ORF
Human Ortholog
Description Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; not an essential gene; YLR177W has a paralog, PSP1, that arose from the whole genome duplication
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Micrographs

ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm 0.96 0.98 0.98 0.97 – 0.93 0.92 0.9 0.78 0.82 0.67 0.8 1.0 0.99 0.98 0.93 0.91 0.92 0.92 0.92 0.74 0.99 0.88 0.89
Endoplasmic Reticulum 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0.09 0.08 0.08 0 0 0 0 0 0
Endosome 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0.05 0 0 0 – 0.08 0.07 0.09 0.25 0.15 0.42 0.22 0 0 0 0 0 0 0 0 0.16 0 0 0
Nucleus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
Vac/Vac Membrane 0 0 0 0 – 0 0 0 0 0.06 0 0.06 0 0 0 0 0.05 0.06 0 0 0 0 0 0
ensLOC DeepLoc
Localization WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 WT1 WT2 WT3 AF100 AF140 AF180
Cortical Patches 0 0 0 1 – 0 1 3 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 2
Bud 1 0 0 0 – 3 2 2 7 4 3 5 0 0 0 0 0 0 0 2 0 0 0 2
Bud Neck 0 0 0 2 – 4 8 2 0 0 0 1 0 0 0 0 0 0 1 0 0 0 1 0
Bud Site 0 0 0 0 – 0 1 0 0 0 0 0 0 0 0 0 0 0 – – – – – –
Cell Periphery 1 6 0 1 – 4 4 2 2 5 3 6 0 0 0 4 6 3 0 1 1 0 0 0
Cytoplasm 128 408 59 149 – 299 411 485 256 304 226 265 21 89 135 164 173 162 128 386 70 34 85 145
Endoplasmic Reticulum 1 3 0 0 – 1 3 1 2 4 1 0 0 0 2 16 15 15 0 0 0 0 0 0
Endosome 0 1 0 0 – 1 1 6 7 3 10 5 0 0 0 4 5 4 0 4 1 0 1 1
Golgi 1 1 0 0 – 0 0 0 1 1 0 0 0 0 1 3 0 0 0 1 0 0 0 0
Mitochondria 7 2 1 5 – 27 32 50 81 54 142 74 0 0 0 7 6 5 4 9 15 0 0 2
Nucleus 0 1 1 1 – 2 0 2 1 1 2 2 0 0 0 0 0 0 0 1 1 0 0 0
Nuclear Periphery 0 0 0 0 – 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1
Nucleolus 0 0 0 0 – 0 0 2 0 0 0 0 0 1 0 0 2 1 0 0 0 0 0 0
Peroxisomes 0 0 0 0 – 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0
SpindlePole 0 0 0 0 – 1 3 0 1 1 5 3 0 0 0 0 1 1 0 1 0 0 1 1
Vac/Vac Membrane 0 0 0 0 – 5 11 16 7 24 10 19 0 1 0 2 9 10 0 3 2 0 0 1
Unique Cell Count 133 416 60 154 321 445 540 330 372 339 333 21 90 138 177 191 177 139 420 96 35 97 163
Labelled Cell Count 139 422 61 159 347 477 571 365 401 403 380 21 91 138 200 218 202 139 420 96 35 97 163


Cytoplasm

(Huh et al. Nature 2003 425:686)
Screen WT1 WT2 WT3 RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3 AF100 AF140 AF180
Mean Cell GFP Intensity (1e-4) 3.8 5.0 4.6 5.1 – 5.2 5.3 5.7 4.7 4.9 4.5 4.8 4.8 5.5 6.1 6.4 6.6 6.4 – 4.8 5.8
Std Deviation (1e-4) 0.5 0.9 0.4 1.7 – 1.6 1.4 1.6 1.2 1.1 1.3 1.3 0.7 0.9 1.3 1.7 2.1 2.1 – 1.2 1.8
Intensity Change (Log2) – – – 0.17 – 0.18 0.22 0.31 0.04 0.1 -0.03 0.06 0.07 0.26 0.41 0.49 0.53 0.48 – 0.07 0.34

