 1 0 0 0 0 0 1 – 0 0 0 0 1 0 0 – – – 0 2 0 0 1 0
Mitochondria 0 13 0 0 1 9 17 – 50 59 78 88 0 2 1 – – – 0 3 0 2 4 3
Nucleus 3 0 1 0 0 6 3 – 5 5 4 7 0 2 0 – – – 0 2 0 1 1 2
Nuclear Periphery 0 0 0 0 0 0 0 – 0 2 0 2 0 0 0 – – – 0 2 0 1 0 0
Nucleolus 0 0 0 0 0 0 0 – 0 1 0 1 0 0 0 – – – 0 0 0 0 0 0
Peroxisomes 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 0
SpindlePole 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 – – – 0 0 0 0 0 3
Vac/Vac Membrane 1 1 1 0 2 1 21 – 10 9 16 18 2 1 1 – – – 1 7 0 1 1 0
Unique Cell Count 241 318 236 87 164 126 165 166 147 156 236 356 447 469 232 345 237 285 435 463
Labelled Cell Count 245 330 242 87 166 134 179 198 180 198 267 359 451 471 232 345 237 285 435 463


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 7.0 4.8 7.5 6.8 7.6 5.8 5.9 – 5.0 5.1 4.9 5.4 7.4 7.4 7.1 – – – 8.2 8.1 7.9
Std Deviation (1e-4) 0.7 0.7 0.9 1.0 2.1 1.0 1.6 – 1.1 0.9 0.7 1.0 1.3 1.1 1.1 – – – 1.3 1.3 1.4
Intensity Change (Log2) – – – -0.14 0.01 -0.39 -0.35 – -0.58 -0.58 -0.63 -0.47 -0.03 -0.03 -0.08 – – – 0.12 0.11 0.07


