Standard name
Human Ortholog
Description Essential 100kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0.38 0.38 0.24 0.14 0.12 0.13 0.14 0.2 – 0.14 0.22 0.22 0.56 0.42 0.46 0.06 0.08 – 0.29 0.24 0.32 0.09 0.14 0.15
Bud 0.19 0.22 0.24 0.23 0.21 0.24 0.22 0.21 – 0.19 0.24 0.23 0.24 0.16 0.16 0 0 – 0.39 0.4 0.31 0.46 0.55 0.55
Bud Neck 0 0 0 0 0 0 0 0 – 0.05 0 0 0 0 0 0 0 – 0.19 0.23 0.2 0.29 0.18 0.14
Bud Site 0.14 0.23 0.18 0.18 0.13 0.1 0.12 0.09 – 0.08 0.1 0.1 0.06 0 0 0 0 – – – – – – –
Cell Periphery 0.1 0.06 0.05 0 0 0 0.06 0.05 – 0.06 0.08 0.09 0.13 0.14 0.19 0.11 0 – 0 0 0 0 0 0
Cytoplasm 0.15 0.13 0.13 0.21 0.15 0.15 0.1 0.12 – 0.08 0.08 0.06 0.17 0.26 0.27 0.74 0.77 – 0 0 0 0 0 0.07
Endoplasmic Reticulum 0 0 0 0 0 0 0 0 – 0 0 0 0 0.07 0.05 0.06 0 – 0 0 0 0 0 0
Endosome 0.08 0.07 0.08 0.1 0.14 0.05 0 0.05 – 0 0 0 0 0 0 0 0.06 – 0 0 0 0 0 0
Golgi 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Mitochondria 0 0.14 0.05 0.12 0.09 0.39 0.39 0.41 – 0.47 0.56 0.52 0 0 0 0 0.05 – 0 0 0 0 0 0
Nucleus 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0.07 0.05 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
Nucleolus 0.06 0.05 0.05 0.05 0.06 0.07 0.07 0.12 – 0.13 0.05 0.05 0 0 0 0 0 – 0 0 0 0 0 0
Peroxisomes 0.13 0.11 0.27 0.2 0.3 0.18 0.22 0.18 – 0.16 0.13 0.19 0.11 0.23 0.18 0 0 – 0 0 0 0 0 0
SpindlePole 0.16 0.09 0.27 0.24 0.2 0.09 0.1 0.08 – 0.08 0.07 0.07 0.18 0.14 0.11 0 0.11 – 0 0 0.06 0 0 0
Vac/Vac Membrane 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0 0 0 – 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 114 112 113 43 54 67 76 114 – 143 122 185 124 112 127 8 5 – 110 86 170 19 50 57
Bud 58 65 113 70 98 122 124 117 – 189 133 194 52 43 44 2 0 – 144 148 164 95 196 215
Bud Neck 6 10 20 9 15 13 11 18 – 46 11 24 1 0 0 0 0 – 71 84 103 59 63 55
Bud Site 44 67 86 55 60 52 66 48 – 77 53 87 13 8 0 3 1 – – – – – – –
Cell Periphery 29 18 23 2 14 13 31 27 – 60 47 76 28 37 54 14 2 – 12 2 5 0 2 4
Cytoplasm 45 38 59 65 70 75 56 67 – 75 47 50 38 69 74 99 49 – 4 4 4 7 14 27
Endoplasmic Reticulum 6 8 3 4 5 21 12 8 – 15 9 16 6 19 13 8 0 – 3 1 5 1 2 2
Endosome 24 20 39 32 65 23 24 26 – 30 5 11 5 10 12 4 4 – 6 7 12 4 5 3
Golgi 8 1 1 0 0 0 0 1 – 1 0 0 3 5 3 1 0 – 1 0 2 0 2 2
Mitochondria 10 42 22 38 43 201 219 231 – 465 311 438 3 0 0 4 3 – 1 7 3 3 5 9
Nucleus 11 7 14 10 16 5 24 16 – 34 17 24 4 3 1 9 3 – 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 0 3 1 1 – 0 2 4 1 0 0 0 0 – 1 0 0 0 0 0
Nucleolus 19 15 21 15 28 37 40 65 – 125 28 42 0 1 0 0 0 – 1 3 1 0 0 0
Peroxisomes 40 31 127 61 137 94 121 103 – 158 71 160 25 60 50 0 0 – 2 3 19 3 2 3
SpindlePole 50 26 127 73 90 47 57 47 – 83 39 57 39 38 31 5 7 – 9 9 31 5 4 4
Vac/Vac Membrane 3 4 7 7 16 5 15 15 – 33 8 8 4 1 2 3 1 – 2 3 1 2 2 4
Unique Cell Count 304 294 465 308 461 511 558 563 990 557 838 221 265 279 133 64 376 366 531 205 356 392
Labelled Cell Count 467 464 775 484 711 778 877 904 1534 903 1376 346 406 411 160 75 376 366 531 205 356 392