WT3RAP60RAP220RAP300RAP380RAP460RAP540RAP620RAP70002468WT3HU80HU120HU16002468WT3rpd3Δ_1rpd3Δ_2rpd3Δ_302468WT1AF140AF18002468
rapamycinhydroxy-urearpd3 knockoutalpha-factorMultiple Condition Time-Course Intensity PlotsGFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)GFP Intensity (1e-4)

Localization RAP60 RAP140 RAP220 RAP300 RAP380 RAP460 RAP540 RAP620 RAP700 HU80 HU120 HU160 rpd3Δ_1 rpd3Δ_2 rpd3Δ_3
Cortical Patches 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Neck 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Bud Site 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Cell Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Cytoplasm -0.6 – -1.5 -1.7 -2.2 -3.8 -3.3 -5.0 -3.5 0.6 0.3 -0.2 -1.6 -2.0 -1.8
Endoplasmic Reticulum 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Endosome 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Golgi 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Mitochondria 0 – 0 0 2.0 0 2.8 0 0 0 0 0 0 0 0
Nucleus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nuclear Periphery 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Nucleolus 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Peroxisomes 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
SpindlePole 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0
Vacuole 0 – 0 0 0 0 0 0 0 0 0 0 0 0 0

Images

Circle plot not available

Protein Concentration and Protein Localization Data

R1 R2 R3
G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Pre-START G1 Post-START S/G2 Metaphase Anaphase Telophase
Concentration 0.0871 0.0023 -0.1827 -0.4814 0.4922 -0.1771 -0.0192 0.4623 0.1861 0.3883 0.3533 0.2484 -0.5347 -0.2975 -0.6069 -0.5544 -0.5969 -0.6312
Actin 0.0193 0.0088 0.0136 0.002 0.0036 0.0094 0.0103 0.0001 0.0081 0.0073 0.017 0.0112 0.03 0.0006 0.0193 0.0308 0.0187 0.0023
Bud 0.0089 0.002 0.0065 0.0017 0.0013 0.0008 0.0021 0.0001 0.0008 0.0009 0.0044 0.0003 0.0006 0.0017 0.0014 0.0047 0.0082 0.0013
Bud Neck 0.0211 0.0003 0.0128 0.0002 0.0015 0.0003 0.0047 0.0001 0.0027 0.0036 0.0011 0.0007 0.0139 0.0002 0.0007 0.0002 0.0018 0.0016
Bud Periphery 0.0101 0.0026 0.0024 0.007 0.001 0.0033 0.0052 0.0001 0.0013 0.0008 0.0095 0.0005 0.0012 0.0025 0.0015 0.0047 0.0154 0.0018
Bud Site 0.021 0.0121 0.0206 0.0006 0.0293 0.0002 0.004 0.0018 0.0037 0.0044 0.0124 0.0003 0.0063 0.0045 0.0057 0.0004 0.0085 0.0006