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Actin – – – – – – – – – – – – – – –
Bud – – – – – – – – – – – – – – –
Bud Neck – – – – – – – – – – – – – – –
Bud Site – – – – – – – – – – – – – – –
Cell Periphery – – – – – – – – – – – – – – –
Cyto – – – – – – – – – – – – – – –
Endoplasmic Reticulum – – – – – – – – – – – – – – –
Endosome – – – – – – – – – – – – – – –
Golgi – – – – – – – – – – – – – – –
Mitochondria – – – – – – – – – – – – – – –
Nuclear Periphery – – – – – – – – – – – – – – –
Nuc – – – – – – – – – – – – – – –
Nucleolus – – – – – – – – – – – – – – –
Peroxisomes – – – – – – – – – – – – – – –
SpindlePole – – – – – – – – – – – – – – –
Vac – – – – – – – – – – – – – – –
Cortical Patches – – – – – – – – – – – – – – –
Cytoplasm – – – – – – – – – – – – – – –
Nucleus – – – – – – – – – – – – – – –
Vacuole – – – – – – – – – – – – – – –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 5.0458 6.409 6.0298 5.6746 6.0134 6.0387 4.7109 5.4594 5.2784 5.005 4.6702 5.3624 2.043 3.1598 2.7507 2.5855 2.86 2.7685
Actin 0.0502 0.0057 0.0155 0.0025 0.0188 0.0068 0.0702 0.0045 0.0188 0.0065 0.0051 0.001 0.0339 0.0009 0.0107 0.0004 0.0286 0.0073
Bud 0.0009 0.0034 0.0015 0.0016 0.0025 0.0006 0.0008 0.0053 0.0029 0.0006 0.0008 0.0001 0.0002 0.0001 0.0002 0.0001 0.0002 0.0016
Bud Neck 0.0017 0.0003 0.0013 0.0029 0.0012 0.0009 0.0022 0.0004 0.0004 0.0006 0.0015 0.0004 0.0015 0.0001 0.0003 0.0002 0.0007 0.0021
Bud Periphery 0.0013 0.0067 0.002 0.0063 0.006 0.0017 0.0011 0.0056 0.0031 0.0005 0.0016 0 0.0002 0 0.0001 0.0001 0.0004 0.0008
Bud Site 0.0104 0.0083 0.0114 0.0008 0.0051 0.0018 0.0114 0.0035 0.0021 0.0006 0.0101 0.0001 0.0008 0.0004 0.0021 0.0001 0.0007 0.0004
Cell Periphery 0.0007 0.0008 0.0007 0.0003 0.0005 0.0001 0.0004 0.0004 0.0002 0.0001 0.0011 0 0.0001 0.0001 0.0001 0.0001 0.0001 0.0001
Cytoplasm 0.5637 0.8323 0.715 0.8534 0.7481 0.8225 0.4508 0.8067 0.6308 0.6848 0.7893 0.7286 0.6867 0.8019 0.7426 0.7017 0.5372 0.7679
Cytoplasmic Foci 0.0215 0.0047 0.0098 0.008 0.0074 0.0081 0.0338 0.0056 0.0168 0.0073 0.0221 0.0112 0.0143 0.0042 0.0046 0.004 0.0075 0.0125
Eisosomes 0.0005 0.0001 0.0003 0.0001 0.0002 0 0.0005 0.0003 0.0001 0.0001 0.0004 0 0.0003 0 0 0 0.0003 0.0005
Endoplasmic Reticulum 0.0056 0.0077 0.0038 0.0031 0.01 0.0014 0.0049 0.0026 0.0049 0.0105 0.0016 0.0019 0.0059 0.001 0.0024 0.0017 0.0021 0.0027
Endosome 0.0323 0.0046 0.0149 0.002 0.0296 0.0116 0.0156 0.0016 0.0153 0.014 0.0471 0.0083 0.0147 0.0005 0.0015 0.001 0.0188 0.0044
Golgi 0.012 0.0004 0.0067 0.0006 0.0082 0.0068 0.0074 0.0004 0.0027 0.0096 0.0068 0.0013 0.005 0.0001 0.0005 0.0001 0.0115 0.0015
Lipid Particles 0.0162 0.0004 0.006 0.0027 0.0214 0.0041 0.0086 0.0009 0.0011 0.0058 0.0029 0.0019 0.0055 0 0.0003 0.0001 0.0198 0.0045
Mitochondria 0.0111 0.0004 0.0102 0.0033 0.0334 0.008 0.0171 0.0007 0.0015 0.0181 0.0179 0.0004 0.0015 0.0001 0.0002 0.0001 0.0083 0.0008
None 0.1944 0.1162 0.1722 0.0903 0.0801 0.1163 0.3256 0.1545 0.2726 0.2302 0.0828 0.2387 0.2066 0.1863 0.2257 0.2858 0.3468 0.1768
Nuclear Periphery 0.0087 0.0013 0.0032 0.0019 0.0083 0.001 0.0069 0.0014 0.0043 0.003 0.0008 0.0008 0.0034 0.0004 0.001 0.0006 0.0033 0.0031
Nucleolus 0.004 0.0001 0.0005 0.002 0.002 0.0001 0.0005 0.0002 0.0004 0.0001 0.0002 0 0.0003 0 0.0001 0 0.0003 0.0004
Nucleus 0.0116 0.0019 0.0065 0.0035 0.004 0.0021 0.0044 0.003 0.0036 0.0034 0.0023 0.0019 0.0023 0.0027 0.0025 0.0026 0.0014 0.0034
Peroxisomes 0.0294 0.0002 0.0126 0.005 0.003 0.0032 0.019 0.0004 0.0058 0.0014 0.0027 0.0019 0.0083 0.0001 0.0008 0.0001 0.0073 0.0028
Punctate Nuclear 0.0159 0.0012 0.0035 0.0086 0.0018 0.002 0.016 0.0013 0.0032 0.0008 0.001 0.0009 0.0075 0.0007 0.004 0.0009 0.0033 0.0054
Vacuole 0.0065 0.0031 0.0016 0.0009 0.0052 0.0006 0.0018 0.0007 0.0077 0.0014 0.0014 0.0003 0.0008 0.0003 0.0004 0.0004 0.0007 0.0005
Vacuole Periphery 0.0015 0.0002 0.0008 0.0003 0.0033 0.0003 0.001 0.0001 0.0016 0.0007 0.0004 0.0001 0.0003 0 0.0001 0.0001 0.0007 0.0002

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 30.5483 31.6776 27.559 23.4929 15.8429 28.0889 23.7458 24.5993 16.5372 26.1155
Translational Efficiency 1.0658 0.7538 0.7776 0.7708 0.9164 0.8208 1.0077 0.6251 1.0514 0.8478