Ambiguous, Bud, Bud Neck, Cell Periphery

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 9.3 8.0 7.3 6.3 6.6 5.4 5.7 5.9 – 5.6 5.2 5.6 9.0 9.2 9.4 7.7 8.3 – 8.7 9.4 9.7
Std Deviation (1e-4) 2.3 1.7 1.5 1.8 1.8 1.6 1.7 1.5 – 1.5 1.3 1.3 1.7 2.0 1.7 1.9 2.0 – 1.7 1.7 1.9
Intensity Change (Log2) – – – -0.21 -0.16 -0.45 -0.37 -0.31 – -0.39 -0.49 -0.4 0.29 0.32 0.36 0.06 0.18 – 0.24 0.36 0.4


Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches -3.5 -5.0 -4.5 -4.4 -1.6 – -4.6 -0.9 -0.9 8.2 5.1 6.0 -4.6 -3.0 –
Bud -0.5 -1.1 -0.2 -0.8 -1.3 – -2.3 -0.2 -0.5 -0.2 -2.6 -2.8 -5.9 -4.4 –
Bud Neck -1.0 -0.8 -1.5 -2.2 -0.9 – 0.3 -2.2 -1.4 -2.7 -3.4 -3.5 0 0 –
Bud Site -0.2 -2.3 -3.7 -3.0 -4.7 – -6.0 -4.2 -4.1 -4.4 -6.0 -7.6 -4.6 -3.4 –
Cell Periphery -3.3 -1.5 -2.0 0.4 -0.1 – 0.9 2.2 2.7 3.6 4.3 6.2 2.4 0 –
Cytoplasm 3.1 1.1 0.9 -1.3 -0.4 – -3.1 -2.2 -4.2 1.6 4.6 4.8 14.2 11.9 –
Endoplasmic Reticulum 0 0 3.5 2.0 0 – 1.4 1.4 1.8 0 5.0 3.7 0 0 –
Endosome 0.9 2.8 -2.5 -2.7 -2.5 – -4.5 -5.9 -6.4 -3.1 -2.4 -2.1 -2.1 -0.6 –
Golgi 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Mitochondria 3.9 2.7 12.9 13.0 13.4 – 15.9 17.4 17.2 -2.2 -3.6 -3.7 -0.9 0 –
Nucleus 0.2 0.4 -2.3 1.1 -0.2 – 0.4 0 -0.2 -0.9 -1.6 -2.5 2.0 0 –
Nuclear Periphery 0 0 0 0 0 – 0 0 0 0 0 0 0 0 –
Nucleolus 0.2 1.1 1.8 1.8 4.1 – 4.8 0.4 0.4 -3.2 -3.1 -3.6 0 0 –
Peroxisomes -2.4 0.8 -3.3 -2.1 -3.5 – -5.1 -5.9 -3.4 -4.7 -1.4 -2.9 -6.8 -4.8 –
SpindlePole -1.1 -2.8 -7.4 -7.1 -8.1 – -9.6 -8.8 -10.2 -2.8 -4.0 -5.2 -5.8 -2.8 –
Vacuole 0.8 1.9 -0.7 1.3 1.3 – 2.0 -0.1 -0.9 0 0 0 0 0 –