Cell Periphery 0.0005 0.0002 0.0007 0.0002 0.0005 0.0001 0.0004 0.0002 0.0005 0.0001 0.0003 0.0001 0.0006 0.0001 0.0002 0.0001 0.0002 0.0001
Cytoplasm 0.1364 0.257 0.1861 0.2251 0.1401 0.1898 0.3637 0.4685 0.3526 0.3354 0.383 0.4212 0.2391 0.2912 0.2436 0.305 0.1539 0.3289
Cytoplasmic Foci 0.0629 0.0071 0.0242 0.0227 0.0257 0.0152 0.0197 0.0045 0.0166 0.0352 0.0202 0.0193 0.0249 0.0139 0.0102 0.0073 0.0396 0.0188
Eisosomes 0.0004 0.0002 0.0004 0.0002 0.0017 0.0002 0.0005 0.0001 0.0004 0.0002 0.0002 0.0001 0.0007 0 0.0002 0.0001 0.0002 0
Endoplasmic Reticulum 0.0063 0.0031 0.0029 0.0029 0.0066 0.0009 0.0034 0.0022 0.0026 0.0017 0.0027 0.0023 0.004 0.001 0.0037 0.002 0.002 0.0014
Endosome 0.0464 0.0016 0.0123 0.014 0.0102 0.0032 0.0082 0.0017 0.014 0.0098 0.0161 0.009 0.0126 0.0013 0.006 0.0034 0.0322 0.0075
Golgi 0.0147 0.0003 0.0065 0.0009 0.0051 0.0035 0.0019 0.0001 0.0041 0.0025 0.0037 0.0026 0.0035 0.0001 0.0013 0.0005 0.0107 0.0011
Lipid Particles 0.0187 0.0005 0.0047 0.0009 0.0161 0.0073 0.0064 0.0002 0.0041 0.0177 0.0441 0.0015 0.0084 0.0002 0.0014 0.0002 0.0228 0.0019
Mitochondria 0.0204 0.0004 0.0088 0.007 0.0054 0.0122 0.0012 0.0002 0.0104 0.0013 0.0027 0.0021 0.0054 0.0002 0.0012 0.0006 0.0058 0.0013
None 0.5542 0.6988 0.6567 0.691 0.6186 0.744 0.5397 0.5171 0.5588 0.5248 0.4709 0.5192 0.6092 0.6733 0.6839 0.6303 0.6199 0.6086
Nuclear Periphery 0.0047 0.0007 0.0026 0.0022 0.0329 0.0009 0.0058 0.0004 0.001 0.0008 0.0014 0.0023 0.0056 0.0006 0.0052 0.0014 0.0071 0.0016
Nucleolus 0.0033 0.0001 0.0019 0.0005 0.0085 0.0001 0.0005 0.0001 0.0004 0.0016 0.0003 0.0003 0.0011 0.0002 0.0004 0.0006 0.0015 0.0028
Nucleus 0.0049 0.0009 0.0035 0.0022 0.008 0.0005 0.0027 0.0009 0.0012 0.0027 0.0012 0.0018 0.0109 0.0025 0.0027 0.0029 0.0037 0.0035
Peroxisomes 0.0206 0.0018 0.0122 0.0111 0.0624 0.0051 0.0141 0 0.012 0.0346 0.002 0.0017 0.0098 0.0008 0.0058 0.0006 0.0271 0.0012
Punctate Nuclear 0.0186 0.0008 0.007 0.0048 0.0169 0.002 0.0033 0.0003 0.0009 0.0134 0.001 0.0011 0.0093 0.0037 0.0037 0.0026 0.018 0.0106
Vacuole 0.005 0.0008 0.0112 0.0023 0.0025 0.0004 0.0018 0.0012 0.0031 0.001 0.0048 0.0016 0.002 0.0012 0.0013 0.0014 0.0018 0.0023
Vacuole Periphery 0.0018 0.0001 0.0022 0.0005 0.0022 0.0003 0.0003 0.0001 0.0006 0.0002 0.0012 0.0006 0.0008 0.0001 0.0004 0.0003 0.0007 0.0006