Hit Data

Dataset Hit
Protein Concentration ✔
Protein Localization ✘
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
1963 693 2600 1285 1400 2033 2384 1661 3363 2726 4984 2946

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 768.93 907.84 958.43 942.98 782.62 942.95 979.00 883.33 774.63 934.02 968.27 909.35
Standard Deviation 178.37 118.81 114.91 123.98 105.03 111.17 122.19 110.61 152.34 114.19 118.89 120.32
Intensity Change Log 2 — 0.239586 0.317821 0.294375 — 0.268869 0.322997 0.174641 — 0.254431 0.320434 0.235221

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000066 0.000301 0.000107 0.001769 0.000127 0.000134 0.000143 0.000809 0.000092 0.000176 0.000124 0.001228
Bud Neck 0.006661 0.004592 0.003700 0.007860 0.003086 0.006693 0.003110 0.011773 0.005173 0.006159 0.003418 0.010067
Bud Site 0.003812 0.008242 0.007906 0.037399 0.003384 0.008923 0.006880 0.025373 0.003634 0.008750 0.007415 0.030618
Cell Periphery 0.000182 0.000091 0.000051 0.000128 0.000073 0.000052 0.000042 0.000218 0.000137 0.000062 0.000046 0.000179
Cytoplasm 0.625831* 0.660261* 0.647929* 0.524899* 0.679474* 0.748886* 0.739755* 0.542575* 0.648162* 0.726356* 0.691852* 0.534865*
Cytoplasmic Foci 0.092291 0.135135 0.006467 0.022237 0.114049 0.068837 0.005934 0.025084 0.101349 0.085691 0.006212 0.023842
Eisosomes 0.000106 0.000039 0.000010 0.000037 0.000043 0.000025 0.000010 0.000070 0.000080 0.000029 0.000010 0.000056
Endoplasmic Reticulum 0.001260 0.001043 0.000883 0.001612 0.000882 0.000284 0.000422 0.000896 0.001103 0.000477 0.000663 0.001208
Endosome 0.005750 0.007914 0.000742 0.008538 0.005123 0.002461 0.001057 0.009748 0.005489 0.003847 0.000893 0.009220
Golgi 0.001138 0.001408 0.000064 0.003983 0.001088 0.000988 0.000178 0.003636 0.001117 0.001094 0.000118 0.003787
Lipid Particles 0.003821 0.001746 0.000336 0.001607 0.001894 0.000740 0.000303 0.001882 0.003019 0.000996 0.000320 0.001762
Mitochondria 0.000980 0.000976 0.000403 0.005829 0.002623 0.000983 0.000532 0.003962 0.001664 0.000982 0.000464 0.004776
Mitotic Spindle 0.000807 0.003734 0.003284 0.070979 0.001125 0.003258 0.015381 0.024619 0.000939 0.003379 0.009070 0.044841
None 0.021504 0.003131 0.005353 0.004027 0.002878 0.003967 0.007115 0.005766 0.013750 0.003755 0.006196 0.005008
Nuclear Periphery 0.000500 0.000229 0.000763 0.001417 0.000310 0.000118 0.000794 0.000621 0.000421 0.000146 0.000778 0.000968
Nuclear Periphery Foci 0.001519 0.002026 0.000715 0.002631 0.000629 0.000215 0.000369 0.000595 0.001148 0.000675 0.000549 0.001483
Nucleolus 0.003131 0.000470 0.000114 0.000571 0.000581 0.000311 0.000243 0.002155 0.002070 0.000352 0.000176 0.001464
Nucleus 0.171037* 0.089958 0.287737* 0.105751 0.125508 0.108738 0.162977* 0.195175* 0.152083* 0.103964 0.228060* 0.156170*
Peroxisomes 0.001127 0.002943 0.000121 0.003973 0.000853 0.001293 0.000291 0.002873 0.001013 0.001712 0.000202 0.003353
Vacuole 0.057874 0.075269 0.033217 0.189476 0.055333 0.042645 0.054033 0.139532 0.056816 0.050938 0.043174 0.161317
Vacuole Periphery 0.000603 0.000491 0.000099 0.005277 0.000937 0.000451 0.000432 0.002638 0.000742 0.000461 0.000259 0.003789