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 4.986 4.0156 4.6046 4.894 4.4266 4.7533 6.4452 5.7974 6.3877 5.6799 5.8573 6.1504 6.9493 5.3898 5.7294 6.3141 5.7129 6.4111
Actin 0.2696 0.1445 0.1081 0.3243 0.4472 0.2122 0.4349 0.0627 0.1871 0.3633 0.4363 0.2716 0.1876 0.0769 0.081 0.3159 0.2488 0.2131
Bud 0.0565 0.0611 0.3701 0.1481 0.0974 0.0116 0.0146 0.1129 0.239 0.0822 0.0788 0.013 0.0436 0.0911 0.3211 0.1756 0.064 0.0091
Bud Neck 0.1398 0.0169 0.0039 0.0028 0.0421 0.6139 0.0978 0.0069 0.0042 0.0069 0.0434 0.5685 0.0496 0.0123 0.0138 0.0489 0.3218 0.5953
Bud Periphery 0.0713 0.0571 0.3879 0.4613 0.2478 0.0345 0.0332 0.1014 0.3561 0.4775 0.26 0.0339 0.0575 0.0429 0.3405 0.2794 0.2727 0.019
Bud Site 0.2958 0.524 0.1078 0.0397 0.0326 0.0209 0.2361 0.5549 0.1509 0.042 0.1193 0.0279 0.4419 0.5445 0.1641 0.1326 0.0162 0.0193
Cell Periphery 0.0229 0.0073 0.0013 0.0028 0.0049 0.0096 0.0079 0.0044 0.003 0.0075 0.02 0.0112 0.0199 0.005 0.0013 0.0052 0.0056 0.014
Cytoplasm 0.0428 0.0868 0.0019 0.0024 0.02 0.0334 0.0253 0.0983 0.0143 0.0114 0.0098 0.0154 0.029 0.1331 0.0111 0.0052 0.0374 0.058
Cytoplasmic Foci 0.0476 0.04 0.0063 0.0019 0.0674 0.0262 0.058 0.0208 0.0082 0.0006 0.0194 0.0222 0.048 0.0338 0.0114 0.0178 0.0056 0.0309
Eisosomes 0.0015 0.0007 0.0001 0.0003 0.0004 0.0007 0.0027 0.0003 0.0005 0.001 0.0006 0.0011 0.0011 0.0009 0.0002 0.0012 0.0002 0.0012
Endoplasmic Reticulum 0.0012 0.0022 0.0002 0.0002 0.0005 0.0014 0.003 0.0008 0.0019 0.0004 0.0002 0.0002 0.0072 0.0015 0.0001 0.0009 0.0009 0.0007
Endosome 0.0019 0.0087 0.0002 0.001 0.0005 0.005 0.0125 0.0007 0.0024 0.0004 0.0007 0.0038 0.0162 0.0034 0.0011 0.0007 0.008 0.0023
Golgi 0.0048 0.0031 0.0004 0.002 0.0015 0.0117 0.0159 0.0008 0.0027 0.0009 0.0016 0.0092 0.0109 0.004 0.0032 0.0014 0.01 0.0043
Lipid Particles 0.0045 0.0023 0.0002 0.0002 0.0034 0.0012 0.019 0.0006 0.002 0.0001 0.0005 0.0016 0.003 0.0017 0.0033 0.001 0.0008 0.0016
Mitochondria 0.0025 0.0014 0.0009 0.0023 0.0025 0.0032 0.0065 0.0007 0.0072 0.0016 0.0011 0.0009 0.0087 0.0027 0.0028 0.0007 0.0008 0.0015
None 0.0011 0.0235 0.0009 0.0005 0.0087 0.0005 0.0018 0.0157 0.0121 0.0008 0.0021 0.0004 0.0147 0.0219 0.0093 0.0039 0.0003 0.0064
Nuclear Periphery 0.0004 0.0007 0.0002 0.0002 0.0003 0.0001 0.0008 0.0002 0.0007 0.0002 0.0001 0.0001 0.0047 0.0005 0.0001 0.0005 0.0003 0.0001
Nucleolus 0.0023 0.0019 0.0008 0.0001 0.0027 0.001 0.003 0.0009 0.0004 0.0001 0.0003 0.0004 0.0008 0.0014 0.0006 0.001 0.0023 0.001
Nucleus 0.001 0.0039 0.0008 0.0002 0.0015 0.0007 0.0006 0.0008 0.0007 0.0003 0.0003 0.0003 0.0014 0.0017 0.0007 0.0006 0.0007 0.0009
Peroxisomes 0.0277 0.0071 0.0018 0.0086 0.0121 0.0102 0.0197 0.0098 0.0036 0.0003 0.0037 0.017 0.0484 0.0159 0.0322 0.0044 0.0011 0.0178
Punctate Nuclear 0.0018 0.0043 0.0052 0.0002 0.0022 0.0005 0.0039 0.0056 0.0011 0.0001 0.0004 0.0007 0.0012 0.0024 0.0011 0.0013 0.0002 0.0005
Vacuole 0.003 0.0025 0.0007 0.001 0.0037 0.0013 0.0023 0.0008 0.0017 0.0022 0.0014 0.0004 0.0034 0.0022 0.0009 0.0014 0.002 0.0026
Vacuole Periphery 0.0002 0.0003 0.0001 0.0002 0.0005 0.0002 0.0004 0.0001 0.0002 0.0003 0.0001 0.0001 0.0014 0.0003 0.0001 0.0001 0.0005 0.0005