Sequencing Data

R1 R2
G1 Post-START S/G2 Metaphase Anaphase Telophase G1 Post-START S/G2 Metaphase Anaphase Telophase
Gene Expression 7.3093 6.2727 12.4122 11.0321 14.7837 12.8572 16.12 20.3329 19.7376 16.6941
Translational Efficiency – – – – – – – – – –

Hit Data

Dataset Hit
Protein Concentration ✘
Protein Localization ✘
Gene Expression ✘
Translational Efficiency –

Micrographs

Cell Count

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
78 1558 361 107 1347 2112 157 1502 1425 3670 518 1609

Protein Abundance

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Mean 628.71 695.11 994.68 954.49 645.56 700.67 1040.53 696.01 644.64 698.31 1008.58 713.20
Standard Deviation 58.94 102.93 120.66 129.35 75.02 88.51 117.44 78.47 74.33 94.94 121.53 104.92
Intensity Change Log 2 — 0.144847 0.661838 0.602335 — 0.118184 0.688695 0.108557 — 0.131401 0.675507 0.373232

Localization Score (DeepLoc)

R1 R2 R1 & R2
WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14 WT UBP2 UBP14 UBP2UBP14
Actin 0.000102 0.000190 0.000935 0.000388 0.000075 0.000293 0.000619 0.000064 0.000076 0.000249 0.000839 0.000086
Bud Neck 0.008480 0.015419 0.005169 0.001497 0.011207 0.026517 0.002351 0.004717 0.011058 0.021805 0.004315 0.004503
Bud Site 0.000957 0.008621 0.011176 0.006934 0.001948 0.013177 0.005532 0.003531 0.001894 0.011243 0.009466 0.003758
Cell Periphery 0.000310 0.000088 0.000292 0.000257 0.000137 0.000136 0.000334 0.000448 0.000147 0.000115 0.000305 0.000435
Cytoplasm 0.460866 0.546234 0.439439 0.404448 0.485419 0.491744 0.446068 0.509693 0.484075 0.514876 0.441448 0.502694
Cytoplasmic Foci 0.301822 0.166751 0.026934 0.043893 0.255819 0.203928 0.020204 0.047021 0.258337 0.188145 0.024894 0.046813
Eisosomes 0.000330 0.000076 0.000086 0.000109 0.000179 0.000110 0.000101 0.000170 0.000187 0.000095 0.000091 0.000166
Endoplasmic Reticulum 0.001384 0.000751 0.008478 0.004908 0.000686 0.000554 0.008377 0.000369 0.000724 0.000637 0.008447 0.000670
Endosome 0.012213 0.015191 0.009305 0.011316 0.012043 0.019048 0.008361 0.003310 0.012053 0.017411 0.009019 0.003843
Golgi 0.001686 0.001941 0.000230 0.000155 0.002037 0.003131 0.000192 0.000626 0.002018 0.002626 0.000218 0.000594
Lipid Particles 0.018755 0.005520 0.003689 0.004352 0.011588 0.005621 0.004261 0.002053 0.011981 0.005578 0.003863 0.002206
Mitochondria 0.004613 0.004249 0.001427 0.000153 0.005793 0.006542 0.000263 0.001694 0.005728 0.005569 0.001074 0.001591
Mitotic Spindle 0.000026 0.002444 0.009688 0.000401 0.000368 0.006431 0.007339 0.002384 0.000349 0.004739 0.008976 0.002252
None 0.002357 0.004051 0.002792 0.002154 0.002875 0.004158 0.003808 0.007567 0.002847 0.004112 0.003100 0.007207
Nuclear Periphery 0.000894 0.000534 0.002002 0.001272 0.000638 0.000487 0.002055 0.000631 0.000652 0.000507 0.002018 0.000674
Nuclear Periphery Foci 0.000260 0.000657 0.007716 0.010261 0.000303 0.000268 0.009747 0.000237 0.000301 0.000433 0.008332 0.000904
Nucleolus 0.009518 0.002053 0.000465 0.000374 0.000979 0.001870 0.000369 0.000948 0.001446 0.001948 0.000436 0.000910
Nucleus 0.136451 0.143034 0.260096 0.271142 0.160232 0.135425 0.231759 0.373468 0.158930 0.138655 0.251508 0.366663
Peroxisomes 0.004223 0.005869 0.000662 0.000456 0.006126 0.007316 0.000367 0.001040 0.006022 0.006702 0.000572 0.001001
Vacuole 0.033586 0.074597 0.208812 0.235298 0.040619 0.071261 0.247635 0.039643 0.040234 0.072677 0.220579 0.052654
Vacuole Periphery 0.001168 0.001729 0.000606 0.000232 0.000930 0.001984 0.000259 0.000387 0.000943 0.001876 0.000501 0.000377

Localization Changes (T-score)