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -5.43 -7.33 -2.91 -1.67 -2.53 -0.16 0.18 -1.76 -1.76 -1.86 -2.72 -1.40 -3.23 -2.63 -2.99
Bud Neck 2.58 4.56 2.97 -0.01 -1.33 -4.72 -1.00 -5.50 -1.75 -5.19 -1.44 4.01 -2.51 -0.98 -5.14
Bud Site -4.68 -2.66 -5.15 -2.66 -3.42 -4.70 -1.31 -7.75 -4.30 -6.82 -5.83 -2.84 -9.26 -4.77 -7.26
Cell Periphery 5.33 7.81 5.83 1.23 -4.04 4.31 8.95 -6.29 -8.07 -9.49 7.52 9.27 1.50 -7.55 -10.04
Cytoplasm -2.38 5.04 22.31 19.61 19.65 -9.06 6.49 19.60 30.30 15.22 -12.78 7.51 28.05 39.36 23.62
Cytoplasmic Foci -6.36 29.82 27.29 20.38 -5.55 9.85 28.25 23.63 17.72 -12.41 4.71 41.01 35.21 26.77 -13.24
Eisosomes 4.17 5.98 4.17 -0.23 -20.28 6.73 11.65 -4.14 -10.27 -14.21 5.58 7.26 3.02 -10.47 -19.76
Endoplasmic Reticulum 0.65 -0.44 -2.72 -6.33 -4.98 4.04 1.39 -0.93 -6.20 -3.34 3.90 0.37 -2.03 -10.10 -4.93
Endosome -2.32 12.43 4.68 5.19 -6.52 5.82 9.74 -1.07 -4.42 -6.43 4.43 15.76 1.12 -1.93 -8.26
Golgi -0.61 7.37 0.71 1.03 -2.59 0.17 2.03 -1.21 -1.63 -3.35 0.12 4.77 -0.93 -1.06 -4.13
Lipid Particles 4.28 8.21 5.72 1.19 -9.09 3.98 5.35 1.12 -2.34 -3.50 7.15 9.70 5.06 -2.26 -5.80
Mitochondria 0.13 6.58 -0.98 -0.91 -1.85 1.52 2.00 0.18 -2.38 -3.33 1.46 2.71 -0.65 -2.38 -3.74
Mitotic Spindle -1.71 -3.69 -9.75 -8.57 -9.18 -2.11 -6.24 -7.45 -6.45 -2.83 -3.02 -7.23 -12.29 -10.84 -9.16
None 8.34 7.54 7.64 -3.01 0.92 -1.83 -8.20 -3.01 -1.30 2.36 7.52 6.13 6.65 -2.18 2.28
Nuclear Periphery 2.22 -5.52 -11.29 -16.70 -9.64 5.74 -10.96 -12.69 -17.76 2.15 3.94 -10.10 -13.58 -23.18 -5.69
Nuclear Periphery Foci -2.01 3.54 -3.34 -1.11 -7.82 7.42 2.67 -1.32 -5.70 -3.06 4.12 4.37 -2.14 -7.15 -7.59
Nucleolus 7.95 9.05 7.78 -0.89 -7.49 1.69 1.72 -1.61 -3.64 -3.66 8.01 8.60 3.92 -3.93 -4.68
Nucleus 13.87 -25.82 1.68 -11.29 25.87 3.65 -20.17 -12.53 -16.84 4.88 13.22 -31.19 -7.28 -19.56 20.97
Peroxisomes -3.02 7.92 0.30 2.71 -2.30 -2.34 4.81 -2.40 -1.00 -4.68 -3.34 9.06 -1.34 1.06 -4.99
Vacuole -4.80 -0.23 -32.47 -26.69 -32.36 4.55 -10.96 -23.80 -27.21 -15.96 2.03 -8.64 -39.06 -39.80 -34.15
Vacuole Periphery 1.79 10.84 -1.59 -1.92 -2.99 1.44 2.12 -1.09 -2.54 -3.11 1.75 4.05 -2.04 -3.14 -4.35
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
Standard name
Human Ortholog
Description Spermine synthase; required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
Localization
Cell Percentages cytoplasm (85%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

Spe4

Spe4


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Spe4-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available