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 22.9876 19.2298 10.9119 20.5576 16.6795 14.3329 20.7776 19.2983 15.8491 22.2899
Translational Efficiency 0.6501 0.7483 1.157 0.5995 0.6715 1.015 0.7216 0.5646 0.7989 0.6148

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✔
Gene Expression ✘
Translational Efficiency ✘

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
320 1628 1066 1484 1704 2127 366 1779 2024 3755 1432 3263

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 965.57 938.55 1065.30 1032.44 776.31 912.22 1086.62 982.74 806.23 923.64 1070.75 1005.34
Standard Deviation 175.00 169.83 146.25 145.16 106.49 130.67 124.52 149.44 138.41 149.49 141.32 149.57
Intensity Change Log 2 — -0.040947 0.141807 0.096605 — 0.232749 0.485143 0.340177 — 0.087480 0.304979 0.210263

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.124736* 0.134754* 0.281101* 0.157069* 0.137501* 0.092758 0.113631* 0.124873* 0.135483* 0.110966* 0.238298* 0.139516*
Bud Neck 0.052790 0.101776 0.078237 0.050893 0.119469 0.170281 0.086486 0.064047 0.108927 0.140580 0.080345 0.058065
Bud Site 0.512688* 0.595763* 0.491024* 0.659957* 0.552853* 0.611165* 0.727256* 0.671996* 0.546503* 0.604487* 0.551402* 0.666521*
Cell Periphery 0.020870 0.020983 0.007981 0.017008 0.017270 0.037370 0.008475 0.024897 0.017839 0.030265 0.008107 0.021309
Cytoplasm 0.095354 0.059642 0.052172 0.078072 0.072049 0.047605 0.038604 0.083886 0.075734 0.052824 0.048704 0.081242
Cytoplasmic Foci 0.034210 0.029484 0.022748 0.005011 0.027837 0.011486 0.005618 0.005544 0.028845 0.019289 0.018370 0.005302
Eisosomes 0.003457 0.001801 0.001910 0.003220 0.002198 0.001653 0.003610 0.004354 0.002397 0.001717 0.002345 0.003838
Endoplasmic Reticulum 0.004233 0.000389 0.001462 0.000375 0.000589 0.000231 0.000170 0.000221 0.001165 0.000300 0.001132 0.000291
Endosome 0.032208 0.007800 0.005759 0.002612 0.010321 0.003131 0.000698 0.001416 0.013782 0.005155 0.004465 0.001960
Golgi 0.023698 0.005910 0.004263 0.002839 0.008336 0.002557 0.000378 0.001640 0.010765 0.004011 0.003270 0.002185
Lipid Particles 0.008543 0.002100 0.004159 0.000149 0.001006 0.000250 0.000096 0.000148 0.002198 0.001052 0.003121 0.000148
Mitochondria 0.003621 0.006655 0.000861 0.004106 0.010573 0.008674 0.000345 0.001933 0.009474 0.007799 0.000729 0.002921
Mitotic Spindle 0.007607 0.002142 0.002863 0.003864 0.001257 0.001362 0.002209 0.003492 0.002260 0.001700 0.002696 0.003661
None 0.000097 0.000814 0.000066 0.000083 0.001029 0.000162 0.000065 0.000131 0.000881 0.000445 0.000066 0.000109
Nuclear Periphery 0.000152 0.000019 0.000023 0.000034 0.000008 0.000005 0.000011 0.000019 0.000031 0.000011 0.000020 0.000026
Nuclear Periphery Foci 0.000819 0.000446 0.000514 0.000122 0.000194 0.000062 0.000105 0.000059 0.000293 0.000229 0.000409 0.000088
Nucleolus 0.000361 0.000966 0.000036 0.000033 0.000147 0.000035 0.000019 0.000015 0.000181 0.000439 0.000032 0.000023
Nucleus 0.003065 0.001592 0.001532 0.000493 0.001104 0.000378 0.000718 0.000706 0.001414 0.000905 0.001324 0.000609
Peroxisomes 0.018339 0.021971 0.027429 0.004796 0.029981 0.007624 0.004237 0.004989 0.028140 0.013844 0.021502 0.004901
Vacuole 0.048964 0.004273 0.015746 0.007337 0.005728 0.003005 0.007206 0.005312 0.012564 0.003555 0.013563 0.006233
Vacuole Periphery 0.004187 0.000721 0.000115 0.001927 0.000548 0.000205 0.000063 0.000322 0.001123 0.000429 0.000102 0.001052