R1 R2 R1 & R2
UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14 UBP2_WT UBP14_WT UBP2UBP14_WT UBP2UBP14_UBP2 UBP2UBP14_UBP14
Actin -1.55 -8.21 -4.25 -4.25 5.72 -2.74 -9.01 0.51 2.81 8.91 -3.72 -11.71 -0.66 3.29 11.31
Bud Neck -3.33 1.57 4.43 10.44 3.68 -8.35 6.85 4.88 13.43 -1.91 -7.30 4.78 5.20 14.22 0.38
Bud Site -6.63 -4.77 -2.63 0.87 1.53 -8.78 -6.80 -2.14 6.69 2.88 -10.47 -5.15 -2.61 6.83 3.60
Cell Periphery 2.52 0.14 1.07 -4.67 2.72 0.20 -5.97 -6.79 -6.68 -2.89 3.05 -8.99 -6.62 -7.45 -2.82
Cytoplasm -2.78 3.23 3.25 8.02 0.65 -0.60 8.55 -1.98 -1.51 -9.45 -3.42 10.48 -1.07 2.18 -11.25
Cytoplasmic Foci 6.11 12.95 12.38 23.06 -2.58 7.29 40.40 34.90 32.32 -12.56 10.99 41.85 36.72 38.19 -11.56
Eisosomes 5.21 4.71 4.46 -2.96 -0.76 8.00 5.68 0.91 -3.45 -2.82 11.01 9.12 1.69 -4.46 -3.72
Endoplasmic Reticulum 1.02 -9.25 -4.02 -6.64 5.57 0.95 -9.95 2.07 2.23 10.31 0.59 -15.83 0.08 -0.95 16.12
Endosome -1.05 1.10 1.21 3.73 0.39 -4.68 3.70 7.61 14.32 5.42 -4.13 2.93 7.65 16.22 7.84
Golgi -0.34 2.67 2.86 5.94 4.19 -2.42 7.82 4.34 5.69 -1.77 -1.73 7.93 4.63 6.13 -1.56
Lipid Particles 3.39 3.78 3.84 2.56 0.58 6.37 7.93 10.80 9.11 4.57 7.16 9.06 11.38 10.49 7.32
Mitochondria 0.32 2.61 3.45 6.30 2.22 -0.52 4.41 3.18 5.96 -3.12 0.16 4.02 3.39 6.38 -1.39
Mitotic Spindle -4.02 -2.49 -2.26 2.08 2.22 -5.47 -1.68 -2.22 3.04 0.93 -6.25 -2.80 -2.28 2.47 2.00
None -1.91 0.09 0.71 3.82 1.12 -1.77 0.53 -4.57 -3.04 -4.69 -2.14 1.01 -4.50 -3.24 -5.53
Nuclear Periphery 0.90 -3.91 -1.49 -7.78 6.07 1.39 -9.75 -0.53 -3.66 10.47 1.41 -13.93 -0.93 -5.13 17.42
Nuclear Periphery Foci -4.83 -13.28 -4.82 -4.55 0.04 0.81 -8.26 0.81 -0.00 8.30 -3.10 -15.55 -3.92 -2.72 14.23
Nucleolus 1.46 1.78 1.83 7.61 3.26 -3.45 6.59 0.16 3.17 -3.70 -1.68 3.50 1.59 4.44 -2.85
Nucleus -0.48 -6.68 -3.40 -3.84 1.83 4.27 -4.76 -25.85 -30.91 -6.58 3.84 -9.60 -25.73 -31.54 -8.46
Peroxisomes -1.50 3.68 3.98 8.57 1.99 -1.30 8.62 7.23 10.58 -3.14 -0.85 8.51 7.54 12.29 -1.94
Vacuole -4.85 -15.41 -11.01 -9.84 -2.51 -11.28 -14.99 -2.47 7.48 14.64 -14.17 -22.98 -7.31 1.84 19.94
Vacuole Periphery -1.47 2.40 3.84 6.23 2.72 -3.81 5.04 3.61 6.49 -2.07 -4.23 3.40 3.98 8.20 0.58
Protein Complexes26S Proteasome complex37S mitochondrial small ribosomal subunit54S mitochondrial large ribosomal subunit60S cytosolic large ribosomal subunitAar2-U5 snRNPAnaphase-Promoting Complex variant 1Anaphase-Promoting Complex variant 2Anaphase-Promoting Complex variant 3Anaphase-Promoting Complex variant 4Arp2/3 complexATG1 kinase complexBLOC-1 complexCcr4-Not complexCentral kinetochore CTF19 complexCleavage and polyadenylation specificity factorcomplexCMG helicase complexCMG-Pol epsilon complexCOMPASS complexCOP9 signalosome COPI vesicle coat complexCoQ6 biosynthesis complexCore mediator complexCORVET complexCTF18-RFC complexCURI complex variant 1CURI complex variant 2CURI complex variant 3Cytoplasmic exosome complex, DIS3 variantDASH complexDNA-directed RNA Polymerase I complexDNA-directed RNA polymerase II complexDNA-directed RNA polymerase III complexDNA replication factor C complexEGO complexELG1-RFC complex Elongator holoenzyme complexEndoplasmic Reticulum Membrane ComplexEukaryotic translation initiation factor 2BcomplexEukaryotic translation initiation factor 3core complexExocystExomer complexFAR complexGeneral transcription factor complex TFIIDGeneral transcription factor complex TFIIHGET4-GET5 transmembrane domain recognition complexGID ubiquitin ligase complexGin4 complexGolgi transport complexGSE complexHMC complexHOPS complexINO80 chromatin remodeling complexLSM1-7 complexLsm1-7-Pat1 complexLSM2-7 complexLSM2-8 complexMCM complexMICOS complexMitochondrial electron transport complex IIIMitochondrial inner membrane pre-sequence translocasecomplexMitochondrial outer membrane translocase holocomplexMitochondrial proton-transporting ATP synthase complexMitochondrial pyruvate dehydrogenase complexNineTeen complexNOP8 60s ribosome pre-assembly complexNuA3 histone acetyltransferase complexNuA4 histone acetyltransferase complexNuclear condensin complexNuclear/nucleolar exosome complex, DIS3-RRP6 variantNuclear pore complexNucleolar ribonuclease MRP complexNucleolar ribonuclease P complexOligosaccharyl transferase complex variant 1Oligosaccharyl transferase complex variant 2PAF1 complexPAS complexPhosphatidylinositol 3-kinase complex IPolarisomePrefoldin complexPRP19-associated complexRad17 RFC-like complexRetromer complexRPD3L histone deacetylase complexRPD3S histone deacetylase complexRQC complexRSC complex variant RSC1RSC complex variant RSC2SAGA complexSCF-Met30 ubiquitin ligase complexSCF-Ufo1 ubiquitin ligase complexSEA complexSeptin complexSET3C histone deacetylase complexSignal recognition particleSLIK (SAGA-like) complexSmall ribosomal subunit processome, variant1Small ribosomal subunit processome, variant2Small ribosomal subunit processome, variant3SMC5-SMC6 SUMO ligase complexSm complexSpliceosomal commitment complexSPOTS complexSWI/SNF chromatin remodelling complexSwr1 chromatin remodelling complexTHO complexTranscription factor TFIIIC complexTranslocon complexTRAPPIII protein complexTRAPPII protein complexTRAPPI protein complexTREX complexU1 snRNPU2 snRNPU4 snRNPU4/U6 snRNPU4/U6.U5 tri-snRNP complexU5 snRNPU6 snRNP complexUTP-A complexUTP-B complexUTP-C complex variant 1UTP-C complex variant 2UTP-C complex variant 3Vacuolar proton translocating ATPase complex,Golgi variantVacuolar proton translocating ATPase complex,vacuole variantCellular Components••••••••••••••••actinbud neckcell peripherycytoplasmendosomeERGolgimitochondrionmixednuclear peripherynucleolusnucleusperoxisomespindle polevacuolar membranevacuole
ORF
Human Ortholog
Description Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; not an essential gene; YLR177W has a paralog, PSP1, that arose from the whole genome duplication
Localization
Cell Percentages cytoplasm (16%)
Cell Cycle Regulation No
Subcompartmental Group cytoplasm-9

YLR177W

YLR177W


Nearest neighbours ( genes)

correlation threshold

0.6

1.0

0.80


Biological Process (Gene Ontology)
Molecular Function (Gene Ontology)
Cellular Component (Gene Ontology)

Endocytosis
Temp Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Vph1-GFP)
37℃
RT
Cell Cycle Omics

CYCLoPs (Ylr177w-GFP)
Gene / Allele Actin Patch (Sac6-tdTomato) Cortical Patch (Sla1-GFP) Late Endosome (Snf7-GFP) Vacuole (Sac6-tdTomato)
Gene Images
Gene Images
Images are not yet available
Images are not yet available