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -0.76 -8.68 -2.03 -2.01 9.11 5.57 1.77 1.57 -3.96 -0.81 3.43 -9.21 -0.34 -4.32 9.44
Bud Neck -5.54 -2.77 0.18 9.09 4.56 -7.01 3.56 9.52 17.36 2.37 -5.55 4.84 10.44 19.35 4.46
Bud Site -3.74 0.98 -6.30 -4.91 -12.10 -5.47 -9.57 -10.16 -5.48 3.11 -6.23 0.02 -11.98 -7.32 -10.48
Cell Periphery -0.12 2.47 0.69 1.75 -4.62 -7.52 3.10 -2.74 4.12 -4.90 -5.99 5.65 -1.56 4.53 -7.71
Cytoplasm 3.76 3.96 1.50 -4.10 -4.32 5.57 4.27 -3.05 -8.46 -6.47 5.83 4.68 -2.18 -9.04 -7.11
Cytoplasmic Foci 1.01 2.06 5.86 10.46 8.55 7.02 8.61 10.10 3.78 0.23 4.39 3.91 12.00 10.45 8.17
Eisosomes 2.13 1.99 0.27 -3.01 -2.71 1.46 -1.01 -3.13 -4.19 -0.54 2.11 0.18 -2.96 -5.14 -2.81
Endoplasmic Reticulum 2.44 1.71 2.45 0.05 3.35 4.84 5.31 5.02 0.12 -0.97 3.35 0.01 3.35 0.01 3.52
Endosome 4.23 4.59 5.20 4.48 3.17 6.36 8.78 7.99 3.35 -1.63 6.32 6.51 8.94 5.45 3.76
Golgi 3.70 4.07 4.35 3.02 1.37 6.34 9.25 6.84 1.62 -2.51 6.15 6.55 7.59 3.30 1.62
Lipid Particles 2.45 1.64 3.39 2.48 5.13 4.07 5.31 4.91 0.84 -0.79 2.06 -1.37 4.86 2.58 5.09
Mitochondria -2.04 2.51 -0.39 1.87 -3.74 1.23 9.61 7.41 5.51 -3.21 1.38 9.55 6.40 5.31 -4.56
Mitotic Spindle 2.06 1.72 1.44 -1.89 -0.77 -0.36 -1.12 -2.76 -2.62 -1.18 1.20 -0.76 -1.90 -3.25 -1.16
None -2.33 1.03 0.55 2.38 -0.63 2.08 2.29 2.12 0.50 -1.35 1.15 2.31 2.18 2.44 -1.48
Nuclear Periphery 2.57 2.38 2.22 -1.21 -0.42 2.89 -1.66 -1.38 -1.71 -0.64 2.33 0.59 0.27 -2.10 -0.25
Nuclear Periphery Foci 1.19 0.65 2.39 2.82 4.58 3.89 1.44 3.74 -0.07 1.45 0.89 -2.17 3.53 2.72 5.19
Nucleolus -0.80 1.06 1.07 2.06 0.36 2.99 3.46 3.58 2.26 1.02 -1.16 2.26 2.40 2.11 1.42
Nucleus 1.99 1.80 3.38 2.31 4.56 3.80 -0.15 0.36 -3.58 0.42 2.05 -0.74 2.94 0.42 3.69
Peroxisomes -0.97 -2.16 3.80 8.10 8.70 9.63 10.21 10.70 2.34 -0.40 6.65 2.51 11.55 7.95 8.46
Vacuole 6.34 3.94 5.36 -3.84 3.24 3.14 -1.71 -1.14 -3.88 1.28 6.59 -2.10 2.52 -5.44 4.15
Vacuole Periphery 2.59 3.09 1.53 -1.85 -2.93 3.57 5.06 1.67 -1.07 -2.36 2.89 4.56 0.18 -2.07 -3.29
Standard name
Human Ortholog
Description Essential 100kDa subunit of the exocyst complex; the exocyst mediates polarized targeting and tethering of post-Golgi secretory vesicles to active sites of exocytosis at the plasma membrane prior to SNARE-mediated fusion
Localization
Cell Percentages actin (20%)
Cell Cycle Regulation No
Subcompartmental Group N/A

Sec10

Sec10


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Sec10-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available